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"High carbohydrate intake is one of predisposing factors of oral candidiasis. Wheather glucose addition in medium will increase the growth of Candida albicans in vitro is subject to further investigation. Objective: Investigating the effect of 1%, 5%, 10% glucose addition on the growth of C. albicans in vitro. Method: C. albicans sample was taken from oral swab of a male oral candidiasis patient. Identification of C. albicans was conducted using CHROMagar and confirmed by germ tube formation in serum. C. albicans colonies were inoculated in SDB. As a comparison, C. albicans ATCC 10231 was used. After 2 days the cultures were serially diluted and inoculated in SDB without glucose (control), and with 1%, 5%, 10% addditional glucose, kept for 3 and 7 days in room temperature, then inoculated in SDA. The CFU/ml were counted after 2 days. ANOVA with α 0.05 was used. Result: After 3 days, additional 1%, 5%, and 10% glucose in media with clinical strain of C. albicans resulted in 181.5, 582, and 811 CFU/ml respectively while in media with C. albicans ATCC were 21.5, 177.5, 375.5 CFU/ml. The growth of C. albicans with no additional glucose were 970 (clinical strain) and 957 CFU/ml (ATCC). After 7 days, the growth of clinical
strain of C. albicans with additional glucose 1%, 5%, 10% were 2350, 9650, 9560 CFU/ml respectively while the growth of C. albicans ATCC were 5000, 5450, 3550 CFU/ml. Statisticaly, additional 1% glucose for 3 days lead to significant decreased of growth of both clinical strain and
ATCC 10231 C. albicans (p < 0,05). However, only additional 5% and 10% glucose in clinical isolate for 7 days increased the growth of C. albicans significantly (p < 0,05). Conclusion: The effect of additional glucose on the increased growth of C. albicans in vitro is influenced by the concentration, exposure duration of glucose, and by the strain of C. albicans."
[Fakultas Kedokteran Gigi Universitas Indonesia, Journal of Dentistry Indonesia], 2009
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Artikel Jurnal  Universitas Indonesia Library
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Ester Inung Sylvia
"Terapi Reiki merupakan salah satu terapi komplementer untuk membantu menurunkan kadar glukosa darah pasien DM tipe 2. Terapi ini menggunakan energi alami yang disalurkan pada tubuh pasien DM tipe 2 dengan tujuan menyelaraskan energi yang tidak seimbang dalam tubuhnya. Penelitian ini bertujuan untuk mengetahui pengaruh Reiki terhadap penurunan kadar glukosa darah pasien DM tipe 2 di Klub Diabetes Instalasi Rehabilitasi Medis RSUP Fatmawati, Jakarta. Desain penelitian yang digunakan adalah pra-eksperimental dengan pendekatan the one-group pretest-posttest design (before and after) menggunakan teknik purposif sampling untuk pengambilan sampelnya. Sampel berjumlah 18 responden. Terapi Reiki dilakukan dengan dua metode, secara langsung dan dari jarak jauh (distant healing) yang diberikan selama 30 hari. Terapi Reiki dilakukan oleh peneliti dibantu oleh praktisi Reiki khususnya dalam transfer energi. Instrumen yang digunakan untuk mengukur kadar glukosa darah adalah glukometer. Hasil penelitian menunjukkan ada perbedaan yang bermakna antara KGDS sebelum dan setelah intervensi Reiki (p=0,000). Disarankan pemberian asuhan keperawatan menggunakan terapi komplementer Reiki dalam membantu mengatasi masalah kesehatan pasien.

