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Cynthia Utami
Abstrak :
ABSTRAK
Latar belakang: Fokus terapi asma adalah mencapai terkendalinya asma secara adekuat. Childhood Asthma Control Test (CACT) merupakan kuesioner penilaian terkendalinya asma pada anak yang cepat dan mudah digunakan. Penggunaan CACT di Indonesia masih terbatas karena kendala bahasa dan budaya. Sampai saat ini belum ada kuesioner CACT versi Indonesia (terjemahan CACT ke dalam bahasa Indonesia) yang terbukti sahih dan andal. Tujuan: Mengetahui kesahihan (validity) dan keandalan (reliability) kuesioner CACT versi Indonesia. Metode: Menerjemahkan tujuh pertanyaaan kuesioner CACT menjadi kuesioner CACT versi Indonesia. Studi potong lintang dilakukan terhadap 66 subjek usia 4-11 tahun yang dipilih secara konsekutif. Semua subjek menjalani uji fungsi paru dan pemeriksaan peak expiratory flow berkala. Analisis statistik menggunakan uji Cronbach?s  dan uji korelasi Pearson/ Spearman. Hasil: Rerata usia subjek penelitian adalah 7,89 tahun (5,25 -11,83 tahun) dengan proporsi jenis kelamin lelaki lebih tinggi dibandingkan anak perempuan. Sebagian besar subjek penelitian yaitu 60,4% memiliki status asma tidak terkendali (nilai kuesioner CACT ≤19). Kuesioner CACT versi Indonesia mempunyai keandalan (Cronbach?s  0,762) dan kesahihan konstruksi (r= 0,384-0,545) yang baik.Tidak terdapat korelasi bermakna antara kuesioner CACT versi Indonesia dengan nilai FEV1 (r =-0,024; p=0,846) dan nilai variabilitas mingguan PEF (r=-0,218; p=0,079). Simpulan: Kuesioner CACT versi Indonesia mempunyai kesahihan dan keandalan yang baik untuk menilai terkendalinya asma. Kuesioner ini tidak mempunyai korelasi dengan uji fungsi paru sehingga CACT tidak dapat menggantikan peran uji fungsi paru sebagai salah satu komponen penilaian terkendalinya asma.
ABSTRACT
Background: The goal of asthma treatment is to achieve control over the asthma adequately. The Childhood Asthma Control Test (CACT) is a quick and easy-touse questionnaire for assessing asthma control on children. The usage of CACT in Indonesia is limited due to the language and culture barrier. To date, there is no Indonesian version of CACT questionnaire that is proven to be reliable and valid. The aim of this study was to validate the Indonesian version of this test. Objectives: To learn the validity and reliability of the Indonesian version of Childhood Asthma Control Test (I-CACT). Methods: Translation of the established seven-item questionnaire into the ICACT. Cross-sectional study was conducted among 66 participants aged 4-11 years old which were recruited consecutively. All patient undergone pulmonary function test and measured peak expiratory flow (PEF) regularly. The reliability of I-CACT was assessed using the internal consistency (Cronbach?s ) and the validity was assesed by the Pearson/Spearman correlation test. Results: The mean age was 7.89 years (5.25-11.83y) with predominantly boys. Sixty percent of participants had uncontrollable asthma (score I-CACT ≤19). Both the internal consistency reliability (Cronbach?s  0.762) and the constructed validity (r= 0.384-0.545 ) of the I-CACT were good. No significant correlation was found between the I-CACT score with the FEV1 (r =-0.024; p=0.846) and the variability of PEF (r=-0.218; p=0.079) respectively. Conclusions: I-CACT is a valid and reliable test for assessing asthma control. However, I-CACT does not correlate well with the pulmonary function test and therefore is not a substitute to the role of pulmonary function in assessing asthma control.
Fakultas Kedokteran Universitas Indonesia, 2013
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Siregar, Marsintauli Hasudungan
Abstrak :
[ABSTRAK
Tumor otak (TO) merupakan penyebab kematian kedua dari semua kanker yang terjadi pada anak. TO memiliki gambaran klinis, radiologis dan histopatologis yang sangat bervariasi karena proses pengembangan sel-sel jaringan otak masih berlanjut sampai usia 3 tahun. Data penelitian mengenai TO pada anak masih sedikit. Tujuan: Untuk mengetahui gambaran klinis, radiologis, histopatologis dan faktor prognostik TO di Departemen Ilmu Kesehatan Anak FKUI/ RS. Dr. Ciptomangunkusumo Jakarta periode tahun 2010 - 2015. Metode Penelitian: Kohort retrospektif dilakukan pada semua anak dengan TO primer yang berobat/dirawat di Departemen Ilmu Kesehahatan Anak FKUI/RS Dr. Ciptomangunkusumo Jakarta. Hasil: Didapatkan 88 pasien TO primer, terdiri dari 16 pasien berusia kurang dari 3 tahun dan 72 pasien berusia lebih dari 3 tahun, laki-laki 53% dan perempuan 47%. Anak usia kurang dari 3 tahun mengalami gejala sakit kepala (63%) dan kejang (56%), berdasarkan radiologis letak TO yang terbanyak adalah di cerebral ventrikel (25%) dan cerebellum (24%), berdasarkan histopatologis jenis TO yang terbanyak adalah Astrositoma (31%) dan Medulloblastoma (25%). Anak usia lebih dari 3 tahun mengalami gejala sakit kepala (81%) dan gangguan penglihatan (65%), berdasarkan radiologis letak TO yang terbanyak adalah di cerebellum (24%) dan suprasellar (10 %), berdasarkan histopatologis jenis TO yang terbanyak adalah Medulloblastoma (21%), Astrositoma (18%) dan Glioma (17%). Angka kehidupan TO adalah 37 %. Tidak didapatkan faktor prognostik TO yang bermakna. Kesimpulan: Gejala TO tersering adalah sakit kepala, berdasarkan radiologis letak tumor terbanyak adalah di cerebellum serta berdasarkan histopatologis jenis tumor terbanyak adalah Medulloblastoma dan Astrositoma. Tidak didapatkan faktor prognostik TO pada anak.
