Hasil Pencarian  ::  Simpan CSV :: Kembali

"Penyakit Asma merupakan penyakit inflamasi (peradangan) kronik saluran napas yang ditandai adanya mengi episodik, batuk dan rasa sesak di dada akibat penyumbatan saluran napas, termasuk dalam kelompok penyakit saluran pernapasan kronik. Asma disebabkan oleh peradangan jalan napas di paru-paru, yang mengakibatkan hipersensitivitas sehingga mudah terjadi iritasi. Pada saat terjadi, saluran udara menyempit dan mengakibatkan berkurangnya udara yang masuk dan keluar paru-paru. Menurut Departemen Kesehatan di Indonesia pravelensi asma merupakan 10 besar penyebab kesakitan dan kematian, diperkirakan 2-5% dari seluruh penduduk Indonesia, artinya ada 12,5 juta pasien asma di indonesia. Lingkungan indoor atau lingkungan dalam ruangan atau rumah mampu memberikan kontribusi faktor pencetus serangan asma lebih besar dibandingkan lingkungan outdoor atau luar ruangan. Faktor lingkungan dalam rumah yang dapat mempengaruhi serangan asma bisa berupa kondisi lingkungan fisik rumah dan perilaku dari keluarga penderita asma. Tujuan penelitian ini adalah untuk mengetahui kondisi kesehatan lingkungan fisik rumah dengan kasus asma akut di wilayah Kota Administrasi Jakarta Timur dengan studi kasus di Rumah Sakit Umum Pusat Persahabatan.Metode penelitian ini menggunakan desain studi kasus kontrol dengan perbandingan 1 : 1 dimana besar sampel yaitu 44 penderita asma akut sebagai kasus dan 44 untuk kontrol. Hasil penelitian didapatkan kondisi kesehatan lingkungan fisik rumah : jenis lantai (p = 1,000; OR = 0,899), jenis dinding (p = 0,800, OR = 0,771), jenis atap (p = 1,000, OR = 1,000), ventilasi (p = 0,830, OR = 1,204), kepadatan penghuni (p = 0,829, OR = 1,207), suhu (p = 1,000, OR = 1,000) dan kelembaban (p = 0,644, OR = 1,379), sumber polutan dalam rumah : jenis bahan bakar yang digunakan (p = 1,000, OR = 2,023) dan penggunaan obat nyamuk bakar (p = 1,000, OR = 0,651) serta zat iritan (Asap rokok) (p = 0,663, OR = 1,330). Karakteristik individu, terkait umur (p = 0,352, OR = 2,222) tidak memiliki hubungan dengan kasus asma akut. Sedangkan jenis kelamin p = 0,002, OR = 0,203 dan riwayat genetik p = 0,000, OR = 47,095. memiliki hubungan dengan kasus asma akut di wilayah Kota Administrasi Jakarta Timur tahun 2012.Berdasarkan hasil penelitian menunjukkan variabel yang berhubungan dengan kasus asma akut di wilayah Kota Administrasi Jakarta Timur tahun 2012 adalah jenis kelamin dan riwayat genetik. Dapat disarankan agar Upaya kesehatan promotif dan preventif terutama ditujukan untuk peningkatan upaya pembinaan dan penyuluhan tentang penyehatan pemukiman rumah sehat/sanitasi rumah dan peningkatan pengetahuan serta informasi kepada masyarakat terutama untuk pengendalian penyakit asma akut.

---

Asthma is an inflammatory disease (inflammation) chronic airways characterized by episodic wheezing, coughing and tightness in the chest due to airway obstruction, belongs to a group of chronic respiratory disease. Asthma is caused by inflammation of the airways in the lungs, resulting in hypersensitivity occur so easily irritated. At the event, narrowed airways and lead to less air in and out of the lungs. According to the Ministry of Health in Indonesia pravelensi asthma is a major cause of illness and 10 deaths, an estimated 2-5% of the entire population of Indonesia, means that there are 12.5 million people with asthma in Indonesia. Indoor environment or in a room or home environment can contribute to trigger asthma attacks greater than outdoor or outdoor environments. Environmental factors in the home that may affect asthma attack can be a condition of the physical environment and the behavior of families with asthma. The purpose of this study was to determine the condition of the physical environment with acute asthma cases in the area of East Jakarta Administration City with a case study on Persahabatan Hospital.

This research method using a case-control study design with a ratio of 1: 1 where a large sample of 44 patients with acute asthma as cases and 44 for controls. Results, the physical home environment health conditions: type of flooring (p = 1.000; OR = 0.899), type of wall (p = 0.800, OR = 0.771), type of roof (p = 1.000, OR = 1.000), ventilation (p = 0.830 , OR = 1.204), occupant density (p = 0.829, OR = 1.207), temperature (p = 1.000, OR = 1.000) and humidity (p = 0.644, OR = 1.379), sources of pollutants in the home: the type of fuel used (p = 1.000, OR = 2.023) and the use of mosquito coils (p = 1.000, OR = 0.651) and an irritant (cigarette smoke) (p = 0.663, OR = 1.330). Individual characteristics, related to age (p = 0.352, OR = 2.222) had no connection with the case of an acute asthma. While gender p = 0.002, OR = 0.203 and p = 0.000 genetic history, OR = 47.095 has a relationship with acute asthma cases in East Jakarta Administration City area in 2012.

