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Ricky Roosdiana Dewi
"LSTV merupakan variasi vertebra yang prevalensinya bervariasi di dunia. Menurut konsep Bertolotti rsquo;s syndrome, LSTV berhubungan dengan nyeri punggung bawah dan sebagian besar nyeri ini disebabkan oleh penyakit degenerasi diskus. Sayangnya, hubungan keduanya masih kontroversial. Pada penelitian ini dilakukan analisis hubungan LSTV dengan penyakit degenerasi diskus lumbosakral berdasarkan gambaran CT scan. Penelitian menggunakan desain potong lintang dengan jumlah sampel 161 pasien. Data sampel diambil dari database sekunder CT scan abdomen di Departemen Radiologi RSUPNCM dengan berbagai indikasi klinis dan dianalisis menggunakan uji statistik chi-square. Hasilnya, sebanyak 25,5 individu yang diidentifikasi memiliki LSTV dan sebanyak 77,0 individu mengalami degenerasi diskus lumbosakral. Meskipun begitu, uji hipotesis menunjukkan tidak terdapat hubungan bermakna antara LSTV dengan penyakit degenerasi diskus lumbosakral p>0,05.

LSTV is one of vertebra variation which has variation prevalent in the world. Based on Bertolotti rsquo s syndrome concept, LSTV is suggested related to low back pain and most of this pain is come from degeneretaive disc disease. Unfortunately, Bertolotti rsquo s syndrome concept is still debated around the world. This research will analyze the relationship between LSTV and degenerative lumbosacral disc disease based on CT Scan imaging. The research use cross sectional design with 161 samples. The data used were collected from abdominal seconday CT scan database in Radiology Department in RSUPNCM with any clinical indications and analyzed using chi square test. The result shows 25,5 subject has LSTV and 77,0 subject has degenerative lumbosacral disc disease. Although, hypothesis test shows that there is no significant relationship between LSTV and degenerative disc disease p 0,05.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2016
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UI - Skripsi Membership  Universitas Indonesia Library
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Hanna Marsinta Uli
"Mortalitas penderita artritis reumatoid(AR) yang cukup tinggi disebabkan oleh penyakit kardiovaskular akibat aterosklerosis.Penelitian ini bertujuan untuk mengetahui sensitivitas dan spesifitas skor kalsifikasi arkus aorta di foto polos toraks berdasarkan klasifikasi Ogawa dalam mendeteksi aterosklerosis pada penderita AR. Penelitian ini menggunakan desain potong lintang pada 76 pasien AR di Poliklinik Reumatologi RSUPN Cipto Mangunkusumo. Hasil penelitian menunjukkan sensitivitas 25% dan spesifitas 91,7% pada titik potong skor Ogawa 3,125%, dengan demikian lebih baik untuk mendeteksi pasien AR tanpa aterosklerosis. Pasien AR dengan kalsifikasi arkus aorta kemungkinan memiliki aterosklerosis sebesar 3,7 kali daripada pasien AR tanpa kalsifikasi arkus aorta.

