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"Pendahuluan: Nyeri kronik merupakan fenomena biopsikososial yang kompleks yang berlangsung lebih dari 3 hingga 6 bulan dengan intensitas nyeri yang persisten. Merupakan salah satu masalah kesehatan terbesar di dunia.. Hasil penelitian multisenter 14 Rumah Sakit pendidikan yang dilakukan Pokdi Nyeri PERDOSSI tahun 2002 didapatkan 4.456 kasus nyeri dimana 9,5% diantaranya adalah nyeri neuropatik. Nyeri neuropatik dikenal sebagai salah satu kumpulan gejala yang sulit diidentifikasi dengan tatalaksana yang suboptimal. Tujuan: Didapatkannya instrumen kuesioner painDETECT versi Indonesia yang valid dan reliabel. Metode: Penelitian dengan menggunakan studi validasi transkultural ISPOR disertai analisis validasi kriteria dan uji reliabilitas konsistensi internal dan tes retes secara guided interview menggunakan kuesioner painDETECT. Hasil: Didapatkan 150 sampel dengan nyeri kronik berdasarkan skor kuesioner painDETECT versi Indonesia, 75 pasien dengan nyeri nosiseptif, 42 pasein dengan nyeri campuran dan 33 pasien dengan nyeri neuropatik. Pada analisis validasi kriteria didapatkan korelasi tinggi dengan instrumen standar emas LANSS (r= 0,082,p<0,001), AUC 85,5%, sensitivitas 78,3% dan spesifisitas 78,7% dengan titik potong optimal ≥17. Pada uji reliabilitas konsistensi internal didapatkan nilai Alpha Cronbach 0,710 dan nilai reliabilitas tes retes 0,96. Simpulan: Didapatkannya kuesioner painDETECT versi Indonesia yang valid dan reliabel dengan nilai sensitivitas dan spesifisitas yang baik dalam menapis komponen nyeri neuropatik.

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Background: Chronic pain is a complex biospsychosocial phenomena. Pain that lasting more than 3 to 6 months with persistence intensity. Representing one of the biggest health problem in the world. Based on the results of a multicentre study in 14 Education Hospital, PERDOSSI Pain Study Group conducted in 2002 found 4,456 pain cases in which 9.5% were neuropathic pain. Whereas neuropathic pain is known as one of the hardest to overcome which are often missed identified and causing a suboptimal treatment.

Objective: To develop an Indonesian version of PainDETECT Questionnaire (PDQ-Ina) and assess its validity and reliability.

Methode: Using ISPOR transcultural validation study and criteria validation analysis followed with reliability internal consistency test and test retest based on PDQ guided interview.

Result: There were 150 subjects with chronic pain. Divided in to 3 types of group based on Indonesian version PDQ scoring, 75 patients having nociceptive pain, 42 were mixed pain and 33 patients having neuropathic pain. Within validation criteria analysis there were high correlation between PDQ-Ina with LANSS instrument as gold standard (r= 0,082,p<0,001), AUC 85,5%, sensitivity 78,3% and specificity 78,7% with the optimal cut off point ≥17. The reliability of internal consistency Cronbach’s Alpha value were 0,710 and the test retest realibility were 0,96.

Conclusion: The Indonesian version of the PDQ is a valid and reliable scale and have a good sensitivity and specificity to be used to determine neuropathic component of chronic pain."

