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Hendya Perbangkara
Karakterisasi Electronic Portal Imaging Device (EPID) sebagai dosimeter untuk verifikasi IMRT dan VMAT = Characterization of electronic portal imaging device EPID as patient specific QA for IMRT and VMAT
"[Studi ini telah dilakukan untuk mengetahui karakteristik dari EPID dosimetri yang digunakan sebagai verifikasi pasien IMRT dan VMAT. Penelitian ini dilakukan dengan membandingkan indeks gamma dari hasil verifikasi 5 pasien brain, 5 pasien cervix, 5 pasien kepala dan leher serta 5 pasien paru menggunakan EPID dosimetri dengan MatriXX 2D array pada dua Linac yang berbeda di instalasi radioterapi MRCCC SHS dan Siloam Hospital TBS. Dari penelitian ini dihasilkan nilai indeks gamma untuk kasus IMRT di MRCCC 99.59% ± 0.46 untuk EPID dosimetri dan 99.13% ± 0.75 untuk MatriXX 2D array, sedangkan di Siloam Hospital TBS 99.8% ± 0.20 untuk EPID dosimetri dan 99.71% ± 0.14 untuk MatriXX 2D array. Pada kasus VMAT di MRCCC 97.71% ± 1.27 untuk EPID dosimetri dan 99.50% ± 0.39 untuk MatriXX 2D array, sedangkan di Siloam
Hospital TBS 97.78% ± 1.45 untuk EPID dosimetri dan 98.66% ± 1.26 untuk MatriXX 2D array. Kesimpulan dari penelitian ini adalah perbedaan antara EPID dosimetri dan MatriXX 2D array di kedua rumah sakit menunjukan nilai kurang dari 1% untuk kasus IMRT dan kurang dari 2% untuk kasus VMAT.
This work was aimed to study the characteristics of EPID dosimetry in use as patient specific QA for IMRT and VMAT. We compare result of gamma index from patient specific QA with each 5 cases of brain, cervix, head and neck, lung
using EPID dosimetry and MatriXX 2D array in two different linacs at MRCCC SHS and Siloam Hospital TBS. Calculated gamma index from IMRT case in MRCCC SHS ware 99.59% ± 0.46 for EPID dosimetry and 99.13% ± 0.75 for MatriXX 2D array, meanwhile at Siloam Hospital TBS the calculated gamma index were 99.8% ± 0.20 for EPID dosimetry and 99.71% ± 0.14 for MatriXX 2D array.Gamma index from VMAT cases in MRCCC were 97.71% ± 1.27 for EPID dosimetry and 99.50% ± 0.39 for MatriXX 2D array, and in Siloam Hospital TBS the value were 97.78% ± 1.45 for EPID dosimetry and 98.66% ± 1.26 for MatriXX 2D array. We conclude that the difference between EPID dosimetry and Matrixx 2D arrays at two hospitals were less than 1% and less than 2% for IMRT and VMAT cases, respectively. This work was aimed to study the characteristics of EPID dosimetry in use as patient specific QA for IMRT and VMAT. We compare result of gamma index from patient specific QA with each 5 cases of brain, cervix, head and neck, lung using EPID dosimetry and MatriXX 2D array in two different linacs at MRCCC SHS and Siloam Hospital TBS. Calculated gamma index from IMRT case in MRCCC SHS ware 99.59% ± 0.46 for EPID dosimetry and 99.13% ± 0.75 for
MatriXX 2D array, meanwhile at Siloam Hospital TBS the calculated gamma index were 99.8% ± 0.20 for EPID dosimetry and 99.71% ± 0.14 for MatriXX 2D array.Gamma index from VMAT cases in MRCCC were 97.71% ± 1.27 for EPID dosimetry and 99.50% ± 0.39 for MatriXX 2D array, and in Siloam Hospital TBS the value were 97.78% ± 1.45 for EPID dosimetry and 98.66% ± 1.26 for MatriXX 2D array. We conclude that the difference between EPID dosimetry and Matrixx 2D arrays at two hospitals were less than 1% and less than 2% for IMRT and VMAT cases, respectively.;This work was aimed to study the characteristics of EPID dosimetry in use as
patient specific QA for IMRT and VMAT. We compare result of gamma index
from patient specific QA with each 5 cases of brain, cervix, head and neck, lung