Reiki therapy is one of the complementary therapy that is used to decrease blood glucose level of Type 2 Diabetes Mellitus patient. The therapy employs nature energy which was transferred into patient body to synchronize the imbalance energy in the body. This research was aimed to examine the effect of Reiki in decreasing blood glucose level of patient with Type 2 Diabetes Mellitus at Diabetes Club in Medical Rehabilitation Instalation Fatmawati Hospital, Jakarta. Research design in this study was pre-experimental with the one-group pretest-posttest design (before and after). Purposive sampling technique was employed in sample selection and 18 patients participated in this study. Reiki therapy was performed in two methods, directly and by distant healing, which is done for 30 days. The therapy was conducted by the researcher and helped by Reiki practitioner, especially in the energy transferring. To measure blood glucose level glucometer was instrument. The result revealed that there was a significant difference in casual blood glucose levels before and after Reiki intervention (p=0,000). It is recommended to employ Reiki as a complementary therapy in nursing care."
Depok: Universitas Indonesia, 2008
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UI - Tesis Open  Universitas Indonesia Library
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"Pada dekade terakhir ini para dokter dan penanggung jawab bidang kesehatan mulai menyadari bahwa kegemukan dan berat badan berlebih mempunyai dampak kesehatan yang merugikan seperti timbulnya penyakit diabetes, penyakit jantung pembuluh darah dan penyakit penyerta lain yang lebih dikenal sebagai komorbiditas. Pengukuran tingkat kegemukan yang sudah diterima secara luas adalah yang menggunakan indeks masa tubuh (IMT) dan ukuran lingkar pinggang (LP). Atas dasar itu perlu kiranya Indonesia mempunyai nilai IMT dan LP sendiri, untuk faktor risiko komorbiditas. Penelitian cross sectional ini mencakup 6318 subyek yang terdiri dari 5216 laki-laki (82,6%) dan 1102 wanita (17,6%). Faktor risiko utama komorbiditas, baik pada laki-laki dan wanita adalah peninggian kolesterol dan trigliserida. Resiko timbulnya komorbiditas mulai meningkat pada IMT 24,38 kg/m2 dan lingkar pinggang (LP) 86,25 cm untuk kadar gula darah puasa dan IMT 24,91 kg/m2 dan LP 89,25 cm untuk kadar triglycerida. (Med J Indones 2004; 13: 241-5)

Over the last few years health care providers have become more aware of the consecquences of obesity as well as the comorbidities of obesity. The body mass index (BMI) and waist circumference (WC) became universally accepted measures to determine the degree of overweight. it is necessary to have cut off points for BMI and WC for the risk factors of the comorbidities of obesity in Indonesia. This study has a cross sectional design with a total of 6318 subjects, that comprised of 5216 males (82.6%) and 1102 females (17.6%). The highest percentage of comorbidities both in males and females were high cholesterol and triglyceride level. The risks of comorbidities were increased at BMI 24.38 kg/m2 and WC 86.25 cm for fasting blood glucose and BMI 24.91 kg/m2 and WC 89.25 cm for triglyceride level. (Med J Indones 2004; 13: 241-5)
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Medical Journal of Indonesia, 13 (4) October December 2004: 241-245, 2004
MJIN-13-4-OctDec2004-241
Artikel Jurnal  Universitas Indonesia Library
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Ester Inung Sylvia
"Reiki merupakan terapi komplementer untuk menurunkan kadar glukosa darah. Terapi ini menggunakan energi alami yang disalurkan pada tubuh pasien dengan tujuan menyelaraskan energi yang tidak seimbang dalam tubuhnya. Penelitian untuk mengetahui pengaruh Reiki terhadap penurunan glukosa darah dan mengidentifikasi apakah faktor stres dan berat badan (obesitas) berperan dalam penurunan KGD pasien Diabetes Melitus tipe 2 dilakukan di Klub Diabetes sebuah RS di Jakarta. Desain penelitian pre-eksperimental dengan pendekatan one-group pretest-posttest design. Sejumlah 18 sampel dipilih dengan teknik purposive sampling. Terapi dilakukan selama tiga puluh hari dengan dua metode, secara langsung dan jarak jauh. Hasil penelitian menunjukkan perbedaan bermakna antara glukosa darah sebelum dan setelah intervensi Reiki (p= 0,000; α= 0,05). Penelitian ini menyarankan penggunaan Reiki dalam asuhan keperawatan.

