Hasil Pencarian  ::  Simpan CSV :: Kembali

"ABSTRAKLatar belakang. Di Sumatera Barat didapatkan peningkatan kasus infeksi virus dengue. Beberapa kasus juga terjadi pada bayi ≤ 1 tahun. Bayi mempunyai karakteristik klinik yang unik dan tidak banyak penelitian mengenai hal ini di Indonesia.Tujuan. Mengetahui profil klinis, laboratorium dan serologi infeksi virus dengue pada bayi yang di rawat di RSUP Dr. M Djamil Padang dari tahun 2012-2014Metode. Penelitian cross-sectional, menggunakan data rekam medic bayi IVD yang dirawat di RSUP Dr M Djamil Padang dari 1 Januari 2012-31 Desember 2014. Data yang dianalisis mencakup usia, jenis kelamin, hari demam saat diagnosis, suhu, demam, batuk, diare, muntah, kejang, hematemesis, melena, syok, ptekie, and hepatomegali.Hasil. 12 bayi digunakan sebagai sampel. Usia termuda bayi DBD adalah 3 bulan, dengan usia terbanyak 5 bulan (5 bayi). Muntah merupakan gejala tambahan yang paling banyak ditemukan (9 dari 12 bayi), diikuti oleh ptekie dan syok (masing-masing 6 bayi), serta batuk (5 bayi). 8 dari 12 bayi menunjukkan infeksi primerKesimpulan. Rerata usia dan kelompok usia terbanyak setara dengan penelitian sebelumnya.

---

ABSTRACTBackground. In West Sumatera, cases of dengue virus infection is increasing. Some occur in infants below 1 year old. Babies has unique clinical characteristic and only few researchs take place on this subject in Indonesia.Objection. Describing the clinical, laboratory, and serology profile of dengue virus infection in infants taken care at Dr. M Djamil Hospital in Padang, West Sumatera from 2012 to 2014.Methods. This is a cross-sectional study based on medical record data on baby who were treated in Dr M Djamil Padang from January 1st, 2012 to December 31st, 2014. The data analyzed were age, gender, fever duration at diagnosis, body temperature, fever, cough, diarrhea, vomit, seizure, hematemesis, melena, shock, ptekie, and hepatomegaly.Results. 12 babies were collected as sample. Youngest baby had DHF was 3 months old, while the oldest was 5 months old (5 infants). Vomit is the additional symptom most commonly found (9 of 12 infants), followed by ptekie and shock (6 babies each), and cough (5 infants). Eight of 12 infants showed primary infection.Conclusion. The mean for age and mode for age group were similar to previous studies"

"Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) merupakan coronavirus baru, pertama kali terdeteksi di Wuhan, Cina. Tingginya jumlah kasus dan cepatnya proses infeksi membutuhkan deteksi cepat dan akurat untuk menegakan diagnosis COVID-19. Studi bertujuan memperoleh sensitivitas dan spesifisitas uji serologi IgG SARS-CoV-2 Architect dibandingkan dan RT-PCR pada pasien COVID19. Studi ini menggunakan pendekatan potong lintang uji diagnostik, dengan menggunakan 128 pasien yang diperoleh di RSUP Persahabatan. Studi ini berlangsung sejak bulan April sampai Juli 2021 di RSUP Persahabatan. Sampel berupa swab nasofaring diambil dari pasien untuk diperiksa dengan uji RT PCR dan darah untuk uji serologi menggunakan Architect ® i2000SR Abbott. Hasil uji sensivitas Architect sebesar 27.37% (18.72%-37,48%) dan spesifisitas 63.64% (45,12% - 79,60%). NPV 23,33% dan PPV 68,42%. Kesimpulan: Secara keseluruhan uji serologi SARS-CoV-2 IgG Architech memiliki sensitivitas dan spesifisitas yang rendah dibanding dengan RTPCR. Architect dapat digunakan untuk screening, dapat digunakan pada fase akut, hasil negatif perlu dikonfirmasi dengan RT-PCR. Tidak ada hubungan antara Ct-value RTPCR dengan derajat keparahan COVID-19, dan terdapat hubungan antara titer Architect dengan derajat keparahan COVID-19. Tidak ada hubungan onset COVID-19 dengan hasil pemeriksaan RT-PCR dan Architect......Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a new coronavirus, which was first detected in Wuhan, China. The high number of cases and the rapid process of infection require fast and accurate detection to establish the diagnosis of COVID-19. The study aimed to obtain the sensitivity and specificity of the SARS-CoV2 Architect IgG serological test compared to RT-PCR in COVID-19 patients. This study used a cross-sectional approach to diagnostic testing, using 128 patients obtained from Persahabatan Hospital. This study took place from April 2021 to July 2021 at the Persahabatan Hospital. Nasopharyngeal swab samples were taken for RT-PCR and blood was drawn for serological testing using the Architect® i2000SR from Abbott. The sensitivity of Architect test was 27.37% (18.72–37.48%), specificity was 63.64% (45.12–79.60%), whereas NPV was 23.33% and PPV was 68.42%. Conclusion: Architech's SARS-CoV-2 IgG serological test has low sensitivity and specificity compared to RT-PCR. Architect can be used for screening, can be used in the acute phase, negative results need to be confirmed by RT-PCR. There is no relationship between the Ct-value RT-PCR and the severity of COVID-19, and there is a relationship between Architect titers and the severity of COVID-19. There is no relationship between the onset of COVID-19 and the results of the RT-PCR and Architect examinations."