using EPID dosimetry and MatriXX 2D array in two different linacs at MRCCC
SHS and Siloam Hospital TBS. Calculated gamma index from IMRT case in
MRCCC SHS ware 99.59% ± 0.46 for EPID dosimetry and 99.13% ± 0.75 for
MatriXX 2D array, meanwhile at Siloam Hospital TBS the calculated gamma
index were 99.8% ± 0.20 for EPID dosimetry and 99.71% ± 0.14 for MatriXX 2D
array.Gamma index from VMAT cases in MRCCC were 97.71% ± 1.27 for EPID
dosimetry and 99.50% ± 0.39 for MatriXX 2D array, and in Siloam Hospital TBS
the value were 97.78% ± 1.45 for EPID dosimetry and 98.66% ± 1.26 forMatriXX
2D array. We conclude that the difference between EPID dosimetry and Matrixx
2D arrays at two hospitals were less than 1% and less than 2% for IMRT and
VMAT cases, respectively., This work was aimed to study the characteristics of EPID dosimetry in use as
patient specific QA for IMRT and VMAT. We compare result of gamma index
from patient specific QA with each 5 cases of brain, cervix, head and neck, lung
using EPID dosimetry and MatriXX 2D array in two different linacs at MRCCC
SHS and Siloam Hospital TBS. Calculated gamma index from IMRT case in
MRCCC SHS ware 99.59% ± 0.46 for EPID dosimetry and 99.13% ± 0.75 for
MatriXX 2D array, meanwhile at Siloam Hospital TBS the calculated gamma
index were 99.8% ± 0.20 for EPID dosimetry and 99.71% ± 0.14 for MatriXX 2D
array.Gamma index from VMAT cases in MRCCC were 97.71% ± 1.27 for EPID
dosimetry and 99.50% ± 0.39 for MatriXX 2D array, and in Siloam Hospital TBS
the value were 97.78% ± 1.45 for EPID dosimetry and 98.66% ± 1.26 forMatriXX
2D array. We conclude that the difference between EPID dosimetry and Matrixx
2D arrays at two hospitals were less than 1% and less than 2% for IMRT and
VMAT cases, respectively.]"
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2016
T44944
UI - Tesis Membership  Universitas Indonesia Library
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Stevy Liura
Perbandingan passing rate indeks gamma berkas sinar-x 6 mv pada beberapa algoritma treatment planning system = Comparison of 6 mv x ray beam gamma index passing rate in many treatment planning system algorithms
"Verifikasi kemampuan algoritma kalkulasi dosis pada Treatment Planning System TPS baru dapat dilakukan dengan membandingkan passing rate hasil analisis indeks gamma dari algoritma yang diuji dengan algoritma yang telah diimplementasikan secara klinis. Oleh karena itu, penelitian ini dilakukan untuk memperoleh passing rate indeks gamma yang dapat digunakan sebagai data referensi dalam verifikasi kemampuan algoritma TPS tiga dimensi. Algoritma yang digunakan dalam penelitian ini ialah Pencil Beam Convolution PBC versi 11.0.31 dan Anisotropic Analytical Algorithm AAA versi 11.0.31 pada TPS Eclipse v.11, serta Fast Convolution FC , Adaptive Convolution AC , dan Collapsed-Cone Convolution CCC pada TPS Pinnacle3 v.7.6c. Konfigurasi berkas sinar-X diatur pada energi 6 MV untuk variasi kedalaman titik pengukuran, luas lapangan, source-to-surface distance, dan sudut wedge. Pengukuran dosis dilakukan dengan menggunakan detektor MatriXX Evolution dan PTW 2D-array seven29. Analisis indeks gamma dilakukan dengan menggunakan OmniPro ImRT dan Verisoft 3.1 untuk kriteria 3 /3mm, 2 /3mm, 3 /2mm, dan 2 /2mm. Secara keseluruhan, passing rate dari AAA cenderung lebih tinggi dibandingkan dengan PBC dan ketiga algoritma konvolusi. Untuk kriteria 2 /2mm, passing rate dari AAA sebesar 93,18 7,21 , passing rate dari PBC sebesar 89,76 7,21 , dan passing rate algoritma konvolusi sebesar 76,84 11,10.
