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"Latar Belakang: Photoaging dapat mengakibatkan terjadinya penuaan kulit dini, kerutan kasar, hilangnya elastisitas dan kelenturan, tekstur kulit menjadi tidak rata, keratosis, serta perubahan pigmentasi kulit. Individu yang secara geografis tinggal di daerah sering terpajan sinar matahari lebih rentan mengalami photoaging, contohnya di area pesisir. Pengukuran photoaging menggunakan Skala Glogau, sedangkan pengukuran pajanan sinar matahari menggunakan sun index.Tujuan: Menganalisis profil photoaging berdasarkan skala Glogau dan korelasinya dengan riwayat pajanan matahari menggunakan sun index pada masyarakat pesisir.Metode: Merupakan studi deskriptif analitik dengan desain potong-lintang. Populasi target penelitian adalah orang berusia ≥20 tahun dengan kulit tipe Fitzpatrick III, IV, atau V, serta berisiko tinggi photoaging dengan rerata pajanan sinar matahari ≥ 3 jam perhari. Subjek penelitian (SP) diambil dengan metode consecutive sampling berdasarkan kriteria penerimaan dan penolakan. Analisis statistik dilakukan untuk membuktikan hipotesis penelitian. Nilai p<0,05 dianggap signifikan secara statistik. Hasil: Diantara 55 SP, 3 orang termasuk dalam Skala Glogau II, 42 orang dalam Skala Glogau III, dan 10 orang dalam Skala Glogau IV. Mayoritas memiliki kerutan yang tetap ada saat wajah tidak bergerak, paling banyak pada regio dahi 74,5%, nasolabial 70,9%, dan sudut mata 69,1%. Perubahan pigmentasi paling dominan ditemukan adaalah diskromnia (65,5%), serta tidak ditemukan keratosis aktinik pada mayoritas SP (98,2%). Diperoleh nilai median sun index sebesar 10,91, dan median BSA yang terpajan matahari sebesar 20,50%. Rerata total durasi pajanan matahari adalah 53,63 jam/minggu. Didapatkan korelasi lemah namun tidak bermakna secara statistik antara sun index dengan keparahan derajat photoaging berdasarkan Skala Glogau (r = 0,205; p = 0,134). Dari data tambahan didapatkan korelasi positif lemah yang bermakna antara lamanya pajanan matahari per minggu dan keparahan derajat photoaging berdasarkan Skala Glogau (r = 0,281; p = 0,038), serta didapatkan korelasi positif sedang yang bermakna antara usia dan derajat keparahan photoaging berdasarkan Skala Glogau (r = 0,631; p < 0,001). Didapatkan keratosis seboroik pada hampir seluruh SP, terutama pada kelompok Glogau tipe III (77,3%). Lebih banyak ditemukan SP yang tidak merokok pada Glogau II (100%) dan III (57,1%), sedangkan Glogau IV lebih banyak pada pasien merokok (80%). Didapatkan pula Glogau II dan III lebih banyak pada perempuan (100% dan 59,5%), sedangkan Glogau IV lebih banyak pada laki-laki (80%).Kesimpulan: Berdasarkan klasifikasi photoaging menurut Glogau, 3 orang termasuk dalam Skala Glogau II, 42 dalam Skala Glogau III, dan 10 dalam Skala Glogau IV. Tidak terdapat korelasi yang bermakna antara sun index dengan keparahan derajat photoaging berdasarkan Skala Glogau.......Background: Photoaging can cause premature skin aging, coarse wrinkles, loss of elasticity, uneven skin texture, keratosis, and skin pigmentation changes. Individuals who geographically live in areas frequently exposed to sunlight are more susceptible to photoaging, for example in coastal areas. Photoaging was classified using Glogau scale and sun exposure was measured by sun index.Aim: To analyze the photoaging profile based on Glogau Scale and its correlation with the history of sun exposure using sun index in coastal population.Method: This is an analytic descriptive study witha cross-sectional design. The target population for this study were people aged ≥20 years with skin types Fitzpatrick III, IV, or V, and at high risk of photoaging with an average sun exposure of ≥ 3 hours per day. The research subjects were taken by consecutive sampling method based on acceptance and rejection criteria. Appropriate statistical analysis was performed to prove the research hypothesis. P value of <0.05 is considered statistically significant.Results: Among 55 subjects, 3 people are included in the Glogau II cathegory, 42 people in the Glogau III, and 10 people in the Glogau IV. Majority have wrinkles at rest, the most wrinkles were found in forehead region 74.5%, nasolabial 70.9%, and crow’s feet 69.1%. The most dominant pigmentation changes were dyschromia (65.5%), and no actinic keratosis was found in the majority subjects (98.2%). The median sun index value was 10.91, and the BSA median exposed to the sun was 20.50%. The average total duration of sun exposure was 53.63 hours/week. In additional data, there a was weak correlation but not statically significant between sun index and the severity of photoaging based on the Glogau Scale (r = 0.205; p = 0.134). A significant weak correlation was obtained between sun exposure per week and the severity of photoaging based on the Glogau Scale (r = 0.281; p = 0.038), and a significant moderate correlation was obtained between age and the severity of photoaging based on the Glogau Scale (r = 0.631; p < 0.001). Seborrheic keratosis was found in almost all subjects, especially in the Glogau type III group (77.3%). There were more non-smokers in Glogau type II (100%) and III (57,1%), while type IV was more common in smoking patients (80%). It was also found that type II and III Glogau were more common in women (100% and 59,5%), while type IV Glogau were more common in men (80%).Conclusion: Based on Glogau photoaging scale, 3 people are included in the Glogau II category, 42 people in the Glogau III, and 10 people in the Glogau IV. There was no significant correlation between sun index and the severity of photoaging based on the Glogau Scale."

