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Hasil Pencarian

Ditemukan 7 dokumen yang sesuai dengan query
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Aqidatul Islamiyyati Elqowiyya, author
Optimasi deteksi gen mitochondrial large dan small subunit rRNA untuk mengidentifikasi Pneumocystis jirovecii pada pasien terkait tuberkulosis paru = Optimation of mitochondrial large and small subunit rRNA genes detection to identify Pneumocystis jirovecii in pulmonary tuberculosis-related patients
Identifikasi Pneumocystis jirovecii pada pasien dengan koinfeksi tuberkulosis (TB) paru masih menjadi tantangan karena gambaran klinis maupun radiologis keduanya yang mirip dan P. jirovecii tidak dapat dikultur. Identifikasi P. jirovecii di Indonesia masih berdasarkan pemeriksaan mikroskopik yang seringkali kurang sensitif. Oleh karena itu, dikembangkan teknik real time PCR yang lebih...
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
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UI - Tesis Membership  Universitas Indonesia Library
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Silmi Hanifah, author
Efek proteksi andrografolida terhadap kerusakan jantung tikus akibat doksorubisin melalui peningkatan fungsi mitokondria = Protective effect of andrographolide against doxorubicin-induced cardiotoxicity on rats through augmentation of mitochondrial function
Andrografolida telah terbukti memiliki efek kardioproteksi, namun masih belum diketahui mekanismenya. Penelitian ini bertujuan untuk melihat mekanisme dari andrografolida pada tikus dengan kardiotoksisitas doksorubisin, fokus pada biogenesis mitokondria. Tikus Sprague-Dawley jantan sebanyak 24 ekor dibagi secara acak menjadi empat kelompok: Normal (N); dosis kumulatif doksorubisin 16 mg/kgBB i.p. (Dox); Dox...
Depok: Fakultas Kedokteran Universitas Indonesia, 2022
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UI - Tesis Membership  Universitas Indonesia Library
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Drug-induced mitochondrial dysfunction / edited by James A. Dykens, Yvonne Will
This is the definitive, one-stop resource on preclinical drug evaluation for potential mitochondrial toxicity, addressing the issue upfront in the drug development process. It discusses mitochondrial impairment to organs, skeletal muscle, and nervous systems and details methodologies used to assess mitochondria function. It covers both in vitro and in vivo...
Hoboken: John Wiley & Sons, 2008
e20385370
eBooks  Universitas Indonesia Library
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Maryam Nazihah, author
Efek Ekstrak Etanol Buah Phaleria macrocarpa terhadap Penanda Kerusakan Mitokondria dan Profil Ekspresi Transporter Besi di Hati Tikus Model Hemosiderosis = Effect of Phaleria macrocarpa Fruit Ethanolic Extract on Mitochondrial Damage Marker and Iron Transporter Expressions Profile in the Liver of Hemosiderosis Rats
Mitokondria merupakan organel yang memetabolisme besi secara ekstensif, sehingga menjadi target kerusakan yang diinduksi besi pada kondisi hemosiderosis. Produksi reactive oxygen species (ROS) yang tinggi di mitokondria dapat lebih meningkat saat ada besi bebas yang kemudian memicu reaksi Fenton. Produksi ROS yang tinggi dapat menyebabkan stres oksidatif, sehingga regulasi konsentrasi...
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
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UI - Tesis Membership  Universitas Indonesia Library
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Roberto Scatena, editor
Advances in mitochondrial medicine
Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly...
Dordrecht: [, Springer], 2012
e20417543
eBooks  Universitas Indonesia Library
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Mitochondrial oxidative phosphorylation : nuclear-encoded genes, enzyme regulation, and pathophysiology / Bernhard Kadenbach, editor
This book will describe the nuclear encoded genes and their expressed proteins of mitochondrial oxidative phosphorylation. Most of these genes occur in eukaryotic cells, but not in bacteria or archaea...
New York: Springer, 2012
e20401596
eBooks  Universitas Indonesia Library
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Mitochondrial dysfunction in neurodegenerative disorders
As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as parkinson’s disease, alzheimer’s disease and multiple sclerosis and...
London : Springer, 2012
e20426197
eBooks  Universitas Indonesia Library