Mortality of rheumatoid arthritis (RA) patients which is quite high caused by cardiovascular disease due to atherosclerosis. This study aims to determine the sensitivity and specificity of the aortic arch calcification score on plain chest X-ray based on classification Ogawa in detecting atherosclerosis in RA patients. This study used a cross-sectional design in 76 patients at the Rheumatology Division Cipto Mangunkusumo Hospital. The results showed a sensitivity of 25% and specificity of 91.7% at the cut off point Ogawa scores 3.125%, thus it is better to detect RA patients without atherosclerosis. The possibility of arthritis rheumatoid patients with aortic arch calcification having atherosclerosis by 3.7 times than RA patients without aortic arch calcification."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2013
T58558
UI - Tesis Membership  Universitas Indonesia Library
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Canti Widharisastra
"Hidrosefalus adalah kelainan susunan saraf pusat yang ditandai dengan pelebaran sistem ventrikel. Diperlukan data mengenai ukuran ventrikel serebral normal sebagai batas ambang untuk mendiagnosis pelebaran ventrikel serebral awal. Tujuan penelitian ini untuk mengetahui ukuran ventrikel serebral neonatus aterm normal dan melihat gambaran korelasi parameter pengukuran ventrikel serebral. Penelitian dilakukan terhadap 55 neonatus aterm normal menggunakan modalitas ultrasonografi untuk mendapatkan ukuran ventrikel serebral. Data kuantitatif yang diperoleh dihitung nilai rerata dan digunakan analisis bivariat Pearson/ Spearman untuk melihat gambaran korelasi parameter ukuran ventrikel serebral. Didapatkan rerata ukuran lebar kornu anterior ventrikel lateralis, indeks ventrikel, lebar ventrikel III, jarak talamo-oksipital dan ukuran ventrikel IV. Terdapat korelasi bermakna (p<0,05) antara: lebar kornu anterior kanan dengan indeks ventrikel kanan dengan arah korelasi positif dan kekuatan korelasi sedang (r= 0,506) dan lebar kornu anterior kiri dengan indeks ventrikel kiri dengan arah korelasi positif dan kekuatan korelasi sedang (r=0,488). Tidak terdapat korelasi bermakna (p>0,05) antara : lebar kornu anterior ventrikel lateralis kanan dengan jarak talamo-oksipital kanan dan dari lebar kornu anterior ventrikel lateralis kiri dengan jarak talamo-oksipital kiri. Rerata ukuran ventrikel serebral neonatus aterm normal: lebar kornu anterior ventrikel lateralis 1,50 mm (0,8-3,00 mm); indeks ventrikel 6,52 mm (3,39-12,10 mm); lebar ventrikel III 1,87 mm (0,93-3,80 mm); jarak talamo oksipital 14,82 ±1,69 mm dan ukuran ventrikel IV 4,06 ± 0,53 mm. Ukuran kornu anterior ventrikel lateralis yang besar biasanya disertai indeks ventrikel yang besar pula. Tidak terdapat korelasi antara lebar kornu anterior ventrikel lateralis dengan jarak talamo-oksipital.

Cerebral ventricular dilation is a sign of hydrocephalus. Late diagnosis and late treatment of hydrocephalus can cause parenchymal damage and even death. To diagnose early dilation of cerebral ventricles in neonates required data of the size of the cerebral ventricles as the normal threshold. The purpose of this study was to determine the size of the cerebral ventricles of normal full-term neonates and the correlation parameter ventricular measurement. Study of 55 normal full-term neonates by ultrasonography to establish measurement of parameters ventricular. Quantitative data were obtained calculated mean values and to determinate the correlation parameter cerebral ventricle measurements used bivariate analysis Pearson/ Spearman. Data obtained cerebral ventricular size parameters consisting of the anterior horn width lateral ventricle, ventricular index, the width of the third ventricle, talamo-occipital distance and the size of the fourth ventricle in healthy full-term neonates. There was significant (p <0.05) positive and moderate correlation between: right anterior horn width lateral ventricle with right ventricular index (r = 0.506) as well as left anterior horn width lateral ventricle with left ventricular index (r = 0.488). There were no significant correlation (p> 0.05) between: right anterior horn width lateral ventricle with right talamo-occipital distance and left anterior horn width lateral ventricle with left talamo-occipital distance. The mean size of the cerebral ventricles of healthy full-term neonates are: anterior horn width of the lateral ventricle 1.50 mm(0.8 to 3.00 mm); ventricular index 6.52 mm (3.39 to 12.10 mm); third ventricular width 1.87 mm (0.93 to 3.80 mm); Talamo-occipital distance 14.82 ± 1.69 mm and 4.06 ± fourth ventricle size of 0.53 mm. The greater width of the anterior horn of the lateral ventricle is usually accompanied by greater the ventricular index. There is no correlation between anterior horn width lateral ventricle with the talamo-occipital distance.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
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UI - Tesis Membership  Universitas Indonesia Library
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Annisa Maharani
"Penyakit asma telah dikenal secara luas namum belum pernah dijelaskan secara mendetil. Tomografi komputer resolusi tinggi (HRCT) dapat mendeteksi struktur tidak normal pada penderita asma. Penelitian ini bertujuan untuk mendeskripsikan karakteristik lesi asma dan hubungannya dengan data klinis pada hasil Tes kontrol asma (ACT).
