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Yudistira Prama Tirta
"ABSTRAK
Pendahuluan. Parameter spinopelvik merupakan parameter untuk mengukur
keseimbangan poros tulang belakang terhadap ekstrimitas bawah pada penampang
sagital. Parameter ini terdiri dari sagittal vertical axis (SVA), pelvic incidence
(PI), pelvic tilt (PT), pelvic incidence (PI) dan diukur melalui X-ray whole spine
lateral view dalam keadaan berdiri. Pengukuran parameter ini penting sebagai
dasar analisa keseimbangan sagital dalam operasi rekonstruktif tulang belakang,
karena dengan tidak adanya keseimbangan pada penampang sagital ini akan
berakibat timbulnya adjacent segment degeneration yang akan memengaruhi
luaran klinis. Hingga saat ini belum ada studi yang mengevaluasi hubungan antara
luaran parameter spinopelvik dengan luaran klinis di indonesia.
Metode Penelitian. Penelitian ini adalah penelitian analitik potong lintang dengan
subyek 19 pasien dewasa pasca operasi stabilisasi dan fusi tulang belakang torakal
dan lumbal di Rumah Sakit Dr. Ciptomangunkusumo (RSCM) Jakarta pada tahun
2012-2014. Pasien tersebut dilakukan evaluasi X-ray parameter spinopelvik SVA,
PI, PT, dan SS dilakukan penilaian skor Indeks Disabilitas Oswestry (IDO) pada
saat 1 tahun pasca operasi. Lalu dilakukan analisis statistik dengan menggunakan
uji hipotesis komparatif numerik dengan menggunakan pearson dimana
dibandingkan luaran parameter spinopelvik SVA, PI, PT, dan SS dengan luaran
fungsional skor IDO.
Temuan dan Diskusi Penelitian. Didapatkan hasil korelasi antara IDO dan SVA
(p<0,001) (r=0,866). Korelasi antara IDO dan PI (p=0,006) (r=0,603). Korelasi
antara IDO dan PT (p=0,107) (r=0,382). Korelasi IDO dan SS (p=0,051)
(r=0,454).
Simpulan. Didapatkan korelasi kuat antara IDO dan SVA serta IDO dan PI.
Tidak didapatkan korelasi antara IDO dan PT serta IDO dan SS. SVA dan PI
merupakan parameter spinopelvik yang berpengaruh pada luaran pasca operasi fusi tulang belakang torakal dan lumbal.
ABSTRACT
Introduction. Spinopelvic parameter is a parameter that used to measure the
sagital balance of vertebrae in congruency with lower extrimity in sagital plane.
This parametr is consist of sagittal vertical axis (SVA), pelvic incidence (PI),
pelvic tilt (PT), pelvic incidence (PI) dan diukur melalui X-ray whole spine lateral
view in standing position. Measurement of this parameter is important as basic
analysis for achieve sagital balance in reconstructive operation of the vertebrae,
because if the sagital balance is interupted will cause the adjacent segment
degeneration that will influence the clinical outcomes. Up until now, there is no
study that evaluate the spinopelvic parameter with the clinical outcomes in
Indonesia.
Methods. This study is a cross-sectional analytic with 19 subject of adult patient
that had undergo thoracal and lumbar fusion and stabilization in Rumah Sakit Dr.
Ciptomangunkusumo (RSCM) Jakarta in 2012-2014. The subject was underwent
x-ray evaluation of SVA, PI, PT, and SS. The patient also underwent evaluation
of Indeks Disabilitas Oswestry (IDO) score in 1 year after operation. Then the
statistical work was done with numeric comparative pearson test analysis to
determine whether there is correlation between SVA, PI, PT, and SS with IDO
score.
Result and Discussion. There is strong correlation between IDO and SVA
(p<0,001) (r=0,866). Strong correlation between IDO and PI (p=0,006) (r=0,603).
No correlation between IDO and PT (p=0,107) (r=0,382). No correlation between
IDO and SS (p=0,051) (r=0,454).
