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Hasil Pencarian

Ditemukan 5 dokumen yang sesuai dengan query
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Samosir, David R. S.
"Based on its relation to the liver sinusoid, increased pressure of portal vein can occur at three levels: presinusoid, sinusoid ,and postsinusoid. Obstruction of the presinusoid veins can be caused by extra-hepatic condition such as venous thrombosis.
We reported a case of portal hypertension with esophageal varices bleeding was a result of obstruction due to thrombosis of the splenic vein and portal vein under hypercoagulant conditions due to thrombocyto-sis. The management of esophageal varices was sclerotherapy while for overcome the thrombosis the patient was given hydroxy urea.
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The Indonesia Journal of Gastroenterology Hepatology and Digestive Endoscopy, 2002
IJGH-3-1-April2002-24
Artikel Jurnal  Universitas Indonesia Library
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Siahaan, Billy Stinggo Paskharan
"Latar Belakang: Pecahnya varises esofagus (EV) tetap menjadi salah satu komplikasi sirosis yang paling parah. Sebagai gold standard untuk memprediksi kecelakaan ini, Esophagogastroduodenoscopy (EGD) sendiri juga memiliki kelemahan. Tidak semua pasien nyaman dan mau menerima modalitas ini dalam praktik klinis terlepas dari risiko dan beban biaya. Oleh karena itu, pencarian modalitas noninvasif lain yang nyaman tetapi dengan akurasi tinggi masih perlu dipelajari. Diantaranya, Pengukuran Kekakuan Limpa (SSM), Pengukuran Kekakuan Hati (LSM), dan skor Aspartate Amino Transferase to Platelet Ratio Index (APRI) menjadi populer dan dipelajari secara intensif di banyak pusat dengan akurasi yang baik, tetapi hasilnya tetap bertentangan di beberapa penelitian.

Tujuan : Mengetahui kinerja skor SSM, LSM, APRI, dan kombinasinya untuk memprediksi EV pada pasien sirosis hati.

Metode : Sebanyak 141 pasien sirosis hati yang menjalani endoskopi, SSM, LSM, dan perhitungan skor APRI antara Januari 2023 dan Maret 2023. Analisa diagnostik dinilai menggunakan area di bawah kurva penerima-operator (AUC) untuk mengukur dan membandingkan kinerja setiap pengukuran dan kombinasi untuk memprediksi EV dan untuk mendapatkan nilai prediksi optimal yang sesuai. Pengukuran elastografi transien (TE) dilakukan menggunakan fibroscan khusus limpa dengan probe 100 hz.

 

Hasil : Dari 141 pasien, etiologi terbanyak adalah hepatitis B sebanyak 71 pasien (50,4%). Varises esofagus ditemukan pada 116 pasien (86,3%). Dengan menggunakan area under receiver, SSM pada titik potong 40,1 kPa memiliki kinerja terbaik untuk memprediksi EV pada sirosis dengan AUC 0,892 (sensitivitas 88,79%, spesifisitas 80%), diikuti oleh LSM pada titik potong  10,2 kPa dengan AUC 0,832 (sensitivitas 90,52%, spesifisitas 60%), dan skor APRI pada titik potong 0,72 memiliki AUC terendah antara lain 0,780 (sensitivitas 77,59%, spesifisitas 80%). Kombinasi ketiga pemerikssan tidak menunjukkan performa yang lebih baik dibandingkan SSM secara tunggal dengan AUC 0,892.

 

Kesimpulan : SSM memberikan kinerja yang lebih baik daripada skor LSM dan APRI untuk memprediksi EV.


Background: Esophageal varices (EV) rupture remains one of the most severe complications of cirrhosis. As a gold standard to predict this accident, Esophagogastroduodenoscopy (EGD) itself also has a weakness. Not all patients are convenient and willing to accept this modality in clinical practice apart from the risk and cost burden. Hence, the search for other noninvasive modalities that are convenient but with high accuracy is still noteworthy to be studied. Among them, Spleen Stiffness Measurement (SSM), Liver Stiffness Measurement (LSM), and the Aspartate Amino Transferase to Platelet Ratio Index (APRI) score become popular and intensively studied in many centers with good accuracy, but the results remain conflicting in some studies.

 

Objective: To investigate the performance of SSM, LSM, APRI score, and their combination for predicting EV in liver cirrhosis patients.