The verification of dose calculation algorithm in a new Treatment Planning System TPS can be evaluated by comparing the passing rate of gamma index analysis result of the evaluated algorithm and the clinically implemented algorithms. In the present investigation, the author investigated the gamma index passing rates as the reference data in the verification of new three dimensions TPS. The algorithms used in this study are Pencil Beam Convolution PBC version 11.0.31 and Anisotropic Analytical Algorithm AAA version 11.0.31 in Eclipse v.11 TPS, and Fast Convolution FC , Adaptive Convolution AC, and Collapsed Cone Convolution CCC in Pinnacle3 v.7.6c TPS. The 6 MV X ray beam configurations were varied in depths of measurement point, field sizes, source to surface distances, and wedge angles. The dose was measured using MatriXX Evolution and PTW 2D array seven29. The gamma index analysis was performed for many gamma criteria 3 3mm, 2 3mm, 3 2mm, and 2 2mm using OmniPro ImRT and Verisoft 3.1. Overall, passing rate of AAA tends to be higher than PBC and three other convolution algorithms. For gamma criteria of 2 2mm, passing rate of AAA was 93,18 7,21 , passing rate of PBC was 89,76 7,21, and passing rate of convolution algorithms was 76,84 11,10."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2016
S66502
UI - Skripsi Membership  Universitas Indonesia Library
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Andrian Dede Handika
Studi distribusi dosis 3D pasien selama penyinaran berbasis MLC log file = Study of 3D dose distribution of patient treatment based on MLC log file
"Banyak peneliti telah menyelidiki log file linac untuk Quality Assurance (QA) teknik Intensity-Modulated Radiation Therapy (IMRT) dan Volumetric Modulated Arc Therapy (VMAT). Dibandingkan antara QA konvensional berdasarkan pengukuran, QA menggunakan log file menawarkan berbagai keuntungan termasuk spasial dan resolusi temporal yang lebih tinggi. Ini berarti QA menggunakan log file tidak memerlukan detektor dan fantom dalam pengukurannya, dan dapat diperoleh secara otomatis serta memberikan informasi untuk pengiriman fraksional setiap pasien. Tujuan dari penelitian ini adalah untuk mengembangkan dan merekonstruksi distribusi dosis 3D untuk QA khusus pasien IMRT berdasarkan log file linac menggunakan metode Modified Clarkson Integration (MCI). Log file dari linac Varian Unique diekstraksi dan dihitung untuk memperoleh distribusi dosis 3D menggunakan MATLAB versi 2016a. Kemudian, distribusi dosis dari log file dibandingkan dengan DICOM RT Dose dari Treatment Planning System (TPS) Eclipse. Kalkulasi dosis menggunakan metode MCI untuk lapangan sederhana dengan berbagai variasi (teknik, luas lapangan, dan kedalaman) memiliki dikrepansi kurang dari ± 2% pada isocenter. Di sisi lain, kalkulasi evaluasi gamma indeks dengan berbagai kriteria Dose Difference (DD) dan Distance to Agreement (DTA) 3%/3 mm, passing rate di atas 95%, sedangkan kriteria untuk 2%/2 mm dan 1%/1 mm di atas 90%. Kalkulasi evaluasi gamma indeks 2D untuk pasien IMRT dengan kriteria 4%/4 mm dan 3%/3 mm, passing rate masing-masing di atas 90% dan 85%. Evaluasi 3D gamma indeks lebih baik daripada 2D untuk kriteria 4%/4 mm dan 3%/3 mm. Hasil ini menunjukkan bahwa metode MCI dan log file dapat digunakan untuk kalkulasi dosis dan alternatif patient-specific QA IMRT.