Conclusion. Strong correlation is indicated in IDO and SVA, also in IDO and PI.
There is no correlation between IDO and PT, also in IDO and SS. SVA and PI are
the important spinopelvic parameter that have influence on clinical outcome in
post thoracal and lumbar fusion and stabilization patient.
;Introduction. Spinopelvic parameter is a parameter that used to measure the
sagital balance of vertebrae in congruency with lower extrimity in sagital plane.
This parametr is consist of sagittal vertical axis (SVA), pelvic incidence (PI),
pelvic tilt (PT), pelvic incidence (PI) dan diukur melalui X-ray whole spine lateral
view in standing position. Measurement of this parameter is important as basic
analysis for achieve sagital balance in reconstructive operation of the vertebrae,
because if the sagital balance is interupted will cause the adjacent segment
degeneration that will influence the clinical outcomes. Up until now, there is no
study that evaluate the spinopelvic parameter with the clinical outcomes in
Indonesia.
Methods. This study is a cross-sectional analytic with 19 subject of adult patient
that had undergo thoracal and lumbar fusion and stabilization in Rumah Sakit Dr.
Ciptomangunkusumo (RSCM) Jakarta in 2012-2014. The subject was underwent
x-ray evaluation of SVA, PI, PT, and SS. The patient also underwent evaluation
of Indeks Disabilitas Oswestry (IDO) score in 1 year after operation. Then the
statistical work was done with numeric comparative pearson test analysis to
determine whether there is correlation between SVA, PI, PT, and SS with IDO
score.
Result and Discussion. There is strong correlation between IDO and SVA
(p<0,001) (r=0,866). Strong correlation between IDO and PI (p=0,006) (r=0,603).
No correlation between IDO and PT (p=0,107) (r=0,382). No correlation between
IDO and SS (p=0,051) (r=0,454).
Conclusion. Strong correlation is indicated in IDO and SVA, also in IDO and PI.
There is no correlation between IDO and PT, also in IDO and SS. SVA and PI are
the important spinopelvic parameter that have influence on clinical outcome in
post thoracal and lumbar fusion and stabilization patient.
"
Fakultas Kedokteran Universitas Indonesia, 2015
SP-PDF
UI - Tugas Akhir  Universitas Indonesia Library
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Marpaung, Madeline F.N.
"[ABSTRAK
Latar belakang. Penyuntikan berulang pada prosedur anestesia spinal berkaitan dengan tingginya angka komplikasi dan ketidaknyamanan pasien. Sistem prediksi praoperatif yang akurat terhadap kemungkinan kesulitan penempatan jarum spinal dapat membantu mengurangi insiden penyuntikan berulang sehingga mengurangi risiko komplikasi terhadap pasien. Penelitian ini bertujuan untuk mengetahui ketepatan prediksi kesulitan penempatan jarum spinal berdasarkan gambaran radiologis dan penanda anatomis pada pasien bedah urologi.
Metode. Penelitian ini bersifat observasional analitik terhadap pasien bedah urologi yang menjalani anestesia spinal di Rumah Sakit Cipto Mangunkusumo pada bulan April sampai Mei 2015. Sebanyak 109 subyek diambil dengan metode consecutive sampling. Data pasien (usia, jenis kelamin, indeks massa tubuh, status fisik, gambaran radiologis vertebrae lumbal, dan kualitas penanda anatomis tulang belakang), jumlah penusukan kulit dan redireksi jarum spinal, serta angka kesulitan penempatan jarum spinal dicatat. Kesulitan penempatan jarum spinal ditentukan berdasarkan jumlah penusukan kulit dan redireksi jarum spinal. Variabel yang signifikan ditentukan melalui uji Pearson?s Chi-square dan uji Fisher, kemudian analisis multivariat dengan metode regresi logistik digunakan untuk melihat hubungan antara kesulitan penempatan jarum spinal dengan variabel-variabel yang signifikan.
