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"ABSTRAKSuara merupakan modalitas setiap individu untuk berkomunikasi dan berinteraksi. Proses bersuara sangat dipengaruhi keberadaan pita suara. Paralisis pita suara akan mengakibatkan difonia dan mempengaruhi proses komunikasi serta berdampak negatif terhadap kehidupan sosial, aktivitas dan pekerjaan. Penatalaksanaan paralisis pita suara salah satunya dengan laringoplasti injeksi. Prinsip laringoplasti injeksi adalah medialisasi dengan augmentasi. Lemak autologus merupakan salah satu bahan yang baik untuk medialisasi, tetapi memiliki waktu penyerapan beragam dan cenderung cepat terserap sehingga keberadaan lemak didalam jaringan cepat menghilang. Platelet Rich Fibrin (PRF) merupakan bahan yang dapat meningkatkan keberadaan lemak didalam jaringan karena mengandung faktor pertumbuhan. Evaluasi penggunaan kombinasi PRF dengan lemak autologus mikrolobular dibandingkan lemak autologus mikrolobular dilakukan secara subjektif dan objektif. Evaluasi subjektif menggunakan kuesioner Voice Handicap Index (VHI-30) sedangkan evaluasi objektif menggunakan pemeriksaan analisis akustik terkomputerisasi/Multidimensional Voice Program (MDVP), videostroboskopi dan waktu fonasi maksimum. Hasil penelitian ini mendapatkan gambaran perbaikan secara klinis berdasarkan evaluasi VHI-30, MDVP, videostroboskopi dan waktu fonasi maksimum pada masing-masing kelompok penelitian. Tidak terdapat perbedaan bermakna secara statistika evaluasi subjektif dan objektif antara kelompok kombinasi PRF dengan lemak autograf mikrolobular dan kelompok lemak autograf mikrolobular

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ABSTRACTVoice is a modality for every human being to communicate and interact with others. Its process is affected by the presence of vocal cord. Vocal cord paralysis will cause dysphonia, interfering communication, thus result in social activity, and professional aspects in life. One of the management of vocal cord paralysis is injection laryngoplasty. Basic principle of the technique is medialization and augmentation. Autologous fat is one of the best material that can be chosen, but it is very highly absorbable so that its existence in body tissue is quickly disappears. Platelet Rich Fibrin (PRF) is a material that can improve fat tissue longevity due to growth factors as one of the components. Evaluation of combination of PRF and autologous microlobular fat compared with autologous microlobular fat was conducted subjective and objectively. Subjective evaluation was done by using Voice Handicap Index (VHI-30) questionnaire, and objective evaluation was by computerized acoustic analysis/Multidimensional Voice Program (MDVP), videostroboscopy dan maximum phonation time. The result showed clinical improvement according to VHI-30, MDVP, videostroboscopy and maximum phonation time parameters in both research group. There was no statistically important difference in subjective and objective evaluation between PRF and autologous microlobular fat, and autologous microlobular fat group."

"Contested Knowledge argues that the structural coupling between science and media in the context of risk politics has led to the creation of a scientific public sphere in the state of Kerala, India, and regional newspapers have become the most prominent site of public deliberation over science since the late 1990s. This new form of public engagement with science radically differed from its earlier form nurtured by the Kerala Sasthra Sahithya Parishad (KSSP), the largest peoples science movement in India. The book discusses this shift and the resultant transformations of the scientific-citizen public of Kerala by examining three public controversies over science deliberated in the regional dailies in the early 2000s. Public deliberations during the controversies over clinical trials in the Regional Cancer Centre (RCC), Thiruvananthapuram, a series of micro-earthquakes and well collapses, and the strange phenomenon of coloured rain are analysed to understand how risks were perceived, knowledge claims were contested, disciplinary rigidities were dismantled and trust in science and the credibility of scientific institutions were re-negotiated. The book thus explores how the public contestation of knowledge staged by the mass media contributes to deepening democracy by re-instilling politics into science. Democratization of science under the agency of the scientific-citizen publics, the book suggests, is nonetheless limited as it fails to account for alternative forms of engagement offered by multiple publics. The book contends that the theory of deliberative democracy is inadequate to capture the multiplicity of public engagement with science."