Reiki is one of the complementary therapies that are used to decrease blood glucose level. The therapy transfers natural energy into the patient`s body to synchronize the energy imbalance in the body. The research to examine the effect of Reiki and the role of the stress and weight factor to decrease blood glucose level of DM type 2 patients was held in a hospital-based diabetic club in Jakarta. The design of this study was pre-experimental with the one-group pretest-posttest design. Eighteen patients were selected with the purposive sampling technique. Reiki therapy was performed in 30 days using two methods: direct and distant healing method. The result revealed that there was a significant difference in random blood glucose level before and after the Reiki intervention (p= 0.000; α= 0.05). It is recommended to incorporate the Reiki therapy in nursing care."
Palangkaraya; Depok: Poltekkes Kemenkes Palangkaraya ; Universitas Indonesia. Fakultas Ilmu Keperawatan, 2011
610 JKI 14:2 (2011)
Artikel Jurnal  Universitas Indonesia Library
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Widia Wati
"Diabetes melitus merupakan penyakit kronik yang dapat menimbulkan stress. Relaksasi dengan terapi murotal Al-Qur’an merupakan terapi yang dapat mengatasi hiperglikemia. Penelitian ini bertujuan untuk membuktikan pengaruh terapi murotal Al-Qur’an terhadap kadar glukosa darah pada DM tipe 2. Desain penelitian ini adalah quasi eksperimen pre-post with control group. Jumlah sampel 39 orang dibagi dalam dua kelompok yaitu 20 orang dalam kelompok intervensi dan 19 orang pada kelompok kontrol, pemilihan responden purposive sampling. Uji statistik yang digunakan uji Anova repeated measure. Hasil penelitian didapatkan ada pengaruh terapi murotal Al-Qur’an terhadap penurunan kadar glukosa darah sebesar 61 mg/dl (p=0,029, ). Kesimpulan penelitian ini, terapi murotal Al-Qur’an efektif menurukan kadar glukosa darah pada pasien diabetes melitus tipe 2.

Diabetes mellitus is a chronic disease that can cause stress. Murotal Qur'an relaxation therapy is a therapy that suggested to reduce hyperglycemia. This study aimed to examine the effect of murotal Qur'an therapy on blood glucose levels. This study design was quasi-experimental pre-post with control group. Number of samples are 39 people who were divided into two groups: the intervention group consist of 20 people, and 19 people in the control group, the selection of participants with purposive sampling. Statistical tests were using repeated measure Anova test. The results of this study found there was an effect of murotal Qur'an therapy to decrease blood glucose levels (p = 0.029, ? = 0.05). In conclusion, murotal Qur'an therapy effectively to decrease blood glucose levels in patients with type 2 diabetes mellitus"
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2014
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UI - Tesis Membership  Universitas Indonesia Library
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Atyanti Isworo
"ABSTRAK
Diabetes Mellitus (DM) merupakan gangguan metabolik kronik yang dapat menurunkan aspek kehidupan pasien secara keseluruhan, baik fisik maupun psikologis. Salah satu gangguan psikologis yang sering terjadi adalah depresi dan kondisi ini membutuhkan suatu manajemen komprehensif dengan melibatkan keluarga dalam pemberian pelayanan keperawatan. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara depresi dan dukungan keluarga terhadap kadar gula darah pada pasien DM tipe 2.Desain penelitian menggunakan analytic correlation dengan pendekatan crosssectional. Jumlah sampel pada penelitian ini adalah 166 pasien DM tipe 2 dengan menggunakan teknik pupposive sampling di Poli Klinik Penyakit Dalam RSUD Sragen pada bulan September sampai November 2008. Instrumen CES-D (Center for Epidemiological Studies-Depressed Mood Scale) digunakan untuk mengukur depresi.dan instrumen DFBC (The Diabetes Family Behavior Checklist) untuk menentukan total skor dukungan keluarga. Analisis statistik yang digunakan adalah chi square, t-test independent dan regresi logistik ganda. Hasil penelitian tentang hubungan depresi dan kadar gula darah didapatkan nilai p=0,0005 dan hubungan dukungan keluarga dan kadar gula darah nilai p=0,0005. Pada hubungan antara faktor pengganggu ditemukan bahwa status ekonomi tidak berhubungan dengan kadar gula darah (p=0,052). Dukungan keluarga merupakan faktor paling dominan berhubungan dengan kadar gula darah (OR=9,758). Umur, tingkat pendidikan dan komplikasi merupakan faktor pengganggu. Kesimpulan penelitian ini adalah terdapat hubungan yang bermakna antara depresi dan dukungan keluarga terhadap kadar gula darah pasien DM tipe 2. Hasil penelitian ini merekomendasikan untuk dilakukan skrining tentang depresi pada pasien DM dan melibatkan keluarga merupakan hal yang penting dalam pemberian asuhan keperawatan.