Hasil. Faktor usia memiliki hubungan yang bermakna hanya pada analisis bivariat (p=0,028). Kualitas penanda anatomis dan gambaran radiologis vertebrae lumbal memiliki nilai prediksi terhadap kesulitan penempatan jarum spinal (p=0,000 dan p=0,006). Hasil uji kalibrasi menunjukkan kualitas prediksi yang baik. Dari uji diskriminasi didapatkan AUC sebesar 0,84 (IK 95% 0,751-0,929).
Simpulan. Kualitas penanda anatomis dan gambaran radiologis vertebrae lumbal mampu memprediksi kesulitan penempatan jarum spinal dengan tepat pada pasien bedah urologi. ABSTRACT Background. Multiple attempts at spinal puncture have been related to many complications and patient discomfort. Accurate preoperative prediction of spinal needle insertion difficulty would reduce the incidence of multiple puncture and minimize the complications consequently. This study was designed to determine the accuracy of lumbar vertebrae radiological characteristics and spinal bony landmark quality in predicting the difficulty of spinal needle insertion in patients undergoing urologic procedure.
Methods. This was an analytic observational study in urologic patients scheduled for spinal anesthesia at Cipto Mangunkusumo hospital between April and May 2015. A total of 109 subjects were included in the study by consecutive sampling. Patient data (age, sex, body mass index, physical status, radiological characteristics of the lumbar vertebrae, and quality of spinal bony landmark), number of skin puncture and needle redirection, and the prevalence of spinal needle insertion difficulty were recorded. The first skin puncture success and number of needle redirection were used to assess the difficulty. Significant variables were first determined by Pearson?s Chi-square and Fisher test, and then multivariate analysis using logistic regression method tested the association of the skin puncture success and number of needle redirection with the significant variables.
Results. Age was significant only in bivariate analysis (p=0,028). The quality of spinal bony landmark and the radiological characteristics of the lumbar vertebrae had predictive value on spinal needle insertion difficulty (p=0,000 and p=0,006 respectively). Calibration test showed that the prediction quality was good. The discrimination test resluted in AUC of 0,84 (CI 95% 0,751 to 0,929).
Conclusion. The quality of spinal bony landmark and the radiological characteristics of the lumbar vertebrae were accurate in predicting the difficulty of spinal needle insertion in patients undergoing urologic procedure. ;Background. Multiple attempts at spinal puncture have been related to many complications and patient discomfort. Accurate preoperative prediction of spinal needle insertion difficulty would reduce the incidence of multiple puncture and minimize the complications consequently. This study was designed to determine the accuracy of lumbar vertebrae radiological characteristics and spinal bony landmark quality in predicting the difficulty of spinal needle insertion in patients undergoing urologic procedure.
Methods. This was an analytic observational study in urologic patients scheduled for spinal anesthesia at Cipto Mangunkusumo hospital between April and May 2015. A total of 109 subjects were included in the study by consecutive sampling. Patient data (age, sex, body mass index, physical status, radiological characteristics of the lumbar vertebrae, and quality of spinal bony landmark), number of skin puncture and needle redirection, and the prevalence of spinal needle insertion difficulty were recorded. The first skin puncture success and number of needle redirection were used to assess the difficulty. Significant variables were first determined by Pearson?s Chi-square and Fisher test, and then multivariate analysis using logistic regression method tested the association of the skin puncture success and number of needle redirection with the significant variables.
Results. Age was significant only in bivariate analysis (p=0,028). The quality of spinal bony landmark and the radiological characteristics of the lumbar vertebrae had predictive value on spinal needle insertion difficulty (p=0,000 and p=0,006 respectively). Calibration test showed that the prediction quality was good. The discrimination test resluted in AUC of 0,84 (CI 95% 0,751 to 0,929).
Conclusion. The quality of spinal bony landmark and the radiological characteristics of the lumbar vertebrae were accurate in predicting the difficulty of spinal needle insertion in patients undergoing urologic procedure. , Background. Multiple attempts at spinal puncture have been related to many complications and patient discomfort. Accurate preoperative prediction of spinal needle insertion difficulty would reduce the incidence of multiple puncture and minimize the complications consequently. This study was designed to determine the accuracy of lumbar vertebrae radiological characteristics and spinal bony landmark quality in predicting the difficulty of spinal needle insertion in patients undergoing urologic procedure.