Based on the results of the study showed that the variables associated with cases of acute asthma in East Jakarta Administration City area in 2012 were gender and genetic history. Can be suggested that health promotion and prevention efforts primarily aimed at improving the coaching and counseling efforts on restructuring settlement healthy home / home sanitation and improvement of knowledge and information to the public, especially for the control of acute asthma."

"Perokok harus berhenti merokok agar dapat terhindar dari dampak negatif rokok. Berhenti merokok adalah suatu proses yang telah dilakukan beberapa kali sebelum akhirnya perokok tersebut berhasil. Penelitian kualitatif dengan desain Rapid Assesment Procedures ini bertujuan untuk memperoleh informasi mendalam tentang upaya berhenti merokok pada mahasiswa UIN Syarif Hidayatullah Jakarta Tahun 2014. Informan terdiri dari mahasiswa yang sudah pernah berupaya berhenti merokok serta informan kunci yaitu ahli berhenti merokok dan psikolog. Hasil penelitian menunjukkan upaya berhenti merokok mahasiswa diawali dengan beragam motivasi, dilanjutkan dengan berbagai macam proses, yang paling sering adalah mengurangi jumlah rokok yang dikonsumsi dan mengganti kebiasaan merokok dengan hal lain (minum jus, permen, camilan). Hal-hal yang berperan dalam upaya berhenti merokok mahasiswa dalam penelitian ini adalah persepsi terhadap bahaya akibat merokok, informasi bahaya rokok dan peringatan bahaya rokok pada kemasan rokok tapi tidak terlalu besar, dukungan orang-orang terdekat dan niat. Diperlukan kebijakan dan program yang bisa membantu mahasiswa perokok untuk berhenti merokok.

---

Smokers should quit smoking in order to avoid the negative effects of smoking. Quitting smoking is a process that has been done several times before finally smoker is successful. Qualitative research with Rapid Assessment Procedures design aims to obtain in-depth information about quitting smoking in students UIN Syarif Hidayatullah Jakarta in 2014. Informants consisted of students who had never attempted to quit smoking as well as key informants namely smoking cessation experts and psychologists. The results showed smoking cessation student begins with diverse motivations, followed by various processes, which most often is to reduce the number of cigarettes consumed and replace smoking with other things (drinking juice, candy, snack). The things that play a role in smoking cessation efforts of students in this research is the perception of the dangers of smoking, the dangers of smoking information and warning of the dangers of smoking on cigarette packaging but not too large, the support of those closest and intentions. Necessary policies and programs that can help the student smokers to quit smoking."

"Latar Belakang : Infeksi TB laten didefinisikan sebagai kondisi individu yang terinfeksi Mycobacterium Tuberculosis M.tb tetapi saat ini individu tersebut tidak sakit, tidak ada gejala dan gambaran foto toraks normal. Tujuan : Mengetahui proporsi TB laten pada petugas kesehatan di RSUDZA Banda Aceh, Mengetahui karakteristik subjek dan hubungan antara usia, masa kerja, lokasi kerja dan status gizi dengan kejadian TB laten pada petugas kesehatan di RSUDZA Banda Aceh. Metode : Penelitian ini adalah penelitian potong lintang dan mengidentifikasi TB laten menggunkan pemeriksaan uji tuberkulin TST pada petugas kesehatan di RSUDZA serta faktor-faktor yang mempengaruhinya. Pada penelitian ini pengambilan sampel dilakukan pada bulan November 2015. Sampel terdiri dari petugas kesehatan di unit infeksi RS Zainoel Abidin yaitu : Poli DOTS, Poli Paru, Ruang Rawat Infeksi Paru PTT , Respiratory High Care Unit RHCU , Unit Bronkoskopi, Laboratorium Mikrobiologi dan Radiologi. Pengambilan sampel dilakukan dengan menggunakan tehnik consecutive sampling. Hasil : Enam puluh lima petugas kesehatan di RSUDZA Banda Aceh dilakukan uji TST. 35 53,8 TST positif dan 30 46,2 TST negatif. Proporsi TB laten pada petugas kesehatan di RSUDZA Banda Aceh adalah 53,8. Tidak terdapat hubungan bermakna antara usia dengan kejadian TB laten p=0.727. Terdapat hubungan bermakna antara masa kerja dengan kejadian TB laten p=0,0001. Tidak terdapat hubungan bermakna antara lokasi kerja dengan kejadian TB laten p=0,324 dan tidak didapatkan hubungan bermakna antara status gizi dengan kejadian TB laten p=0,522. Kesimpulan : Kejadian TB laten pada petugas kesehatan yang bekerja di tempat risiko tinggi TB di RSUDZA tidak dipengaruhi oleh usia, lokasi kerja, status gizi namun dipengaruhi masa kerja. Proporsi TB laten pada petugas kesehatan di RSUDZA Banda Aceh adalah 53,8.

