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"Latar Belakang: Identifikasi risiko mortalitas pasien non bedah yang masuk ke ruang gawat darurat sangat penting dilakukan karena banyaknya pasien yang datang dengan berat penyakit bervariasi. Rapid Emergency Medicine Score (REMS) dikembangkan untuk memprediksi mortalitas pasien secara cepat sehingga dapat membantu dokter membuat keputusan klinis berdasarkan data yang objektif. Perbedaan karakteristik pasien di Indonesia dapat memengaruhi performa skor tersebut, sehingga perlu dilakukan validasi sebelum sistem skor tersebut digunakan. Tujuan: Menilai performa kalibrasi dan diskriminasi REMS dalam memprediksi mortalitas pasien gawat darurat non bedah di Instalasi Gawat Darurat Rumah Sakit Cipto Mangunkusumo (IGD RSCM). Metode: Penelitian ini merupakan studi kohort prospektif dengan subjek pasien non bedah yang masuk ke IGD RSCM pada bulan Oktober-Desember 2012. Usia, suhu tubuh, mean arterial pressure, denyut jantung, frekuensi pernapasan, saturasi oksigen perifer, dan Glasgow coma scale dinilai saat pasien masuk ke IGD untuk penilaian REMS. Luaran dinilai saat pasien keluar dari RSCM (hidup atau meninggal). Performa kalibrasi dinilai dengan plot kalibrasi dan uji Hosmer-Lemeshow. Performa diskriminasi dinilai dengan area under the curve (AUC). Hasil: Sebanyak 815 pasien non bedah masuk ke IGD RSCM selama penelitian. Terdapat 741 (90,9%) pasien yang berhasil diikuti sampai terjadi luaran dengan angka mortalitas sebanyak 145 pasien (19,57%). Plot kalibrasi REMS menunjukkan koefisien korelasi r = 0,913 dan uji Hosmer-Lemeshow menunjukkan p = 0,665. Performa diskriminasi ditunjukkan dengan nilai AUC 0,77 (IK 95% 0,723; 0,817). Simpulan: Rapid Emergency Medicine Score memiliki performa kalibrasi dan diskriminasi yang baik untuk memprediksi mortalitas pasien non bedah yang masuk ke IGD RSCM. ......Background: Identifying the mortality risk of nonsurgical emergency department (ED) patients is essential as a consequence of increasing number of attendence with diverse severity of disease. Rapid Emergency Medicine Score (REMS) was developed to predict patient?s mortality rapidly, therefore it can help doctors to make clinical decision based on objective data. Difference in characteristic of patients in Indonesia may influence the score?s performance, therefore validation of REMS is needed before applying this scoring system in Indonesia. Objective: To evaluate calibration and discrimination of REMS in predicting mortality of nonsurgical ED patients in Cipto Mangunkusumo Hospital. Methods: This is a prospective cohort study of nonsurgical patients who attended to ED of Cipto Mangunkusumo Hospital in October-December 2012. Age, body temperature, mean arterial pressure, heart rate, respiratory rate, peripheral oxygen saturation, and Glasgow coma scale were obtained when the patient was arrived at emergency room to perform the calculation of REMS. Outcome was assessed when patients were discharge from the hospital (alive or dead). Calibration was evaluated with calibration plot and Hosmer-Lemeshow test. Discrimination was evaluated with area under the curve (AUC). Results: A total of 815 nonsurgical patients attended to ED of Cipto Mangunkusmo Hospital during the study. As many as 741 (90.9%) patients were followed through the outcome. Mortality was observed in 145 patients (19.57%). Calibration plot of REMS showed r = 0.913 and Hosmer-Lemeshow test showed p = 0.665. Discrimination was shown by ROC curve with AUC 0.77 (95% CI 0.723; 0.817). Conclusion: Rapid Emergency Medicine Score showed a good calibration and discrimination in predicting mortality of nonsurgical emergency department patients in Cipto Mangunkusumo Hospital."