Many researchers have investigated the linac log file for Intensity-Modulated Radiation Therapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT) Quality Assurance (QA). In comparison between the conventional QA based on measurements, QA using log files offers various advantages including spatial sampling and higher temporal resolution. It does mean not require tools and phantoms in its measurements, but the QA based log file can be automatically generated and provide information for patient fractional delivery. The aim of this study was to develop and reconstruct 3D dose distribution for IMRT patient-specific QA based on linac log file using Modified Clarkson Integration (MCI) method. Linac log file from Varian Unique was extracted and calculated to 3D dose distribution using MATLAB version 2016a. Then, dose distribution from the log file was compared with DICOM RT Dose from Eclipse Treatment Planning System (TPS). Dose calculations using the MCI method for simple open fields of various variations (techniques, field size, and the depth) had discrepancy less than ±2% at isocenter. On the other hand, the calculation of gamma index evaluation with various criteria Dose Difference (DD) and Distance to Agreement (DTA) of 3%/3 mm, the passing rate is above 95%, while the criteria for 2%/2 mm and 1%/1 mm above 90%. Calculation of gamma index evaluation 2D for IMRT patient with various criteria of 4%/4 mm and 3%/3 mm, the passing rate is above 90% and 85%, respectively. Evaluation Gamma Index 3D is better than 2D for criteria 4%/4 mm and 3%/3 mm. This result showed that MCI method and the log file can be used for dose calculation and alternative IMRT patient-specific QA."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2019
T54700
UI - Tesis Membership  Universitas Indonesia Library
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Helga Silvia
Evaluasi indeks gamma pada verifikasi perlakuan radioterapi teknik intensity modulated radiotheraphy imrt dan volumetric modulated arc therapy (VMAT)t = Evaluation of gamma index in the radiotherapy treatment verification of intensity modulated radiotherapy technique imrt and volumetric modulated arc therapy (VMAT)
"Penelitian yang telah dilakukan ini bertujuan untuk mengevaluasi dan menganalisis kesesuaian dosis teknik IMRT dan VMAT antara distribusi dosis pada TPS dengan distribusi dosis yang terukur oleh dosimeter film gafchromic EBT2, MatriXXEvolution dan EPID pada kasus kanker KNF, paru dan prostat. Percobaan dilakukan menggunakan Pesawat Linac Varian Rapid Arc dengan TPS Eclips yang dimiliki oleh Rumah Sakit MRCCC SHS. Pengolahan data dari ketiga dosimeter tersebut menggunakan software MATLAB, Omni Pro IMRT dan portal dosimetry. Untuk perbandingan dilakukan analisis data sekunder yang telah dilakukan oleh pihak RS MRCCC SHS. Hasil penelitian menunjukkan indeks gamma rata-rata data sekunder pasien masih dalam toleransi dengan nilai >90%. Hasil pengukuran menggunakan film EBT2, MatriXXEvolution dan EPID dengan kriteria gamma 3% / 3mm pada kasus kanker KNF, paru dan prostat menunjukan bahwa indeks gamma yang diperoleh melewati batas toleransi yang diizinkan yaitu lebih dari 90%. Selisih indeks gamma antara dosimetri film gafchromic, MatriXXEvolution dan EPID pada teknik VMAT dan IMRT tidak terlalu jauh, dengan rentang 0,01 - 5,36%. Perbedaan indeks gamma menunjukkan bahwa direkomendasikan pengukuran menggunakan detektor MatriXXEvolution daripada menggunakan film dosimetri EBT2 dan EPID. Selisih persentase rata-rata indek gamma pada teknik IMRT dan VMAT berada pada rentang 0,02 - 5,31%. Selisih antara hasil pengukuran dan data sekunder menggunakan MatriXXEvolution dengan hasil penelitian Miura et al. diperoleh dengan rentang 0 - 6%. Data penelitian ini sangat mendukung penelitian yang telah dilakukan sebelumnya oleh Hussein et al., (2013), Nalbant et al., (2014), Elawady et al, (2014), Pham (2013), Miura et al., (2014).