---

Background : Latent TB infection is defined as the condition of individuals who are infected with Mycobacterium tuberculosis M.tb but this time the individual is no sick, no symptoms and have normal chest X ray.

Objective : To determine the proportion of latent TB among healthcare workers in RSUDZA Banda Aceh, knowing the characteristics of the subjects and the relationship between age, length of employment, work location and the nutritional status and the incidence of latent TB among healthcare workers at RSUDZA.

Methods : This research is an analytic observational study using cross sectional design. Sampling was conducted at RSUDZA during November 2015. The sample consisted of healthcare workers at Directly Observed Short Course Therapy Clinic, Pulmonary Clinic, Integrated Tuberculosis Care PTT, Respiratory High Care Unit RHCU, Bronchoscopy Unit, Microbiology Laboratory and Radiology at RSUDZA.

Results : The proportion of latent TB among healthcare workers in RSUDZA Banda Aceh was 53.8. There was no significant relationship between age and incidence of latent TB infection p 0.727. There is a significant relationship between length of employment incidence of latent TB infection p 0.0001. There was no significant relationship between work location and incidence of latent TB infection p 0.324 and there is no significant relationship between nutritional status and incidence of latent TB infection p 0.522.

Conclusion : The incidence of latent TB infection in health care workers who work in a high risk of TB at RSUDZA is not affected by age, location of work, nutritional status but affected with length of employment. The Proportion of latent TB among healthcare workers in RSUDZA Banda Aceh was 53.8. "

"ABSTRAKLatar Belakang : Penelitian di Toronto kanada menyebutkan hubungan antara gas buang kendaraan dengan penyakit respirasi seperti asma, bronkitis, PPOK, pneumonia dan saluran pernafasan atas. Pada Penelitian ini melihat gangguan obstruksi paru serta faktor-faktor lainnya akibat pajanan gas buang kendaraan.Metode : Desain Penelitian adalah Cross Sectional menggunakan data primer melibatkan 66 orang.Penilaian Obstruksi paru menggunakan spirometri serta pengukuran gas buang kendaraan mengambil pajanaan zat kimia SO2, NO2,dan CO. Analisis Univariat data disajikan dalam bentuk distribusi frekuensi. Analisis Bivariat dipakai uji Chi Square dengan p0,05. Kesimpulan : Gangguan obstruksi paru sebesar 22,7 . Faktor yang bermakna adalah faktor usia dan kebiasaan merokok.

---

ABSTRACTBackground Research in Toronto Canada mentions the relationship between vehicle exhaust with respiratory diseases such as asthma, bronchitis, COPD, pneumonia and upper respiratory tract. In this study looked at pulmonary obstruction disorders as well as other factors due to vehicle exhaust exposure.Method This study design was Cross Sectional using primary data involving 66 people. Assessment Pulmonary obstruction using spirometry as well as measurement of vehicle exhaust gas took exposure to SO2, NO2, and CO chemicals. Univariate analysis of data is presented in the form of frequency distribution. Bivariate analysis used Chi Square test with p 0,05.Conclusions Pulmonary obstruction disorder was 22.7 . A significant factor is age and smoking"

"Merokok dianggap sebagai sumber utama pajanan terhadap karbon monoksida (CO). Pemeriksaan kadar CO udara ekspirasi dapat digunakan sebagai biomarker status merokok. Metode ini mudah dilakukan, non invasif dan menimbulkan kepatuhan yang lebih baik bagi pasien. Penelitian ini bertujuan untuk mengetahui kadar CO udara ekspirasi pada perokok dan bukan perokok sekaligus mengetahui kadar CO pada masing-masing jenis perokok terutama perokok kretek sebagai perokok mayoritas di Indonesia.METODEPenelitian potong lintang yang dilaksanakan pada Januari 2013 sampai Oktober 2013. Jumlah sampel sebanyak 125 orang yang terdiri dari 85 orang kelompok perokok dan 40 orang kelompok bukan perokok dipilih secara consecutive sampling. Dilakukan wawancara untuk mengisi kuesioner data dasar, kuesioner Fagerstorm dan skor Horn yang dilanjutkan dengan anamnesis, pemeriksaan fisis dan pengukuran kadar CO udara ekspirasi dengan menggunakan alat pengukur CO portabel (piCO+cSmokerlyzer Bedfont).HASILPenelitian ini mendapatkan kadar CO udara ekspirasi pada kelompok perokok lebih tinggi dibandingkan kelompok bukan perokok dengan rerata kadar CO pada kelompok perokok sebesar 22 (4;48) ppm dan kelompok bukan perokok sebesar 5,83 + 1,82 ppm (p=0,000). Tidak didapatkan perbedaan kadar CO antara kelompok perokok kretek, perokok putih dan perokok campuran (22 + 10,96 ; 22,60 + 10,44 ; 21,43 + 11,72 ; p=0,943). Faktor yang paling berkorelasi terhadap kadar CO udara ekspirasi pada perokok adalah jenis kelamin, laki-laki cenderung memiliki kadar CO yang lebih tinggi dibandingkan dengan perempuan.KESIMPULANKadar CO udara ekspirasi pada perokok lebih tinggi dibandingkan bukan perokok serta tidak ditemukan perbedaan kadar CO diantara perokok kretek, perokok putih dan perokok campuran. Faktor yang paling berkorelasi terhadap kadar CO udara expirasi pada kelompok perokok adalah jenis kelamin.Kata kunci : Kadar CO udara ekspirasi, perokok, perokok kretek

