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Ditemukan 2 dokumen yang sesuai dengan query
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Arry Yanuar, author
Molecular Docking Cytochrome P450 lsoform 2C9 with Phenytoin and Cimetidine (Poster Presentations) - Bandung International Conference on Medicinal Chemistry, 6-8 Agustus 2009
ABSTRACT Cytochrome P450 isoform 2C9 (CYP2C9) is a main enzyme which metabolizes phenytoin [I]. The inhibition of this enzyme will increase plasma level of phenytoin. Cimetidine is known as drug that inhibits this enzyme, resulting an increased plasma level of phenytoin [2]. Recently, the three dimentional molecular basis of interaction between...
2009
MK-Pdf
UI - Makalah dan Kertas Kerja  Universitas Indonesia Library
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Arry Yanuar, author
In Silica Analysis of Inhibition CYP3A4 by Nelfinavir using Molecular Docking Technique (Poster Presentations) - Bandung International Conference on Medicinal Chemistry, 6-8 Agustus 2009
Cytochrome P450 3A4 (CYP3A4) contributes to the metabolism of 50% of drugs used in therapy [l]. Nowadays, the structures of CYP3A4 are available through crystallography technique and these structures show that CYP3A4 has a flexible active site which allows many probabilities of ligand interaction [2]. Nelfinavir, one of the HIV-Protease...
Depok: Fakultas Farmasi Universitas Indonesia, 2009
MK-Pdf
UI - Makalah dan Kertas Kerja  Universitas Indonesia Library