The purpose of this research was to evaluate and analyze the compatibility dose IMRT and VMAT technique between the dose distribution in the TPS and the dose distributions which measured by the film dosimeter gafchromic EBT2, MatriXXEvolution and EPID in the case of KNF cancer, lung and prostat. The experiments were done by using Varian linac Plane Rapid Arc with TPS Eclips owned by the MRCCC Siloam Hospital Semanggi. The data processed of the three dosimeters were using MATLAB software, Omni Pro IMRT and Dosimetry portal. For the comparative analysis of secondary data has been made by MRCCC SHS. The results showed an average gamma index of secondary data patients within tolerances with values > 90%. The measurement results EBT2 film, MatriXXEvolution and EPID of using criteria gamma 3% / 3mm in the case of NPC cancer, lung and prostate indicates that the gamma index gained over the limit allowed tolerance of more than 90%. Gamma index difference between the film dosimetry gafchromic, MatriXXEvolution and EPID on VMAT and IMRT techniques are not too far away, with a range of 0.01 to 5.36%. Differences show that the gamma index measurement using a MatriXXEvolution better than using EBT dosimetry film 2 and EPID. The difference in the average percentage of gamma index on IMRT and VMAT technique to be in the range of 0.02 to 5.31%. The difference between the measurement results and secondary data using MatriXXEvolution and the results Miura et al. Measurement in the range of 0-6%. Data from this study strongly support previous research by Hussein et al., (2013), Nalbant et al., (2014), Elawady et al, (2014), Pham (2013), Miura et al., (2014)."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2016
T44945
UI - Tesis Membership  Universitas Indonesia Library
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Devani Fitriani
Evaluasi dosimetri pada kesalahan multileaf collimator untuk sistem O-Ring Linear Accelerator = Dosimetric evaluation on multileaf collimator error for O-Ring Linear Accelerator system
"Penelitian ini dilakukan untuk mengevaluasi distribusi dosis radioterapi pada kasus kanker payudara, dengan menyelidiki dampak dosimetrik dari kesalahan pemosisian leaf MLC pada Varian Halcyon untuk kesalahan acak, dan untuk mengevaluasi keefektifan jaminan kualitas portal dosimetri dalam menangkap perubahan signifikan secara klinis yang disebabkan oleh kesalahan-kesalahan ini. Kesalahan acak secara sengaja dibuat pada leaf MLC sebesar 5%, 10%, 15%, 20%, 50%, 80%, dan 100% dari total keseluruhan distal MLC Halcyon yang berjumlah 28 pasang, dengan pergeseran daun MLC sejauh 1 mm yang mengacu pada batas nilai toleransi AAPM TG 142. Modifikasi pergeseran leaf MLC memanfaatkan Python, Python dapat membaca file dicom yang dieksport dari TPS eclipse, modifikasi ini dilakukan untuk mengetahui besarnya dosis yang diterima pasien dan menentukan apakah pergeseran leaf MLC tersebut masih dalam rentang yang dapat ditoleransi. Rencana kemudian diberikan pada Linac Varian Halcyon dan fluence ditangkap oleh Electronic Portal Imaging Device (EPID). Distribusi dosis yang diperoleh dievaluasi dengan metode gamma indeks. Hasil evaluasi dan analisis menunjukkan bahwa peningkatan error posisi MLC menyebabkan distribusi dosis yang semakin tidak sesuai dengan batasan dosis, dengan dosis yang diterima oleh PTV semakin menurun yang mempengaruhi kualitas dan efektivitas treatment radioterapi.
The research was conducted to evaluate the radiation dose distribution in breast cancer cases, By investigate the dosimetric impact of multi-leaf collimator positioning errors on Varian Halcyon for random errors, and to evaluate the effectiveness of portal dosimetry quality assurance in capturing clinically significant changes caused by these errors. Random errors were intentionally created in the MLC leaves at 5%, 10%, 15%, 20%, 50%, 80%, and 100% of Halcyon's total of 28 distal MLC pairs, with a 1 mm MLC leaf shift in reference to the AAPM TG 142 tolerance limit values. The modification of the MLC leaf shift utilizes Python, Python can read the dicom file exported from TPS eclipse, this modification is done to determine the amount of dose received by the patient and determine whether the MLC leaf shift is still within the tolerable range. The plan was then administered on a Varian Halcyon linear accelerator and the fluence was captured by an Electronic Portal Imaging Device (EPID). The obtained dose distribution was evaluated by the gamma index method. The results of the evaluation and analysis showed that increasing the MLC position error led to dose distributions that were increasingly out of dose constraint, with the dose received by the PTV decreasing which affected the quality and effectiveness of the radiotherapy treatment."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2024
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UI - Skripsi Membership  Universitas Indonesia Library