---

Smoking has been considered as a prime cause of carbon monoxide (CO) exposures.Exhaled air CO measurement is a reliable indicator for smoking status. It is noninvasive, easy procedure and better compliance. The present study was undertaken to measure exhaled air CO levels in smokers and non smokers and also to measure exhaled air CO levels in clove cigarette (kretek) smokers as a majority smokers in Indonesia.

METHOD

This study used cross sectional method conducted from Januari 2013 until October 2013. A Total of 125 subject consist of 85 smokers and 40 non smokers selected based on consecutive sampling. Interview was done to fill out question about sociodemografic and smoking habit, Fagerstorm test for nicotine dependence and Horn score for smokers profile if the respondent is smoker follow by anamnesis, physical examination and breath CO measurement using portable CO analyzer ((piCO+cSmokerlyzer Bedfont).

RESULT

Average exhaled air CO levels were 22 (4;48) ppm in smokers, significantly higher compared to non smokers with the level of exhaled air CO were 5,83 + 1,82 ppm (p=0,000). No significant difference was found (p = 0,943) in the distribution of CO readings of the clove cigarette smokers compared to white cigarette and mix cigarette smokers (22 + 10,96 vs 22,60 + 10,44 vs 21,43 + 11,72) ppm. Gender was the most correlated factor to exhaled air CO levels, men tend to have higher exhaled air CO levels compared to women.

CONCLUSION

Exhaled air CO levels in smokers is higher than non smokers whereas no significant difference in the distribution of breath CO readings between clove cigarette, white cigarette en mix cigarette smokers. The most correlated factor that influence CO levels is gender."

"Latar belakang: Menurut SUSENAS tahun 2017, pengguna rokok elektronik di Indonesia terus meningkat hingga mencapai 4 juta pengguna. Peningkatan ini berdasarkan persepsi masyarakat yang menganggap bahwa rokok elektronik bersifat lebih aman dibandingkan rokok konvensional sehingga dapat digunakan sebagai alat berhenti merokok. Padahal, keefektivitas rokok elektronik masih belum terbukti secara komprehensif. Ditambah lagi, studi mengenai pengetahuan pengguna rokok elektronik di Indonesia masih terbatas. Kesenjangan persepsi ini yang menjadi dasar peneliti ingin penelitian terhadap persepsi pengguna vape tentang rokok elektronik sebagai alat berhenti merokok. Metode: Studi ini menggunakan desain quasi eksperimental yang dilakukan dengan pengerjaan pretest dan posttest setelah pemberian video edukasi. Teknik pengambilan jumlah sampel menggunakan non-probability consecutive (n = 75). Data sampel menggunakan Google Form yang disebarkan kepada responden. Distribusi data diuji menggunakan uji Kolmogorov-Smirnov dan dianalisis bivariat Uji Wilcoxon karena distribusi tidak normal. Hasil: Dari 75 responden, peneliti mendapatkan rata-rata perbedaan persepsi sebesar 2 poin. Hasil uji normalitas data menunjukkan distribusi data tidak normal dan hasil uji Wilcoxon menunjukkan nilai p = 0.000 (p<0,05). Kesimpulan: Terdapat perbedaan bermakna pada persepsi pengguna vape tentang rokok elektronik sebagai alat berhenti merokok melalui skor sebelum dan sesudah pemberian video edukasi. Penelitian in membutuhkan penelitian lanjutan yang dapat menganalisis perilaku terhadap persepsi yang didapat.