Penelitian dilakukan secara prospektif dengan metode potong lintang terhadap penderita asma yang berobat ke poli asma RSUP Persahabatan Jakarta selama bulan Januari ? Februari 2014, mereka kemudia di rujuk untuk menjalani pemeriksaan HRCT setelah pemeriksaan awal dan mengisi ACT.
Dari 34 kasus, 33 (97%) mengalami penyempitan lumen bronkial, 21 (61,7%) mengalami penebalan dinding bronkial, 15 (44,1%) mengalami gambaran mosaik, 5(5,8%) mengalami bronkiektasis dan seluruhnya (100%) mengalami emfisema. Hasil ACT yang didapat adalah pasien terkontrol sebagian (35,2%) dan tidak terkontrol (64,7%). Ketika dihubungkan dengan hasil ACT, maka penyempitan lumen bronkial (p=0,970), penebalan dinding bronkus (p=0,488), gambaran mosaik (p=0,882), bronkiektasis (p=0,137) dan emfisema tidak menunjukkan hubungan yang signifikan. Lesi lainnya yang ditemukan dan berkaitan dengan ACT adalah tuberkulosis (11,8%; p=0,273), granuloma (2,9%; p=1,000), aspergiloma bronkopulmonari alergik (5,9%; p=0,529) dan bronkitis (5,9%; p=1,000).
Gambaran lesi karakteristik penderita asma bronkial pada HRCT merupakan hal yang penting, karena dapat memperlihatkan komplikasi lain yang menyertai asma, namun karakteristik lesi tersebut tidak berkaitan dengan hasil ACT.

The coexistence of asthma is widely recognized but has not been well described. High resolution computed tomography (HRCT) can detect the structural abnormalities in asthma. This study attempts describe the characteristic lesion of asthma and to correlate these abnormalities with clinical and asthma control test (ACT) data.
We perfomed a prospective cross sectional study of 34 asthma patients who were attending outpatient Persahabatan Hospital, Jakarta from January-February 2014, that were subjected to HRCT after initial evaluation and ACT.
Thirtythree subjects (97%) had narrowing of bronchial lumen, 21 (61.7%) had bronchial wall thickening, 15 (44.1%) had mosaic attenuation, 5 (5.8%) had bronchiectasis and 34 (100%) had emphysema. The ACT result were partial controlled patients (35.2%) and not controlled (64.7%). When correlated with ACT result, the narrowing of bronchial lumen (p=0.970), bronchial wall thickening (p=0.488), mosaic attenuation (p=0.882), bronchiectasis (p=0.137) and emphysema showed no significant association. Another HRCT findings that correlate with ACT were tuberculosis (11.8%; p=0.273), granuloma (2.9%; p=1.000), aspergilloma bronchopulmonary allergica (5.9%; p=0.529) and bronchitis (5.9%; p=1.000).
HRCT findings of characteristic lesion are important in bronchiale asthma patients, because they can describe other complication / comorbidity eventhough they were not correlate well with ACT.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
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UI - Tesis Membership  Universitas Indonesia Library
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Fahriyani
"Latar belakang : penegakkan diagnosis TB paru pada pasien HIV dapat dilakukan berdasarkan pemeriksaan mikrobiologis dan klinis. Rekomendasi WHO 2007, memperbolehkan penegakan diagnosis berdasarkan hasil pemeriksaan klinis dengan dan tanpa melalui pemeriksaan mikrobiologis. Penelitian ini bertujuan mendapatkan perbedaan karakteristik gambaran radiografi toraks pasien HIV dengan TB paru yang didiagnosis berdasarkan pemeriksaan mikrobiologis dan klinis.
