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"Glaukoma merupakan suatu kelompok neuropati optik progresif yang ditandai dengan kelainan struktural dan fungsi saraf optik. Fungsi penglihatan yang paling terganggu pada penderita glaukoma adalah lapang pandangan. Pemeriksaan perimetri berguna untuk mengidentifikasidan mengukur defek lapang pandangan serta memperkirakan progresivitas glaukoma. Aplikasi perimetri berbasis tablet atau website sangat berguna untuk pemantauan pasien selama pandemi Covid-19 dan dapat digunakan di daerah terpencil dengan keterbatasan alat Humphrey Field Analyzer (HFA). Perimetri Melbourne Rapid Fields (MRF) merupakan teknologi baru yang terjangkau, mudah dibawa dan andal, serta dapat memberikan manfaat yang sama dengan perimetri HFA. Tujuan: Menilai kesesuaian hasil perimetri MRF terhadap HFA pada pasien glaukoma derajat sedang– berat dengan tajam penglihatan terganggu. Metode: Penelitian observasional dengan desain potong lintang untuk menilai hubungan tajam penglihatan terhadap kesesuaian hasil perimetri MRF 24-2 dibandingkan dengan HFA 24-2 pada pasien glaukoma derajat sedang-berat. Dilakukan pengelompokan subjek ke dalam dua grup berdasarkan tajam penglihatan. Setiap subjek dilakukan pemeriksaan dengan dua macam alat, urutan pemeriksaan dilakukan randomisasi blok. Pemeriksaan perimetri HFA sebanyak satu kali dan pemeriksaan MRF sebanyak dua kali. Hasil pemeriksaan yang memenuhi kriteria dilakukan analisis komparatif, korelasi, kesesuaian, serta test-retest repeatability. Hasil: Total 64 mata dari 57 subjek terbagi dalam dua kelompok. Durasi pemeriksaan MRF lebih singkat dibanding HFA (265,7 ± 26,6 vs 384,4 ± 46,7, p < 0,001). Tidak terdapat perbadaan bermakna pada indeks reliabilitas kedua alat. MRF menunjukkan korelasi dan kesesuaian yang sangat kuat dan baik dengan HFA (R = 0,931, ICC = 0,957, p < 0,001 pada hasil mean deviation (MD) dan R = 0,941, ICC = 0,974, p < 0,001 pada hasil Visual Field Index (VFI)). Test-retest repeatability MRF menunjukkan korelasi dan kesesuaian yang sangat baik (R = 0,948, ICC = 0,989, p < 0,001 pada hasil MD dan R = 0,946, ICC = 0,989, p < 0,001 pada hasil Visual Capacity (VC)). Tidak didapatkan korelasi antara tajam penglihatan dengan Root Mean Squared Error (RMSE) hasil MRF, p > 0,05. Kesimpulan: Hasil perimetri MRF memiliki korelasi yang sangat kuat dnegan HFA. MRF juga menunjukkan hasil test-retest repeatability yang sebanding dengan HFA.Keakuratan hasil MRF tidak berkorelasi dengan perbedaan tajam penglihatan. ......Background: Glaucoma is a group of progressive optic neuropathy characterized by structural and functional abnormalities of the optic nerve. The most impaired visual function in glaucoma sufferers is the visual field. Perimetric examination is useful for identifying and measuring visual field defects and predicting the progression of glaucoma. Tablet or website-based perimetry applications are very useful for monitoring patients during the Covid-19 pandemic and can be used in remote areas with limited Humphrey Field Analyzer (HFA) perimetry. Melbourne Rapid Fields (MRF) is a new perimetry technology that is affordable, portable and reliable, also can provide the same benefits as HFA perimetry.Objective: To assess the agreement of MRF perimetry results with HFA in moderate to severe glaucoma patients with impaired visual acuity.Methods: Observational study with a cross-sectional design to assess the relationship of visual acuity to the agreement of perimetry MRF 24-2 versus HFA 24-2 in patients with moderate-to-severe glaucoma. Subjects were grouped into two groups based on visual acuity. Each subject was examined with two kinds of perimetry, the order of examination was randomized using block randomization. Participants were tested once on HFA and twice on MRF. Examination results that meet the criteria are analyzed for comparative, correlation, agreement, and test-retest repeatabilityResults: A total of 64 eyes from 57 subjects were divided into two groups. MRF examination duration was shorter than HFA (265.7 ± 26.6 vs 384.4 ± 46.7, p < 0.001). There is no significant difference in the reliability index of the two perimetry. MRF showed a very strong and good correlation and agreement with the HFA (R = 0.931, ICC = 0.957, p < 0.001 in the mean deviation (MD) and R = 0.941, ICC = 0.974, p < 0.001 in the results of the Visual Field Index (VFI)). The MRF test-retest repeatability showed a very good correlation and agreement (R = 0.948, ICC = 0.989, p < 0.001 on the MD and R = 0.946, ICC = 0.989, p < 0.001 on the Visual Capacity (VC)). There was no correlation between visual acuity and Root Mean Squared Error (RMSE) MRF, p > 0.05. Conclusion: The perimetry results from MRF have a very stong correlation to the HFA outcomes. MRF reveals test-retest repeatability comparable to HFA. The accuracy of MRF results did not correlate with differences in visual acuity."