---

Introduction: According SUSENAS in 2017, electronic cigerrates users continue to increase up to 4 million users. This is due to society perception that e-cigerattes are more safe than conventional cigarettes so that they can be used as a smoking cessation tool. In fact, the effectiveness of e-cigerattes is still not comprehensively proven. In addition, studies on the knowledge of e-cigarette users in Indonesia are still limited. This perception gap is the basis for researchers wanting to study about vaporize user’s perceptions of e- cigerattes as a smoking cessation tool. Method: This study used a quasi-experimental design which was carried out by doing pretest and posttest after giving an educationl video. The sampling technique used was non-probability consecutive (n = 75). Sample data using Google Form shared to respondents. Data distribution was tested using Kolmogorov-Smirnov test and analyzed bivariately using Wilcoxon test due to abnormal distribution. Result: From 75 respondents, researchers got an average difference of 2 points in perception. The results of the data normality test showed that the data distribution was ab normal, and the Wilcoxon test results showed the value of p = 0.000 (p <0.05). Conclusion: There is a significant difference in the perception of vape users about electronic cigarettes as a smoking cessation tool through scores before and after the provision of educational videos. This research requires further research that can analyze the behavior of the perceptions obtained."

"[ABSTRAKLatar belakang: Kasus baru dan kematian kanker paru semakin meningkat. Rokok tembakau sangat berperan tetapi hanya 15% yang menderita kanker paru. Oleh karena itu faktor genetik diduga berperan pada kanker paru. Penelitian-penelitian kohort selama ini menunjukan hubungan bermakna risiko kanker paru dengan riwayat kanker di keluarga. Tujuan: Tujuan utama dari penelitian ini adalah untuk menentukan proporsi subjek kanker paru dengan riwayat kanker pada keluarga.Metode: Penelitian ini adalah studi observasi deskriptif potong lintang dengan subjek kanker paru yang berobat jalan maupun inap di RSUP Persahabatan Jakarta 1 Januari 2013 sampai 31 Mei 2015.Hasil: Subjek penelitian 380 dengan komposisi laki-laki lebih banyak dibandingkan perempuan (72,9% banding 27,1%) dengan median 56 tahun dan nilai minimum dan maksimum 20-86 (66) tahun. Sebanyak 65.3% subjek adalah perokok. Dari total subjek yang merokok, 33,2% termasuk perokok dengan Indeks Brickman (IB) sedang. Jenis sel kanker terbanyak adalah masuk kelompok Kanker Paru Karsinoma Bukan Sel Kecil (KPKBSK) yaitu adenokarsinoma 73,4%. Sebagian besar subjek terdiagnosis pada stage lanjut baik pada kelompok KPKBSK maupun Kanker Paru Karsinoma Sel Kecil (KPKSK). Proporsi subjek dengan riwayat kanker keluarga sebesar 8,2% dengan subjek laki-laki lebih besar dibandingkan perempuan (5,8% dibandingkan 2,4%). Nilai minimum-maksimum usia 35-72 tahun, median 55 tahun. Subjek yang merokok hanya ditemukan pada laki-laki sebanyak 71% dan jenis kanker terbanyak adenokarsinoma 71%. Hubungan keluarga 1 orang lebih banyak ditemukan dibandingkan lebih 1 orang (64,4% banding 35,6%) dengan dominasi ayah (25,8%). Jenis kanker keluarga paling banyak bukan kanker paru dibandingkan kanker paru (85,4% banding 14,6%). Kesimpulan: Proporsi subjek kanker paru dengan riwayat kanker pada keluarga adalah 8,2%. Subjek dengan 1 anggota keluarga yang memiliki kanker paling banyak 64,4% dengan dominasi ayah 25,8%. Jenis kanker paru dengan riwayat kanker keluarga terbanyak adenokarsinoma 71%. Jenis kanker keluarga lebih banyak adalah bukan kanker paru 85,4%.

