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"Latar Belakang. Indonesia adalah negara agraris dengan 45 % penduduknya bekerja sebagai petani. Untuk meningkatkan hasil pertanian, melindungi tanamannya dari serangan hama, serta memelihara mutu tanahnya, petani banyak menggunakan pestisida. Salah satu penyakit akibat pajanan pestisida adalah dermatitis kontak yang angka prevalensinya pada petani di Indonesia belum diketahui. Karena itu perlu dilakukan penelitian untuk mengetahui prevalensi dermatitis kontak pada petani, khususnya petani sayur, serta faktor-faktor lain yang mempengaruhinya.Metode. Penelitian ini menggunakan disain krosseksional dengan jumlah subyek penelitian 436 orang petani sayur dari Kecamatan Lembang Kabupaten Bandung. Pengumpulan data dilaksanakan sejak September sampai Nopember 2002. Hasilnya diolah menggunakan program statistik SPSS 10.Hasil. Ditemukan 40 orang (9.2 %) penderita dermatitis kontak klinis dan 72 orang (16.5 %) penderita dermatitis kontak subyektif. Risiko terjadinya dermatitis kontak (klinis dan subyektif) dipengaruhi oleh faktor kerja langsung dengan pestisida (OR = 8.636), riwayat atopi (OR = 2.519), dan bentuk formula pestisida yang digunakan (OR = L589). Risiko terjadinya dermatitis kontak klinis dipengaruhi oleh faktor riwayat atopi (OR = 2,998) dan bentuk formula pestisida yang digunakan (OR = 1065). Terhadap risiko terjadinya dermatitis kontak subyektif tidak ditemukan faktor yang dominan berpengaruh.Kesimpulan. Ditemukan prevalensi dermatitis kontak pada petani sayur sebesar 25.7 %. Hubungan antara pajanan pestisida organofosfat dengan dermatitis kontak pada petani sayur di Kecamatan Lembang dipengaruhi oleh faktor kerja langsung dengan pestisida, jumlah tugas saat bekerja dengan pestisida, bentuk formula pestisida yang digunakan, serta riwayat atopi.

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The Correlation between Organophosphate Pesticide Exposure and Contact Dermatitis among Vegetable Farmers in the District of LembangBackground. Indonesia is an agricultural country, in which about 45 % of its populations are farmers. To improve the harvest, to prevent pests attack, and to maintain the fertility of their land , they use very large amount of pesticides. No prevalence data on contact dermatitis caused by exposure to pesticide among Indonesian farmers is currently available. So, a research to find the prevalence of contact dermatitis among farmers, especially vegetable farmers, and other influential factors was proposed.Method. Cross sectional design was used. The subjects consisted of 436 vegetable farmers from Lembang Subdistrict of Bandung District. Data collecting was performed from September to November 2002, and processed by utilizing SPSS 10 program.Result. 40 persons (9.2 %) suffered from clinical contact dermatitis and 72 persons (16.5 %) from subjective contact dermatitis. The risks of contact dermatitis (clinical and subjective) was influenced by direct work with pesticides (OR = 8.636), atopic history (OR = 2.519), and the pesticide formulations (OR = 1.589). While clinical contact dermatitis was influenced by atopic history (OR = 2.998) and pesticide formulations (OR = 2.065). No dominant factor that influenced the risk of subjective contact dermatitis was found.Conclusion. The prevalence of contact dermatitis among vegetable farmers was 25.7 %. The correlation between organophosphate exposure and contact dermatitis among vegetable farmers in the District of Lembang were influenced by the direct work with pesticides, the number of tasks while working with pesticides, the pesticide formulations, and the atopic history."

"Latar belakang. Paparan organofosfat (OP) telah diketahui menyebabkan beberapa penyakit neurologis. Paparan OP yang tinggi dapat ditemukan pada pekerjaan seperti pekerja pestisida. Penelitian saat ini menunjukkan bahwa paparan OP kronis juga dapat menyebabkan gangguan mental, seperti depresi.Metode. Pencarian literatur dilakukan pada database seperti Pubmed, Cochrane Library, dan Science Direct dengan kata kunci pekerja pestisida, organofosfat, dan depresi. Tiga artikel dipilih dan dinilai secara kritis.Hasil. Satu studi kasus-kontrol menunjukkan bahwa pasien dengan depresi memiliki rasio odds sebanyak 1,34 untuk terkena OP. Satu studi kohort prospektif menunjukkan bahwa pekerja yang terpapar OP 1,17 lebih mungkin menderita depresi di masa depan. Satu studi cross-sectional menunjukkan bahwa pasien dengan depresi memiliki rasio odds prevalensi sebanyak 5,39 untuk terkena OP.Kesimpulan. Paparan organofosfat kronis merupakan faktor risiko untuk mengembangkan depresi pada pekerja pestisida.

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Background. Organophosphate (OP) exposure has been well known to cause several neurological diseases. High OP exposure can be found at occupations such as pesticide workers. Current research suggests that that chronic OP exposure may also cause mental disorder, such as depression.

Method. Literature searching was done on database such as Pubmed, Cochrane Library, and Science Direct with pesticide workers, organophosphate, and depression as the keywords. Three articles were selected and critically appraised.

Result. One case-control study showed that patients with depression had odds ratio as much as 1.34 to be exposed to OPs. One prospective cohort study showed that OP-exposed workers were 1.17 more likely to suffer from depression in the future. One cross-sectional study showed that patients with depression had prevalence odds ratio as much as 5.39 to be exposed to OPs.

Conclusion. Chronic organophosphate exposure is a risk factor for developing depression in pesticide workers."