Metode : Penelitian ini adalah comparative cross sectional study. Subyek penelitian diambil secara consecutive dan dipilih berdasarkan catatan hasil pemeriksaan BTA sputum, kultur, Genexpert®, CD4+, dan radiografi toraks. Subyek penelitian dikelompokkan menjadi mikrobiologis dan klinis. Dilakukan pembacaan ulang radiografi toraks.
Hasil : gambaran radiografi toraks dengan frekuensi terbanyak pada kelompok diagnosis mikrobiologis adalah infiltrat/konsolidasi, fibroinfiltrat, limfadenopati, kavitas dan kalsifikasi. Sisanya efusi pleura, milier, fibrosis, bronkiektasis, pneumotoraks dan normal. Pada kelompok diagnosis klinis, gambaran radiografi toraks dengan frekuensi terbanyak adalah infiltrat/konsolidasi, kavitas, limfadenopati, fibroinfiltrat dan sisanya kalsifikasi, efusi pleura, milier, fibrosis, bronkiektasis, dan normal. Terdapat perbedaan bermakna karakteristik gambaran radiografi toraks fibroinfiltrat pada kelompok diagnosis mikrobiologis dan klinis. Frekuensi fibroinfiltrat terbanyak adalah di kelompok mikrobiologis dengan sebaran lokasi tersering di lapangan atas paru.
Kesimpulan : Terdapat perbedaan bermakna karakteristik gambaran radiografi toraks fibroinfiltrat pada kelompok diagnosis mikrobiologis dan klinis dengan lokasi tersering di lapangan atas paru.

Background : To diagnose Pulmonary Tuberculosis in HIV patient can be done based on microbiology examination and clinically. WHO 2007 recommendation, allowing diagnosis based on clinical examination with and without microbiological examination. This study aims to obtain the different characteristics of chest radiographs of HIV patients with pulmonary TB were diagnosed based on clinical and microbiological examination.
Methods : This study is a comparative cross-sectional study. Subjects were taken consecutively and selected based on the results of sputum smear examination, culture, Genexpert®, CD4+, and chest x-ray. The study subjects were grouped into microbiological and clinical. Then we do expertise review.
Results : The most chest x-ray finding in the microbiological group is infiltrates/ consolidation. Following by fibroinfiltrat, lymphadenopathy, cavities and calcification. The rest are pleural effusion, miliary, fibrosis, bronchiectasis, pneumothorax and normal . In the group of clinical diagnosis, the highest frequency chest x-ray finding is infiltrates/ consolidation. Following by cavities, lymphadenopathy, fibroinfiltrat and the rest are calcification, pleural effusion, miliary, fibrosis, bronchiectasis and normal. There is significant differences of fibroinfiltrat on microbiological and clinical diagnosis groups. The highest frequency of fibroinfiltrat is in the microbiological group with the most common sites in the upper of the lung field.
Conclusions : There is significant differences of fibroinfiltrat on microbiological and clinical diagnosis groups with the most common sites in the upper lung field.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
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UI - Tesis Membership  Universitas Indonesia Library
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Bahtiar Yahya
"Pendahuluan: Keganasan berhubungan erat dengan keadaan hiperkoagulasi dan berisiko empat kali lipat untuk terjadinya trombosis. Magnetic resonance imaging (MRI) dan magnetic resonance venography (MRV) merupakan metode diagnostik bersifat tidak invasif dan memiliki dengan sensitifitas dan spesifisitas serta akurasi yang tinggi untuk menilai vena serebral dan parenkim otak, three dimensional contrast enhanced (3D-CE) MRV merupakan metode yang mendekati baku emas untuk diagnosis trombosis vena serebral. TVS. Sampai saat ini belum ada penelitian di Indonesia yang membandingkan hasil pemeriksaan MRI serebral rutin dibandingkan dengan pemeriksaan 3D-CE-MRV dalam diagnosis trombosis vena serebra pada penderita keganasan.