ABSTRACT
Primary brain tumors rank second as the most frequent neoplasm in children. The lesions occurring in neonates or infants have been reported to differ from those in older children in terms of their clinical presentation, radiology and histopathology features. Objective To clarify the clinical presentation, radiology, histopathology features. and prognostic factor of primary brain tumors in Child Department Ciptomangunkusumo Hospital Jakarta in 2010 - 2015. Method: Retrospective cohort using medical records and neuroradiological dan histopathological studies, we analyzed each patient?s clinical presentation, tumor location, histopathological diagnosis and treatment then we compared between under 3 years of age and more 3 years of age . The patients were followed until their death or until the end of October 2015. Result: 88 patient of primer brain tumor that consist of 16 patients with under 3 years of age and 72 patients with more 3 years of age. Boys are 53% and girls are 47% . The most symptoms of children under 3 years of age is headache (63%) and seizure (56%), based on radiology the most location tumor is cerebral ventrikel (25%) and cerebellum (24%), based on histopathology the predominant tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms of children more 3 years of age is headache (81%) and visual difficulties (65%), based on radiology the most tumor location is cerebellum (24%) and suprasellar (10 %), based on histopathology the predominat tumor is Medulloblastoma (21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %. There is no prognostic factor of brain tumor. Conclusion: The most symptom of brain tumor is headache, based on radiology the most tumor location is cerebellum, and based on histopathology the predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in children. The lesions occurring in neonates or infants have been reported to differ from those in older children in terms of their clinical presentation, radiology and histopathology features. Objective To clarify the clinical presentation, radiology, histopathology features. and prognostic factor of primary brain tumors in Child Department Ciptomangunkusumo Hospital Jakarta in 2010 - 2015. Method: Retrospective cohort using medical records and neuroradiological dan histopathological studies, we analyzed each patient?s clinical presentation, tumor location, histopathological diagnosis and treatment then we compared between under 3 years of age and more 3 years of age . The patients were followed until their death or until the end of October 2015. Result: 88 patient of primer brain tumor that consist of 16 patients with under 3 years of age and 72 patients with more 3 years of age. Boys are 53% and girls are 47% . The most symptoms of children under 3 years of age is headache (63%) and seizure (56%), based on radiology the most location tumor is cerebral ventrikel (25%) and cerebellum (24%), based on histopathology the predominant tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms of children more 3 years of age is headache (81%) and visual difficulties (65%), based on radiology the most tumor location is cerebellum (24%) and suprasellar (10 %), based on histopathology the predominat tumor is Medulloblastoma (21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %. There is no prognostic factor of brain tumor. Conclusion: The most symptom of brain tumor is headache, based on radiology the most tumor location is cerebellum, and based on histopathology the predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in children. The lesions occurring in neonates or infants have been reported to differ from those in older children in terms of their clinical presentation, radiology and histopathology features. Objective To clarify the clinical presentation, radiology, histopathology features. and prognostic factor of primary brain tumors in Child Department Ciptomangunkusumo Hospital Jakarta in 2010 - 2015. Method: Retrospective cohort using medical records and neuroradiological dan histopathological studies, we analyzed each patient?s clinical presentation, tumor location, histopathological diagnosis and treatment then we compared between under 3 years of age and more 3 years of age . The patients were followed until their death or until the end of October 2015. Result: 88 patient of primer brain tumor that consist of 16 patients with under 3 years of age and 72 patients with more 3 years of age. Boys are 53% and girls are 47% . The most symptoms of children under 3 years of age is headache (63%) and seizure (56%), based on radiology the most location tumor is cerebral ventrikel (25%) and cerebellum (24%), based on histopathology the predominant tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms of children more 3 years of age is headache (81%) and visual difficulties (65%), based on radiology the most tumor location is cerebellum (24%) and suprasellar (10 %), based on histopathology the predominat tumor is Medulloblastoma (21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %. There is no prognostic factor of brain tumor. Conclusion: The most symptom of brain tumor is headache, based on radiology the most tumor location is cerebellum, and based on histopathology the predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in children. The lesions occurring in neonates or infants have been reported to differ from those in older children in terms of their clinical presentation, radiology and histopathology features. Objective To clarify the clinical presentation, radiology, histopathology features. and prognostic factor of primary brain tumors in Child Department Ciptomangunkusumo Hospital Jakarta in 2010 - 2015. Method: Retrospective cohort using medical records and neuroradiological dan histopathological studies, we analyzed each patient?s clinical presentation, tumor location, histopathological diagnosis and treatment then we compared between under 3 years of age and more 3 years of age . The patients were followed until their death or until the end of October 2015. Result: 88 patient of primer brain tumor that consist of 16 patients with under 3 years of age and 72 patients with more 3 years of age. Boys are 53% and girls are 47% . The most symptoms of children under 3 years of age is headache (63%) and seizure (56%), based on radiology the most location tumor is cerebral ventrikel (25%) and cerebellum (24%), based on histopathology the predominant tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms of children more 3 years of age is headache (81%) and visual difficulties (65%), based on radiology the most tumor location is cerebellum (24%) and suprasellar (10 %), based on histopathology the predominat tumor is Medulloblastoma (21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %. There is no prognostic factor of brain tumor. Conclusion: The most symptom of brain tumor is headache, based on radiology the most tumor location is cerebellum, and based on histopathology the predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in children. The lesions occurring in neonates or infants have been reported to differ from those in older children in terms of their clinical presentation, radiology and histopathology features. Objective To clarify the clinical presentation, radiology, histopathology features. and prognostic factor of primary brain tumors in Child Department Ciptomangunkusumo Hospital Jakarta in 2010 - 2015. Method: Retrospective cohort using medical records and neuroradiological dan histopathological studies, we analyzed each patient?s clinical presentation, tumor location, histopathological diagnosis and treatment then we compared between under 3 years of age and more 3 years of age . The patients were followed until their death or until the end of October 2015. Result: 88 patient of primer brain tumor that consist of 16 patients with under 3 