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"This reference discusses the predictive power and limitations of current stress testing strategies and emphasizes the critical role of stress testing in the determination of the stability characteristics of pharmaceuticals-offering an extensive compilation of drug degradation studies from real-world examples in the literature. Richly illustrated and extensively referenced, this source details the execution and interpretation of small molecule stress testing studies, provides a comprehensive overview of the major aspects of the prediction of drug degradation, presents up-to-date approaches to pharmaceutical stress testing, and much more"

"Presenting an overview of chiral drugs and their impact on the pharmaceutical industry, Chiral drugs : chemistry and biological action provides an integrated perspective of chiral drugs from concept, synthesis, and pharmaceutical properties. The book includes important chiral technologies and reviews of 200 chiral drugs that have either been approved or made it to advanced trials. It's interdisciplinary approach combines synthetic organic chemistry, medicinal chemistry, and pharmacology in a way that fosters cooperation among interdisciplinary scientists and researchers in both academia and the pharma or biotech industries."

"Pemusnahan obat merupakan bagian dari standar pelayanan kefarmasian yang harus diterapkan di seluruh fasilitas pelayanan kesehatan. Pemusnahan sediaan farmasi, alat kesehatan, dan bahan medis habis pakai yang tidak dapat digunakan lagi baik karena kedaluwarsa maupun rusak harus dilakukan dengan tata cara yang sesuai dengan ketentuan peraturan perundang-undangan yang berlaku. Pemusnahan obat yang tidak layak pakai penting untuk dilakukan dengan benar sesuai dengan peraturan yang berlaku guna menjaga keamanan lingkungan. Pengelolaan limbah sediaan farmasi yang tidak benar dapat membahayakan lingkungan, yakni dapat menyebabkan kontaminasi pada air dan tanah. Untuk itu, pada laporan ini akan dibahas mengenai pemusnahan obat sediaan solid dan antibiotik yang terdapat di Apotek Kimia Farma sesuai dengan ketentuan pada Peraturan Menteri Kesehatan Republik Indonesia Nomor 73 Tahun 2016 Tentang Standar Pelayanan Kefarmasian di Apotek dan Pedoman Pengelolaan Obat Rusak dan Kedaluwarsa di Fasilitas Pelayanan Kesehatan dan Rumah Tangga (2020).

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Drug destruction is part of pharmaceutical service standards that must be implemented in all health service facilities. Destruction of pharmaceutical preparations, medical devices, and consumable medical materials that cannot be used because they are expired or damaged must be carried out in a right way that follows the provisions of applicable laws and regulations. It is important to destroy drugs that are not suitable for use properly by applicable regulations to maintain environmental safety. Improper management of pharmaceutical waste can harm the environment, like it can cause contamination of water and soil. For this reason, this report will discuss the destruction of solid preparation drugs and antibiotics found in Kimia Farma Pharmacy in accordance with the provisions of the Regulation of the Minister of Health of the Republic of Indonesia Number 73 of 2016 concerning Pharmaceutical Service Standards in Pharmacies and guidelines for Managing Damaged and Expired Medicines in Health and Home Care Facilities (2020)."

"This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined."

"Apotek merupakan salah satu sarana pelayanan kefarmasian dimana dilaksanakannya praktik kefarmasian oleh Apoteker. Kegiatan pelayanan di apotek telah berkembang menjadi layanan komprehensif untuk meningkatkan kualitas hidup pasien atau pharmaceutical care. Konsep pharmaceutical care berkaitan dengan konsep dasar Good Pharmacy Practice (GPP). Good Pharmacy Practice atau GPP merupakan panduan internasional mengenai praktik kefarmasian yang dibuat oleh International Pharmaceutical Federation (FIP) yang berkolaborasi dengan World Health Organization. Menurut panduan GPP, apoteker harus memastikan bahwa kondisi penyimpanan yang disediakan telah tepat untuk semua obat terutama obat yang perlu pengawasan khusus. Tujuan laporan PKPA ini adalah untuk menganalisis implementasi aspek penyimpanan di KFA No. 382 yang disesuaikan pada panduan Good Pharmacy Practice (GPP). Analisis didasarkan dari observasi dan impementasi panduan GPP mengenai aspek penyimpanan sediaan obat di Apotek Kimia Farma No. 382. Berdasarkan hasil analisis, prosedur penyimpanan sudah hampir sepenuhnya menerapkan panduan Good Pharmacy Practice (GPP) yaitu sebanyak 95,65% atau 22 variabel sesuai dengan poin-poin yang diatur dalam panduan GPP. Namun, masih terdapat satu variabel (4,35%) yang belum sesuai dengan panduan GPP.

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The pharmacy is one of the pharmaceutical service structures where pharmaceutical practices are carried out by pharmacists. Service activities in pharmacies have turned into comprehensive services to improve patient’s quality of life (pharmaceutical care). The concept of pharmaceutical care is linked to the basic concept of good pharmacy practice (GPP). Good pharmacy practice (GPP) is an international guide to pharmaceutical practice created by the Federation of International Pharmaceuticals (FIP) in collaboration with the World Health Organization. According to GPP guidelines, pharmacists must ensure that the storage conditions provided are appropriate for all medicines, especially those that require special supervision. The purpose of this PKPA report is to analyze the implementation of archiving aspects in KFA No. 382 adapted to the guidelines of good pharmacy practice (GPP). The analysis is based on the observation and implementation of the GPP guidelines relating to aspects of the conservation of medicines at the Kimia Farma pharmacy No. 382. Based on the results of the analysis, the storage procedure almost fully implemented the guidelines of good pharmacy practice (GPP), i.e., 95.65% or 22 variables according to the points set out in the GPP guidelines. However, there is still one variable (4.35%) that does not comply with GPP guidelines."