"ABSTRAKLatar belakang : Kunjungan dan angka mortalitas pasien di Instalasi Gawat Darurat (IGD) semakin meningkat dengan kondisi penyakit yang bervariasi, sehingga deteksi yang cepat dan tepat pada pasien dengan risiko mortalitas tinggi sangat penting. Skor Hypotension, Oxygen Saturation, Low Temperature, ECG Changes, and Loss of Independence (HOTEL) sangat baik dan penting untuk diterapkan pada pasien gawat darurat karena menggunakan variabel-variabel yang mudah dan cepat diperoleh. Namun demikian skor tersebut belum divalidasi di Indonesia.Tujuan : untuk menilai performa skor HOTEL dalam memprediksi mortalitas 24 jam pasien non bedah di IGD Rumah Sakit Cipto Mangunkusumo (RSCM).Metode: Penelitian ini merupakan studi kohort retrospektif. Subjek penelitian adalah pasien non bedah yang masuk ke IGD RSCM pada bulan Oktober hingga November 2012. Variabel bebas yang dinilai adalah tekanan darah sistolik, saturasi oksigen perifer, suhu tubuh, perubahan elektrokardiogram (EKG), dan kemampuan berdiri tanpa bantuan. Luaran yang dinilai adalah mortalitas dalam 24 jam setelah masuk IGD. Performa kalibrasi dinilai dengan uji Hosmer-Lemeshow. Performa diskriminasi dinilai dengan area under the curve (AUC).Hasil: Terdapat 815 pasien non bedah yang datang ke IGD RSCM selama bulan Oktober hingga November 2012. Sebanyak 804 (98,7%) subjek memenuhi kriteria inklusi dengan mortalitas 24 jam sebesar 30 (3,7%) subjek. Performa kalibrasi HOTEL dengan uji Hosmer-Lemeshow menunjukkan p = 0,753. Performa diskriminasi ditunjukkan dengan nilai AUC 0,86 (IK 95% 0,781; 0,931).Simpulan: Skor HOTEL memiliki performa kalibrasi dan diskriminasi yang baik dalam memprediksi mortalitas 24 jam pada pasien non bedah yang masuk ke IGD RSCM.

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ABSTRACT

Background: The number of visit and mortality rate of emergency patients at Emergency Department (ED) have been increasing from time to time. Those patients have wide spectrum conditions. Appropriate identification of the patients with high mortality risk is crucial. The Hypotension, Oxygen Saturation, Low Temperature, ECG changes, and Loss of Independence (HOTEL) score is easy and important to be applied in the ED, however, the score has not been validated in Indonesia.

Objective: to evaluate performance of HOTEL score in predicting the 24-hour mortality non-surgical patients in ED of Sakit Cipto Mangunkusumo hospital.

Method: This was a retrospective cohort study. The research subjects were the non-surgical patients who admitted to ED of RSCM between October-November 2012. We collected systolic blood pressure, peripheral oxygen saturation, body temperature, ECG changes, and loss of independence. Those data were evaluated based on the HOTEL scoring system. The outcome were evaluated in 24- hour after admission (alive or dead). The calibration was evaluated with the Hosmer-Lemeshow test. The discrimination performance was evaluated with area under the curve (AUC).

Results: There were 815 non-surgical patients admitted to the ED between October until November 2012. There were 804 (98,7%) subjects included. The 24-hour mortality rate was 30 subjects (3,7%). The calibration performance with the Hosmer-Lemeshow test showed p = 0,753. The discrimination performance was shown with the AUC score 0,86 (95% CI 0.781; 0.931).

Conclusion: The HOTEL score has a good calibration and discrimination performance in predicting the 24-hour mortality of the non-surgical patients in ED of Cipto Mangunkusumo hospital."

"ABSTRAKLatar Belakang: Banyaknya pasien yang masuk ke Instalasi Gawat Darurat dengan spektrum penyakit serta derajat berat penyakit yang bervariasi, menimbulkan kesulitan bagi para dokter melakukan penilaian cepat berdasarkan data subjektif saja. Sistem skor Worthing Physiological Scoring System dapat digunakan untuk memprediksi mortalitas pasien non bedah karena menggunakan variabel-variabel yang mudah dan cepat diperoleh, sehingga lebih praktis dalam penggunaannya Oleh karena terdapat perbedaan karakteristik populasi pasien, maka perlu dilakukan validasi untuk mengetahui performa Worthing Physiological Scoring System tersebutTujuan: Menilai performa kalibrasi dan diskriminasi WPS dalam memprediksi mortalitas pasien non bedah selama di IGD Rumah Sakit Cipto Mangunkusumo (RSCM).Metode: Penelitian ini merupakan studi kohort retrospektif pada populasi pasien non bedah yang masuk ke IGD RSCM dari bulan Oktober sampai November 2012. Variabel yang diukur adalah frekuensi pernapasan, denyut jantung, tekanan darah sistolik, suhu tubuh, saturasi oksigen perifer, dan tingkat kesadaran. Luaran yang dinilai adalah kondisi pasien (hidup atau meninggal) selama di IGD RSCM. Performa kalibrasi dinilai dengan uji Hosmer-Lemeshow. Performa diskriminasi dinilai dengan area under the curve (AUC).Hasil: Selama penelitian didapatkan 774 subjek memenuhi kriteria penerimaan dengan 78 (9,6%) subjek di antaranya meninggal. Uji Hosmer-Lemeshow menunjukkan χ2 = 0,84 (p = 0,840). Nilai AUC 0,78 (IK 95% 0,723-0,847).Simpulan: Worthing Physiological Scoring System memiliki performa yang baik dalam memprediksi mortalitas pasien non bedah yang masuk ke IGD RSCM.