Metode: Penelitian diagnostik dengan pendekatan potong lintang menggunakan studi prospektif untuk mengetahui tingkat sensitivitas dan spesifisitas MRI serebral rutin dibandingkan dengan 3D-CE-MRV dalam mendeteksi TVS penderita keganasan.
Hasil: MRI serebral rutin dalam menilai TVS pada penderita keganasan dibandingkan 3D-CE-MRV mempunyai nilai sensitivitas 90%, spesifisitas 50%, nilai duga positif 95% dan nilai duga negatif 75% serta nilai akurasi yang mencapai 95%, sehingga pemeriksaan MRI serebral rutin dapat dijadikan modalitas alternatif untuk diagnosis TVS. Lokasi trombosis yang tersering pada sinus sagitalis superior 63%, kemudian disusul oleh sinus transversus dan sinus rektus sebesar 31,7%, sinus kavernosus 27%, vena kortikal 25%, sinus sigmoid 12,7%, sinus sagitalis inferior 7,9%, sinus confluence 3,2% dan vein of Galen 1,6%. MRI serebral sekuens T1 kontras mempunyai sensitivitas mencapai 94,7% dan nilai spesifisitas 50%, terutama dalam evaluasi sistem vena superfisial, seperti sinus sagitalis superior dan vena kortikal dan terbatas pada sistem vena dalam.
Kesimpulan: MRI serebral rutin dapat dijadikan modalitas alternatif untuk diagnosis TVS.

Introduction: Malignancy closely associated with a hypercoagulable state and four-fold risk for thrombosis. Magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) is a non-invasive diagnostic method and has the sensitivity and specificity as well as high accuracy for assessing cerebral venous and brain parenchyma, three-dimensional contrast enhanced (3D-CE) MRV is a method that approached the gold standard for the diagnosis of cerebral venous thrombosis (CVT). Until now there has been no research in Indonesia, which compared the results of routine cerebral MRI with 3D-CE-MRV in the diagnosis of cerebral venous thrombosis in patients with malignancy.
Methods: The study was cross-sectional diagnostic approach using a prospective study to determine the level of sensitivity and specificity of routine cerebral MRI compared with 3D-CE-MRV in detecting CVT patients with malignancy.
Results: Routine cerebral MRI with contrast in assessing CVT in patients with malignancy compared examination 3D-CE-MRV has a sensitivity value of 90% , specificity value of 50%, positive predictive value of 95% and negative predictive value 75% and as well as the accuracy rate reaches 95%, so the routine examination of cerebral MRI with contrast can be used as an alternative modality for the diagnosis of CVT. Thrombosis location are common in the superior sagittal sinus 63%, followed by the transverse sinus and straight sinus of 31.7%, cavernous sinus 27%, cortical veins 25%, sigmoid sinus 12.7%, inferior sagittal sinus 7.9%, confluence sinus of 3.2% and 1.6% vein of Galen. Cerebral MRI sequences T1 contrast has reached 94.7% sensitivity and specificity values of 50%, especially in the evaluation of the superficial venous system, such as the superior sagittal sinus and cortical veins and limited the deep venous system.
Conclusion: Routine cerebral MRI can be used as an alternative modality for the diagnosis of CVT.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
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UI - Tesis Membership  Universitas Indonesia Library
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Dewi Agus Setyawati
"[ABSTRAK
Tujuan: Studi ini merupakan studi MRI (Magnetic Resonance Imaging) untuk menilai hubungan asimetrisitas volume, hiperintensitas T2WI FLAIR dan nilai ADC hippokampus hubungannya dengan lateralisasi kejang. Pemeriksaan MRI sekuens rutin ditambah prosedur khusus pemeriksaan hipokampus yaitu sekuens T2WI Inversion Recovery dan T2WI Fluid-attenuated inversion recovery (FLAIR) dapat menilai volume hipokampus. Sekuens DWI (Diffusion Weighted Image) dan ADC (Appearent Difusion Coeffesient) merupakan pemeriksaan kuantitatif.
