Ditemukan 14 dokumen yang sesuai dengan query
Ari Wibisono, author
Molecular dynamic simulation is one field of science that uses computer as a resource for computational methods to calculate the number of forces acting within a molecular system and analyzing its movement. This simulation is useful for the discovery of drug compounds from an illness. This study uses Gromacs as...
ICACSIS, 2010
MK-Pdf
UI - Makalah dan Kertas Kerja Universitas Indonesia Library
Muhammad Hafizhuddin Hilman, author
2010
MK-Pdf
UI - Makalah dan Kertas Kerja Universitas Indonesia Library
Heru Suhartanto, author
ABSTRACT
One of the processes requiring HPC environments is Molecular Dynamics ( MD ) . In tropical countries, the MD process is very important in the preparation of virtual screening experiments for anti-malaria search. Previous works on the virtual screening project for anti-malaria search conducted by WISDOM project uses...
2014
MK-Pdf
Artikel Jurnal Universitas Indonesia Library
Indri Indrawan, author
As a prolactin antagonist, dopamine binds to its receptor D2 and suppresses the secretion of prolactin
from the pituitary gland. Required ligand that can interact with receptor so that dopamine can no
longer bound to its receptor. Ligands empirically derived from plants and have been proven to
increase human lactation. In silico study...
2013
MK-Pdf
UI - Makalah dan Kertas Kerja Universitas Indonesia Library
Aries Fitriawan, author
ABSTRACT
Virtual screening (VS) is a computational technique used in drug discovery. Virtual Screening process usually works by identifying structures that are most likely to bind the target of drug. Virtual screening is usually based on compound similarity or database docking. Thus, the identification for drug
compounds based on structure classification still...
2016
MK-Pdf
UI - Makalah dan Kertas Kerja Universitas Indonesia Library
Marvi Nurjanah, author
ABSTRACT
Xylitol is a five-carbon polyol sugar. It has many healthy benefits and is widely used in food, pharmaceutical, and healthcare. Natural sources with abundant carbon such as lignocellulose can be used for xylitol production. One of the potencial sources with high prevalency in Indonesia is water hyacinth. It is known...
2013
MK-Pdf
UI - Makalah dan Kertas Kerja Universitas Indonesia Library
Luthfiyyah Mutsnaini, author
ABSTRACT
Xylitol is five-carbon polyol sugar which widely used as a sweetener in food and pharmaceutical.
Xylitol production by chemical procedures using high pressure and temperature also needed
extensive purification are less cost-effective in production. Fermentation which has more advantages
with lower cost due tocheaper substrate and the non-necessity of xylose purification. The purposes...
2013
MK-Pdf
UI - Makalah dan Kertas Kerja Universitas Indonesia Library
Heru Suhartanto, author
2014
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Artikel Jurnal Universitas Indonesia Library
Azminah, author
Sirtuin 1 (SIRT1) adalah famili kelas III dari protein histon deasetilasi (HDAC) dan reaksinya bergantung dengan NAD+. Aktivator SIRT1 menyerupai pembatasan kalori merupakan pendekatan terapi untuk diabetes mellitus tipe 2. Pencarian obat dapat dilakukan dengan metode in silico untuk mempercepat dan memfasilitasi identifikasi kandidat senyawa terbaik dan karakteristik fisikokimia dan...
Depok: Fakultas Farmasi Universitas Indonesia, 2020
D2810
UI - Disertasi (Membership) Universitas Indonesia Library
Heru Suhartanto, author
ABSTRACT
Molecular Dynamics (MD) is one of processes that requires High Performance Computing
environments to complete its jobs. In the preparation of virtual screening experiments, MD is one of
the important processes particularly for tropical countries in searching for anti-Malaria drugs. The
search for anti-Malaria has previously conducted, for example by WISDOM project utilizing...
2015
MK-Pdf
Artikel Jurnal Universitas Indonesia Library
