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Abstrak :
As implied in the title of this textbook, Biosensors: From Electric Circuits to Immunosensors , we are going to learn both electric circuitry (in relation to conventional sensors such as temperature sensors) and biosensors (such as antibody-based immunosensors), with equal emphasis on both. The overarching aim is to build an antibody-based immunosensor from scratch. Before we begin this textbook, let us defi ne two important terms: sensors and biosensors. Let us start with sensors. Literally, a sensor is a device used to sense a physical variable, which includes, but is not limited to: temperature, strain, humidity, pressure, mass, light, and voltage. To sense these variables, we need to convert them into a universal and easily accessible signal— usually a voltage . This voltage signal changes continuously with time, and is directly proportional to a corresponding physical variable. A component responsible for this conversion is a transducer . The resulting voltage signal is usually an analog signal. The analog voltage signal is usually transferred to a computer or a microprocessor, which recognizes digital signals only. An analog signal is converted into a series of high and low voltages (i.e., binary numbers), such that a small fl uctuation in the analog signal (i.e., noise) does not affect the overall digital signal. An analog-to-digital converter (A/D converter) performs this conversion. Today, all-in-one type sensors have become very popular. They incorporate a transducer, an A/D converter, a microprocessor, and a small liquid crystal display (LCD) panel. The signal can also be sent to a computer’ s universal serial bus (USB) from an A/D converter.

Abstrak :
This book provides a comprehensive overview of the photonic sensing field by covering plasmonics, photonic crystal, and SOI techniques from theory to real sensing applications. A literature review of ultra-sensitive photonic sensors, including their design and application in industry, makes this a self-contained and comprehensive resource for different types of sensors, with high value to the biosensor sector in particular. The book is organized into four parts: Part I covers the basic theory of wave propagation, basic principles of sensing, surface plasmon resonance, and silicon photonics; Part II details the computational modeling techniques for the analysis and prediction of photonic sensors; Part III and Part IV cover the various mechanisms and light matter interaction scenarios behind the design of photonic sensors including photonic crystal fiber sensors and SOI sensors. This book is appropriate for academics and researchers specializing in photonic sensors; graduate students in the early and intermediate stages working in the areas of photonics, sensors, biophysics, and biomedical engineering; and to biomedical, environmental, and chemical engineers.