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Ditemukan 6 dokumen yang sesuai dengan query
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Febiola Damayanti
Abstrak :
Pandemi COVID-19 (coronavirus disease 2019) membuat para peneliti di seluruh dunia bekerja untuk memahaminya dengan menerapkan pendekatan machine learning. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) merupakan penyebab dari COVID-19. Penelitian ini membahas klasifikaasi sekuens protein SARS-CoV-2 menggunakan metode LightGBM dan Elastic Net. Metode LightGBM merupakan metode gradient boosting yang cepat dan memiliki high-performance berbasis decision tree untuk melakukan prediksi. Total data sekuens protein yang digunakan adalah 2000 data yang diambil dari situs Uniprot. Uniprot merupakan salah satu situs yang digunakan terkait bioinformatika atau sumber daya sekuens protein dan informasi fungsional yang memiliki kualitas tinggi, komprehensif dan dapat diakses secara bebas. Data tersebut memiliki perincian yaitu 1000 data sekuens protein SARS-CoV-2 dan 1000 data sekuens protein bukan SARS-CoV-2. Python package Discere digunakan untuk mengekstraksi 27 fitur sekuens protein. Selanjutnya, Elastic Net digunakan untuk memilih fitur-fitur yang optimal dan terpilih sebanyak 10 fitur. Terakhir, LightGBM digunakan sebagai metode klasifikasi sekuens protein SARS-CoV-2. Hasil evaluasi performa LightGBM diukur dari akurasi, sensitivitas, dan spesifisitas. Nilai rata-rata akurasi diperoleh 98,87%, nilai rata-rata sensitivitas diperoleh 99,02%, dan nilai rata-rata spesifisitas diperoleh 98,82% ......The COVID-19 (coronavirus disease 2019) pandemic has researchers around the world working to understand it by applying a machine-learning approach. Secere acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the cause of COVID-19. This research discusses the classification of SARS-Cov-2 protein sequences using the LightGBM and Elastic Net methods. The LightGBM method is a gradient-boosting method that fast and has a high-performance decision tree based for making predictions. The total protein sequence data used is 2000 data taken from UniProt site. UniProt is one of the sites used for bioinformatics or protein sequence resources and functional information which is of high quality, comprehensive and freely accesible. The data has details, namely 1000 protein sequence data for SARS-CoV-2 and 1000 protein sequnce data for non-SARS-CoV-2. Python package Dsiscere is used to extraxt 27 protein sequence features. Futhermore, Elastic Net is used to select optimal features and 10 features are selected. While LightGBM is used as a classification method for SARS-Cov-2 protein sequences. The results of the LightGBM performance evaluation are measured by accuracy, sensitivity, and specificity. The average value for accuracy was 98,87%, the average value for sensitivity was 99,02%, and average value for specificity was 98,82%.
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2021
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UI - Skripsi Membership  Universitas Indonesia Library
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Timoshenko, Stephen P.
Tokyo: MCGraw-Hill Kogakusha, 1959
624.177 6 TIM t
Buku Teks  Universitas Indonesia Library
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Timoshenko, Stephen P.
Jakarta: Erlangga, 1988
624.177 6 TIM t
Buku Teks  Universitas Indonesia Library
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Mekhtiev, Magomed F.
Abstrak :
The book presents homogeneous solutions in static and dynamical problems of anisotropic theory of elasticity, which are constructed for a hollow cylinder. It also offers an asymptotic process for finding frequencies of natural vibrations of a hollow cylinder, and establishes a qualitative study of several applied theories of the boundaries of applicability. Further the authors develop a general theory for a transversally isotropic spherical shell, which includes methods for constructing inhomogeneous and homogeneous solutions that allow the characteristic features of the stress-strain state of an anisotropic spherical shell to be revealed. Lastly, the book introduces an asymptotic method for integrating the equations of anisotropic theory of elasticity in variable thickness plates and shells.
Singapore: Springer Nature, 2019
e20506880
eBooks  Universitas Indonesia Library
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Lagnese, John E.
Abstrak :
Presents one of the main directions of research in the area of design and analysis of feedback stabilizers for distributed parameter systems in structural dynamics. Important progress has been made in this area, driven, to a large extent, by problems in modern structural engineering that require active feedback control mechanisms to stabilize structures which may possess only very weak natural damping. Much of the progress is due to the development of new methods to analyze the stabilizing effects of specific feedback mechanisms. Boundary Stabilization of Thin Plates provides a comprehensive and unified treatment of asymptotic stability of a thin plate when appropriate stabilizing feedback mechanisms acting through forces and moments are introduced along a part of the edge of the plate. In particular, primary emphasis is placed on the derivation of explicit estimates of the asymptotic decay rate of the energy of the plate that are uniform with respect to the initial energy of the plate, that is, on uniform stabilization results. The method that is systematically employed throughout this book is the use of multipliers as the basis for the derivation of a priori asymptotic estimates on plate energy. It is only in recent years that the power of the multiplier method in the context of boundary stabilization of hyperbolic partial differential equations came to be realized. One of the more surprising applications of the method appears in Chapter 5, where it is used to derive asymptotic decay rates for the energy of the nonlinear von Karman plate, even though the technique is ostensibly a linear one.
Philadelphia: Society for Industrial and Applied Mathematics, 1989
e20451056
eBooks  Universitas Indonesia Library
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Takabatake, Hideo
Abstrak :
This book presents simplified analytical methodologies for static and dynamic problems concerning various elastic thin plates in the bending state and the potential effects of dead loads on static and dynamic behaviors. The plates considered vary in terms of the plane (e.g. rectangular or circular plane), stiffness of bending, transverse shear and mass. The representative examples include void slabs, plates stiffened with beams, stepped thickness plates, cellular plates and floating plates, in addition to normal plates. The closed-form approximate solutions are presented in connection with a groundbreaking methodology that can easily accommodate discontinuous variations in stiffness and mass with continuous function as for a distribution. The closed-form solutions can be used to determine the size of structural members in the preliminary design stages, and to predict potential problems with building slabs intended for human beings practical use.
Singapore: Springer Nature, 2019
e20509792
eBooks  Universitas Indonesia Library