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"ABSTRAKZat besi dapat mempengaruhi berat badan dan perkembangan bayi. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara kadar zat besi dengan berat badan pada bayi usia 8-10 bulan di Jakarta Pusat. Metode: Studi cross-sectional digunakan pada 75 bayi yang memenuhi kriteria penelitian. Kadar zat besi diukur menggunakan metode LC-MS/MS Liquid Chromatography ndash; Tandem Mass Spectometry , sedangkan berat badan menggunakan penilaian klinis oleh tenaga terlatih dengan timbangan badan elektronik dengan akurasi 10g. Data dianalisis normalitasnya dengan uji Kolmogorov-Smirnov dan korelasinya dengan uji Spearman. Hasil: Hasil menunjukan tidak terdapat korelasi bermakna antara kadar zat besi dan berat badan bayi 8-10 bulan di Jakarta Pusat p=0,483 . Diskusi: Disimpulkan bahwa hubungan antara kadar zat besi dengan berat badan pada bayi usia 8-10 bulan di Jakarta Pusat bernilai positif, namun secara statistik tidak bermakna.

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ABSTRACTIron can affect the body weight of infants and their development. Objective This research is intended to analyze the correlation between level of iron and body weight in infant aged 8 10 months in Central Jakarta. Method A cross sectional study was conducted in 75 infants that fulfills the criteria for this research. The level of iron was measured by using LC MS MS Liquid Chromatography ndash Tandem Mass Spectrometry method, while the body weight was measured by a trained clinician with an electronic scale. The scale has an accuracy of 10 g. Afterwards the data was analyzed for normality by using Kolmogorov Smirnov test and tested for correlation through Spearman test. Result There is no significant correlation between level of iron and body weight of infants aged 8 10 months in Central Jakarta p 0.483 . Discussion In conclusion, there is a positive relationship between the level of iron and body weight in infant aged 8 10 months in Central Jakarta, however there is no significant relationship. "

"ABSTRAKTelah dilakukan penelitian yang bertujuan untuk mengetahui pengaruh pemberianfortifikan NaFeEDTA dalam tepung tempe terhadap kadar zat besi plasma darah tikus(Rattus norvegicus L.) jantan galur Sprague-Dawley. Metode penelitianmenggunakan Rancangan Acak Lengkap (RAL), terdiri atas 25 ekor tikus putihjantan yang dibagi ke dalam 5 kelompok perlakuan, yaitu kelompok kontrol normal(KK1) yang hanya diberikan CMC 0,5%, kelompok kontrol perlakuan (KK2) yangdiberikan suspensi tepung tempe tanpa fortifikan dan kelompok perlakuan 1, 2, 3(KP1, KP2 dan KP3) yang diberikan suspensi tepung tempe dengan fortifikanNaFeEDTA dosis 1,35 mgFe/ kgBB, 2,7 mgFe/ kg BB, dan 5,4 mgFe/ kgBB.Pemberian bahan tersebut dilakukan secara oral selama 21 hari berturut- turut.Pengambilan darah dilakukan pada hari ke-0 dan setelah perlakuan hari ke-21. KadarFe diukur dengan AAS (Atomic Absorption Spectrophotometer). Hasil uji anava satuarah dan LSD (P < 0,05) terhadap sampel menunjukkan terdapatnya perbedaan nyatapemberian fortifikan NaFeEDTA dalam tepung tempe terhadap kadar zat besi selama21 hari. Peningkatan kadar zat besi tertinggi akhir penelitian (t21) terjadi pada KP 3,yaitu sebesar 27,40% terhadap KK1 dan 24,38% terhadap KK2.

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ABSTRACTThe study has been conducted to know the effect of fortificant NaFeEDTAadministration on tempeh flour to the plasma iron concentration of male rats (Rattus norvegicus L.). Twenty five male rats were divided to five groups consisting of normal control group (KK1) which was administered with CMC 0,5%; treatment control group (KK2) which was administered with tempeh flour without fortificant; and three treatment groups which were administered with tempeh flour and fortificant NaFeEDTA with different doses; 1,35 mgFe/KgBw (KP 1); 2,7 mgFe/KgBw (KP 2); and 5,4 mgFe/KgBw (KP 3). Treatments were carried out orally within 21""consecutive days. Blood is tested before treatment (t0) and after 21 days of treatment (t21). The plasma iron concentrations were measured by Atomic Absorption Spectrophotometer (AAS). Result was statistically tested with SPSS. One-way anova test (P < 0,05) and post hoc LSD test (P <0,005) showed that adding fortificant NaFeEDTA is giving a differences iron concentrations at blood levels of rats from the first day until last day of treatments. Increased iron levels are highest in the KP3 at day 21, which increased 27.40 % compared with KK 1 and 24,38% compared with KK 2."