 

Methods: A total of 141 patients with liver cirrhosis who had undergone endoscopy, SSM, LSM, and APRI score calculation between January 2023 and March 2023 were enrolled. Diagnostic applicability was assessed by the area under the receiver-operator curve (AUC) to measure and compare the performance of each measurement and combination for predicting EV and to obtain the corresponding optimal prediction value. Transient elastography (TE) measurement was done using spleen-dedicated fibroscan with a 100 Hz probe.

 

Results: Of the 141 patients, the most common etiology was hepatitis B 71 patients (50,4%). Esophageal varices were found in 116 patients (86,3%). Using area under receiver, SSM at cut-off 40,1 kPa had the best performance for predicting EV in cirrhosis with AUC 0,892 (sensitivity 88,79%, specificity 80%), followed by LSM at cut-off 10,2 kPa with AUC 0,832 (sensitivity 90,52%, specificity 60%), and APRI score at cut-off 0,72 had the lowest AUC among others 0,780 (sensitivity 77,59%, specificity 80%). The combination of all measurement tools did not show better performance than SSM alone with AUC 0,892.

 

Conclusion: SSM provides better performance than LSM and APRI score for predicting EV"

Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
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UI - Tugas Akhir  Universitas Indonesia Library
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Dogma Handal
"Pendahuluan. Esofagektomi merupakan tata laksana pembedahan standar bagi pasien kanker esofagus resektabel. Namun, angka kesembuhan tindakan ini hanya berkisar antara 25 - 35% dan dihubungkan dengan seriusnya risiko komplikasi pascabedah. Pasien pascaesofagektomi diketahui mengalami penurunan kualitas hidup, tetapi belum ada penelitiannya di Indonesia. Penelitian ini dilakukan untuk mengetahui kualitas hidup pasien pascaesofagektomi pada populasi pasien di RSUPN Dr. Cipto Mangunkusumo (RSCM).
Metode. Penelitian ini merupakan kohort retrospektif dengan menggunakan instrumen yang dikeluarkan oleh European Organization for Research and Treatment of Cancer (EORTC), yaitu modul khusus kanker esofagus EORTC-QLQ-OES18 dan core questionnaire C30. Populasinya adalah pasien pascaesofagektomi periode 2015—2021 di RSCM.
Hasil. Sebanyak 35 subjek dilakukan esofagektomi dan rekonstruksi pascaesofagektomi. Terdiri dari laki-laki 62,9% dan perempuan 37,1%. Rerata usia adalah 43,8 tahun (SB: 13,1). Median kualitas hidup (global health) dari semua subjek adalah 83,3 (IQR: 25,0). Item pertanyaan skala fungsional terhadap keseluruhan subjek yang memiliki skor paling rendah adalah cognitive functioning (CF). Sedangkan berdasarkan item pertanyaan skala gejala terhadap keseluruhan subjek yang memiliki skor paling tinggi, yaitu nausea and vomiting (NV), pain (PA), dysphagia (OESDYS), eating (OESEAT), choking (OESCH), dan coughing (OESCO).
Kesimpulan. Kualitas hidup pasien pascaesofagektomi di RSCM berdasarkan kuesioner EORTC-QLQ-C30 dan OES18 secara keseluruhan tergolong baik. Faktor prognostik yang berhubungan dengan penurunan kualitas hidup sebaiknya lebih diedukasi ke pasien dan dilakukan upaya persiapan sejak sebelum tindakan esofagektomi dikerjakan sehingga dapat memaksimalkan kualitas hidup pascaoperasi.