Methods. This was an analytic observational study in urologic patients scheduled for spinal anesthesia at Cipto Mangunkusumo hospital between April and May 2015. A total of 109 subjects were included in the study by consecutive sampling. Patient data (age, sex, body mass index, physical status, radiological characteristics of the lumbar vertebrae, and quality of spinal bony landmark), number of skin puncture and needle redirection, and the prevalence of spinal needle insertion difficulty were recorded. The first skin puncture success and number of needle redirection were used to assess the difficulty. Significant variables were first determined by Pearson’s Chi-square and Fisher test, and then multivariate analysis using logistic regression method tested the association of the skin puncture success and number of needle redirection with the significant variables.
Results. Age was significant only in bivariate analysis (p=0,028). The quality of spinal bony landmark and the radiological characteristics of the lumbar vertebrae had predictive value on spinal needle insertion difficulty (p=0,000 and p=0,006 respectively). Calibration test showed that the prediction quality was good. The discrimination test resluted in AUC of 0,84 (CI 95% 0,751 to 0,929).
Conclusion. The quality of spinal bony landmark and the radiological characteristics of the lumbar vertebrae were accurate in predicting the difficulty of spinal needle insertion in patients undergoing urologic procedure. ]"
Fakultas Kedokteran Universitas Indonesia, 2015
SP-PDF
UI - Tugas Akhir  Universitas Indonesia Library
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Ricky Roosdiana Dewi
"LSTV merupakan variasi vertebra yang prevalensinya bervariasi di dunia. Menurut konsep Bertolotti rsquo;s syndrome, LSTV berhubungan dengan nyeri punggung bawah dan sebagian besar nyeri ini disebabkan oleh penyakit degenerasi diskus. Sayangnya, hubungan keduanya masih kontroversial. Pada penelitian ini dilakukan analisis hubungan LSTV dengan penyakit degenerasi diskus lumbosakral berdasarkan gambaran CT scan. Penelitian menggunakan desain potong lintang dengan jumlah sampel 161 pasien. Data sampel diambil dari database sekunder CT scan abdomen di Departemen Radiologi RSUPNCM dengan berbagai indikasi klinis dan dianalisis menggunakan uji statistik chi-square. Hasilnya, sebanyak 25,5 individu yang diidentifikasi memiliki LSTV dan sebanyak 77,0 individu mengalami degenerasi diskus lumbosakral. Meskipun begitu, uji hipotesis menunjukkan tidak terdapat hubungan bermakna antara LSTV dengan penyakit degenerasi diskus lumbosakral p>0,05.

LSTV is one of vertebra variation which has variation prevalent in the world. Based on Bertolotti rsquo s syndrome concept, LSTV is suggested related to low back pain and most of this pain is come from degeneretaive disc disease. Unfortunately, Bertolotti rsquo s syndrome concept is still debated around the world. This research will analyze the relationship between LSTV and degenerative lumbosacral disc disease based on CT Scan imaging. The research use cross sectional design with 161 samples. The data used were collected from abdominal seconday CT scan database in Radiology Department in RSUPNCM with any clinical indications and analyzed using chi square test. The result shows 25,5 subject has LSTV and 77,0 subject has degenerative lumbosacral disc disease. Although, hypothesis test shows that there is no significant relationship between LSTV and degenerative disc disease p 0,05.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2016
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UI - Skripsi Membership  Universitas Indonesia Library
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Harryanto Wijaya
"ABSTRAK
Identifikasi fase pacu tumbuh pubertas penting untuk meningkatkan efisiensi dan efektifitas perawatan maloklusi. Tujuan penelitian ini untuk menganalisis potensi kadar Bone-Specific Alkaline Phosphatase BALP saliva dan parameter klinis sebagai prediktor fase pacu tumbuh pubertas dengan memperhatikan berbagai faktor tumbuh kembang skeletal. Penelitian diagnostik dengan sampel 136 orang ini menggunakan metode Cervical Vertebrae Maturation System CVMS Bacceti sebagai baku emas. Melalui analisis regresi multinomial dihasilkan model prediksi dengan nilai sensitifitas 78 untuk fase pra-puncak dan 57,7 untuk fase puncak, sedangkan nilai spesifisitas fase pasca-puncak 81,4 . Fase pacu tumbuh pubertas terutama pra-puncak dan pasca-puncak dapat diprediksi menggunakan kadar BALP saliva dan parameter klinis.