---

ABSTRACTBackground: The new cases and mortality of lung cancer are increasing. Smoking tobacco have a role play but only 15% smokers are suffering from lung cancer. Therefore, genetic factors thought to play a role in lung cancer. Many studies show a significant association with the risk of lung cancer in the family history of cancer.Objective: To determine the proportion of lung cancer?s subjects with a cancer history in the family.Methods: Using cross-sectional a descriptive observational study with the outpatient and inpatient lung cancer?s subject at Persahabatan Hospital, Jakarta started from January 1st, 2013 until April 30th, 2015.Results: The total subject of the study are 380 with the composition of men higher than women (72.9% vs 27.1 %) with a median is 56 and a minimum-maximum age is 20-86 (66). From those subjects, 65.3% are smokers with the most moderate IB is 33.2%. The most type cancer cells in group of Non Small Cell Lung Cancer Carcinoma (NSCLCC) is adenocarcinoma (73.4%). Most subjects diagnosed at an advanced stage either in groups of NSCLCC or Small Cell Lung Cancer Carcinoma (SCLCC). The subject?s proportion with the family cancer history is 8.2% in which male subjects are larger than females (5.8% vs 2.4%). A minimum-maximum age is 35-72 (37) and median 55. Smoker is only found in male 71% and the most type cancer cells is adenocarcinoma 71%. Family relation of the subjects found that 1 person is much more found than more 1 person (64.4% vs 35.6%) with dominated by father (25,8%). The type of cancer in the family is non lung cancer higher than lung cancer (85,4% vs 14,6%).Conclusions: The proportion of subjects with lung cancer in their family cancer is 8.2%. The most type family relation of the subjects is 1 person 64,4% with dominated by father 25,8%. The most type lung cancer cells which have family history cancer is adenocarcinoma 71%. The most type of cancer in the family is non lung cancer 64.4%.;Background: The new cases and mortality of lung cancer are increasing. Smoking tobacco have a role play but only 15% smokers are suffering from lung cancer. Therefore, genetic factors thought to play a role in lung cancer. Many studies show a significant association with the risk of lung cancer in the family history of cancer.Objective: To determine the proportion of lung cancer?s subjects with a cancer history in the family.Methods: Using cross-sectional a descriptive observational study with the outpatient and inpatient lung cancer?s subject at Persahabatan Hospital, Jakarta started from January 1st, 2013 until April 30th, 2015.Results: The total subject of the study are 380 with the composition of men higher than women (72.9% vs 27.1 %) with a median is 56 and a minimum-maximum age is 20-86 (66). From those subjects, 65.3% are smokers with the most moderate IB is 33.2%. The most type cancer cells in group of Non Small Cell Lung Cancer Carcinoma (NSCLCC) is adenocarcinoma (73.4%). Most subjects diagnosed at an advanced stage either in groups of NSCLCC or Small Cell Lung Cancer Carcinoma (SCLCC). The subject?s proportion with the family cancer history is 8.2% in which male subjects are larger than females (5.8% vs 2.4%). A minimum-maximum age is 35-72 (37) and median 55. Smoker is only found in male 71% and the most type cancer cells is adenocarcinoma 71%. Family relation of the subjects found that 1 person is much more found than more 1 person (64.4% vs 35.6%) with dominated by father (25,8%). The type of cancer in the family is non lung cancer higher than lung cancer (85,4% vs 14,6%).Conclusions: The proportion of subjects with lung cancer in their family cancer is 8.2%. The most type family relation of the subjects is 1 person 64,4% with dominated by father 25,8%. The most type lung cancer cells which have family history cancer is adenocarcinoma 71%. The most type of cancer in the family is non lung cancer 64.4%., Background: The new cases and mortality of lung cancer are increasing. Smoking tobacco have a role play but only 15% smokers are suffering from lung cancer. Therefore, genetic factors thought to play a role in lung cancer. Many studies show a significant association with the risk of lung cancer in the family history of cancer. Objective: To determine the proportion of lung cancer’s subjects with a cancer history in the family. Methods: Using cross-sectional a descriptive observational study with the outpatient and inpatient lung cancer’s subject at Persahabatan Hospital, Jakarta started from January 1st, 2013 until April 30th, 2015.Results: The total subject of the study are 380 with the composition of men higher than women (72.9% vs 27.1 %) with a median is 56 and a minimum-maximum age is 20-86 (66). From those subjects, 65.3% are smokers with the most moderate IB is 33.2%. The most type cancer cells in group of Non Small Cell Lung Cancer Carcinoma (NSCLCC) is adenocarcinoma (73.4%). Most subjects diagnosed at an advanced stage either in groups of NSCLCC or Small Cell Lung Cancer Carcinoma (SCLCC). The subject’s proportion with the family cancer history is 8.2% in which male subjects are larger than females (5.8% vs 2.4%). A minimum-maximum age is 35-72 (37) and median 55. Smoker is only found in male 71% and the most type cancer cells is adenocarcinoma 71%. Family relation of the subjects found that 1 person is much more found than more 1 person (64.4% vs 35.6%) with dominated by father (25,8%). The type of cancer in the family is non lung cancer higher than lung cancer (85,4% vs 14,6%).Conclusions: The proportion of subjects with lung cancer in their family cancer is 8.2%. The most type family relation of the subjects is 1 person 64,4% with dominated by father 25,8%. The most type lung cancer cells which have family history cancer is adenocarcinoma 71%. The most type of cancer in the family is non lung cancer 64.4%.]"

"ABSTRAKLatar Belakang: Penyakit paru obstruktif kronik (PPOK) merupakan salahsatupenyakit paru yang ditandai dengan obstruksi saluran pernapasan yangmengganggu pernapasan normal dengan age-adjusted death rate 41,2/100.000pada tahun 2009. Penyebab kematian tertinggi ketiga di dunia tahun 2008 dandiperkirakan akan menjadi penyakit tertinggi di dunia pada tahun 2030. Studi iniditujukan untuk melihat besarnya hubungan pajanan pestisida terhadap PPOKpada petani.Metode: Studi kasus kontrol dilakukan pada bulan April sampai Mei 2016 diPurworjeo. Sebanyak 66 kasus merupakan petani yang didiagnosis PPOK padatahun 2015 berdasarkan data register dan rekam medis, sedangkan 59 kontrolmerupakan tetangga korban yang bekerja sebagai petani dengan hasil ukurspirometer normal. Kasus dan kontrol diukur fungsi paru menggunakanspirometer dan COPD assessment test.Hasil: Analisis regresi logistik kuantitas (OR=0,75; 95% CI 0,318-1,754) dandurasi keterpajanan pestisida (OR=1,11; 95% CI 0,430-2,891) diadjust denganpotensial confounder tidak menunjukkan hubungan yang jelas. Pestisidaditemukan sebagai risiko PPOK berdasarkan lama kerja (OR=5,61; 95% CI1,124-27,990) setelah di-adjust oleh confounder (umur, IMT, APD, riwayatpenyakit, merokok, pajanan debu dan asapKesimpulan: Lama kerja ditemukan sebagai faktor risiko PPOK, tetapi tidakditemukan hubungan yang jelas antara kuantitas dan durasi terhadap PPOK. Alatpelindung diri sebaiknya digunakan terutama masker untuk mengurangi efektoksik terhadap paru