"Rotavirus causes 25?55% of all hospital admissions for diarrhea and approximately 611.000 deaths every year in developing countries. Clinically, it is not possible to recognize the diarrhea caused by rotavirus and other infections. To know a causative agent of rotavirus gastroenteritis, availability of an accurate diagnosis assay is necessary. Therefore, we developed real time RT-PCR assay (rRT-PCR) assay for confirmation of infections of Group A or C rotaviruses simultaneously. A total of 54 stool samples obtained from pediatric patients (< 5 years old) was used in this study. Allsamples were tested for Group A rotavirus by Serological rapid test. Result of serological rapid test was compared with rRT-PCR assay to obtain the test accuracies of both assays. Result of this study showed that rates of positive testing for Group A rotavirus by serological rapid test and the rRT-PCR assay were 22.22% and 18.50%, espectively. Forty-two serology-negative specimens for Group A rotavirus were also PCR negative (100% specificity). Two serology-positive specimens for Group A rotavirus was rRT-PCR negative (confirmed by electrophoresis gel); therefore, rRT-PCR assayrepresents the decrease of 3.70% in the number of specimens that are positive for Group A rotavirus. For Group C rotavirus, all tested samples were no rRT-PCR positive and the results need to be confirmed in the future. "

"ABSTRAKLatar belakang: Frambusia atau yaws merupakan penyakit akibat infeksi Treponema pallidum subspecies pertenue yang menahun dan terutama mengenai kulit serta tulang. Penegakkan diagnosis berdasarkan klinis dan serologis. Program temuan kasus frambusia didasarkan atas temuan klinis menurut World Health Organization WHO , kemungkinan terdapat frambusia tanpa lesi klinis yang tidak terdiagnosis masih belum dapat disingkirkan. Belum ada penelitian proporsi di suatu desa yang dinyatakan endemis. Tujuan: Mengetahui proporsi kasus frambusia berdasarkan kriteria klinis WHO dan pemeriksaan serologis di desa Sei Berombang pada anak usia 1-12 tahun periode 22-27 Agustus 2016. Metode: Studi potong lintang ini dilakukan pada tanggal 22-27 Agustus 2016 di desa Sei Berombang, Sumatera Utara. Pemilihan sampel dilakukan secara consecutive sampling. Subjek kemudian dilakukan anamnesis, pemeriksaan fisis, dan pemeriksaan rapid diagnostic test RDT . Hasil : Didapatkan total 129 subjek dengan median usia 9 tahun termuda 1 tahun dan tertua 12 tahun . Sebanyak 14 anak dengan lesi klinis suspek frambusia, sedangkan 4 anak dengan RDT yang positif. Hanya 3 anak dari RDT yang positif memiliki temuan klinis. Lesi klinis suspek frambusia yang paling banyak ditemukan adalah makula hipopigmentasi dan skar atrofik, sedangkan lokasi tersering adalah tungkai bawah. Simpulan: Ditemukan proporsi suspek frambusia berdasarkan klinis adalah 10,85 , sedangkan proporsi frambusia konfirmasi berdasarkan klinis dan serologis adalah 2,33 . Dua subjek didiagnosis frambusia laten, sedangkan satu subjek didiagnosis sebagai frambusia primer. Kata kunci: frambusia, proporsi, anak

---

ABSTRACTBackground Yaws is a chronic infectious disease caused by Treponema pallidum subspecies pertenue, mainly affecting skin and bone. Diagnosis of yaws is based on clinical manifestation and serologic test. According to WHO, yaws detection program is focused on clinical manifestation. Thus, it is possible that latent yaws without any clinical manifestation is still under diagnosed. Until recently, there is no proportion study performed in remote endemic village.Objective To determine the proportion of yaws based on WHO clinical criteria and serologic test in children age 1 12 years old in Sei Berombang village.Methods This cross sectional study was conducted on 22nd 27th August 2016 in Sei Berombang village, North Sumatra. We recruited the subjects consecutively and performed anamnesis, clinical examination, and rapid diagnostic test RDT .Results A total of 129 subjects were examined with median age of 9 years old 1 12 years old . Yaws was suspected in 14 subjects, but only 4 subjects were reactive to RDT. Three subjects had clinical manifestation and RDT reactive. Hypopigmentation patch and atrophic scar were the most common clinical findings in this study. Most lesions were found in lower extremities. Conclusion Proportion of suspected yaws based on clinical manifestation is 10,85 in this study. Proportion of confirmed yaws based on clinical manifestation and serology is 2,33 . Two subjects diagnosed with latent yaws and one subject was diagnosed with primary yaws. "

"his classic resource offers the current, comprehensive coverage of immunology you need to stay on the cutting-edge of clinical laboratory science. It provides a solid foundation of knowledge and skills to take you from basic immunologic mechanisms and serologic concepts to the theory behind the procedures you'll perform in the lab, including automated techniques. It also explores the medical applications of clinical laboratory science, with information on disorders of infectious and immunologic origin, as well as topics such as transplantation and tumor immunology. Learning objectives, review questions, step-by-step procedures, and case studies help you master key concepts and prepare you to succeed in today's modern laboratory environment."