Introduction. Esophagectomy is the standard surgical treatment for resectable esophageal cancer patients. However, the success rate for this procedure was about 25—35% and was associated with a severe risk of postoperative complications. Patients after esophagectomy have decreased their quality of life (QOL), but no research has been done in Indonesia. This study was conducted to determine the quality of life after esophagectomy in Indonesia based on the patient population at Dr. Cipto Mangunkusumo General Hospital (CMGH).
Method. A retrospective study was conducted using quality of life instruments issued by the European Organization for Research and Treatment of Cancer (EORTC). It consists of the module for esophageal cancer EORTC-QLQ-OES18 and the core questionnaire C30. Subjects were patients after esophagectomy in 2015—2021 at CMGH.
Results. About 35 subjects underwent esophagectomy and followed by reconstruction, which comprised 62.9% male and 37.1% female. The mean age was 43.8 years (SD: 13.1 years). All subjects' median global health was 83.3 (IQR: 25.0). The overall functional scale question item with the lowest score was cognitive functioning (CF) 66.7 (IQR: 50.0). Meanwhile, based on the question items on the overall symptom scale, the worst scores were nausea and vomiting (NV) 16.7 (IQR: 50.0), pain (PA) 16.7 (IQR: 33.3), dysphagia (OESDYS) 33.3 (IQR: 33.3), eating (OESEAT) 34.5 (IQR: 23.9), choking (OESCH) 33.3 (IQR: 33.3), and coughing (OESCO) 33.3 (IQR: 33.3).
Conclusion. The overall QOL after esophagectomy at CMGH based on the EORTC-QLQ-C30 and OES18 questionnaires was good. Prognostic factors associated with decreased quality of life should be better educated to patients and prepared well before the esophagectomy procedure, thus maximizing quality of life after esophagectomy.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2022
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UI - Tesis Membership  Universitas Indonesia Library
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Siti Komariyah
"Striktur esofagus adalah penyempitan lumen esophagus akibat inflamasi dan nekrosis. Laparotomy feeding jejunostomy yaitu prosedur bedah umum yang dilakukan untuk pasien yang tidak dapat makan secara oral sampai dengan operasi definitif. Nyeri merupakan efek dari pembedahan. Teknik relaksasi merupakan metode untuk mengurangi tekanan terkait dengan rasa nyeri. Tujuan karya tulis ini untuk menganalisis kegiatan pemberian intervensi teknik relaksasi: nafas dalam pada Ny. RA dengan striktur esofagus post laparatomy feeding jejunostomy. Teknik relaksasi merupakan teknik untuk mengurangi rasa nyeri dengan menggunakan pernapasan yang lambat dan berirama. Skrining dan evaluasi nyeri mengunakan Nurmeric Rating Scale. Latihan relaksasi diberikan sehari sekali selama 5 menit dalam 3 hari. Hasil dari karya ilmiah ini menunjukan adanya penurunan skor nyeri yang dinilai dengan Numeric Rating Scale. Skor NRS sebelum dilakukan intervensi adalah 5 dan NRS setelah dilakukan intervensi menjadi 2. Karya ilmiah ini diharapkan dapat digunakan menjadi salah satu dasar untuk dijadikan panduan dalam pembuatan Standar Prosedur Operasional latihan relaksasi untuk pasien post laparotomy feeding jejunostomy

Esophageal stricture is a narrowing of the lumen of the esophagus due to inflammation and necrosis. Laparotomy feeding jejunostomy is a common surgical procedure performed for patients who cannot eat orally until definitive surgery. Pain is an effect of surgery. Relaxation techniques are methods to reduce the pressure associated with pain. The purpose of this paper is to analyze the activity of providing relaxation technique interventions: deep breathing to Ny. RA with esophageal stricture post laparotomy feeding jejunostomy. Relaxation technique is a technique to reduce pain by using slow and rhythmic breathing. Screening and evaluation of pain using the Nurmeric Rating Scale. Relaxation exercises are given once a day for 5 minutes for 3 days. The results of this scientific work show a decrease in pain scores as assessed by the Numeric Rating Scale. The NRS score before the intervention was 5 and the NRS after the intervention was 2. This scientific work is expected to be used as a basis to be used as a guide in making Standard Operating Procedures for relaxation exercises for post-laparotomy feeding jejunostomy patients."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2022
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UI - Tugas Akhir  Universitas Indonesia Library
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"Assessment of surgical innovation is complex. This is especially true in esophageal surgery owing to difficulties in interpreting pathophysiology, staging malignant tumors with accuracy, and standardizing and tailoring the available surgical procedures to the individual patient. This book introduces the general and the thoracic surgeon to the latest developments in esophageal surgery; in each chapter the reader will find a concise background analysis of the topic in question and a state of the art review of diagnosis and treatment. The indications for surgery and the rationale for use of an innovative technique or technology are discussed in detail. Challenging and provocative questions and comments by selected panelists complement each chapter, enhancing the quality of information. Innovation in Esophageal Surgery will be highly informative for both the novice and the expert surgeon wishing to enter the arena of esophageal surgery.
A multidisciplinary team of experts offers an evidence-based approach and critical analysis: endoscopic, surgical, and hybrid surgical techniques that will soon change the approach to esophageal disease are described in detail."
Milan: Springer, 2012
e20426475
eBooks  Universitas Indonesia Library