ABSTRACT
The identification of growth spurt phase of puberty is important as it enhances the efficiency and effectiveness of malocclusion treatment. The objective of this study was to analyse the potential of the level of salivary Bone Specific Alkaline Phosphatase BALP and clinical parameters as a predictor of growth spurt phase of puberty by taking into account various factors affecting skeletal growth. The diagnostic test with the sample of 136 people was conducted by using the method of Cervical Vertebrae Maturation System CVMS from Bacceti as the gold standard. Multinomial regression analysis produced predictive models with 78 sensitivity at the pre peak phase and 57.7 at the peak phase, whereas the specificity of post peak phase was 81.4 . The growth spurt phase of puberty especially at the phases of pre peak and post peak can be predicted by using salivary BALP level and clinical parameters."
2017
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UI - Disertasi Membership  Universitas Indonesia Library
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Karmila Putri Maulidya
"Gangguan pada Vertebrae yang umum terjadi berupa Disc Degenerative Disease (DDD) dimana intervertebral disc atau diskus tulang belakang mengalami kerusakan dan tidak dapat menopang vertebrae sesuai fungsinya. Pengobatan terhadap DDD dapat dilakukan secara konservatif dengan terapi dan obat-obatan, maupun secara operatif dengan mengganti intervertebral disc. Terdapat beberapa metode operasi pemasangan implan yang masing-masing memiliki cara insersi berbeda. Di antara metode insersi tersebut, TLIF merupakan metode dengan tingkat invasi paling minimum dan dapat diminimalkan lagi dengan menerapkan prinsip Minimally Invasive Spine Surgery (MISS). Prinsip ini bertujuan untuk memperkecil ukuran sayatan operasi pada saat insersi implan, dapat dilakukan dengan bantuan teknologi atau dengan modifikasi geometri implan. Penelitian ini akan mengembangkan desain geometri implan TLIF menjadi modular lepas pasang dengan sistem pengunci horizontal dan vertikal. Bagian modular perlu diuji keberhasilannya menggunakan prototipe hasil fabrikasi stereolithography (SLA) maupun Fused Deposition Modelling (FDM). Desain implan kemudian dimanufaktur dengan material PEEK untuk dilakukan pengujian simulasi Metode Elemen Hingga dan eksperimental kompresi. Geometri modular memiliki pengaruh menurunkan kekuatan mekanik implan dibandingkan geometri nonmodular. Akan tetapi penurunan kekuatan tersebut masih pada batas aman kemampuan mekanik yang dibutuhkan oleh implan. Oleh karena itu, dengan dikembangkannya desain geometri modular ini, prinsip MISS dapat dicapai dan kekuatan mekanik yang dibutuhkan tetap dapat dicapai oleh implan TLIF.