"ABSTRAK Perilaku keselamatan kerja pada pekerja Usaha Mikro Kecil dan Menengah (UMKM)khususnya pengolahan kayu di Indonesia masih kurang baik, ditandai dengan masih tingginyaangka disabilitas akibat kecelakaan kerja. Tujuan penelitian ini adalah diketahui dandiperolehnya faktor-faktor yang mempengaruhi perilaku keselamatan kerja pada pekerjaUMKM pengolahan kayu. Studi kualitatif menggunakan wawancara mendalam dan kelompok diskusi terfokus denganpedoman wawancara semi-struktur pendekatan teori Green di 2 perusahaan informalpengolahan kayu. Wawancara mendalam dilakukan pada 2 orang bagian manajemen, 2 orangmandor, 4 orang pekerja. Kelompok diskusi terfokus dilakukan pada 2 kelompok dengan 5orang pekerja di setiap kelompok. Pekerja pengolahan kayu memiliki persepsi yang cukup baik mengenai perilaku keselamatankerja hal ini dikarenakan memiliki pengalaman bekerja cukup lama meskipun berlatarbelakang pendidikan rendah. Sikap dan perilaku yang belum mencerminkan perilakukeselamatan kerja dipengaruhi motivasi, minat, role model, kesiapan, kebijakan danpengawasan yang masih kurang. Mandor masih kurang ketat bertindak sebagai role modeldan melakukan pengawasan terhadap pekerja di lapangan. Manajemen perusahaan sudahmelakukan penyediaan sarana dan prasarana sesuai standar tetapi tidak diikuti oleh adanyakebijakan, peraturan, pelatihan serta reward dan punishment. Persepsi baik berperilaku keselamatan kerja pada pekerja pengolahan kayu dalam mencegahkecelakaan kerja dipengaruhi oleh pengetahuan, pengalaman dan sarana prasarana standaryang cukup baik. Tetapi kurangnya motivasi, minat, contoh teladan, kesiapan danpengawasan mempengaruhi sikap dan perilaku keselamatan kerja yang kurang baik.Manajemen dan mandor yang kurang menerapkan kebijakan, peraturan, pelatihan, rewarddan punishment juga mempengaruhi perilaku keselamatan kerja bagi para pekerja pengolahankayu.ABSTRACT Workers in MSME lack good safety behavior specially carpenters in Indonesia, marked by ahigh incidence of disability caused by occupational accidents. The aim of this study is to identify influencing factors to workers?s safety behavior of carpenter in the micro, small andmedium enterprises (MSME). A Qualitative study was conducted using in-depth interviews and focus group discussion withsemi-structured guidelines from Green theory, conducted in 2 MSME carpenter industry. Indepthinterviews involving 2 management staffs, 2 supervisors and 4 carpenters. Focusgroup discussion was conducted with 2 groups, each consisting of 5 carpenters in . Adequacy of good safety behavior perceptions was found, due to carpenter?s long experience,although they have low educational level. Carpenter?s attitude and behavior did not complywith safe behavior, influenced by lack of motivation, interest, role model, readiness, policyand supervision. Supervisors were not regarded as role models and are weak in supervision.Management already provides standar infrastructure and facilities, but lack of policy,regulation, training also reward and punishment system. The micro, small and medium enterprises (MSME) carpenter?s good perceptions tooccupational accident prevention influenced by knowledge, experience and standardinfrastructure and facilities, but Carpenters?s lack of motivation, interest, role model,readiness and supervision influenced low attitude and lack of safety behavior.Managementand supervisor?s also fail to support carpenter?s safety behavior by not implementing policy,regulation, training, reward and punishment system.;Workers in MSME lack good safety behavior specially carpenters in Indonesia, marked by ahigh incidence of disability caused by occupational accidents. The aim of this study is to identify influencing factors to workers?s safety behavior of carpenter in the micro, small andmedium enterprises (MSME). A Qualitative study was conducted using in-depth interviews and focus group discussion withsemi-structured guidelines from Green theory, conducted in 2 MSME carpenter industry. Indepthinterviews involving 2 management staffs, 2 supervisors and 4 carpenters. Focusgroup discussion was conducted with 2 groups, each consisting of 5 carpenters in . Adequacy of good safety behavior perceptions was found, due to carpenter?s long experience,although they have low educational level. Carpenter?s attitude and behavior did not complywith safe behavior, influenced by lack of motivation, interest, role model, readiness, policyand supervision. Supervisors were not regarded as role models and are weak in supervision.Management already provides standar infrastructure and facilities, but lack of policy,regulation, training also reward and punishment system. The micro, small and medium enterprises (MSME) carpenter?s good perceptions tooccupational accident prevention influenced by knowledge, experience and standardinfrastructure and facilities, but Carpenters?s lack of motivation, interest, role model,readiness and supervision influenced low attitude and lack of safety behavior.Managementand supervisor?s also fail to support carpenter?s safety behavior by not implementing policy,regulation, training, reward and punishment system.;Workers in MSME lack good safety behavior specially carpenters in Indonesia, marked by ahigh incidence of disability caused by occupational accidents. The aim of this study is to identify influencing factors to workers?s safety behavior of carpenter in the micro, small andmedium enterprises (MSME). A Qualitative study was conducted using in-depth interviews and focus group discussion withsemi-structured guidelines from Green theory, conducted in 2 MSME carpenter industry. Indepthinterviews involving 2 management staffs, 2 supervisors and 4 carpenters. Focusgroup discussion was conducted with 2 groups, each consisting of 5 carpenters in . Adequacy of good safety behavior perceptions was found, due to carpenter?s long experience,although they have low educational level. Carpenter?s attitude and behavior did not complywith safe behavior, influenced by lack of motivation, interest, role model, readiness, policyand supervision. Supervisors were not regarded as role models and are weak in supervision.Management already provides standar infrastructure and facilities, but lack of policy,regulation, training also reward and punishment system. The micro, small and medium enterprises (MSME) carpenter?s good perceptions tooccupational accident prevention influenced by knowledge, experience and standardinfrastructure and facilities, but Carpenters?s lack of motivation, interest, role model,readiness and supervision influenced low attitude and lack of safety behavior.Managementand supervisor?s also fail to support carpenter?s safety behavior by not implementing policy,regulation, training, reward and punishment system."

