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Abstrak :
Tesis ini bertujuan untuk menganalisis menganalisis hubungan antara infeksi odontogenik dengan terjadinya komplikasi infeksi sistemik. Penelitian ini merupakan sebuah studi cross sectional dengan desain retrospektif. Hasil penelitian ini menunjukkan bahwa terdapat hubungan yang signifikan antara penyebaran infeksi odontogenik berdasarkan tingkat keparahan menurut Flynn Severity Score terhadap komplikasi infeksi sistemik servikal sellulitis maupun DNM, Sedangkan pada komplikasi infeksi sistemik sepsis, maka kelompok usia pasien dan penyakit penyerta memiliki pengaruh yang signifikan terhadap terjadinya komplikasi infeksi sistemik sepsis tersebut. Sehingga dapat disimpulkan bahwa tingkat keparahan menurut Flynn Severity Score, usia pasien dan penyakit penyerta dapat mempengaruhi terjadinya komplikasi infeksi sistemik berupa servikal selullitis, DNM maupun sepsis. ......This study aims to analyze the relationship between odontogenic infections and the complications of systemic infections. This is a cross sectional study with a retrospective design. The results of this study indicate that there is a significant relationship between the spread of odontogenic infection based on the severity according to the Flynn Severity Score on complications of cervical systemic infection, DNM and sepsis, regarding complications of systemic infections in sepsis group, the patient’s age and accompanying diseases have a significant influence on the occurrence of complications of the sepsis systemic infection. As a conclusion, based on Flynn Severity Score, the patient’s age and accompanying diseases can influence the occurrence of complications of systemic infections in the form of cervical sellulitis, DNM and sepsis

Keywords: cervical cellulitis, DNM, odontogenic infection, sepsis

 

 

 

 

Abstrak :
ABSTRACT
A 59-year-old lady with underlying hypothyroidism presented with acute contact dermatitis progressed to cellulitis with superimposed bacterial infection and acute kidney injury. She responded to initial management with antibiotics, but a week later, she had cutaneous and systemic vasculitis. Her skin biopsy consistent with immune-mediated leuko-cytoclastic vasculitis and her blood test was positive for cytoplasmic-anti-neutrophil cytoplasmic antibody (c-ANCA). A diagnosis of ANCA-associated vasculitis was made and she was treated with immunosuppressant with plasmapheresis and hemodialysis support for her kidney failure. Despite aggressive measures, the patient succumbed to her illness. This case report demonstrates that soft tissue infection could trigger the development of ANCA-associated vasculitis whilst a background of hypothyroidism serves as a predisposing factor as both condition were reported separately in a couple of case studies before.