Disorders of the Vertebrae commonly occurs is Disc Degenerative Disease (DDD) in which the intervertebral discs or spinal discs are damaged and cannot support the vertebrae according to their function. Treatment of DDD can be done conservatively with therapy and drugs, or operatively by replacing the intervertebral disc. There are several surgical implant methods, each of which has a different way of insertion. Among these insertion methods, TLIF is the method with the minimum level of invasion and can be minimized by applying the principles of Minimally Invasive Spine Surgery (MISS). This principle aims to reduce the size of the surgical incision at the time of implant insertion, which can be done with the help of technology or by modifying the implant geometry. This research will develop the geometry design of TLIF implants into a detachable modular system with a horizontal and vertical locking system. Modular parts are required to be tested for success using prototypes produced by 3-dimensional stereolithography (SLA) printing and Fused Deposition Modeling (FDM). The implant design was then manufactured with PEEK material for the Finite Element Method simulation and compression experimental tests. Modular geometry has the effect of reducing the mechanical strength of the implant compared to non-modular geometry. However, this decrease in power is still within the safe limits of the mechanical capabilities required by the implant. Therefore, with the development of this modular geometry design, the MISS principle can be achieved and TLIF implants can still achieve the required mechanical strength."
Depok: Fakultas Teknik Universitas Indonesia, 2023
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UI - Skripsi Membership  Universitas Indonesia Library
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Jessica Dean Indah Ayyu
"Latar Belakang: Memprediksi tahap pertumbuhan struktur kraniofasial dapat menjadi tantangan pada subjek dengan pola wajah yang berbeda. Maturasi vertebra servikalis merupakan salah satu indikator dalam menentukan tahap pertumbuhan. Perbedaan waktu tercapainya tahap maturasi dianggap berkaitan dengan karakteristik intrinsik pertumbuhan vertikal wajah dengan pola dimensional yang berbeda. Tujuan: Mengetahui distribusi tahap maturasi vertebra servikalis berdasarkan pola vertikal wajah dan perbedaan usia tercapainya tahap pubertal pada subjek perempuan dengan pola vertikal wajah yang berbeda. Metode: Studi deskriptif dan analitik komparatif retrospective cross sectional pada pasien di Klinik Ortodonti RSKGM FKG UI. Tracing dilakukan pada sefalometri lateral untuk mengetahui pola vertikal wajah berdasarkan sudut SN-GoGn dan tahap maturasi vertebra servikalis dengan analisa Baccetti et al. (2005). Hasil: Terdapat perbedaan bermakna rata-rata usia tercapainya tahap pubertal pada subjek perempuan antara pola vertikal wajah hipodivergen dengan hiperdivergen dan normodivergen, namun tidak terdapat perbedaan bermakna rata-rata usia antara subjek dengan pola hiperdivergen dan normodivergen. Secara klinis, ditemukan bahwa subjek dengan pola vertikal wajah hiperdivergen mencapai tahap pubertal paling cepat, diikuti pola normodivergen, dan kemudian hipodivergen. Kesimpulan: Terdapat perbedaan rata-rata usia kronologis tercapainya tahap pubertal maturasi vertebra servikalis pada subjek perempuan dengan pola vertikal wajah yang berbeda.

Background: Predicting the craniofacial growth could be a challenge in subjects with different facial pattern. Cervical vertebrae maturation method can be used to determine an individual growth stage. The different time of attainment of a maturation stage is considered to be related to intrinsic characteristic of a vertical facial growth with different dimensional pattern. Objective: To determine the distribution of cervical vertebrae maturation in different vertical facial pattern and assess the difference in age of attainment of pubertal stage in different vertical facial pattern in female. Method: Retrospective cross sectional study is done on patients at RSKGM FKG UI Orthodontic Clinic. Cephalometric lateral radiograph is traced to determine vertical facial pattern based on SN-GoGn angle and cervical vertebrae maturation stage with the analysis of Baccetti et al. (2005). Result: Statistical analysis showed significant difference between the age of attainment of pubertal stage in female subjects with hypodivergent with hyperdivergent and normal vertical facial pattern, while no significant difference was found between hyperdivergent and normal vertical facial pattern. Clinically, hyperdivergent female subjects found to be the earliest to attain pubertal stage, followed by normal, then hypodivergent vertical facial pattern. Conclusion: Female subject’s mean age of attainment of pubertal stage in cervical vertebrae maturation differ according to vertical facial pattern."
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2022
S-pdf
UI - Skripsi Membership  Universitas Indonesia Library