"Latar Belakang: Dermatitis seboroik (DS) merupakan kelainan inflamasi kronik pada area kulit yang kaya kelenjar sebasea. Hingga saat ini patogenesis DS terus berkembang, termasuk dikaitkan dengan kejadian sindrom metabolik. Oleh karena sindrom metabolik terjadi akibat resistensi insulin yang diperankan oleh jaringan lemak viseral, maka diduga kedua hal tersebut juga memiliki peran terhadap kejadian DS.Tujuan: mengetahui rerata HOMA-IR dan skala jaringan lemak viseral pada pasien DS, serta menilai perbedaannya dibandingkan dengan kontrol.Metode: Penelitian kasus-kontrol berpasangan ini dilakukan di Poliklinik Dermato-venereologi RSCM selama Juli-Agustus 2022. Kelompok kasus ialah pasien berusia ≥18 tahun, tidak hamil, IMT ≥18,5 kg/m2 yang terdiagnosis DS secara klinis, serta tidak memiliki penyakit imunokompromais, infeksi kronis, kanker, autoimun, atau degeneratif lainnya. Kelompok kontrol ialah pasien non-DS yang match berdasarkan usia, jenis kelamin, dan kategori IMT. Seluruh subjek menjalani pemeriksaan klinis, laboratorium, dan pengukuran skala lemak viseral menggunakan alat BIA TANITA® SC330.Hasil: Masing-masing kelompok DS dan kontrol berjumlah 36 subjek pada studi ini. Median(min-maks) usia kelompok DS ialah 26,5(20-45) tahun, jenis kelamin laki-laki 52,8%, dan median(min-maks) IMT sebesar 24,2(18,5-38,8) kg/m2. Median HOMA-IR ditemukan lebih tinggi pada kelompok DS dibandingkan kontrol (1,54[0,72-4,09] VS. 1,22[0,53-2,73]; p=0,031). Namun, tidak terdapat perbedaan yang bermakna secara statistik untuk skala lemak viseral antara kelompok DS dengan kontrol (6,5[1-14] VS. 6,0[1-12]; p=0,149).Kesimpulan: Nilai median HOMA-IR dan skala jaringan lemak viseral pada pasien DS adalah masing-masing 1,54 (IK95% 0,72-4,09) dan 6,5 (IK95% 1-14). Nilai HOMA-IR pada pasien DS lebih tinggi dibandingkan dengan kontrol dan bermakna secara statistik, tetapi tidak terdapat perbedaan bermakna secara statistik untuk skala lemak viseral.......Background: Seborrheic dermatitis (SD) is a chronic inflammatory disorder in sebaceous gland-rich skin. Until today the pathogenesis of SD continues to develop, including investigation about the link association between SD and metabolic syndrome. Metabolic syndrome is a disease caused by insulin resistance in which visceral fat tissue may play important role, therefore insulin resistance and visceral fat tissue are hypothesized to influence the development of SD.Objective: To measure the HOMA-IR and visceral fat rating scale in SD patients, and to investigate the differences compared to the control group.Methods: A matched case-control study was conducted in Dermatovenereology Clinic Cipto Mangunkusumo General Hospital in July-August 2022. Case group was non-pregnant patients aged ≥18 years old and BMI ≥18,5 kg/m2 which were clinically diagnosed with SD, and did not have any of immunocompromise, chronic infection, cancer, autoimmune, or degenerative disease. Control group was non-SD patients that were matched according to the age, gender, and BMI categories. All the subjects assigned for clinical and laboratory examination, and visceral fat measurement using BIA TANITA® SC330.This study involved 36 subjects in each SD and control group. Median(min-max) of age in SD group was 26.5(20-45) yo, male 52.8%, and median(min-max) of BMI was 24.2(18.5-38.8) kg/m2. Median HOMA-IR was significantly higher in SD group compared to the control group (1.54[0.72-4.09] VS. 1.22[0.53-2.73]; p=0.031). However, there was no significant difference for visceral fat rating scale between SD and control group (6.5[1-14] VS. 6.0[1-12]; p=0.149).Conclusion: The median HOMA-IR and visceral fat rating scale in SD were 1.54 (95%CI 0.72-4.09) and 6.5 (95%CI 1-14). HOMA-IR in SD group is higher to the control group and statistically significant, but there is no significant difference for visceral fat rating scale."