Hasil Pencarian  ::  Simpan CSV :: Kembali

Abstrak :
Comprehensive guide to clinical and surgical orthodontics for dental students. In depth coverage of diagnosis, treatment planning, materials, appliances and mechanics.

Abstrak :
Latar Belakang: Zoledronat merupakan jenis obat bisfosfonat yang paling kuat dalam menghambat resorpsi tulang. Zoledronat terbukti dapat menghambat pergerakan gigi ortodonti dan memperkuat penjangkaran maksimum, pada studi hewan. Sebagian besar studi masih menggunakan obat zoledronat dalam bentuk injeksi. Sediaan topikal mulai dikembangkan untuk mengatasi permasalahan yang ditimbulkan melalui pemberian obat secara injeksi Gel dan emulsi gel (emulgel) merupakan jenis sediaan obat topikal semi padat. Uji stabilitas suatu produk farmasi perlu dilakukan untuk menilai kemampuan suatu formulasi dalam mempertahankan sifat dan karakteristiknya saat pengemasan selama periode penyimpanan dan penggunaan. Penelitian ini bertujuan untuk membandingkan stabilitas fisik gel dan emulgel zoledronat yang disimpan pada suhu ruang (28±2°C) dan akselerasi (40°C) selama 8 minggu pengamatan. Metode penelitian: Gel dan emulgel disimpan selama 8 minggu pada suhu 28±2°C dan 40°C. Parameter stabilitas fisik yang dilihat antara lain organoleptis, pH, daya sebar, viskositas dan ukuran globul emulgel. Evaluasi dilakukan pada hari pertama, minggu ke-2,4,6 dan 8. Hasil: Terdapat perbedaan bermakna secara statistik pada seluruh parameter antar sediaan gel dan emulgel pada setiap waktu pengamatan. Pada sediaan emulgel yang disimpan di suhu 28±2°C, tidak terdapat perbedaan bermakna pada parameter viskositas, daya sebar dan ukuran globul selama 8 minggu pengamatan. Pada sediaan gel yang disimpan pada suhu 28±2°C, terdapat perbedaan bermakna pada seluruh parameter selama 8 minggu pengamatan. Kesimpulan: Emulgel zoledronat yang disimpan pada suhu 28±2°C selama 8 minggu stabil menurut semua parameter-parameter fisik yang diuji, kecuali pH. Perubahan pada nilai pH masih dekat dengan kisaran normal pH pada rongga mulut. Selain itu, gel zoledronat yang disimpan pada suhu 28±2°C selama 8 minggu dapat disimpulkan tidak stabil. ......Introduction: Zoledronate is the most potent bisphosphonate at inhibiting bone resorption. Zoledronate has been shown to inhibit orthodontic tooth movement and increase maximum anchorage in animal studies. Most studies are still using zoledronate in injectable form. The strategy to overcome problems associated with drug administration by injection is to develop zoledonate that can be administered topically. Gel and emulsion gel (emulgel) are a semi-solid drug preparation. Stability testing of pharmaceutical product must be done to evaluate the capability of a particular formulation to retain its properties and characteristics at the time of packaging throughout its period of storage and use. This study aims to compare the physical stability of zoledronat gel and emulgel stored in room temperature (28±2°C) and accelerated temperature (40°C) for eight weeks. Methods: Gel and emulgel were stored in room temperature (28±2°C) and accelerated temperature (40°C) for eight weeks. The physical stability parameters that were used in this study is organoleptic, pH, spreadability, viscosity and globule size diameter for emulgel preparation. Gel and emulgel were evaluated on the first day, 2nd week, 4th week, 6th week and 8th week. Results: There were statistically significant differences in all stability parameters, except pH, between gel and emulgel prepatations. For emulgel preparations that was stored in room temperature, there was no statistically significant differences in viscosity, spreadability and globule size diameter during eight weeks of observation. For gel preparations that was stored in room temperature, there were significant differences in all stability parameters during eight week of observation. Conclusion: According to the parameters in physical stability test, except pH, zoledronate emulgel stable in room temperature (28±2°C) storage for eight week observation. The changes in pH values was near from normal pH range in oral cavity. Other than that, zoledronate gel was not stable in room temperature (28±2°C) storage for eight week observation.

Abstrak :
With a concise, focused review of orthodontic concepts and current clinical information, including diagnosis, treatment planning, and clinical treatment, MOSBY'S ORTHODONTIC REVIEW is the resource you need to achieve the best results for success on competency examinations as well as excellent clinical outcomes. From foundational concepts to more subjective areas of treatment planning and clinical treatment, this book includes a wealth of information from distinguished educators, recent graduates, and practicing professionals to help you prepare for the NBDE, Part II and the ABO written and cl.

Abstrak :
ABSTRAK
Dalam masa perawatan ortodontik, kejadian lepasnya breket sering terjadi sehinggadiperlukan metode pembersihan yang cepat, efektif dan ekonomis. Hal terpenting adalahkarakter breket yang lepas setelah dibersihkan, kualitas tidak berubah sehingga dapatdipasang kembali. Penelitian ini bertujuan untuk mendapatkan sistem pelarut yang dapatmelepas bahan adesif dari basis breket metal berbasis solvolis tanpa mengubahkarakteristik breket metal dan lebih efektif dibandingkan metode yang umum digunakanyaitu sandblasting dan pembakaran. Penelusuran sistem pelarut melibatkan berbagaijenis pelarut dan faktor pendukungnya: termal, katalis dan surfaktan. Kinerja pelepasanbahan adesif dipantau dengan uji Shear Bond Strength SBS pada gigi Reused dan gigibaru, pengamatan topografi permukaan dan komposisi dengan Scanning ElectronMicroscopy SEM dan Electron Dispersive X-ray Spectroscopy EDAX sertagambaran sisa bahan adesif dengan Modifikasi Adhesive Remnant Index ARI .Spesimen penelitian terdiri atas tujuh puluh breket metal Stainless Steel Mini DynaLock dan seratus gigi Premolar satu dengan adesif Transbond XT. Hasil penelusurandiperoleh sistem pelarut dengan susunan pelarut organik N-Methyl-2-Pyrrolidone,katalis Zn Asetat, surfaktan Triton X-100 dan gelombang mikro. Uji Two Way Anovadari nilai SBS sandblasting, pembakaran dan solvolisis menunjukkan perbedaanbermakna p

---

ABSTRACT
During orthodontic treatment, the bracket loose often occurs so that a fast, effective andeconomical cleaning method is needed. The most important thing is the character of thecleaned bracket, the quality does not change so it can be reinserted. The objective of thisresearch is to find a solvent that can remove adhesive material from base metal bracketwithout changing the metal bracket characteristics and more effective than commonlyused method i.e. sandblasting and burning. The search for a solvent system involvesvarious types of solvents and their supporting factors thermal, catalyst and surfaceagent. The adhesive release was monitored by Shear Bond Strength SBS test onreused tooth and new tooth, surface topography observation and composition withScanning Electron Microscopy SEM and Electron Dispersive X Ray Spectroscopy EDAX as well as an overview of residual adhesive with Modified Adhesive RemnantIndex ARI . The study specimens consisted of seventy metal brackets of Stainless SteelMini Dyna Lock and one hundred first Premolar teeth with Transbond XT adhesives.The result of this research is the solvent system with organic solvent N Methyl 2 Pyrrolidone, catalyst Zn Acetate, surfactant Triton X 100 and microwave. Two wayAnova Test of SBS sandblasting, burning and solvolysis values showed significantdifferences p