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"ABSTRACTPurposesVascular surgery (VS) has a higher perioperative mortality than other types of surgery. We compared different scores for predicting mortality in patients admitted to the intensive care unit (ICU) after open VS.MethodsPatients admitted to the ICU after open VS from 2006 to 2013 were included. We calculated the Acute Physiology and Chronic Health Evaluation (APACHE), Simplified Acute Physiology Score (SAPS), Physiological and Operative Severity Score for the enUmeration of Mortality and Morbidity (POSSUM) and Preoperative Score to Predict Postoperative Mortality (POSPOM). We performed multivariate logistic regression to assess independent factors with the calculation of odds ratios (ORs) and 95% confidence intervals (CIs). We tested the predictive ability of the scores using the area under the receiver operating characteristics curve (AUROC).ResultsA total of 833 consecutive patients were included. Hospital mortality was 5,1% (1,3% after intermediate-risk and 8,4% after high-risk surgery). In the multivariate analysis, the age (OR 1,04, 95% CI 1,01-1,08, p = 0,013), smoking status (OR 2,46, 95% CI 1,16-5,21, p = 0,019), surgery risk (OR 2,92, 95% CI 1,058,08, p = 0,040), serum sodium level (OR 1,17, 95% CI 1,10-1,26, p < 0,001), urea (OR 1,01, 95% CI 1,01-1,02, p = 0,001) and leukocyte count (OR 1,05, 95% CI 1,01-1,10, p = 0,009) at admission were considered independent predictors. Hematocrit (0,86, 95% CI 0,80-0,93, p < 0.001) was considered an independent protective factor. The AUROC of our model was 0,860, compared to SAPS (0,752), APACHE (0,774), POSPOM (0,798) and POSSUM (0,829).ConclusionThe observed mortality was within the predicted range (1-5% after intermediate-risk and > 5% after high-risk surgery). POSSUM and POSPOM had slightly better predictive capacity than SAPS or APACHE."

"La sophistication des techniques de cathétérisme et des agents d'embolisation amenés par voie endovasculaire a contribué à un essor considérable des techniques d'occlusion endovasculaire, tant au niveau des troncs artériels et veineux qu'au niveau du lit capillaire parenchymateux distal. Thérapeutiques mini-invasives, embolisation et chimioembolisation par voie endovasculaire constituent désormais des alternatives thérapeutiques très intéressantes, à titre palliatif ou curatif, en oncologie, en traumatologie, pour des pathologies fonctionnelles ou pour la prise en charge de complications post-opératoires. Des connaissances approfondies très détaillées sont disponibles dans des traités exhaustifs destinés aux spécialistes. L’ambition des auteurs est plutôt ici de fournir un manuel pour les jeunes radiologues vasculaires en formation, et un aide-mémoire pour les radiologues vasculaires en activité, en présentant pour chaque indication une approche synthétique de la réalisation technique de l'acte, de sa place, et des résultats attendus.La première partie de ce livre concerne la « boite à outils » des matériaux et techniques utilisés, et les bases physiopathologiques de l'embolisation, la seconde partie envisage de façon analytique les principales situations et stratégies anatomo-cliniques. Complet et didactique, il devrait figurer à portée de main des radiologues interventionnels et des cliniciens dans les salles de staffs multidisciplinaires et dans les salles d'angiographie."

"Pendahuluan: Chronic limb-threatening ischemia (CLTI) terjadi pada pasien dengan nyeri saat istirahat akibat oklusi arteri. Sekitar 20% dikategorikan sebagai CLTI no option, yaitu keadaan tidak bisa atau gagal dilakukan revaskularisasi. Terapi sel punca menggunakan tipe mesenkimal (MSC) menawarkan pendekatan regeneratif terbarukan melalui angiogenesis dan modulasi imun. Scoping review ini bertujuan mengeksplorasi bukti terapi sel punca terkini pada tata laksana CLTI no-option dan efektivitasnya. Metode: Scoping review ini dilakukan sesuai dengan panduan Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA ScR). Penulusuran artikel dilakukan secara sistematis di lima database: Cochrane (CENTRAL), Scopus, PubMed, EBSCOhost, dan ProQuest. Kriteria inklusi adalah studi RCT dan observasional yang meneliti terapi sel punca pada pasien CLTI no-option. Studi terpilih dinilai risiko bias dan level of evidence. Hasil: Dari 245 studi yang diskrining, terpilih 11 artikel yang memenuhi kriteria eligibilitas (10 RCT, 1 non-randomized study). Bone marrow (BM) MSC diinjeksi secara intramuskular, dan satu studi menggunakan rute intraarteri. Dosis bervariasi dari 5,04 × 10⁶hingga 5,61×10⁹sel, termasuk dosis berdasarkan berat badan. Pemantauan dilakukan 1–24 bulan. Seluruh studi tetap mengerjakaan best supportive care. Perbaikan yang dilaporkan adalah nyeri saat istirahat (MD –0,23; –2,00), ankle-brachial index (MD 0,02; 0,20), tingkat amputasi (OR 0,13 – 0,85), dan penyembuhan ulkus (OR 1,52 – 7,78) disertai berkurangnya luas ulkus. Tidak ada mortalitas dan morbiditas yang dilaporkan. Kesimpulan: Sel punca mesenkimal memiliki potensi sebagai tata laksana regeneratif pada CLTI no-option, terlihat dari adanya berkurangnya nyeri dan perbaikan ABI. Namun, pengaruhnya terhadap tingkat amputasi dan penyembuhan ulkus masih belum konsisten. Tidak ada efek samping, morbiditas, atau mortalitas yang dilaporkan. Terbatasnya jumlah studi dan terkait heterogenitas, manfaat terapi sel punca belum dapat disimpulkan secara meyakinkan, sehingga masih membutuhkan studi lanjutan.

