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Daruqutni
"ABSTRAK
Vasektomi sudah diterima masyarakat sebagai metode yang mudah dan efektif untuk kontrasepsi pria. Namun, beberapa pasien ingin mengembalikan kesuburan mereka karena kasus perceraian atau pernikahan kembali. Teknik melakukan vasektomi reversal bervariasi dengan kelebihan dan kekurangannya. Salah satu teknik adalah vasektomi reversal mikroskopik double layer. Kami mengevaluasi tingkat keberhasilan teknik ini didasarkan pad analisis semen. Tingkat keberhasilan baik yaitu sekitar 98,5 pasien dengan tindak lanjut lengkap memiliki sperma berdasarkan analisis sperma. Namun, total keberhasilan tindak lanjut sangat rendah 5 dari 19 pasien meskipun biaya vasektomi reversal cukup mahal sekitar 3.000 USD . Tingkat lost follow up pada vasektomi reversal adalah sekitar 20 .

ABSTRACT
Vasectomy already been accepted by the society as easy and effective method formale contraceptive. However, some patients want to restore their fertility status due to divorce or re marriage cases. Techniques in performing vasectomy revUrologiersal are varying with their own advantages and disadvantages. One of the techniques is double layer microscopy vasectomy reversal. We evaluate the success rate of this technique based on the semen analysis. The success rate was good with around 98.5 patients with complete follow up had sperm in their semen analysis However, total success of follow up were very low 5 out of 19 patients even though the cost of reversal vasectomy was quite expensive around 3.000 USD . Lost to follow up rate of reversal vasectomy was around 20 ."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2016
T58746
UI - Tesis Membership  Universitas Indonesia Library
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hapus3
"ABSTRACT
Aim: to detect Y-chromosomal microdeletion in Indonesian men with azoospermia or severe oligozoospermia using multiplex PCR. Methods: we performed 2 multiplex PCR amplifications of the Azoospermia Factor (AZF) region in 71 men. Criteria for including a patient were fulfilled if they presented with azoospermia or severe oligozoospermia, with or without additional abnormalities of sperm motility or of head morphology, raised or normal levels of FSH, normal levels of LH and testosterone, and with no evidence of testicular tumors or other abnormalities. Five men participated as control persons. Results: partial deletion of AZFa was found in 11 men (15.49%), complete deletion of AZFb in 1 man (1.4%), and complete deletion of AZFc in 1 man (1.4%). The unspecific type of deletion was also detected, including the DBY gene in 2 men (2.81%), and partial deletion of both AZFa and AZFb in 2 men (2.81%). No AZF deletion was observed in the control probands. Related to the type of deletion, the AZFa and AZFb deletion showed spermatogenesis arrest in most tubules, while deletion of the DBY gene is associated with the sertoli cell only (SCO) syndrome. Conclusion: the frequency of partial deletion of AZFa was found to be relatively high in our center. The type of deletion is associated with the testicular histology.
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Jakarta: University of Indonesia. Faculty of Medicine, 2017
610 UI-IJIM 49:1 (2017)
Artikel Jurnal  Universitas Indonesia Library
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Hervita Diatri
"Komorditas risiko kardiometabolik pada ODS lebih besar dibandingkan populasi umum dan menyebabkan mortalitas tinggi di usia produktif. Berbagai modalitas tata laksana untuk masalah kesehatan tersebut tersedia di fasilitas primer hingga tersier. Sayangnya, akses layanan yang terpadu dan bermutu belum ada di Indonesia. Penelitian ini bertujuan untuk mengembangkan model layanan terpadu tersebut di fasilitas kesehatan primer di Indonesia. Penelitian ini menggunakan model pengembangan sistem spiral yang mengikuti tiga tahap action research. Tahap pertama menggabungkan metode kuantitatif desain potong lintang studi komparatif dan kualitatif observasi, penelusuran kepustakaan, wawancara mendalam, dan lokakarya untuk mengidentifikasi masalah, gambaran pelayanan, dan potensi penyelesaian masalah sebagai dasar pengembangan model layanan terpadu. Subjek penelitian kuantitatif pada tahap ini adalah ODS usia 18-59 tahun yang menjalani pengobatan di 20 puskesmasprovinsi DKI Jakarta. Data kualitatif berasal dari ODS, keluarga, penyedia layanan, akademisi, dan pemangku kebijakan di daerah maupun pusat. Model awal dikembangkan berdasarkan modifikasi terhadap clinical pathway dari WHO-PEN Package of essential noncommunicable disease interventions . Kemamputerapan dan kebutuhan penyesuaian model dinilai berdasarkan hasil identifikasi solusi. Model layanan terpadu yang dikembangkan, kemudian diujicobakan dan dinilai secara kuantitatif dan kualitatif di tahap kedua untuk melihat kemampulaksanaan melalui ketersediaan layanan, kesesuaian penerapan, dan kesediaan tenaga kesehatan untuk melanjutkan layanan. Evaluasi dampak model layanan melalui desain eksperimental kuasi dinilai melalui efektivitas terhadap parameter klinis dan nonklinis. Proporsi ODS dengan risiko kardiometabolik adalah 88 dari 216 partisipan ODS , dan hanya 6,8 yang mendapatkan akses layanan komorbiditas. Data kuantitatif maupun kualitatif menunjukkan bahwa para pemangku kepentingan berharap akan model layanan terpadu dapat dikembangkan di puskesmas 63,7 , menggunakan berbagai sumber daya yang telah ada, melibatkan tim 61,1 , ditekankan pada upaya skrining dan pemantauan berkala 59,5 . Model layanan terpadu dalam bentuk clinical pathway maupun alur layanan ternyata tidak