"Latar belakang: Dalam beberapa dekade terakhir, dunia kerja industri transportasi telah mengalami perubahan luar biasa seperti halnya bidang pekerjaan lain. Tuntutan operasional transportasi 24 jam kerja dalam sehari dan 7 hari kerja dalam seminggu menciptakan risiko keselamatan dan kesehatan yang berkaitan dengan rasa kantuk, yaitu suatu kondisi yang diketahui mengganggu kinerja saat mengemudi dan merupakan salah satu penyebab timbulnya kecelakaan dan kematian saat berlalu lintas. Penelitian ini bertujuan untuk mengidentifikasi risiko mengantuk pada pengemudi bus jarak jauh dan faktor-faktor yang berhubungan.Metode: Penelitian ini menggunakan desain studi potong lintang. Dua ratus satu pengemudi yang bekerja di hari libur panjang nasional diikutsertakan dalam penelitian. Data sekunder didapatkan dari kuesioner dan hasil pemeriksaan medis pengemudi bus pada liburan akhir tahun 2018 oleh Dinas Kesehatan Pemerintah Provinsi Daerah Khusus Ibukota Jakarta.Hasil: Proporsi kantuk pada pengemudi bus jarak jauh adalah 9,5%. Mengemudi lebih dari 1.001 km dalam satu kali perjalanan dengan ORs=7.927 (CI 95%=2.184-28.769; p=0.002) dan kondisi kelelahan dengan ORs=3.824 (CI 95%=1.393-10.499; p=0.009) merupakan faktor determinan utama penyebab rasa kantuk pada pengemudi bus jarak jauh. Jumlah trayek selama sebulan dan faktor individu seperti usia, riwayat hipertensi, dan riwayat diabetes melitus tidak memiliki hubungan yang signifikan secara statistik dengan kejadian kantuk (p>0.05).Kesimpulan: Sebanyak 9,5% pengemudi bus jarak jauh mengalami kecenderungan mengantuk. Faktor jarak perjalanan dan kelelahan merupakan faktor yang terkait dengan timbulnya risiko kantuk pada pengemudi bus jarak jauh (R2=0.235).

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Background: As is the case with many other occupations, the work organization of transport operators has undergone tremendous changes over the past several decades. Transportation’s 24 hours in a day an 7 days in a week operational demands create safety and health risks related to sleepiness, a condition that is known to impair driving performance and causes of motor vehicle crashes and fatalities. This study aims to identify the risk of sleepiness in long distance commuter bus drivers and its associated factors.