"Latar belakang. Penelitian ini bertujuan mendapatkan gambaran data dasar nilai normal pERG, ketebalan RNFL dan GCIPL pada subjek normal dan subjek dengan POAG derajat early, moderate dan severe serta menilai korelasi antara masing-masing modalitas pemeriksaan.Metode. Penelitian potong lintang yang dilakukan pada 36 mata normal dan 42 mata dengan POAG (derajat early, moderate dan severe) usia 18-60 tahun di RSCM. Semua subjek menjalani pemeriksaan oftalmologi dasar dan pemeriksaan penunjang yaitu Humphrey standard automated perimetry, OCT peripapil dan makula menggunakan CirrusTM dan pERG menggunakan MonPack One dari Metrovision.Hasil. Berdasarkan data normal didapatkan ketebalan rerata RNFL 106,3 ± 11,0 μm, ketebalan rerata GCIPL 83,3 ± 3,5 μm, waktu implisit P50 52,7ms , amplitudo P50 7,9 (3,4 – 15,6) μV, waktu implisit N95 101,3 ± 5,2 ms, amplitudo N95 10,6 (6,0 – 18,7) μV. Dibandingkan dengan kelompok POAG early didapatkan perbedaan bermakna pada ketebalan RNFL (p = 0,007), amplitudo P50 (p = 0,005) dan amplitudo N95 (p = 0,004), tanpa perbedaan bermakna pada ketebalan GCIPL, sedangkan pada kelompok moderate dan severe didapatkan perbedaan pada semua variabel (p<0,05). Korelasi positif sedang dan lemah ditemukan pada kelompok normal antara ketebalan RNFL dengan amplitudo P50 dan N95, tidak ada korelasi hasil pemeriksaan pERG dengan ketebalan GCIPL.Kesimpulan. Pattern ERG adalah pemeriksaan objektif yang dapat membedakan antara kelompok normal dengan POAG, pemeriksaan pERG pada POAG harus memperhatikan floor effect.......Introduction. The study aims to evaluate and compare the pERG result, RNFL and GCIPL thickness in normal group to the groups with early, moderate and severe POAG and evaluate its correlation.Methods. Cross-sectional study was done on 36 normal eyes and 42 eyes with POAG (mild, moderate and severe),subjects with age range of 18-60 years old in RSCM Kirana. Each group underwent complete basic ophthalmology examinations, Humphrey standard automated perimetry, peripapillary and macular OCT CirrusTM and MonPack One pERG from Metrovision.Results. The data on normal group were as follow: RNFL thickness 106,3 ± 11,0 μm, GCIPL thickness 83,3 ± 3,5 μm, P50 implicit time 52,7 ms , P50 amplitude 7,9 (3,4 – 15,6) μV, N95 implicit time 101,3 ± 5,2 ms, N95 amplitude 10,6 (6,0 – 18,7) μV. Significant differences were found in RNFL thickness (p = 0,007), P50 amplitude (p = 0,005) and N95 amplitude (p = 0,004) in the early POAG group compared to the normal group, meanwhile on moderate and severe group all of the variable examination result including the GCIPL thickness were significantly different (P<0,05). Positive moderate and weak correlations were found between RNFL thickness in normal group with P50 and N95 amplitude, no correlation between pERG result with GCIPL thickness.Conclusion. Pattern ERG is an objective tools to differentiate between normal and POAG subjects, pERG examination in POAG group especially the severe group needs to evaluate the floor effect by doing the prior OCT examination."