ABSTRACT
Diabetes Mellitus (DM) is a chronic metabolic disease that may have debilitating effect toward the whole life of type 2 diabetic patient, not only the physical aspect but also psychological aspect. Depression is one psychological disorder, therefore this condition requires a comprehensive management with involving family on nursing care. The purpose of this study was to identify the correlation among depression and family support with blood glucose level of type 2 DM patients. This study used an analytic correlational design with cross-sectional approach, recruited 166 respondents by purposive sampling method at Outpatient Ward of Internal Medicine Clinic, Sragen Public Hospital on September until November 2008. The CES-D (Center for Epidemiological Studies-Depressed Mood Scale) was used to assesed depressive symptoms while the DFBC (The Diabetes Family Behavior Checklist) to determine the total score of family support. Chi Square, t-test independent and a multiple logistic regression were used to examine the relationship of depression and family support with blood glucose. The result revealed that there were significant relationships among depression and blood glucose level (p value 0,0005) and family support (p=0,0005). There was no significant correlation between economic status and blood glucose level (p=0,052). In addition, family support became the most dominant factor related to blood glucose level (OR=10,925). Meanwhile, age, education level, and complications became the confounding factors. It concluded that there were relationship among depression and family support with blood glucose level of type 2 DM patients. The findings of this study suggested that screening individuals with diabetes for depressive symptoms and participation of family would be important aspect of diabetes care.
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2008
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UI - Tesis Open  Universitas Indonesia Library
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Ester Inung Sylvia
"Terapi Reiki merupakan salah satu terapi komplementer untuk membantu menurunkan kadar glukosa darah pasien DM tipe 2. Terapi ini menggunakan energi alami yang disalurkan pada tubuh pasien DM tipe 2 dengan tujuan menyelaraskan energi yang tidak seimbang dalam tubuhnya. Penelitian ini bertujuan untuk mengetahui pengaruh Reiki terhadap penurunan kadar glukosa darah pasien DM tipe 2 di Klub Diabetes Instalasi Rehabilitasi Medis RSUP Fatmawati, Jakarta. Desain penelitian yang digunakan adalah pra-eksperimental dengan pendekatan the one-group pretest-posttest design (before and after) menggunakan teknik purposif sampling untuk pengambilan sampelnya. Sampel berjumlah 18 responden. Terapi Reiki dilakukan dengan dua metode, secara langsung dan dari jarak jauh (distant healing) yang diberikan selama 30 hari. Terapi Reiki dilakukan oleh peneliti dibantu oleh praktisi Reiki khususnya dalam transfer energi. Instrumen yang digunakan untuk mengukur kadar glukosa darah adalah glukometer. Hasil penelitian menunjukkan ada perbedaan yang bermakna antara KGDS sebelum dan setelah intervensi Reiki (p=0,000). Disarankan pemberian asuhan keperawatan menggunakan terapi komplementer Reiki dalam membantu mengatasi masalah kesehatan pasien.