dapatditerapkan sepenuhnya di puskesmas karena masalah ketersediaan layanan, infrastruktur, keberadaan tenaga kesehatan, sistem komunikasi antar tenaga kesehatan, dan budaya kerja, serta faktor pasien dan keluarga. Namun demikian > 79 tenaga kesehatan yang terlibat bersedia untuk melanjutkan penerapan alur layanan. Model layanan efektif memperbaiki kadar kolesterol-HDL darah, tetapi untuk parameter tekanan darah, lingkar pinggang, kadar glukosa, trigliserida darah menunjukkan hasil tidak berbeda bermakna antara kelompok intervensi dan kelompok kontrol. Evaluasi parameter nonklinis yang menunjukkan hasil bermakna terbatas pada tingkat aktivitas fisik ODS, tetapi tidak untuk variabel pola diet, pengetahuan, dan kepuasan pasien. Model layanan luar gedung yang pengaturannya terpisah dari tata laksana kegiatan puskesmas dan model layanan dalam gedung yang terpisah antara layanan penyakit tidak menular PTM dan layanan jiwa, adalah sebab utama kurang mampu laksananya model yang diujikan. Proses skrining dan pemantauan berkala perlu dilakukan pada semua ODS sebagai awal akses layanan. Peningkatan pengetahuan dan keterampilan ODS dan keluarga penting untuk meningkatkan kapasitas partisipatif, sedangkan bagi tenaga kesehatan diperlukan untuk manajemen risiko melalui skrining dan pemantauan berkala. Pengembangan tim terpadu PTM dan jiwa baik untuk kegiatan di dalam maupun luar gedung diharapkan dapat memudahkan kerja tim untuk mengatasi hambatan kesinambungan penyediaan layanan, infrastruktur, dan kesulitan akses ODS sehingga efektivitas layanan semakin baik.

Cardiometabolic comorbidity is higher in people with schizophrenia than in general population and this caused high mortality in productive age. A variety of management modalities for this specific health problem are available in primary to tertiary health facilities. Unfortunately, high quality and accessible comprehensive service did not exist in Indonesia. This research aimed to develop an integrated service in primary health facilities for PwS and cardiometabolic risks in public health centers in Indonesia.Using the spiral model of system development, this research followed the three phase of action research. The first phase combined quantitative comparative cross-sectional study and qualitative observation, literature review, in-depth interview, and workshop methods to identify problems, health service condition, and potential solutions as a basis for developing an integrated service model. Subjects for the quantitative research in this phase were PwS who were at the age of 18-59 years old who underwent treatment in 20 public health centers in Jakarta Special Capital Region. Qualitative data came from PwS, their families, academia, and policy makers at national and sub-national levels. Early model was developed based on modification to the WHO-PEN Package of essential noncommunicable disease interventions clinical pathway. Implementability and needs for model adjustments were evaluated from the result of solutions identification. The developed comprehensive service model was tested and evaluated quantitative and qualitatively in the second phase to see if it is feasible by means of availability of services, suitability of implementation, and availability of health workers to continue the service. Evaluation on the impact of the service model was done through quasi-experimental design to evaluate its efficacy using clinical and non-clinical parameters. Proportion of PwS with cardiometabolic risks was 88 from 216 PwS participants , from which only 6.8 had access to service for comorbidities. Quantitative and qualitative data showed that stake-holders would like to see that this integrated service model can be implemented in primary health care service PHCs 63.7 , using various existing resources, involving team approach 61.1 , and stressing on screening and periodic monitoring 59.5 . An integrated service model in the form of clinical pathway or service algorithm could not be fully implemented because of problems with service availability, infrastructures, availability of health workers, communication system among health workers, working culture, patient and family factors. In spite of that, more than 79 of health workers who were involved in the research are willing to continue implementing the service pathway. This service model was proven to be effective in controlling blood HDL-cholesterol level, but failed to show significant differences in blood pressure, waist circumference, blood glucose, and triglyceride between intervention and control groups. Evaluation on non-clinical parameters showed limited meaningful results on level of physical activities, but not on diet pattern, knowledge, and satisfaction. Extramural model, which separated arrangement from management activities in the PHC and disintegration intramural services between Non-communicable diseases NCDs and mental health services, was the main reason for the lack of efficacy in the tested model. Screening and periodic monitoring should be done for all PwS as initial access to service. Improvement of knowledge and skills of PwS and their families is important in increasing their participatory capacity and for health workers to be able to manage risks through screening and periodic monitoring. It is expected that the development of an integrated non-communicable disease and psychiatric team, intra and extra-mural of PHCs, could overcome the barriers of continuous provision of service, infrastructure, and access of PwS."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2018
D-Pdf
UI - Disertasi Membership  Universitas Indonesia Library