years of age and 72 patients with more 3 years of age. Boys are 53% and girls are 47% . The most symptoms of children under 3 years of age is headache (63%) and seizure (56%), based on radiology the most location tumor is cerebral ventrikel (25%) and cerebellum (24%), based on histopathology the predominant tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms of children more 3 years of age is headache (81%) and visual difficulties (65%), based on radiology the most tumor location is cerebellum (24%) and suprasellar (10 %), based on histopathology the predominat tumor is Medulloblastoma (21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %. There is no prognostic factor of brain tumor. Conclusion: The most symptom of brain tumor is headache, based on radiology the most tumor location is cerebellum, and based on histopathology the predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in children. The lesions occurring in neonates or infants have been reported to differ from those in older children in terms of their clinical presentation, radiology and histopathology features. Objective To clarify the clinical presentation, radiology, histopathology features. and prognostic factor of primary brain tumors in Child Department Ciptomangunkusumo Hospital Jakarta in 2010 - 2015. Method: Retrospective cohort using medical records and neuroradiological dan histopathological studies, we analyzed each patient?s clinical presentation, tumor location, histopathological diagnosis and treatment then we compared between under 3 years of age and more 3 years of age . The patients were followed until their death or until the end of October 2015. Result: 88 patient of primer brain tumor that consist of 16 patients with under 3 years of age and 72 patients with more 3 years of age. Boys are 53% and girls are 47% . The most symptoms of children under 3 years of age is headache (63%) and seizure (56%), based on radiology the most location tumor is cerebral ventrikel (25%) and cerebellum (24%), based on histopathology the predominant tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms of children more 3 years of age is headache (81%) and visual difficulties (65%), based on radiology the most tumor location is cerebellum (24%) and suprasellar (10 %), based on histopathology the predominat tumor is Medulloblastoma (21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %. There is no prognostic factor of brain tumor. Conclusion: The most symptom of brain tumor is headache, based on radiology the most tumor location is cerebellum, and based on histopathology the predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in children. The lesions occurring in neonates or infants have been reported to differ from those in older children in terms of their clinical presentation, radiology and histopathology features. Objective To clarify the clinical presentation, radiology, histopathology features. and prognostic factor of primary brain tumors in Child Department Ciptomangunkusumo Hospital Jakarta in 2010 - 2015. Method: Retrospective cohort using medical records and neuroradiological dan histopathological studies, we analyzed each patient?s clinical presentation, tumor location, histopathological diagnosis and treatment then we compared between under 3 years of age and more 3 years of age . The patients were followed until their death or until the end of October 2015. Result: 88 patient of primer brain tumor that consist of 16 patients with under 3 years of age and 72 patients with more 3 years of age. Boys are 53% and girls are 47% . The most symptoms of children under 3 years of age is headache (63%) and seizure (56%), based on radiology the most location tumor is cerebral ventrikel (25%) and cerebellum (24%), based on histopathology the predominant tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms of children more 3 years of age is headache (81%) and visual difficulties (65%), based on radiology the most tumor location is cerebellum (24%) and suprasellar (10 %), based on histopathology the predominat tumor is Medulloblastoma (21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %. There is no prognostic factor of brain tumor. Conclusion: The most symptom of brain tumor is headache, based on radiology the most tumor location is cerebellum, and based on histopathology the predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in children. The lesions occurring in neonates or infants have been reported to differ from those in older children in terms of their clinical presentation, radiology and histopathology features. Objective To clarify the clinical presentation, radiology, histopathology features. and prognostic factor of primary brain tumors in Child Department Ciptomangunkusumo Hospital Jakarta in 2010 - 2015. Method: Retrospective cohort using medical records and neuroradiological dan histopathological studies, we analyzed each patient?s clinical presentation, tumor location, histopathological diagnosis and treatment then we compared between under 3 years of age and more 3 years of age . The patients were followed until their death or until the end of October 2015. Result: 88 patient of primer brain tumor that consist of 16 patients with under 3 years of age and 72 patients with more 3 years of age. Boys are 53% and girls are 47% . The most symptoms of children under 3 years of age is headache (63%) and seizure (56%), based on radiology the most location tumor is cerebral ventrikel (25%) and cerebellum (24%), based on histopathology the predominant tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms of children more 3 years of age is headache (81%) and visual difficulties (65%), based on radiology the most tumor location is cerebellum (24%) and suprasellar (10 %), based on histopathology the predominat tumor is Medulloblastoma (21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %. There is no prognostic factor of brain tumor. Conclusion: The most symptom of brain tumor is headache, based on radiology the most tumor location is cerebellum, and based on histopathology the predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in children. The lesions occurring in neonates or infants have been reported to differ from those in older children in terms of their clinical presentation, radiology and histopathology features. Objective To clarify the clinical presentation, radiology, histopathology features. and prognostic factor of primary brain tumors in Child Department Ciptomangunkusumo Hospital Jakarta in 2010 - 2015. Method: Retrospective cohort using medical records and neuroradiological dan histopathological studies, we analyzed each patient?s clinical presentation, tumor location, histopathological diagnosis and treatment then we compared between under 3 years of age and more 3 years of age . The patients were followed until their death or until the end of October 2015. Result: 88 patient of primer brain tumor that consist of 16 patients with under 3 years of age and 72 patients with more 3 years of age. Boys are 53% and girls are 47% . The most symptoms of children under 3 years of age is headache (63%) and seizure (56%), based on radiology the most location tumor is cerebral ventrikel (25%) and cerebellum (24%), based on histopathology the predominant tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms of children more 3 years of age is headache (81%) and visual difficulties (65%), based on radiology the most tumor location is cerebellum (24%) and suprasellar (10 %), based on histopathology the predominat tumor is Medulloblastoma (21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %. There is no prognostic factor of brain tumor. Conclusion: The most symptom of brain tumor is headache, based on radiology the most tumor location is cerebellum, and based on histopathology the predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in children. The