Hasil Pencarian  ::  Simpan CSV :: Kembali

"Dalam beberapa tahun terakhir, angka kejadian alergi terus meningkat tajam baik di dalam negeri maupun luar negeri. World Allergy Organization (WAO) menyebutkan 22% penduduk dunia menderita alergi dan terus meningkat setiap tahun. Alergi makanan merupakan suatu kondisi yang disebabkan oleh reaksi IgE terhadap bahan (zat kimia) makanan. Alergi makanan dapat mengganggu fungsi otak dan sistem organ tubuh serta mempengaruhi kualitas hidup seseorang.Penelitian ini dilakukan untuk mengetahui gambaran sensitivitas terhadap alergen makanan di Poli Alergi Imunologi Rumah Sakit Cipto Mangunkusumo (RSCM) pada tahun 2007. Data yang digunakan merupakan data sekunder dari 208 responden yang memiliki rekam medik dan yang melakukan tes tusuk kulit (skin prick test) di Poli Alergi Imunologi RSCM tahun 2007. Analisis univariat dilakukan untuk mendeskripsikan jenis alergen makanan pada kelompok anakdan dewasa. Sebesar 49% responden sensitif terhadap alergen makanan. Jenis makanan yang paling banyak menyebabkan alergi pada anak-anak dan dewasa berturut-turut adalah udang, putih telur dan maizena. Susu sapi dan tepung terigu merupakan jenis makanan yang paling banyak menyebabkan alergi hanya pada anak-anak, sedangkanpada dewasa, makanan yang paling banyak menyebabkan alergi adalah kepiting.

---

AbstractIn recent years, the occurrence of allergy continues to increase rapidly both domestically and globally. World Allergy Organization (WAO) revealed that 22% of the world population suffersfrom allergies, and this number increases every year. Food allergy is a condition caused by the reaction of IgE against substances (chemicals) in food. Food allergy can interfere with brain function and body organ systems as well as affect the quality of life. The purpose of this study is to know the level of sensitivity of food allergens in the Immunology Allergy Poly RSCM in 2007. Data were collected from 208 patients who have medical records and went through skinprick tests in the Immunology Allergy Clinic RSCM in 2007. Univariate analysis was performed to describe the types of food allergens within groups of children and adults. Around 49% of the respondents were sensitive to food allergens. The types of foods that caused the most allergies for children and adults are respectively shrimp, egg white andcornstarch. Cow's milk and wheat flour are the types of food that caused most allergies for children only, whereas for adults, the food that caused the most allergies is crab."

"Background: nowadays, specific IgE measurement has been conducted in Indonesia, however there is still lack of data regarding diagnostic test to detect inhalant allergen in patients with respiratory allergies.This study aimed to determine the accuracy of specific IgE test in diagnosing specific sensitization of inhalant allergen in patients with respiratory allergies.Methods: this was a cross sectional study in patients with respiratory allergies and part of epidemiology study regarding to specific IgE sensitization in Allergy-Immunollogy Division, Cipto Mangunkusumo Hospital, Jakarta within November-December 2016. Measurement of specific IgE sensitization using Immunoblot method (Euroline, Euroimmun AG, Germany). The tested allergen is house dust mites Dermatophagoides pteronyssinus (Der p), Dermatophagoides farinae (Der f), Blomia tropicalis (Blo t) and cockroach Blatella germanica (Bla g). The result is compared with gold standard, skin prick test. The diagnostic result includes sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (LR+), and negative likelihood ratio (LR-).Results: a total of 101 patients were enrolled; 77 (76.2%) were women. Patients mean age was 38.8 years old. Based on SPT, sensitization was highest for Blo t (76.2%), followed by Der p (70.3%), Der f (69.3%), and Bla g (41.6%). Specific IgE-sensitization was highest for Der f (52.9%), followed by Der p (38.2%), Blo t (33.3%) and Bla g (10.8%). Der p allergen had 50.7% sentivity, 90% specificity, 92.3% PPV, 43.5% NPV, 5.1 LR+ and 0.1LR-. Der f showed 71.4% sensitivity, 87.1% specificity, 82.6% PPV, 57.4% NPV, 5.5 LR+ and 0.3 LR-. Blo t allergen had 41.6% sensitivity, 91.7% specificity, 94.1% PPV, 32.8% NPV, 5.0 LR+, and 0.6 LR-. Bla g allergen had 23.8% sensitivity, 98.3% specificity, 90.9% PPV, 64.4% NPV, 14.5 LR+ and 0.8 LR-.Conclusion: serum specific IgE testing to common inhalant allergen in patients with respiratory allergy showed only low-to-moderate sensitivity, but high specificity and PPV. This new assay can be used to diagnose allergen sensitization in the population with high prevalence of TDR and cockroach."