---

ABSTRACTBackground: Chronic obstructive pulmonary disease (COPD) is a term whichrefers to a large group of lung diseases characterized by obstruction of air flowthat interferes with normal breathing with age-adjusted death rate of41.2/100,000 in 2009. It causing 3rd highest of mortality worldwide in 2008 andestimated as the highest non communicable disease worldwide in 2030. This studyaimed to determine the relationship of pesticide exposure to COPD in farmerMethods: A case-control study performed between April to May 2016 inPurworejo. The case group were 66 farmer who suffered from COPD during 2015by medical record, while the control group were 59 farmer of cases neighbourwho tested by spirometer showed normal lung function. Both case and controlgroup was tested by spirometer and COPD assessment testResults: Logistic regression analysis of quantity (OR=0.75; 95% CI 0.318-1.754)and duration of spraying (OR=1.11; 95% CI 0.430-2.891) adjusted for allpotential confounders showed no clear associations. Pesticide remains a potentialhealth risk by duration of farming to COPD (OR=5,61; 95% CI 1,124-27,990)adjusted by confounders (age, BMI, PPE, history of resporatory illness, smokinghabit, dust and fumes exposure).Conclusion: Duration of farming found as risk factor of COPD, but no clearassociation of quantity and duration of spraying to COPD. PPE should be usedespecially mask along spraying process to reduce the risk of respiratory illness"

"Latar belakang: Pada akhir tahun 2019 di Wuhan, Cina ditemukan virus Corona baru yang menyebabkan klaster pneumonia. Coronavac (Sinovac) merupakan vaksin berisi SARS-CoV-2 inaktif yang dikembangkan di Cina. Data mengenai laporan KIPI dan kadar antibodi yang terbentuk pasca vaksinasi COVID-19 masih sangat terbatas.Tujuan penelitian: Mengetahui gambaran KIPI, demografi, komorbid dan kadar antibodi pada dokter spesialis paru dan residen paru pasca vaksinasi COVID-19 di RSUP Persahabatan.Metode penelitian: Deskriptif dengan studi potong lintang menggunakan alat bantu kuesioner.Hasil penelitian: Dari 79 subjek usia rerata adalah 35.32 SD7.332 terdiri dari 55.7% perempuan dan 35% laki- laki. Status gizi subjek 51% obesitas, 34% normal dan 15% gizi lebih. Komorbid subjek meliputi 13.9% asma, 8.9% diabetes mellitus, 6.3% untuk hipertensi dan dislipidemia, 2.5% bekas Tb, 1.3% untuk insufisiensi hepar, episode reflex syncope dan riwayat SVT. 45.6% subjek mengalami KIPI dengan gejala terbanyak nyeri lokal sebesar 38.9% dari total 36 subjek yang mengalami KIPI. 79 subjek mengalami serokonversi dengan median titer antibodi sebesar 29.28 dengan interquartile range 60.18.Kesimpulan:Kurang dari setengah subjek mengalami KIPI dari vaksinasi covid-19 dan subjek dengan KIPI hanya mengalami gejala ringan. Terjadi serokonversi pada seluruh subjek.

---

In late 2019 in Wuhan, China a novel Corona virus was found, causing pneumonia cluster. Coronavac (Sinovac) is an inactivated SARS-CoV-2 vaccines developed in China. AEFI data and antibody titers post Covid-19 vaccination are very limited.

Aims:

To determine AEFI incidences, demographic characteristic, comorbid and antibodi titers of pulmonologist and pulmonology resident post covid-19 vaccination at RSUP Persahabatan.

Methods:

Descriptive with cross sectional study using questionnaire.

Results:

Of 79 subjects, mean age was 35.32 SD7.332 included 55.7% female and 35% male. Nutritional status of subjects are 51% obese, 34% normal and 15% overweight. Subjects’comorbid varies as for asthma, diabetes mellitus, hypertension, dyslipidemia, post Tb, hepatic insufficiency, syncope reflex episode and history of SVT respectively 13.9%, 8.9%, 6.3%, 6.3%, 2.5%, 1.3%, 1.3%, 1.3%. 45.6% subjects experience AEFI with local pain accounts for the most symptom, 38.9% of total 36 subjects with AEFI. 79 subjects have seroconverted with antibody titers’median 29.28 and interquartile range 60.18.