lesions occurring in neonates or infants have been reported to differ from those in older children in terms of their clinical presentation, radiology and histopathology features. Objective To clarify the clinical presentation, radiology, histopathology features. and prognostic factor of primary brain tumors in Child Department Ciptomangunkusumo Hospital Jakarta in 2010 - 2015. Method: Retrospective cohort using medical records and neuroradiological dan histopathological studies, we analyzed each patient?s clinical presentation, tumor location, histopathological diagnosis and treatment then we compared between under 3 years of age and more 3 years of age . The patients were followed until their death or until the end of October 2015. Result: 88 patient of primer brain tumor that consist of 16 patients with under 3 years of age and 72 patients with more 3 years of age. Boys are 53% and girls are 47% . The most symptoms of children under 3 years of age is headache (63%) and seizure (56%), based on radiology the most location tumor is cerebral ventrikel (25%) and cerebellum (24%), based on histopathology the predominant tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms of children more 3 years of age is headache (81%) and visual difficulties (65%), based on radiology the most tumor location is cerebellum (24%) and suprasellar (10 %), based on histopathology the predominat tumor is Medulloblastoma (21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %. There is no prognostic factor of brain tumor. Conclusion: The most symptom of brain tumor is headache, based on radiology the most tumor location is cerebellum, and based on histopathology the predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic factor of brain tumor., Background: Primary brain tumors rank second as the most frequent neoplasm in children. The lesions occurring in neonates or infants have been reported to differ from those in older children in terms of their clinical presentation, radiology and histopathology features. Objective To clarify the clinical presentation, radiology, histopathology features. and prognostic factor of primary brain tumors in Child Department Ciptomangunkusumo Hospital Jakarta in 2010 - 2015. Method: Retrospective cohort using medical records and neuroradiological dan histopathological studies, we analyzed each patient?s clinical presentation, tumor location, histopathological diagnosis and treatment then we compared between under 3 years of age and more 3 years of age . The patients were followed until their death or until the end of October 2015. Result: 88 patient of primer brain tumor that consist of 16 patients with under 3 years of age and 72 patients with more 3 years of age. Boys are 53% and girls are 47% . The most symptoms of children under 3 years of age is headache (63%) and seizure (56%), based on radiology the most location tumor is cerebral ventrikel (25%) and cerebellum (24%), based on histopathology the predominant tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms of children more 3 years of age is headache (81%) and visual difficulties (65%), based on radiology the most tumor location is cerebellum (24%) and suprasellar (10 %), based on histopathology the predominat tumor is Medulloblastoma (21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %. There is no prognostic factor of brain tumor. Conclusion: The most symptom of brain tumor is headache, based on radiology the most tumor location is cerebellum, and based on histopathology the predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic factor of brain tumor.]
2016
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Pricilia Gunawan Halim
Abstrak :
Pendekatan integrasi antara terapi paliatif dan perawatan penyakit kronik dan atau mengancam jiwa telah banyak digunakan dalam beberapa tahun terakhir. Hingga saat ini, masih banyak yang beranggapan bahwa terapi paliatif hanya ditujukan untuk pasien dengan penyakit berat yang sudah berada di stadium terminal atau akhir hidupnya, namun pada kenyataannya banyak pasien mendapatkan manfaat dari terapi paliatif sedini mungkin. Penelitian ini merupakan uji klinis acak terkontrol yang bertujuan untuk mengetahui manfaat integrasi terapi paliatif pada pasien anak dengan penyakit keganasan. Pasien terdiri dari anak  dengan penyakit keganasan usia 2-18 tahun yang dikonsulkan kepada tim paliatif. Pasien dibagi menjadi dua kelompok secara acak, yakni kelompok kontrol (30 anak) dan kelompok intervensi (30 anak). Intervensi berupa kunjungan rumah, komunikasi dua arah antara tenaga terlatih dengan pasien dan orang tua, dibagi menjadi 6 sesi (1 sesi setiap 2 minggu) yang berfokus pada edukasi penyelesaian masalah, manajemen gejala, perawatan diri sendiri, komunikasi, pembuatan keputusan dan pendampingan rencana perawatan lanjutan. Pasien diikuti dan dilakukan penilaian kualitas hidup dengan kuesioner Pediatric Quality of  Life Innitiative (PedsQLTM) modul kanker 3.0, intensitas gejala dinilai dengan Edmonton Symptoms Assesment Score (ESAS), frekuensi kunjungan unit gawat darurat (UGD) pasien anak dengan penyakit keganasan dicatat selama periode penelitian dan dibandingkan dengan sebelum penelitian. Kelompok intervensi memiliki kualitas hidup lebih tinggi bermakna (81,63) dibandingkan kelompok kontrol (62,39), p<0,001. Ranah kualitas hidup yang paling meningkat secara signifikan adalah ranah nyeri, mual, kecemasan prosedur, kecemasan tata laksana, dan khawatir. Intervensi paliatif dapat menurunkan intensitas gangguan tidur (p=0,003) dan anoreksia pada pasien (p<0,001). Intervensi paliatif dapat menurunkan kunjungan UGD sebanyak 4,77 kali pada pasien anak dengan penyakit keganasan (OR 4,77, 95% IK 1,29-17,65; p=0,018). ......In these last few years, an integrated approach between palliative care and chronic and/or life-threatening conditions care have been widely used. Many people think that palliative care is only intended for those with end stage of disease or in the end of life period. In fact, many patients had benefit from early palliative integration. This study is aimed to know the role of palliative intervention in child with malignancy. A randomized controlled trial comparing patients who were given palliative care (a 3-month home visit) and those who were not (intervention vs control group) was conducted, each group containing 30 patients. Patients consisted of children with cancer aged 2-18 years old who were consulted to palliative team. A two-way communication between a trained health worker and patients with or without their parents were conducted as the intervention (report by proxy or self-report). Interventions were given in 6 sessions (1 session every 2 weeks) focusing on problems solving education, symptoms management, self-care, communication, decision making, and long-term care plan assistance. In the first and twelfth week of the intervention, all patients were assessed with the Pediatric Quality of Life Inventory (PedsQLTM) questionnaire cancer module 3.0. Symptomps intensity were assessed by Edmonton Symptoms Assesment Score (ESAS). Emergency room admissions from the last 3 months were noted before patients were enrolled in the study. During the follow up period, ER admissions were recorded further. Data was analyzed using bivariate analysis, OR calculations were performed to see the effect of interventions on outcomes in this study. A significant difference of quality of life was found between the two groups with average total score in control group 62.39 and intervention group 81.63 (p<0.001). Most significant increased domains were pain, nausea, procedural anxiety, treatment anxiety, and worry. Intensity of sleep disturbance (p=0.003) and anorexia (p<0.001) were decreased significantly in intervention group. Emergency room admissions were reduced by 4.7 times in intervention group (OR 4.77, 95% CI 1.29-17.65; p=0.018).