Reiki therapy is one of the complementary therapy that is used to decrease blood glucose level of Type 2 Diabetes Mellitus patient. The therapy employs nature energy which was transferred into patient body to synchronize the imbalance energy in the body. This research was aimed to examine the effect of Reiki in decreasing blood glucose level of patient with Type 2 Diabetes Mellitus at Diabetes Club in Medical Rehabilitation Instalation Fatmawati Hospital, Jakarta. Research design in this study was pre-experimental with the one-group pretest-posttest design (before and after). Purposive sampling technique was employed in sample selection and 18 patients participated in this study. Reiki therapy was performed in two methods, directly and by distant healing, which is done for 30 days. The therapy was conducted by the researcher and helped by Reiki practitioner, especially in the energy transferring. To measure blood glucose level glucometer was instrument. The result revealed that there was a significant difference in casual blood glucose levels before and after Reiki intervention (p=0,000). It is recommended to employ Reiki as a complementary therapy in nursing care."
Depok: Universitas Indonesia, 2008
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UI - Tesis Open  Universitas Indonesia Library
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Mohamad Agung Handriawan
"Latar Belakang: Bekerja di lingkungan offshore berpotensi menimbulkan stres kerja. Menurut penelitian sebelumnya stres kerja dapat meningkatkan kadar glukosa darah, Penelitian ini bertujuan mengidentifikasi adanya hubungan antara kadar glukosa darah puasa tinggi dan DM dengan stres kerja serta faktor risiko lainnya pada pekerja offshore.
Metode: Penelitian ini menggunakan desain cross sectional dengan 156 orang responden. Variabel yang diteliti adalah usia, indeks massa tubuh, lingkar perut, dislipidemia,tekanan darah, jabatan pekerjaan, masa kerja, dan stres kerja. Data diperoleh dari penilaian tingkat stress melalui Survei Diagnostik stres dan hasil medical check up tahun 2017. Analisis data menggunakan univariat, bivariat, dan multivariat dengan regresi logistik.
Hasil: Prevalensi glukosa darah puasa tinggi dan diabetes mellitus sebesar 12.2 . Berdasarkan uji Fisher terdapat hubungan yang bermakna antara usia, dislipidemia, jabatan pekerjaan dan masa kerja dengan kadar glukosa darah puasa tinggi dan Diabetes Mellitus , namun pada analisis multivariat hanya faktor jabatan pekerjaaan supervisor merupakan yang paling dominan mempengaruhi dgn OR=7,051 95 CI 1,963-25,325. Tidak ditemukan adanya hubungan antara hasil SDS dengan kadar glukosa darah tinggi dan DM.
Kesimpulan dan saran: Faktor risiko paling dominan terhadap glukosa darah puasa tinggi dan diabetes mellitus adalah faktor jabatan pekerjaan oleh karena itu perlu dilakukan hal-hal sebagai berikut, yaitu skrining hasil MCU untuk pekerja khususnya jabatan supervisor, melakukan pemeriksaan berkala kadar glukosa darah, memperbanyak aktivitas fisik ketika bekerja dilapangan serta program peningkatan kesadaran kesehatan, terutama mengenai pencegahan penyakit Diabetes Mellitus.

Background: Working in offshore environments where workers are placed in remote locations will potentially cause work stress. According to previous researches, work stress can increase blood glucose levels. This study aims to prove Relation of High Fasting Blood Glucose level and DM with Job Stress and Other Risk Factors In Offshore Workers.
Method: This study used cross sectional design with total 156 respondents. The studied variables were age, body mass index, abdominal circumference, dyslipidemia, and blood pressure as well as job risk, job position, working period, and work stress. The tools used to evaluate the stress level were Stress Diagnostic Survey and results of periodic Medical Check up in 2017. The analysis of research data used univariate, bivariate and multivariate analysis with logistic regression.
Study Results: The prevalence of high fasting blood glucose anad Diabetes Meliitus is 12,2 . Using Fisher statistic test, an association was found between age, dyslipidemia, job position,woking period and high fasting blood glucose or diabetes mellitus. But multivariate analyses showed that only job title supervisor is the most dominant influential factor Oradj 7,051 95 CI 1,963 25,325. There was no correlation between SDS results with high fasting blood glucose level and DM.