Conclusions:

Less than half of the subjects experience AEFI from covid-19 vaccination and those who do only experience mild symptoms. Sercoconversion occurs in all subjects."

"Latar Belakang : Efusi pleura masif merupakan salah satu masalah pada tatalaksana kanker paru dan menyebabkan kematian. Pemasangan kateter intrapleura merupakan tatalaksana utama keganasan dengan efusi pleura masif. Kateter yang digunakan yaitu water sealed drainage, indwelling pleural catheter atau pigtail catheter. Water sealed drainage saat ini merupakan kateter yang terbanyak digunakan.Tujuan : Penelitian ini adalah penelitian pendahuluan untuk mengetahui penggunaan (toleransi dan efikasi) water sealed drainage, indwelling pleural catheter dan pigtail catheter pada penatalaksanaan kanker paru dengan efusi pleura masif.Metode : Penelitian observasional kohort retrospektif pada pasien kanker paru tegak jenis dengan efusi pleura masif yang terpasang kateter intrapleura (WSD, IPC atau pigtail catheter). Data diambil dari rekam medis Rumah Sakit Umum Pusat Persahabatan Jakarta pada periode 1 Januari 2012 sampai 31 Desember 2015 dan dilakukan penilaian tolerasi (komplikasi akut dan lanjut) dan efikasi (lama penggunaan, lama rawat dan alasan pencabutan) pemasangan kateter intrapleura.Hasil : Subjek penelitian 77 pasien dengan karakteristik laki-laki (55,8%), median usia 57 tahun, range 26-84 tahun, adenokarsinoma (84,4%) dan terapi kemoterapi (32,5%). Komplikasi akut sebesar 70,1%, komplikasi terbanyak nyeri lokasi pemasangan kateter (58,4%). Komplikasi lanjut sebesar 54,5%, komplikasi terbanyak nyeri lokasi kateter bertambah atau menetap (29,9%). Rerata lama rawat pasca pemasangan kateter 14,14 hari, median 10 hari dan range 1-72 hari. Rerata lama pemakaian kateter 55,98 hari, median 30 hari dan range 2-310 hari. Alasan pencabutan kateter terbanyak adalah produksi cairan minimal (46,75%).Kesimpulan : Toleransi dan efikasi penggunaan kateter intrapleura pada pasien kanker paru dengan efusi pleura masif cukup baik dan aman. Diperlukan penelitian kohort prospektif dengan jumlah sampel yang sama pada tiap kelompok kateter, sehingga penggunaan kateter dapat dianalisis perbandingannya dan penelitian dengan kelompok pembanding, contohnya tindakan pleurodesis, yang merupakan baku emas tatalaksana efusi pleura ganas.Background : Massive pleural effusion is one of the problems in lung cancer treatment that cause death. The main treatment of cancer patient with massive pleural effusion is the placement of intrapleural catheter. Catheters that can be used are water sealed drainage, indwelling pleural catheter or pigtail catheter. Currently, water sealed drainage is the most catheter used.Objective : This is a preliminary study which is aimed to assess tolerancies and efficacies of water sealed drainage, indwelling pleural catheter or pigtail catheter for treatment of lung cancer with massive pleural effusion.Methods : This study is a retroscpective observational cohort study. Subjects are lung cancer patients with massive pleural effusion and catheterized with intrapleural catheter (WSD, IPC or pigtail catheter). The datas were taken from medical record at RSUP Persahabatan between 1 January 2012-31 December 2015 and assessed for tolerancies (acute or late complication) and efficacies ((length of hospital admission after catheter placement, duration and the reason of retraction) of intrapleural catheterResults: Subjects of study are 77 patients, with characteristic, male (55,8%), median age 57 years old, range from 26 to 84 years old, adenocarcinoma (84,4%) and the most main therapy is chemotherapy (32,5%). Acute complication obtained in 70,1% patients, with the most common complication is pain in catheter location (58,4%). Late complication obtained in 54,5% patients with the most common complication is pain in the catheter location (29,9%). The mean of length of staying in hospital after the placement of catheter are 14,14 days, median 10 days, range from 1 to 72 days. The mean of duration of catheter placement is 55.98 days, median 30 days, range from 2 to 310 days. Minimal fluid production (46,75%) are the most reason of intrapleural catheter retraction.Conclusion: Tolerancies and efficacies of intrapleural catheter (WSD, IPC or pigtail catheter) in lung cancer patients with massive pleural effusion are quite good and safe. Prospective cohort studies are needed in the future to determine which type of intrapleural catheter is better for the treatment of massive pleural effusion in lung cancer patients and studies with comparison group for example pleurodesis, which is the gold standard for treatment of malignant pleural effusion."