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2019
T58736
UI - Tesis Membership  Universitas Indonesia Library
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Henni Wahyu Triyuniati
Abstrak :
Latar belakang: Keterlambatan perkembangan adalah morbiditas jangka panjang akibat prematur dan perdarahan intraventrikel (PIV). Uji Capute scales merupakan alat perkembangan yang praktis dan dapat menegakkan keterlambatan perkembangan. Tujuan: mengetahui luaran keterlambatan perkembangan dengan uji Capute scales pada anak dengan riwayat prematur dan PIV. Metode: Studi potong lintang dilakukan terhadap 96 anak usia koreksi 6-36 bulan di RSCM. Penelitian ini mencari prevalens dan jenis keterlambatan perkembangan dengan uji Capute scales antara kelompok prematur dengan PIV sedang-berat dan kelompok PIV ringan. Analisis dilakukan untuk mengetahui hubungan antara derajat PIV, usia gestasi, berat lahir, apneu of prematurity (AOP), ventilator mekanik dini, resusitasi aktif, dan patent ductus arteriosus (PDA) terhadap keterlambatan perkembangan. Hasil: Prevalens keterlambatan perkembangan pada kelompok anak dengan prematur dan PIV adalah 19,8%. Kelompok anak dengan riwayat prematur dan PIV sedang berat memiliki 2,56 kali mengalami keterlambatan perkembangan umum dibandingkan dengan kelompok prematur dan PIV ringan (IK95% 1,176-5,557; nilai p=0,037). Jenis keterlambatan perkembangan kognitif/visual-motor didapatkan peningkatan risiko tertinggi (rasio prevalens 4,73 (IK95%1,92-11,69; nilai p=0,001) dibandingkan keterlambatan perkembangan bahasa. Analisis multivariat menunjukkan apneu of prematurity (AOP) adalah faktor risiko independen yang berhubungan dengan luaran keterlambatan perkembangan pada kelompok prematur dan PIV (OR 4,01 (IK95%1,37-11,75); nilai p=0,011). Kesimpulan: Derajat PIV berperan sebagai salah satu komorbid yang mempengaruhi luaran keterlambatan perkembangan.
Background: Neurodevelopmental delay is among one of long-term morbidities for children with history of prematurity and intraventricular hemorrhage (IVH). The Capute scales test is a practical developmental tool with diagnostic value for neurodevelopmental delay. Objective: To investigate neurodevelopmental delay outcome using Capute scales test. Methods: It is a cross-sectional study involving 96 children at 6-36 months corrected age with history of prematurity and IVH in RSCM Jakarta. This study measures prevalence and characteristics of neurodevelopmental delay among children with prematurity and IVH mild-severe IVH group compared with mild IVH group. Analysis was done to determine relationship between IVH grades, gestational age, birth weight, apneu of prematurity (AOP), early mechanical ventilator use, active resuscitation history, and patent ductus arteriosus (PDA) and neurodevelopmental delay. Results: Prevalens of neurodevelopmental delay in children with history of prematurity and IVH is 19,8%. Premature children with mild-severe IVH group showed greatest risk in cognitive/visual-motor delay (PR 4,73 (95%CI 1,92-11,69; p=0,001) than language delay. Multivariate analysis showed AOP is the only independent risk factor related to neurodevelopmental delay in children with history of prematurity and IVH (OR 4,01 (95%CI 1,37-11,75); p=0,011). Conclusion: IVH grades contribute as one of comorbidities which influence neurodevelopmental delay.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2020
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Lucyana
Abstrak :
ABSTRAK
Pendahuluan: Ensefalitis pada anak lebih sering dijumpai daripada dewasa dan luaran buruk terjadi pada 60% subjek yang terkena. Hingga saat ini belum ada data mengenai profil dan luaran pasien ensefalitis anak di Indonesia. Tujuan: Mengetahui profil dan luaran pasien ensefalitis akut pada anak Metode: Penelitian retrospektif ini menggunakan data rekam medis tahun 2014- 2018 di 3 rumah sakit pendidikan (RSCM, RSU Tangerang, RSUP Fatmawati). Gejala klinis awal, pleositosis CSS, abnormalitas neuroimaging, abnormalitas elektrofisiologis (EEG) dicatat dan luaran dinilai saat pasien pulang/meninggal dan dinyatakan sebagai luaran baik atau buruk. Hasil: Terdapat 657 pasien yang memenuhi kriteria ICD X sesuai kriteria inklusi dari 3 rumah sakit, dan data dari 190 subjek dianalisis dalam penelitian ini. Subjek penelitian didominasi oleh anak usia > 1 tahun (83%). Kejang didapatkan pada 87% subjek yang diteliti dan 80%nya merupakan kejang umum. Defisit neurologis fokal terdapat pada 47% subjek (90 pasien). Pemeriksaan penunjang yang menunjukkan abnormalitas tertinggi adalah EEG (90%). Kriteria diagnostik probable terpenuhi pada 62% subjek. Mortalitas didapatkan pada 23% subjek, dengan proporsi terbanyak berasal dari RSU Tangerang. Kejang fokal dan usia > 1 tahun merupakan faktor risiko yang berperan meningkatkan luaran buruk saat pulang 3 kali lipat (p: 0,006 dan p: 0,03). Simpulan: Profil ensefalitis akut pada anak lebih banyak dijumpai pada usia > 1 tahun, dengan gejala yang sering dijumpai saat awal adalah demam, dan kejang. Pemeriksaan penunjang EEG adalah pemeriksaan tertinggi yang menunjukkan hasil positif pada pasien dugaan ensefalitis. Kejang fokal dan usia > 1 tahun merupakan faktor risiko luaran buruk.