Conclusion and Suggestion: The employee's job function is the most dominant factor in high fasting blood glucose Diabetes Mellitus, therefore it is important to conduct several activities such as screening on MCU record, particularly on Supervisors conducting routing blood glucose check increasing physical activities at work and carrying out the health awareness program, especially awareness on DM prevention.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2018
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UI - Tesis Membership  Universitas Indonesia Library
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Aulia Suci Pertiwi
"Alyxia reinwardtii dikenal sebagai Pulosari digunakan untuk pengobatan kencing manis dan beberapa penyakit lainnya, memiliki kandungan utama berupa Pulosariosida dan Skopolentin. Penelitian ini dilakukan untuk mengevaluasi efek antidiabetes dan antihiperlipidemia ekstrak etanol dari kulit batang pulosari pada tikus diabetes yang diinduksi kombinasi pakan tinggi lemak, streptozotocin, dan nikotinamid. Untuk mencapai tujuan tersebut, pada penelitian ini menggunakan 24 ekor tikus wistar jantan. Tikus dibagi menjadi enam kelompok (n=4). Kelompok normal dan negatif diberi CMC 0,5%, kelompok positif diberi Metformin dosis 90mg/200g/hari secara oral; dan tiga variasi dosis ekstrak kulit batang pulosari 150mg/kgBB tikus/hari; 300mg/kgBB tikus/hari; 600mg/kgBB tikus/hari secara oral.
Tikus diinduksi pakan tinggi lemak (pakan standar : tallow : sukrosa : mentega, 50%:20%:20%:10%) selama 28 hari dan diinduksi nikotinamid (110mg/kgBB) dengan streptozotocin dosis rendah (40mg/kgBB) dua kali injeksi secara intraperitoneal. Kemudian diberikan baik dengan ekstrak kulit batang pulosari dan metformin selama 21 hari. Dosis 300mg/kg dan dosis 600mg/kg ekstrak pulosari melalui uji Anova memberikan perbedaan bermakna pada kadar glukosa darah setelah 21 hari (p<0,05). Ekstrak kulit batang pulosari memiliki potensi yang sama dengan metformin untuk menurunkan kadar glukosa, kolesterol, trigliserida, LDL dan meningkatkan kadar HDL. Berdasarkan hasil penelitian, ekstrak kulit batang pulosari dapat menurunkan dan memperbaiki profil lipid hewan model.

Alyxia reinwardtii as known as Pulosari is used traditionally for the treatment of diabetes and some other diseases, the main constituent is Pulosarioside and Scopolentin. The aimed of this study to investigate the antidiabetic effects of extract etanol from bark Alyxia reinwardtii in diabetic rats induced by combination of high-fat diet, streptozotocin, and nicotinamide. To this end, we used 24 Wistar male rats. The rats were divided into six groups (n=4). The normal and negative groups were given 0,5% CMC, positive group was given Metformin dose 90mg/200g/day orally; and three variation dose groups of extract pulosari 150 mg/kg BW rats/day orally; 300 mg/kg BW rats/day orally; 600 mg/kg BW rats/day respectively.
All the treatment rats were induced by the combination of high-fat diet (standard feed: tallow: sucrose: butter, 50%:20%:20%:10%) for 28 days and received nicotinamide (110mg/kg BW) with Low dose STZ (40mg/kg BW) twice by intraperitoneal injection. Then treated with extract pulosari either metformin for 21 days. Doses 300mg/kg BW and 600 mg/kg of extract pulosari after 21 days significantly reduced glucose level (p<0,05). The power of extract pulosari similar to metformin to reduce glucose level, cholesterol level, triglyceride level, LDL level, and increase HDL level. Based on this result, pulosari extract have potency as antidiabetic and improve lipid profiles of animal model.
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Depok: Fakultas Farmasi Universitas Indonesia, 2021
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UI - Skripsi Membership  Universitas Indonesia Library
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