Metode: Penelitian potong lintang menggunakan data sekunder MRI kepala pasien dengan diagnosis epilepsi lobus temporal mesial. Dilakukan pengukuran volume pada potongan koronal sejajar sumbu hippokampus, mulai dari terlihat kepala hippokampus sebanyak 5 irisan. Melihat gambaran hiperintensitas T2WI FLAIR serta mengukur nilai ADC hippokampus dilakukan dengan meletakan ROI pada potongan aksial hippokampus terbesar pada ADC map. Analisis data dilakukan untuk menghitung nilai R Kappa hubungan masing masing variabel dan gabungan variabel.
Hasil: Jumlah subyek penelitian 54 orang, terdapat hubungan asosiasi yang cukup kuat (sedang) dan ipsilateral antara hiperintensitas T2WI FLAIR dan asimetrisitas volume dengan lateralisasi kejang dengan R Kappa sama sebesar + 0.52. Hubungan asosiasi yang lemah dan bersifat ipsi lateral dengan R Kappa + 0.37 antara nilai ADC dengan lateralisasi kejang. Hubungan asosiasi antara asimetrisitas volume dan asimetrisitas nilai ADC adalah kontralateral dengan hubungan asosiasi cukup kuat (sedang). Penentuan lateralisasi lesi dengan MRI pada masing masing variabel memiliki sensitivitas dan spesifisitas cukup tinggi. Hubungan asosiasi gabungan 2 dan 3 variabel adalah cukup kuat (sedang) dan bersifat ipsilateral, dengan nilai R Kappa, sensitifitas dan spesifisitanya yang lebih tinggi dibandingkan dengan hubungan masing masing variabel.
Kesimpulan: MRI memiliki peranan penting menentukan lateralisasi kejang. Menilai hubungan dari gabungan 2 dan 3 variabel didapatkan secara statistik lebih besar hubungannya dengan lateralisasi kejang dibandingkan dengan menghubungkan masing masing variabel secara terpisah, sehingga penilaian MRI yang dilakukan untuk ke 3 variabel ini akan lebih menguatkan diagnosis sisi hipokampus yang mengalami kelainan.

ABSTRACT
Objective: This study is MRI ( Magnetic Resonance Imaging ) to assess the relationship asymmetry volume, T2WI FLAIR hyperintensity and hippocampal ADC values its relationship with the lateralization of seizures. Routine MRI examination sequences plus a special procedure that hippocampal examination Inversion Recovery sequence T2WI and T2WI Fluid-attenuated inversion recovery ( FLAIR ) can assess hippocampal volume. Sequences DWI ( Diffusion Weighted Image ) and ADC ( Appearent Diffusion Coeffesient ) is a quantitative examination.
Methods: A cross-sectional study using secondary data MRI diagnosis of the patient's head with mesial temporal lobe epilepsy. Volume measurements performed on coronal slice axis parallel to the hippocampus, ranging from the visible head of the hippocampus as much as 5 slices. See picture T2WI FLAIR hyperintensity and measuring the ADC value hippocampus done by placing the ROI on axial cuts at the largest hippocampal ADC map. Data analysis was performed to calculate the value of R Kappa relationship each and combined variable.
Results: There is a fairly strong association relationship (medium) and ipsilateral between T2WI FLAIR hyperintensity volume and asymmetry with lateralization of seizures with R Kappa equal to + 0.52. A weak association relationship and are IPSI lateral with R Kappa + 0.37 between the ADC values with lateralization of seizures. Association relationship between volume and asymmetry value asymmetry ADC is contralateral to the association relationship is strong enough (medium). Determination of lateralization of lesions by MRI in each variable has a fairly high sensitivity and specificity. The combined association relationship 2 and 3 variables are strong enough (medium) and ipsilateral, with a value of R Kappa, sensitivity and spesifisitanya higher than the correlation of each variable.