ABSTRACT
Introduction: Encephalitis in pediatric population is more frequent than adult. The outcome has been reported to have poor prognosis in 60% of cases. No data of peidatric encephalitis in Indonesia has been reported yet. Objectives: Evaluate pediatric acute encephalitis profile and factors that influence its outcome. Methods: This retrospective research used medical records data from year 2014- 2018 in 3 teaching hospitals (RSCM, RSU Tangerang, RSUP Fatmawati). We documented clinical presentation at admission, pleocytosis CSF, neuroimaging abnormality, electrophysiologic abnormality (EEG), and outcome at discharge which classified as good vs. poor outcome. Results: Among 657 patients identified using ICD X in all 3 hospitals, there were a total of 190 subjects included in this study. Eighty three percent of subjects aged > 1 years. Seizure was present in 87% subjects, and 80% of those subjects experienced generalized seizure. Focal neurological deficits was shown in 47% subjects (90 patients). Among investigation, EEG shown positive results in 90% examined subjects, while CT scan were the most prevalent. We found probable diagnostic criteria in majority of subjects (62%). Mortality was 23%, and RSU Tangerang was the major contributor. Focal seizure and age > 1 year were the risk factors associated with 3 times increased risk of poor outcome (p: 0,006 and p: 0,03). Conclusions: Age > 1 year is more prevalent in pediatric acute encephalitis. Among most common clinical presentation are fever and seizure. Abnormal EEG finding in suspected encephalitis cases give the most positive result. Focal seizure and age > 1 year were the risk factors for poor outcome
2019
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Sita Ariyani
Abstrak :
Latar belakang: Penyakit Kawasaki (PK) merupakan vaskulitis akut sistemik yang belum diketahui penyebabnya dan mempunyai predileksi pada arteri koroner terutama bayi dan anak balita. Sebanyak 20-40% kasus PK yang tidak diobati akan mengalami kelainan arteri koroner. Masalah PK di Indonesia saat ini adalah masih banyak kasus yang underdiagnosis dan terlambat didiagnosis, serta beberapa kasus overdiagnosis. Sejauh ini belum ada publikasi penelitian tentang PK di Indonesia. Tujuan: Mengetahui profil klinis dan pemeriksaan penunjang PK pada anak di Indonesia. Metode: Penelitian deskriptif potong lintang. Data diperoleh dari rekam medis pasien anak 0-18 tahun dengan diagnosis PK selama periode 1 Agustus 2011 hingga 31 Juli 2012 di 3 rumah sakit di Jakarta dan Tangerang. Hasil: Terdapat 66 subjek yang sesuai dengan diagnosis PK. Sebanyak 77% subjek berusia balita dengan usia tersering 1-2 tahun. Proporsi anak lelaki lebih tinggi dibandingkan perempuan dengan perbandingan 2:1. Seluruh subjek mengalami demam dengan gambaran klinis paling sering adalah perubahan pada bibir dan rongga mulut seperti eritema, bibir pecah-pecah, lidah stroberi, dan eritema difus mukosa orofaring (100%), ruam polimorfik (89%), dan injeksi konjungtiva tanpa eksudat (88%). Gambaran klinis paling jarang adalah limfadenopati servikal unilateral (53%). Anemia dan leukositosis sering terjadi pada fase akut, sedangkan trombositosis mulai terjadi pada minggu kedua. Peningkatan LED dan CRP terjadi pada fase akut, namun pada 15% subjek peningkatan LED tidak disertai oleh peningkatan CRP atau sebaliknya. Hipoalbuminemia terjadi pada 70% subjek. Gambaran infiltrat pada foto toraks didapatkan pada 71% subjek. Aneurisma arteri koroner pada ekokardiografi saat awal diagnosis didapatkan pada 30% subjek. Sebagian besar merupakan aneurisma kecil, 3% aneurisma sedang, dan 1% aneurisma raksasa. Simpulan: Gambaran klinis paling sering selain demam adalah perubahan pada bibir dan rongga mulut, ruam polimorfik, dan injeksi konjungtiva tanpa eksudat, sedangkan yang paling jarang adalah limfadenopati servikal unilateral. Pemeriksaan LED dan CRP sebaiknya dilakukan bersamaan untuk mendukung diagnosis. Hipoalbuminemia dan gambaran infiltrat pada foto toraks mungkin dapat dipertimbangkan sebagai alat bantu diagnosis PK pada anak di Indonesia, namun masih membutuhkan penelitian lebih lanjut untuk membuktikannya. ...... Background: Kawasaki disease (KD) is an acute systemic vasculitis with unknown cause. The main predilections are the coronary arteries, especially in infants and children under five. As many as 20-40% of untreated KD will develop coronary problems. Currently, many of the KD cases in Indonesia are still under- or late diagnosed, and some cases are even overdiagnosed. However, there has not been any research publication on KD in Indonesia. Objective: To describe the clinical and supportive examination profiles of KD in Indonesian children. Method: A cross-sectional observational study of children under 18 years old with KD diagnosed within August 1st 2011 and July 31st 2012 was performed. Data were obtained from the medical records of patients from 3 hospitals in Jakarta and Tangerang. Results: Of 66 subjects diagnosed of KD, 77% subjects were children aged 1-2 years old, with male and female ratio was 2:1. All subjects had fever with common clinical profiles were: changes in lips and oral cavity such as erythema, lips cracking, strawberry tongue and diffuse erythema of oropharyngeal mocosae; polymorphic rashes; and non-exudative conjunctival injection (100%, 89%, and 88%, respectively). Unilateral cervical lymphadenopathy was seen in 53% subjects. Anemia and leukocytosis were frequently seen in acute phase, while thrombocytosis developed during the second week. The ESR and CRP also increased during acute phase. However, in 15% subjects with increased ESR, the CRP remained normal, and vice versa. Hypoalbuminemia occured in 70% subjects, and infiltrate on chest xray appeared in 71% subjects. The incidence of coronary artery aneurysm at initial echocardiography was 30%, with small aneurysm were predominant, 3% considered moderate, and 1% was categorized as giant aneurysm. Conclusion: Changes in lips and oral cavity, polymorphic rashes, and non-exudative conjunctival injection are the most common clinical profiles, besides fever. Unilateral cervical lympadenopathy is the least frequent manifestation. The ESR and CRP examinations should be done to support the diagnosis of KD. Hypoalbuminemia and infiltrate findings on chest xrays might be considered as an aid in diagnosing KD in Indonesian children. However, further study is needed for validation.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2013