Method: This study used a cross sectional study design. Two hundred and one drivers who are working in long national holidays were involved in this study. The secondary data was gathered from questionnaires and medical examination of bus driver in year-end holidays 2018 by Jakarta Provincial Health Office.

Result: The proportion of sleepiness in long distance commuter bus drivers 9.5%. Driving more than 1,001 km in a single commute trip with ORad=7.927 (95%CI=2.184-28.769; p=0.002) and fatigue condition with ORad=3.824 (95%CI=1.393-10.499; p=0.009) are dominant determinants of sleepiness in long distance commuter bus drivers. Monthly number of trip and individual factors such as age, history of hypertension, and history of diabetes mellitus do not have a statistically significant relationship with the incidence of drowsiness (p>0.05).

Conclusion: Nine point five percent of long distance commuter bus drivers is experiencing sleepiness. Trip distance and fatigue are associated factors with the risk of sleepiness in long distance commuter bus drivers (R2=0.235)."

"Latar belakang: Perilaku penggunaan Alat Pelindung Diri (APD) pada pekerja sektor konstruksi di Indonesia masih kurang baik, ditandai dengan masih tingginya angka kematian dan disabilitas akibat kecelakaan kerja. Penelitian ini bertujuan untuk mengetahui mengapa dan bagaimana fenomena tersebut terjadi dan faktor-faktor yang mempengaruhi penggunaan APD pada pekerja konstruksi. Metode: Studi kualitatif menggunakan Fokus Grup Diskusi (FGD) dan wawancara mendalam dengan pedoman wawancara semi-struktur pada 13 informan pekerja konstruksi, 3 orang mandor, 4 orang manajemen proyek serta 2 orang manajemen perusahaan sebuah perusahaan jasa konstruksi nasional. Pendekatan yang digunakan adalah pendekatan fenomenologis. Hasil: Pekerja konstruksi mengakui bahwa tidak atau tidak selalu memakai APD, khususnya yang rutin harus digunakan. Sikap pekerja yang kurang baik dipengaruhi oleh pengetahuan terbatas, konsep diri rendah (persepsi, intensi dan pengalaman), status pekerja serta tingkat pendidikan yang rendah. Manajemen proyek hingga manajemen perusahaan berperan dalam penyediaan, inventarisasi APD yang kurang memadai, peraturan yang tidak dijalankan dengan ketat, pelatihan yang tidak diberikan kepada pekerja. Manajemen proyek dan mandor juga bertanggung jawab terhadap pengawasan, namun implementasi di lapangan masih longgar. Kesimpulan: Perilaku pekerja konstruksi dalam penggunaan Alat Pelindung Diri (APD) terutama dipengaruhi oleh tingkat pendidikan yang rendah dan status kerja. Kurangnya pengawasan, pelatihan serta regulasi dari manajemen berkontribusi terhadap perilaku penggunaan APD pada pekerja.

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Backgrounds: Construction workers’ lack of good behavior towards Personal Protective Equipment (PPE) usage, marked by high incidence of mortality and disability caused by occupational accidents in Indonesia. This research aim is to study why and how this phenomenon occured among construction workers and factors infulencing workers’ behavior on PPE usage.

Method: Qualitative study was conducted ,consisted of focus group discussions and in-depth interviews with semi-structured quidelines involving 13 construction workers, 3 supervisors, 4 project management staffs and 2 company management staffs from a national construction company . Conceptual framework used was phenomenological study.

Results: Construction workers admitted that PPE did not always used at work, particularly those routinely have to be used. Lack of good PPE usage behavior caused by limited knowledge of PPE functions, workers’ low self concept (perception, intention, and experience), low educational level, labor status,. Project management to company management took part in lack of PPE supply, inventory, regulations and training that did not meet the requirements. Project management and supervisors also contributed to supervision, although the implementation still loose.

Conclusion: Construction workers behavior of PPE usage particularly caused by low educational level and labor status. Management’s lack of supervision, training, and regulation contributed to workers’ PPE usage behavior."

