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"Latar belakang. Gagal jantung akut merupakan salah satu masalah kesehatan utama di seluruh dunia. Gagal jantung akut sering disertai dengan gagal ginjal kronik sebagai penyakit penyerta.Tujuan. Mengetahui hubungan antara riwayat gagal ginjal kronik dengan mortalitas pada pasien gagal jantung akut, yang dapat digunakan sebagai masukan untuk lebih mengoptimalkan penatalaksanaan pasien gagal jantung akut dengan riwayat gagal ginjal kronik di rumah sakit di Indonesia.Metode. Penelitian dilakukan dengan desain potong lintang dengan sampel berupa data sekunder pasien dengan diagnosis gagal jantung akut dari studi Acute Decompensated Heart Failure Registry (ADHERE) di lima rumah sakit di Indonesia pada bulan Desember 2005 - Desember 2006.Hasil. Sampel seluruhnya berjumlah 882, terdiri dari 68,5% laki-laki dan 31,5% perempuan dengan rerata usia 59 tahun. Sampel dengan riwayat gagal ginjal kronik sebanyak 154 orang (68,2% laki-laki, 31,8% perempuan, rerata usia 56 tahun). Angka mortalitas di rumah sakit seluruh sampel 4,2%. Angka mortalitas sampel dengan riwayat gagal ginjal kronik 7,1%, hampir dua kali lipat angka mortalitas sampel tanpa riwayat gagal ginjal kronik, yang sebesar 3,6%. Didapatkan p = 0,045, OR = 2,07, dan CI 95% = 1,003 - 4,299.Kesimpulan. Terdapat hubungan bermakna antara riwayat gagal ginjal kronik dengan mortalitas di rumah sakit pada pasien gagal jantung akut. Risiko timbulnya mortalitas pada sampel dengan riwayat gagal ginjal kronik adalah dua kali lipat risiko tersebut pada sampel tanpa riwayat gagal ginjal kronik.

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Background. Acute heart failure is one of the major health problem around the world. Acute heart failure and chronic renal failure are often coexist.

Objective. In order to answer the question whether there is a significant correlation between previously diagnosed chronic renal failure and in-hospital mortality on patients with acute heart failure, so the result can be used as a suggestion to improve the quality of therapy on hospitalized acute heart failure patients.

Method. This study use cross sectional method with sample taken from secondary data of patient diagnosed for acute heart failure on Study Acute Decompensated Heart Failure Registry (ADHERE) in five hospitals in Indonesia on December 2005 - December 2006.

Result. Total sample is account for 882 patients, consist of 68,5% men and 31,5% women, with mean of age 59 years old. Sample with previously diagnosed chronic renal failure consist of 154 patients (68,2% men, 31,8% women, mean of age 56 years old). In-hospital mortality rate is 4,2% on total sample. In-hospital mortality rate on sample with previously diagnosed chronic renal failure is 7,1%, almost two times higher than in-hospital mortality rate on sample without previously diagnosed chronic renal failure, which is only 3,6% (p = 0,045, OR = 2,07, dan CI 95% = 1,003 - 4,299).

Conclusion. There is significant correlation between previously diagnosed chronic renal failure and in-hospital mortality on patients with acute heart failure. The risk for sample with previously diagnosed chronic renal failure to developed mortality during hospitalization is two times higher than sample without previously diagnosed chronic renal failure."

"Latar Belakang: Post-stroke fatigue merupakan invisible handicap dengan prevalensi global 23% - 85%. Faktor yang berkaitan multidimensional, dan berdampak negatif terhadap angka rawat, luaran fungsional, kualitas hidup, dan kesintasan. Prevalensi dan faktor-fakor yang berkaitan dengan late PSF pada populasi stroke iskemik di Indonesia belum ada. Metode: Penelitian potong-lintang ini menggunakan teknik pengambilan sampel berurutan pada seluruh pasien stroke iskemik yang kontrol ke Poli Saraf RSUPN Dr. Cipto Mangunkusumo. Data primer didapatkan menggunakan kuisioner Fatigue Severity Scale, Skala Kecemasan dan Depresi Rumah Sakit, Montreal Cognitive Assessment, dan Pittsburgh Sleep Quality Index versi Indonesia. Data sekunder didapatkan dari rekam medis. Analisis dilakukan untuk menilai prevalensi, hubungan PSF dengan faktor-faktor yang memengaruhi, dan korelasi item FSS dengan PSF.

Hasil: Dari 248 pasien, 100 pasien pertama yang memenuhi kriteria penelitian diambil sebagai subjek penelitian. Prevalensi PSF didapatkan sebanyak 49%. Pada analisis multivariate, pekerjaan sebelum stroke (aOR 0,34; IK95% (0,11-0,99); p=0,047), jumlah komorbid (aOR 3,07; IK95% (1,17-8,10); p=0,023), dan talamus (aOR 0,17; IK95% (0,03-0,89); p=0,036) menentukan kejadian PSF. Pada uji korelasi, item FSS yang berkorelasi tertinggi adalah item 8 dan 5.

Simpulan: Pada penelitian ini, hampir setengah pasien stroke iskemik mengalami late PSF. Faktor-faktor yang berkaitan perlu diinterpretasi secara hati-hati. Fatigue bersifat subjektif sehingga faktor psikososial dan budaya perlu dipertimbangkan.

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Background: Post-stroke fatigue is an invisible handicap with a global prevalence of 23%-85%. The factors associated is multidimensional, and has negatif impact on hospitalization, functional outcome, quality of life, and survival. The prevalence and factors associated with late PSF among the Indonesian population with ischemic stroke has not been published.

Methods: This is a cross-sectional study using consecutive sampling techniques on stroke ischemic patients who visits the Neurolgy clinic at Dr. Cipto Mangunkusumo Hospital. Primary data is obtained by questionnaires consisting of the Indonesian version of the Fatigue Severity Scale, Hospital Anxiety and Depression Scale, Montreal Cognitive Assessment, dan Pittsburgh Sleep Quality Index. Secondary data is obtained through medical records. Analysis are performed to obtain the prevalence, relationship between PSF and associated factors, and correlation between FSS items with PSF.

Results: From 248 patients, the first 100 patients meeting the study criteria were taken as study subjects. The prevalence of PSF is 49%. In multivariate analysis, employment before stroke (aOR 0.34; 95%CI (0.11-0.99); p=0.047), number of comorbid (aOR 3.07; 95%CI (1.17-8.10); p=0.023), and thalamus (aOR 0.17; 95%CI (0.03-0.89); p=0.036) are associated with PSF. In the correlation test, the items from FSS that have the highest correlation to PSF are items 8 and 5.

Conclusion: In this study, nearly half of ischemic stroke patients experienced late PSF. Related factors need to be interpreted carefully. Fatigue is a subjective symptom so cultural and psychosocial factors needs to be considered."