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Introduction: Chronic limb-threatening ischemia (CLTI) affects patients with rest pain due to arterial occlusion. Around 20% are classified as no-option CLTI, being ineligible for or unresponsive to revascularization. Stem cell therapy, particularly using mesenchymal stem cells (MSCs), offers a novel regenerative approach through angiogenesis and immunomodulation. This scoping review explores current evidence on stem cell therapy for no-option CLTI and its effectiveness in promoting revascularization. Methods: This scoping review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA ScR) guidelines. A systematic search was performed across five databases: Cochrane (CENTRAL), Scopus, PubMed, EBSCOhost, and ProQuest. Eligible studies included RCT and observational studies investigating stem cell therapy in patients with no-option CLTI. All selected studies were assessed using risk of bias tools and level of evidence criteria. Results: Of 245 studies screened, 11 met the eligibility criteria (10 RCTs, 1 non randomized study). Bone marrow (BM) MSCs were mainly delivered intramuscularly, with one study using an intra-arterialroute.Dosesrangedfrom5.04×10⁶to5.61×10⁹ cells, including weight-based regimens; follow-up lasted 1–24 months. All studies provided best supportive care. Most reported improvements in rest pain (MD –0.23 to 2.00), ankle-brachial index (MD 0.02 to 0.20), amputation rates (OR 0.13 to 0.85), and improved ulcer healing (OR 1.52 to 7.78) with ulcer area reduction. No studies reported mortality or morbidity outcomes. Conclusions: BM MSCs therapy shows potential as a regenerative treatment for no option CLTI, with consistent benefits observed in pain reduction and ABI improvement. However, its impact on amputation prevention and ulcer healing remains uncertain. No adverse events, including mortality or morbidity, were reported. Due to the limited number and heterogeneity of studies, current evidence is insufficient to draw definitive conclusions, underscoring the need for further robust clinical trials. "

"The prompt diagnosis of systemic vasculitis is essential as a missed diagnosis can be disastrous. Imaging is of vital importance in achieving a correct diagnosis and in some cases also plays a role in endovascular treatment. In this book, the imaging features of the many different types of vasculitis are clearly demonstrated by means of numerous high-quality illustrations. All relevant imaging modalities are considered, and key distinctive characteristics are highlighted. In addition, each chapter discusses the etiology, epidemiology, pathogenesis, clinical presentation, biology, and treatment of the vasculitis in question. This book is the result of cooperation between expert teams from a range of countries. The wealth of illustrations and informative clinical case studies will prove invaluable for all who may be confronted with these problematic disorders."

"Magnetic resonance angiography : principles and applications is a comprehensive text covering magnetic resonance angiography (MRA) in current clinical use. The first part of the book focuses on techniques, with chapters on contrast-enhanced MRA, time of flight, phase contrast, time-resolved angiography, and coronary MRA, as well as several chapters devoted to new non-contrast MRA techniques. Additionally, chapters describe in detail specific topics such as high-field MRA, susceptibility-weighted imaging, acceleration strategies such as parallel imaging, vessel wall imaging, targeted contrast agents, and low dose contrast-enhanced MRA. The second part of the book covers clinical applications of MRA, with each chapter describing the MRA techniques and protocols for a particular disease and vascular territory, as well as the pathology and imaging findings relevant to the disease state being discussed."

"The Handbook of endovascular peripheral interventions has been written to serve as a comprehensive guide for both the beginner and advanced interventionalist. Covering all aspects of percutaneous peripheral vascular interventions, each chapter of this highly illustrated book provides a brief background, etiology, clinical presentation, imaging, and percutaneous treatment of different vascular conditions. Importantly, tips of the trade and how i do it sections within each chapter make the handbook practical for daily use. These invaluable pearls are provided by contributing chapter authors who are experts in the field.The handbook of endovascular peripheral interventions is a collaborative effort between cardiologists, vascular surgeons, and radiologists. Since each subspecialty brings unique expertise and experience to the field, this handbook will be a valuable resource for all physicians currently working in peripheral vascular interventions."

"This book provides a thorough yet succinct and accessible review of the latest knowledge in the field of endovascular surgery. All chapters have been updated to reflect the advances that have occurred during the past five years, and new chapters are included on carotid artery stenting and day case intervention. The chapter on lower limb veno-occlusive disease has been expanded to include management of deep venous thrombosis. Among the other topics considered are the endovascular treatment options in different arterial territories, aneurysm repair techniques, and the management of venous stenosis and venous insufficiency. The aim throughout is to tackle issues of evidence-based practice in order to assist trainees and experienced practitioners in making and implementing treatment decisions. "