"Latar Belakang: Meningitis Cryptococcus merupakan infeksi oportunistik penting pada penderita AIDS dan menduduki urutan ke tiga infeksi otak. Angka kejadian meningitis Cryptococcus secara umum sebesar 957 900 kasus per tahun. Angka kejadian di Indonesia sekitar 5-30%, dan di Jakarta sebesar 21,9%. Angka kejadian tersebut tampaknya belum mencerminkan kondisi sebenarnya, mungkin karena gejala klinis yang tidak khas dan diagnosis pasti memerlukan cairan otak yang sulit didapat. Diperlukan metode lain untuk membantu keputusan klinis saat pungsi lumbal belum dapat dilakukan sehingga prevalensi kriptokokosis yang sesungguhnya diketahui. Tujuan: Mengetahui prevalensi kriptokokosis pada pasien terinfeksi HIV pra ARV di UPT HIV RSCM. Metode penelitian: Studi potong lintang dilakukan sejak Mei - Juli 2013. Subjek penelitian adalah pasien terinfeksi HIV pra ARV. Antigen serum Cryptococcus diperiksa dengan metode lateral flow immunoassay (LFA). Hasil: Dari 78 subjek penelitian, sebanyak 59% adalah laki-laki, berusia 18-68 tahun. Kadar CD4 berkisar antara 2-754 sel/mm3, dan 68% dengan CD4 <200 sel/mm3. Sebanyak lima (6,4%) subjek positif antigen serum Cryptococcus, dua diantaranya dilakukan pungsi lumbal dengan hasil tidak dijumpai Cryptococcus. Kedua subjek ini mendapat terapi flukonazol oral dan hidup sampai saat ini. Tiga subjek lain menolak tatalaksana dan meninggal empat minggu kemudian. Simpulan: Prevalensi kriptokokosis pada pasien terinfeksi HIV pra ARV di UPT HIV-RSCM sebesar 6,4%.

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Background: Cryptococcal meningitis is prominent opportunistic infections occur in PWHIV and seats as the third most frequent brain infection. In general, Meningitis Cryptococcal reach 957 900 cases per year. It is estimated that the prevalence rate is 21.9% and 5 - 30% for Jakarta and Indonesia, respectively. It does not reflect the real number, which might be due to unspecific clinical symptoms. In making diagnosis, it requires cerebrospinal fluid that is challenging to obtain. Other method is needed to feeding clinical decision, when lumbal puncture cannot be performed. Thus, real Cryptococcal prevalence is known.

Aim: To ascertain Cryptococcal prevalence among pre-ART PWHIV at Integrated HIV Clinic, Cipto Mangunkusumo Hospital.

Method: This study using cross-sectional design conducted from May – July 2013 at the HIV clinic. Participants of the study were patients who have not started ART. Cryptococcal serum antigen was tested using LFA.

Results: Of 78 participants, 59% male, age 18 - 68 year old. CD4 countvaried from 2 - 754 cell/mm3, where 68% had CD4 count <200 cell/mm3. Five participants (6.4%) were positive to Cryptococcal serum antigen, whereas two run lumbal puncture which showing negative result for Cryptoccus. They received oral fluconazole treatment and have survived until present. The rest refused thetreatment and passed away four weeks later.

Conclusion: Cryptococcosis prevalence among pre-ART PWHIV at Integrated HIV clinic, Cipto Mangunkusumo Hospital is 6.4%."

