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Abstrak :
This book is a primer for translational vascular medicine and discusses the evolving and exciting areas of basic science applied to vascular medicine. The book is based on the third vascular biology conference held at The Royal College of Physicians in 2008. It provides a large amount of new basic and clinical information and the contributors are world leaders.

Abstrak :
ABSTRAK
Untuk menentukan variabel prediktor terhadap ketahanan hidup penderita pascainfark dilakukan penelitian secara retrospektif terhadap 174 orang penderita yang dirawat di RSJHK dalam periode 1 Januari 1986 sampai dengan 31 Desember 1987. Pengamatan penderita dilakukan sampai tanggal 28 Februari 1989.

Sebanyak 16 variabel diuji secara univariat dengan uji Log-Rank dan selanjutnya dengan 'Step-wise variable selection' untuk analisis multivariat. Terbukti secara bermakna 5 variabel yang mempengaruhi angka ketahanan hidup yaitu: jenis kelamin (X2 = 15,70; p < 0,00), riwayat infark terdahulu (X2 = 6,55; p < 0,025), riwayat penyakit diabetes mellitus (X2 = 7,82; p t 0,01), riwayat gagal jantung selama perawatan (X2 = 14,58; p < 0,005) dan adanya blok cabang berkas kanan His (X2=15,29; p< 0,005). Dan 4 diantaranya, kecuali riwayat penyakit DM merupakan faktor rediktor yang independen

Angka ketahanan hidup secara keseluruhan yang diperoleh dengan cara Kaplan Meir adalah sebesar 89,6 ± 2,36 % selama pengamatan 3 tahun. Diperlukan tindakan yang agresif terhadap penderita dengan faktor-faktor tersebut untuk memperbaiki ketahanan hidup penderita pascainfark berikut kualitas hidupnya.

Abstrak :
A concise summary of the most important medical and scientific topics concerning cardiovascular medicine in the primary care environment, this new edition of Cardiology in family practice has been updated with cutting-edge information and useful tips. Written in an easy-to-read format (background, diagnosis and disease management) and emphasizing practical techniques for evaluation and treatment, the authors explain the basic mechanisms underlying cardiovascular disease states and the treatment strategies that arise from them. Topics include stable angina, acute coronary syndromes, arrythmias, hypertension, pericardial and valvular diseases, and hyperlipidemia. New figures have been added to each chapter in this edition.

Abstrak :
The human cardiovascular and respiratory control systems represent an important focal point for developing physiological control theory because of the complexity of the control mechanisms involved, the interaction between cardiovascular and respiratory function, and the importance of this interaction in many clinical situations. This volume brings together the range of control processes involved in the effective regulation of these systems and develops modeling themes, strategies, and key clinical applications using contemporary mathematical and control methodologies. The reader will gain an appreciation of how analytical techniques and ideas from optimal control theory, systems theory, and numerical analysis can be utilized to better understand the regulation processes in human cardiovascular and respiratory systems. Cardiovascular and Respiratory Systems: Modeling, Analysis, and Control uses a principle-based modeling approach and analysis of feedback control regulation to elucidate the physiological relationships. Models are arranged around specific questions or conditions, such as exercise or sleep transition, and are generally based on physiological mechanisms rather than on formal descriptions of input-output behavior. The authors ask open questions relevant to medical and clinical applications and clarify underlying themes of physiological control organization. Current problems, key issues, developing trends, and unresolved questions are highlighted.

Abstrak :
ABSTRAK
Tujuan penelitian ini untuk menilai, apakah tolok ukur prabedah yang selama ini dipergunakan untuk memperkirakan keberhasilan tindakan bedah ganti katup aorta di RSJHK sudah cukup memadai. Penelitian bersifat studi retrospektif terhadap semua penderita Regurgitasi Aorta yang dilakukan penggantian katup aorta di Rumah Sakit Jantung Harapan Kita Jakarta pada periode Februari 1986 s.d. 31 Desember 1989.

Terdapat 31 penderita yang memenuhi kriteria penelitian, terdiri atas 9 penderita wanita dan 22 pria,umur berkisar antara 10-60 tahun, rata rata 33,77±14,58 tahun.

Empat belas variabel prabedah dan tiga variabel intrabedah .diteliti untuk melihat pengaruhnya terhadap kematian bedah dan perbaikan kelas fungsionalnya (NYHA) pascabedah. Dari hasil tindakan bedah penderita dikelompokkan dalam dua kelompok yaitu kelompok A (hasil kurang baik) dan kelompok B (hasil baik). Kelompok A penderita yang mengalami kematian bedah atau penderita dengan kelas fungsional menetap atau bahkan memburuk (n : B). Kelompok B penderita yang hidup dan kelas fungsionalnya meningkat satu tingkat atau lebih dinilai secara kriteria NYHP (n : 23).

Angka kematian bedah 16.12%. Dari 14 variabel prabedah tidak didapatkan perbedaan yang bermakna dari kelompok A dan kelompok B, dari 3 variabel intrabedah terdapat satu variabel yang berbeda bermakna yaitu lama klem aorta.

Kelompok A dengan rata rata 185±221,56 menit dan kelompok B 80,69±22,01 menit ( p:0.03 ).

Sebagai kesimpulan penelitian ini belum dapat mencari variabel prabedah mana yang berpengaruh terhadap kematian bedah ,pada tindakan bedah ganti katup aorta pada penderita Regurgitasi Aorta. Dengan tolok ukur yang lama tampaknya seleksi penderita prabedah sudah cukup ketat oleh karena nilai dari rata-rata tolok ukur dibawah nilai risiko tinggi yang dianjurkan peneliti sebelumnya.

Suatu penelitian prospektif dan jangka panjang perlu dilakukan agar dapat dicari variabel prognostiknya dan angka ketahanan hidup dari penderita Regurgitasi Aorta pascabedah ganti katup aorta di Rumah Sakit Jantung Harapan Kita Jakarta.

Abstrak :
Clinical cardiac MRI is a comprehensive textbook intended for everyone involved in magnetic resonance imaging of the heart. It is designed both as a useful guide for newcomers to the field and as an aid for those who routinely perform such studies. Providing theoretical background information, this illustrated volume examines imaging acquisition and potential pitfalls. It presents guidelines on the interpretation of clinical data in a range of cardiac pathology that can be encountered. In this second edition, the aim has been to maintain the same quality while incorporating the newest insights and developments in this rapidly evolving domain of medical imaging. Finally, the selection of 100 real-life cases, added as online material, will further enhance the value of this textbook.

Abstrak :
The book begins with a synopsis of the fundamentals aspects of fluid mechanics to give the reader the essential background to address the proceeding chapters. Then the fundamental elements of vortex dynamics will be discussed, explaining the conditions for their formation and the rules governing their dynamics. The main equations are accompanied by mathematical models. Cardiovascular vortex formation is first analyzed in physiological, healthy conditions in the heart chambers and in the large arterial vessels. The analysis is initially presented with an intuitive appeal grounded on the physical phenomena and a focus on its clinical significance.In the proceeding chapters, the knowledge gained from either clinical or basic science literature will be discussed. The corresponding mathematical elements will finally be presented to ensure the adequate diligence. The proceeding chapters ensue to the analysis of pathological conditions, when the reader may have developed the ability to recognize normal from abnormal vortex formation phenomenon. Pathological vortex formation represents vortices that develop at sites where normally laminar flow should exist, e.g. stenosis and aneurisms. This analysis naturally leads to the interaction of vortices due to the surgical procedures with respect to prediction of changes in vortex formation. The existing techniques, from medical imaging to numerical simulations, to explore vortex flows in the cardiovascular systems will also be described.