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Primo Parmato
Abstrak :
Latar belakang: Palsi serebral (PS) adalah salah satu gangguan fisis penyebab utama gangguan pertumbuhan dan perkembangan anak. Permasalahan PS yang menjadi perhatian bagi orangtua adalah keterlambatan perkembangan motorik terutama kemampuan berjalan. Sampai saat ini belum didapatkan data prevalens dan faktor prediktor pada masa anak apa saja yang berhubungan dengan kemampuan berkalan pasien PS. Tujuan: Untuk mengetahui prevalens kemampuan berjalan pasien PS, dan mengetahui faktor prediktor apa saja yang berhubungan dan yang paling berperan terhadap kemampuan berjalan pasien PS pada masa anak. Metode: 102 pasien PS yang berusia 6 tahun ke atas dilakukan pengambilan data melalui wawancara orang tua dan rekam medis mengenai kemampuan berjalan pasien PS dan faktor prediktor pada masa anak yang berhubungan dengan kemampuan berjalan pasien PS. Pengambilan data dilakukan di Rumah Sakit Cipto Mangunkusumo (RSCM) dan Yayasan Pembinaan Anak Cacat (YPAC). Hasil: Sebanyak 27 pasien (26.5%) berjalan tanpa alat bantu, 13 pasien (12.7%) berjalan dengan alat bantu, dan 62 pasien (60.8%) tidak dapat berjalan walau dengan alat bantu. Faktor prediktor yang berhubungan dengan kemampuan berjalan pasien PS adalah kemampuan menahan posisi duduk tanpa topangan sebelum usia 2 tahun (P<0.001; OR=6.89; IK 95%=2.42-19.71) dan tipe PS spastik unilateral (OR=7.36; IK 95%=1.86-29.18). Simpulan: Prevalens pasien PS yang dapat berjalan tanpa alat bantu adalah 26.5%, berjalan dengan alat bantu adalah 12.7%, dan tidak dapat berjalan walau dengan alat bantu 60.8%. Faktor prediktor yang berhubungan dengan kemampuan berjalan pasien PS adalah kemampuan menahan posisi duduk tanpa topangan sebelum usia 2 tahun dan spastik unilateral. Faktor prediktor yang paling berperan adalah kemampuan menahan posisi duduk tanpa topangan sebelum usia 2 tahun.
Background: Cerebral palsy (CP) is one of the main disorder of growth and development in child. The problem of CP often asked by parents is delayed of motoric development particularly about walking ability. There has been no data about prevalence and childhood predicting factor which has relationship with walking ability in CP patient. Objectives: To determine the prevalence of walking ability in CP patient, to identify childhood predicting factor relating to walking ability in CP patient, and also to determine the most childhood predicting factor of walking ability in CP patient. Methods: Data has been taken from 102 CP patients which has age above 6 years old, by interviewed to the parents or by medical record. The places of research are Cipto Mangunkusumo Hospital and Yayasan Pembinaan Anak Cacat (YPAC). Results: 27 patients (26.5%) could walk without assistive device, 13 patients (12.7%) could walk with assistive device, and 62 patients (60.8%) could not walk even with assistive device. The childhood predicting factor of waking ability in CP patients is the ability to maintain sitting position before age 2 years old (P<0.001; OR=6.89; CI 95%=2.42-19.71) and the spastic unilateral CP type (OR = 7.36; CI 95% = 1.86-29.18). Conclusions: The prevalence of walking ability in CP patient is 26.6% walk without assistive device, 12.7% walk with assistive device, and 60.8% could not walk even with assistive device. The predicting factor relating to walking ability in CP patients is the ability to maintain sitting position before age 2 years old and the spastic unilateral CP type. The most predicting factor of walking ability in CP patients is the ability to maintain sitting position before age 2 years old.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2013
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Lies Dewi Nurmalia
Abstrak :
ABSTRAK Latar Belakang. Biomarker dapat digunakan untuk memprediksi derajat keparahan trauma kepala. Tujuan. Mengetahui hubungan antara kadar S100B dengan derajat keparahan trauma kepala dan kelainan CT scan kepala. Metode Penelitian. Penelitian potong lintang di IGD RSUPN Cipto Mangunkusumo, RSUP Fatmawati, dan RS Permata Cibubur selama Juli-Desember 2015. Subjek adalah anak usia 1-18 tahun yang mengalami trauma kepala dengan onset <24 jam. Setiap subjek dilakukan pemeriksaan skor Skala Koma Glasgow Pediatrik, pemeriksaan CT scan kepala bila terdapat indikasi, serta pemeriksaan kadar S100B dari serum. Hasil Penelitian. Subjek penelitian terdiri atas 20 subjek trauma kepala ringan dan 18 subjek trauma kepala sedang. Hasil penelitian menunjukkan terdapat perbedaan bermakna kadar S100B kelompok trauma trauma kepala sedang dan kepala ringan; median (rentang) 0,173 (0,054-0,812) μg/L dibandingkan 0,067 (0,039-0,084) μg/L, p<0,001. Selain itu juga terdapat perbedaan bermakna antara kelompok yang terdapat kelainan CT scan kepala dibandingkan dengan yang tidak ada kelainan; 0,124 (0,051-0,812) μg/L dan 0,067 (0,039-0,084) μg/L, p=0,001. Berdasarkan analisis ROC, kadar S100B serum sangat kuat untuk memprediksi trauma kepala sedang (AUC 0,818, p=0,001 dan IK95% 0,668-0,969) dengan nilai cut-off 0,083 μg/L. Simpulan. Kadar S100B serum pada trauma kepala sedang secara bermakna lebih tinggi dari trauma kepala ringan serta memiliki kemampuan diskriminasi sangat baik untuk memprediksi derajat keparahannya.