"Latar belakang. Depresi merupakan salah satu gangguan psikiatri yang sering terjadi pada pasien epilepsi. Prevalensinya adalah 20-80%. Depresi bukan merupakan suatu pemeriksaan yang rutin dilakukan di poliklinik neurologi karena membutuhkan waktu yang cukup lama, sehingga banyak pasien yang tidak terdiagnosis dan akhirnya tidak terobati, untuk itu diperlukan pemeriksaan yang singkat. The Neurological Disorders Depression Inventory for-Epilepsi (NDDI-E) merupakan pemeriksaan skrining depresi yang terdiri dari 6-aitem. Tujuan. Menentukan akurasi dan titik potong NDDI-E versi Indonesia sebagai skrining depresi pada pasien epilepsi dewasa. Metode. Penelitian uji diagnostik yang dilakukan di poliklinik epilepsi RSCM. Pemeriksaan dilakukan pada semua pasien epilepsi yang memenuhi kriteria inklusi. Pasien mengisi sendiri formulir NDDI-E tanpa bantuan orang lain. Kemudian dilakukan pemeriksaan the International Neuropsychiatric Interview Mini ICD-10 (MINI-ICD10) sebagai standar baku. Hasil. Dari 105 orang subyek penelitian terdapat 23 orang mengalami gangguan depresi mayor berdasarkan MINI-ICD 10. Didapatkan kurva Receiver Operating Characteristic (ROC) yang mendekati 100%, titik potong 11, dengan Sensitifitas 91,3% Spesifisitas 89% PPV 70% dan NPV 97,3%. Secara statistik NDDI-E versi Indonesia masuk dalam klasifikasi yang kuat, karena nilai Area Under the Curve (AUC) 97,5% dengan interval kepercayaan (95%CI 95%-99%). Kesimpulan. NDDI-E versi Indonesia memiliki nilai akurasi yang tinggi untuk menentukan gangguan depresi mayor pada pasien epilepsi dewasa pada titik potong 11.

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Background. Depression is a common psychiatric disorder in epilepsy. The prevalence is 20-80%. The depression is not a routinely assessed in neurology clinics, because the assestment takes a long time. So, many patients are under diagnosed and untreated. The Neurological Disorders Depression Inventory for-Epilepsy (NDDI-E) is a depression screening examination consist of only 6-aitem.

Purpose. To determine the accuracy and cut-off point of NDDI-E Indonesian version as a screening depression examination for adult epilepsy patients.

Method. Diagnostic test study was conducted at epilepsy clinic on RSCM. All the epilepsy patient who met the inclusion criteria was examined. The patient took the NDDI-E Indonesian version as a self assesment. Then there were assest with used the International Neuropsychiatric Interview Mini ICD-10 (MINI-ICD10) as a gold standar.

Results. From the 105 subjects, there were 23 people suffered from major depression by MINI-ICD10. Receiver Operating Characteristic (ROC) curve obtained which is close to 100%, cut-off point at 11, with Sensitivity 91.3% Specificity 89% PPV 70% and NPV of 97.3%. It was statistically classified as strong because the value of Area Under the Curve (AUC) is 97.5% with a confidence interval (95% CI 95% -99%).

Conclusion. NDDI-E Indonesian version has a high accuracy to determine major depressive disorder in adult epilepsy patients with the cut-off point at 11."

