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"Telah dilakukan penelitian pendahuluan pola kepekaan kuman terhadap antibiotika di ruang rawat intensif rumah sakit Fatmawati Jakarta, secara restrospektif terhadap data sekunder hasil uji kepekaan antinbiotika dan jenis kuman dari 205 pasien dalam kurun waktu 2001-2002. hasil menunjukkan jenis kuman patogen adaah Psedonoman sp. Klebsiella sp. Escherichia coli, Streptococcus haemolyticus. Staphylococcus aureus. Pola kepekaannya menunjukkn bahwa kuman patogen mempunyai resistensi tertinggi terhadap ampisilin, amoksisilin penisilin G, tetrasiklin dan kloramfenikol, Kepekaan tertinggi ditujunjkkan oleh fosmisin, amikasin, seftriakson pada Pseudomonas sp. netilmihn, amikasin, sefriakson pada Klebsiella sp seftriakson, amikasin, sferizoksim pada Eschericha coliThe Sensitivity Pattern of Microorganisms against Antibiotics at the Intensive Care Unit of Fatmawati HospitalJakarta 2001 – 2002. A preliminary study was conducted on the sensitivity pattern of microorganisms againstantibiotics at the intensive care unit of Fatmawati Hospital Jakarta. Retrospective, secondary data were collected onresults of antibiotics sensitivity tests and kind of microorganisms of 205 patients during the years 2001 – 2002.Pathogenic species found were Pseudomonas sp. Klebsiella sp. Escherichia coli, Streptococcus β haemolyticus,Staphylococcus epidermidis and Staphylococcus aureus. The pattern of resistance showed that pathogenicmicroorganisms were most resistant agains ampicillin, amoxycillin, penicillin G, tetracycline and chloramphenicol. Thehighest sensitivity levels were shown by fosmicin, amikacin, ceftriaxone to Pseudomonas sp. netilmicin, amikacin,ceftriaxone to Klebsiella sp. ceftriaxone, amikacin, ceftizoxime to Escherichia coli."

"Telah dilakukan penelitian terhadap faktor yang mempengaruhi ketidak sesuaian penggunaan antibiotika dengan uji kepekaan di ruang rawat intensif rumah sakit Fatmawati Jakarta dengan suatu desain penelitian kasus kontrol, dimana kasus adalah pasien yang causa penyakitnya resisten terhadap suatu antibiotika, menggunakan antibiotika tersebut dalam terapi. Kontrol adalah pasien yang causa penyakitnya resisten terhadap suatu antibiotika tetapi penggunaan antibiotika lain yang efektif. Subjek penelitian yang diperoleh adalah 34 kasus dan 41 kontrol. Faktor yang mempengaruhi antibiotika tidak efektif adalah pekerjaan pasien (rasio odds = 0.25 dan 95% CI 0.09-0.71). Jika dibandingkan dengan pasien yang tidak bekerja, maka yang bekerja mempunyai risiko 75% lebih rendah dalam hal penggunaan antibiotika yang tidak efektif.Several Factors Influencing Irrational Antibiotics Treatments in Intensive Care Unit at Fatmawati HospitalJakarta 2001 – 2002. A study was conducted in the intensive care unit at Fatmawati Hospital, Jakarta, concerning afactor influencing the inappropriate use of antibiotics, proven by the resistance against a certain antibiotic, however thisantibiotic was used for therapy. Cases in the control group were resistant cases against an antibiotic and therefore weregiven another antibiotic, against which the patients were sensitive. A total of 34 cases were selected as researchsubjects, whereas 41 cases were included in the control group. The factor influencing the use of antibiotics againstwhich patient were resistant was “having a job of the patient” (odds ratio = 0,25 and 95 % CI 0,09 – 0,71). Incomparison the group of patients with a job with the group without a job: the group with a job had a 75 % lower risk inusing ineffective antibiotics."

"Purpose: We evaluated cultured specimens from silicone tubes removed from patients with congenital nasolacrimal duct obstruction and determined the antibiotic sensitives of the specimens.Methods: This study included 26 eyes of 22 patients who had received endonasal silicone tube intubation for congenital nasolacrimal duct obstruction. The removed silicone tubes were divided into canalicus, lacrimal sac, nasolacrimal duct and nasal cavity parts according to insertion state. Then, bacteria and fungus cultures were performed and rheir antibiotic sensitivity was tested. Results: Bacteria culture rate was 80.8% in the canaliculus and the lacrimal sac, and 88.5% in the lacrimal duct, and the nasal cavity, which was not significantly higher in the nasal cavity than in the nasolacrimal duct and in the nasolacrimal duct than in the lacrimal sac and the canaliculus (p-value < 0.05). The species of cultured Gram-positive bacteria were in the following order: Staphylococcus aureus, streptococcus pneumonia and coagulase negative staphylococcus. Common species of cultured Gram-negative bacteria were Pseudomonas and Serratia marcescenes. All six species of cultured fungi were candida. Among 12 Staphylococcus aureus cultured, eight species showd resistance to methicillin (MRSA). In all patients, the symptomps and the signs of nasolacrimal duct obstruction improved after the tube removal. Conclusions: Bacterial and fungal infection of the silicone tube in patients with congenital nasolacrimal duct obstruction does not appear to affect directly the outcome of silicone tube intubation. Further studies of bacterium and fungi in the nasolacrimal duct before silicone tube intubation are needed for determining the infection causing nasolacarimal duct obstruction J Korean Ophthalmol Soc 2014;55(8): 1121-1125"

"Latar Belakang: Telah dilakukan penelitian dengan tujuan mengetahui gambaran klinis dan mikrobiologis penderita infeksi kaki diabetik derajat 3 dan 4 sesuai klasifikasi PEDIS. Penelitian prospektif terakhir pada ulkus/gangren kaki diabetik di RSCM dilakukan tahun 1984. Bahan dan Metode: Penelitian dilakukan prospektif potong-lintang di RSCM pada bulan Maret-Desember 2004 dan didapatkan 52 penderita infeksi kaki diabetik yang memenuhi kriteria inklusi. Gambaran klinis penderita meliputi luka (Iokal) maupun sistemik sesuai klasifikasi PEDIS (Perfusion, Extent, DeptMissue lose, Infection, Sensation), ditambah modifikasinya (bau luka dan krepitasilgas). Pemeriksaan mikrobiologis infeksi kaki diabetik dilakukan biakan kuman aeroblanaerob dan tes kepekaan antibiotik.

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Background. This study aimed to recognize clinical pictures and microbiological pattern in 3rd and 4th degrees of the PEDIS classification of diabetic foot infection (OFI). The last prospective study on diabetic ulcer/gangrene in RSCM was conducted in 1984. Materials and Methods. The design was a prospective cross sectional study conducted in RSCM from March till December 2004. There were 52 OFl's patients fulfilled the inclusion criteria. The clinical pictures were included local wounds and systemic manifestations according to the PEDIS classification with additional modification (the wound's odour and crepitation/gas). Microbiological examination were done culture for aerobic/anaerobic microorganisms and the antibiotics sensitivity test."