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ABSTRACTBackground: Patients referred to Emergency Room (ER) represent a broad spectrum of disease severity, led difficulties for a physicians to conduct rapid assessments based on subjective data only.Worthing Physiological Scoring System could be use to predict mortality in non-surgical patients using variables which are obtained easily and rapidly, making it more practical in use. Because there are differences in the characteristics of the patient population, Worthing Physiological Scoring System should be validated.Objectives: The aim of this study was to assess the performance of Worthing Physiological Scoring System in predicting mortality of non-surgical ER in Cipto Mangunkusumo Hospital (RSCM).Methods: This was a retrospective cohort study. We collected data of non-surgical patients who admitted ER during October to November 2012. The variables measured were respiratory rate, heart rate, systolic blood pressure, body temperature, peripheral oxygen saturation, and level of consciousness. The primary outcomes was death in ER RSCM. Hosmer-Lemeshow test were used to evaluate calibration of Worthing Physiological Scoring System. Discrimination was evaluated with area under the curve (AUC).Result: A total of 774 non surgical patients were included in this study, from the patients, 78 (9.6%) subjects died. Calibration was resulted by Hosmer-Lemeshow test showed χ2 = 0.84 (p = 0.840). The AUC was 0.78 (95% CI 0.723 to 0.847).Conclusion: Worthing Physiological Scoring System had a good performance in predicting mortality of non-surgical patients in ED RSCM. "

"Latar Belakang: Pasien yang datang ke IGD memiliki penyakit yang berbeda dan tingkat keparahan yang juga berbeda. Sistem skor dapat digunakan untuk menilai tingkat keparahan pasien IGD dan dapat memprediksi mortalitas pasien. Simple Model Score (SMS) yang merupakan sistem skor yang menggunakan data laboratorium dasar disertai umur sebagai variabelnya, telah terbukti memiliki performa yang baik. Namun untuk dapat digunakan pada karakteristik pasien yang berbeda, SMS perlu divalidasi.Tujuan: Menilai performa kalibrasi dan diskriminasi SMS dalam memprediksi mortalitas tujuh hari perawatan pasien gawat darurat non bedah yang masuk ke Instalasi Gawat Darurat Rumah Sakit Cipto Mangunkusumo (IGD RSCM).Metode: Penelitian ini merupakan studi kohort retrospektif dengan subjek pasien non bedah yang masuk ke IGD RSCM pada bulan Oktober-November 2012. Data usia, hemoglobin, trombosit, leukosit, ureum, natrium, dan glukosa saat pasien masuk ke IGD digunakan untuk penilaian SMS. Luaran dinilai pada tujuh hari perawatan (hidup atau meninggal). Performa kalibrasi dinilai dengan plot kalibrasi dan uji Hosmer-Lemeshow. Performa diskriminasi dinilai dengan area under the curve (AUC).Hasil: Terdapat 701 pasien yang memenuhi kriteria penelitian ini. Pasien yang meninggal sebanyak 92 pasien (13,12%). Plot kalibrasi SMS menunjukkan koefisien korelasi r=0,639 dan uji Hosmer-Lemeshow menunjukkan p = 0,749. Performa diskriminasi ditunjukkan dengan nilai AUC 0,665 (IK 95% 0,610; 0,719).Simpulan: Simple Model Score memiliki performa kalibrasi yang baik namun performa diskriminasi yang kurang baik untuk memprediksi mortalitas tujuh hari perawatan pasien non bedah yang masuk ke IGD RSCM.

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Background: Patients who came to emergency department (ED) had different diagnosis and severity spectrums. Scoring system could stratify the risk of ED patients and predict their mortality. Simple Model Score (SMS) utilizing age and laboratory data as variables was already proven as a instrument with good performance. Nevertheles, the application of SMS in different characteristic population, should be validated.

Objective: To evaluate calibration and discrimination of SMS in predicting seven day in hospital mortality of nonsurgical ED patients at Cipto Mangunkusumo Hospital.

Methods: This was a retrospective cohort study of nonsurgical patients who attended to ED of Cipto Mangunkusumo Hospital in October-November 2012. The data of age, hemoglobin, platelet count, white blood count, ureum, sodium and blood glucose level when the patient was admitted to emergency room used to perform the calculation of SMS. The primary outcome was seven day in hospital mortality. Calibration was evaluated with calibration plot and Hosmer-Lemeshow test while discrimination was evaluated with area under the curve (AUC).

Results: There were 701npatients who met the criteria were recruited to this study. Mortality was observed in 92 patients (13.12%). Calibration plot of SMS showed r = 0.639 and Hosmer-Lemeshow test showed p = 0.749. Discrimination was shown by ROC curve with AUC 0.665 (CI 95% 0.610; 0.719).

Conclusion: Simple Model Score showed a good calibration despites less satisfying discrimination in predicting seven day in hospital mortality of nonsurgical ED patients at Cipto Mangunkusumo Hospital."