ABSTRACT Background. Biomarker has ability to predict the severity of TBI and abnormal CT scan. Objectives. To determine the association between S100B level with the severity of pediatric TBI and intracranial injury. Methods. A cross-sectional study at Emergency Department of RSUPN Cipto Mangunkusumo, RSUP Fatmawati, and Permata Cibubur Hospital on July- December 2015. Subjects were 1-18 year-old children with TBI, onset within 24 hours before admission. We measured Pediatric GCS score, serum S100B level, and performed cranial CT scan if indicated. Results. Twenty subjects had mild TBI and 18 subjects had moderate TBI were included. S100B levels were higher in children with moderate TBI as compared to children with mild TBI; 0,173 (0,054-0,812) μg/L vs 0,067 (0,039-0,084) μg/L, p<0,001. S100B levels were significantly elevated in children following TBI with abnormal cranial CT scan as compared to children with a normal CT scan (0,124 (0,051-0,812) μg/L vs 0,067 (0,039-0,084) μg/L, p=0,001). AUC for S100B was also significant (0,818, p=0,001, CI95% 0,668-0,969) as prediction of moderate TBI with cut-off point 0,083 μg/L. Conclusions. Children with moderate TBI had significantly higher S100B levels as compared to children with mild TBI. Cut-off point S100B level at 0,083 μg/L has good ability to predict the severity of TBI.
Depok: Fakultas Kedokteran Universitas Indonesia, 2016
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Lies Dewi Nurmalia
Abstrak :
ABSTRAK
Latar Belakang Biomarker dapat digunakan untuk memprediksi derajat keparahan trauma kepala Tujuan Mengetahui hubungan antara kadar S100B dengan derajat keparahan trauma kepala dan kelainan CT scan kepala Metode Penelitian Penelitian potong lintang di IGD RSUPN Cipto Mangunkusumo RSUP Fatmawati dan RS Permata Cibubur selama Juli Desember 2015 Subjek adalah anak usia 1 18 tahun yang mengalami trauma kepala dengan onset
ABSTRACT
Background Biomarker has ability to predict the severity of TBI and abnormal CT scan Objectives To determine the association between S100B level with the severity of pediatric TBI and intracranial injury Methods A cross sectional study at Emergency Department of RSUPN Cipto Mangunkusumo RSUP Fatmawati and Permata Cibubur Hospital on July December 2015 Subjects were 1 18 year old children with TBI onset within 24 hours before admission We measured SKG score serum S100B level and performed cranial CT scan if indicated Results Twenty subjects had mild TBI and 18 subjects had moderate TBI were included S100B levels were higher in children with moderate TBI as compared to children with mild TBI 0 173 0 054 0 812 g L vs 0 067 0 039 0 084 g L p;Background Biomarker has ability to predict the severity of TBI and abnormal CT scan Objectives To determine the association between S100B level with the severity of pediatric TBI and intracranial injury Methods A cross sectional study at Emergency Department of RSUPN Cipto Mangunkusumo RSUP Fatmawati and Permata Cibubur Hospital on July December 2015 Subjects were 1 18 year old children with TBI onset within 24 hours before admission We measured SKG score serum S100B level and performed cranial CT scan if indicated Results Twenty subjects had mild TBI and 18 subjects had moderate TBI were included S100B levels were higher in children with moderate TBI as compared to children with mild TBI 0 173 0 054 0 812 g L vs 0 067 0 039 0 084 g L p;Background Biomarker has ability to predict the severity of TBI and abnormal CT scan Objectives To determine the association between S100B level with the severity of pediatric TBI and intracranial injury Methods A cross sectional study at Emergency Department of RSUPN Cipto Mangunkusumo RSUP Fatmawati and Permata Cibubur Hospital on July December 2015 Subjects were 1 18 year old children with TBI onset within 24 hours before admission We measured SKG score serum S100B level and performed cranial CT scan if indicated Results Twenty subjects had mild TBI and 18 subjects had moderate TBI were included S100B levels were higher in children with moderate TBI as compared to children with mild TBI 0 173 0 054 0 812 g L vs 0 067 0 039 0 084 g L p;Background Biomarker has ability to predict the severity of TBI and abnormal CT scan Objectives To determine the association between S100B level with the severity of pediatric TBI and intracranial injury Methods A cross sectional study at Emergency Department of RSUPN Cipto Mangunkusumo RSUP Fatmawati and Permata Cibubur Hospital on July December 2015 Subjects were 1 18 year old children with TBI onset within 24 hours before admission We measured SKG score serum S100B level and performed cranial CT scan if indicated Results Twenty subjects had mild TBI and 18 subjects had moderate TBI were included S100B levels were higher in children with moderate TBI as compared to children with mild TBI 0 173 0 054 0 812 g L vs 0 067 0 039 0 084 g L p
Fakultas Kedokteran Universitas Indonesia, 2016
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Sarah Rafika Nursyirwan
Abstrak :
ABSTRAK
Latar belakang: Identifikasi faktor-faktor risiko sangat penting dalam memprediksi kasus yang mungkin berkembang menjadi sindrom syok dengue SSD dan expanded dengue syndrome EDS . Alasan penelitian ini dilakukan adalah karena masih terdapat perbedaan dari beberapa hasil penelitian sebelumnya mengenai faktor risiko status nutrisi terhadap terjadinya SSD, angka kematian SSD yang masih cukup tinggi 7,81 , dan menggunakan klasifikasi infeksi virus dengue terbaru menurut pedoman WHO terbaru tahun 2011 dengan kelompok EDS.Tujuan: Mengetahui hubungan faktor risiko status nutrisi dan faktor risiko lain terhadap terjadinya SSD dan hubungan status nutrisi terhadap terjadinya EDS. Metode: Studi retrospektif menggunakan data rekam medik pasien anak usia 0 sampai 200 IU . Kata kunci: anak, status nutrisi, demam berdarah dengue, risiko, syok, expanded dengue syndrome. ABSTRACT
Background Identifying risk factors is critical in predicting possible cases of dengue shock syndrome DSS and expanded dengue syndrome EDS . The reasons for this research are because there are still some differences from previous research on the risk factors of nutritional status on the occurrence of DSS, high mortality rate of DSS 7.81 , and using the latest dengue virus classification according to the latest WHO guidelines 2011 with the EDS group.Aim To know the correlation between risk factors of nutritional status and other risk factors on the occurrence of DSS and the relationship of nutritional status to the occurrence of EDS. Methods This retrospective study used medical record data of children ages 0 to 200 IU . Key words children, nutritional status, dengue hemorrhagic fever, risk, shock, expanded dengue syndrome.
Depok: Fakultas Kedokteran Universitas Indonesia, 2017
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