"[ABSTRAK Nama Hendra SamantaProgram Studi Pendidikan Dokter Spesialis NeurologiJudul Protein S 100B sebagai prediktor tingkat keparahan cedera kepala Latar Belakang Cedera kepala merupakan salah satu masalah kesehatan masyarakat yang serius yang dapat menyebabkan kematian kecacatan fisik dan kecacatan mental Cedera kepala dapat menyebabkan sel astrosit rusak sehingga mengeluarkan protein S 100B yang dapat dideteksi didalam darah perifer sehingga dapat dipakai untuk memprediksi tingkat keparahan cedera kepala yang terjadi Penelitian ini bertujuan untuk mencari hubungan antara kadar protein S 100B dengan tingkat keparahan cedera kepala Metode Desain penelitian adalah potong lintang untuk mengetahui kadar protein S 100B pada pasien cedera kepala akut onset kurang dari 24 jam Subyek penelitian sejumlah 85 pasien yang datang berobat ke Instalasi Gawat Darurat RSCM sejak bulan maret ndash juni 2015 Dilakukan penilaian GCS lamanya tidak sadarkan diri lamanya amnesia pasca trauma dengan bantuan alat TOAG pemeriksaan CT Scan dan pemeriksaan serum protein S 100B Hasil Didapatkan kadar rerata protein S 100B serum 0 77 g L rerata durasi amnesia 21 22 jam rerata nilai GCS 13 Terdapat perbedaan kadar protein S 100B pada CKR rerata 0 4175 dibandingkan dengan pada CKS dan CKB 1 0722 p 0 020 nilai titik potong kadar protein S 100B pasien yang meninggal 0 765 g L p 0 002 Simpulan Kadar rerata protein S 100B pada cedera kepala ringan lebih rendah dibandingkan dengan kadar protein S 100B pada cedera kepala sedang dan berat semakin tinggi kadar protein S 100B akan semakin tidak baik keluaran pasien cedera kepala ABSTRACT Name Hendra SamantaStudy program Neurology Specialization Educational ProgrammedTitle Protein S 100B as Predictor Severity Traumatic Brain Injury Background Traumatic brain injury is still a serious community health problem can cause death physical and mental disability Protein S 100B release from destructive astrocyte from brain injury and detected in the peripheral blood so that protein S 100B can serve as predictor of severity traumatic brain injury This research aimed to find association between protein S 100B with traumatic brain injury severity Method This was a cross sectional study focusing to protein S 100B value from acute traumatic brain injury patients with onset 24 hours Eighty five patients were recruited from emergency room RSCM GCS value duration of post traumatic amnesia with TOAG tools duration loss of consciousness brain CT scan and concentration serum protein S 100B were record Results The mean concentration serum Protein S 100B were 0 77 mean PTA duration were 21 22 hours and the mean GCS were 13 There is a significant differentiation value of concentration protein S 100B from mild trumatic brain injury compare moderate and severe traumatic brain injury p 0 020 cut off point for death patients was 0 765 g LConclusion The mean serum Protein S 100 B from mild trumatic brain injury lower than moderate and severe traumatic brain injury higher consentration of protein S 100B have bad outcome ;ABSTRACT Name Hendra SamantaStudy program Neurology Specialization Educational ProgrammedTitle Protein S 100B as Predictor Severity Traumatic Brain Injury Background Traumatic brain injury is still a serious community health problem can cause death physical and mental disability Protein S 100B release from destructive astrocyte from brain injury and detected in the peripheral blood so that protein S 100B can serve as predictor of severity traumatic brain injury This research aimed to find association between protein S 100B with traumatic brain injury severity Method This was a cross sectional study focusing to protein S 100B value from acute traumatic brain injury patients with onset 24 hours Eighty five patients were recruited from emergency room RSCM GCS value duration of post traumatic amnesia with TOAG tools duration loss of consciousness brain CT scan and concentration serum protein S 100B were record Results The mean concentration serum Protein S 100B were 0 77 mean PTA duration were 21 22 hours and the mean GCS were 13 There is a significant differentiation value of concentration protein S 100B from mild trumatic brain injury compare moderate and severe traumatic brain injury p 0 020 cut off point for death patients was 0 765 g LConclusion The mean serum Protein S 100 B from mild trumatic brain injury lower than moderate and severe traumatic brain injury higher consentration of protein S 100B have bad outcome , ABSTRACT Name Hendra SamantaStudy program Neurology Specialization Educational ProgrammedTitle Protein S 100B as Predictor Severity Traumatic Brain Injury Background Traumatic brain injury is still a serious community health problem can cause death physical and mental disability Protein S 100B release from destructive astrocyte from brain injury and detected in the peripheral blood so that protein S 100B can serve as predictor of severity traumatic brain injury This research aimed to find association between protein S 100B with traumatic brain injury severity Method This was a cross sectional study focusing to protein S 100B value from acute traumatic brain injury patients with onset 24 hours Eighty five patients were recruited from emergency room RSCM GCS value duration of post traumatic amnesia with TOAG tools duration loss of consciousness brain CT scan and concentration serum protein S 100B were record Results The mean concentration serum Protein S 100B were 0 77 mean PTA duration were 21 22 hours and the mean GCS were 13 There is a significant differentiation value of concentration protein S 100B from mild trumatic brain injury compare moderate and severe traumatic brain injury p 0 020 cut off point for death patients was 0 765 g LConclusion The mean serum Protein S 100 B from mild trumatic brain injury lower than moderate and severe traumatic brain injury higher consentration of protein S 100B have bad outcome ]"