Conclusion: MRI has an important role determining the lateralization of seizures. Assess the relationship of the combined second and third variables are statistically bigger obtained conjunction with lateralization of seizures compared to connecting each variable separately, so the MRI assessment carried out for 3 to this variable will further strengthen the diagnosis of hippocampal abnormalities., Objective: This study is MRI ( Magnetic Resonance Imaging ) to assess the relationship asymmetry volume, T2WI FLAIR hyperintensity and hippocampal ADC values its relationship with the lateralization of seizures. Routine MRI examination sequences plus a special procedure that hippocampal examination Inversion Recovery sequence T2WI and T2WI Fluid-attenuated inversion recovery ( FLAIR ) can assess hippocampal volume. Sequences DWI ( Diffusion Weighted Image ) and ADC ( Appearent Diffusion Coeffesient ) is a quantitative examination.
Methods: A cross-sectional study using secondary data MRI diagnosis of the patient's head with mesial temporal lobe epilepsy. Volume measurements performed on coronal slice axis parallel to the hippocampus, ranging from the visible head of the hippocampus as much as 5 slices. See picture T2WI FLAIR hyperintensity and measuring the ADC value hippocampus done by placing the ROI on axial cuts at the largest hippocampal ADC map. Data analysis was performed to calculate the value of R Kappa relationship each and combined variable.
Results: There is a fairly strong association relationship (medium) and ipsilateral between T2WI FLAIR hyperintensity volume and asymmetry with lateralization of seizures with R Kappa equal to + 0.52. A weak association relationship and are IPSI lateral with R Kappa + 0.37 between the ADC values with lateralization of seizures. Association relationship between volume and asymmetry value asymmetry ADC is contralateral to the association relationship is strong enough (medium). Determination of lateralization of lesions by MRI in each variable has a fairly high sensitivity and specificity. The combined association relationship 2 and 3 variables are strong enough (medium) and ipsilateral, with a value of R Kappa, sensitivity and spesifisitanya higher than the correlation of each variable.
Conclusion: MRI has an important role determining the lateralization of seizures. Assess the relationship of the combined second and third variables are statistically bigger obtained conjunction with lateralization of seizures compared to connecting each variable separately, so the MRI assessment carried out for 3 to this variable will further strengthen the diagnosis of hippocampal abnormalities.]"
2015
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UI - Tesis Membership  Universitas Indonesia Library
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Rio Kusuma
"Latar belakang dan tujuan: Mikrotia adalah malformasi kongenital yang seringkali disertai atresia auris dan kelainan telinga tengah. Kelainan ini dikoreksi dengan kanaloplasti dan timpanoplasti. Titik dan arah pengeboran kanaloplasti merupakan hal yang penting. Saat ini belum terdapat panduan yang objektif dalam menentukan arah pengeboran. Volume telinga tengah, berperan penting dalam penentuan keluaran hasil pembedahan, namun saat ini belum pernah dikaitkan dengan sudut α dan β. Penelitian ini bertujuan menilai hubungan sudut α dan β dengan volume telinga tengah tmikrotia dan telinga normal menggunakan HRCT temporal.
Metode: Menggunakan desain potong lintang. Subjek penelitian merupakan data sekunder HRCT tulang temporal, kemudian dilakukan pengukuran sudut α dan β dan volume telinga tengah.
Hasil: Subjek penelitian berjumlah 34 sampel. Terdapat perbedaan bermakna sudut α dan sudut β telinga mikrotia dibandingkan telinga normal, dengan nilai p<0.001. Rerata volume telinga tengah mikrotia 0.36 cc, normal 0.67 cc. Tidak didapatkan korelasi volume telinga tengah dengan sudut α dan β, pada mikrotia maupun telinga normal. Nilai cut-off sudut α sebesar 15.40, sensitivitas 85.3% dan spesifisitas 82.4%. nilai cut-off sudut β sebesar 270, sensitivitas 73.5% dan spesifisitas 76.5%.
Kesimpulan: Perbedaan posisi osikular dengan nilai cut-off yang didapat untuk sudut α dan β dapat menjadi acuan dasar pada operasi kanaloplasti.

Background and Objectives: Microtia is a congenital malformation with associated auricle atresia and middle ear abnormality, which is treated by canaloplasty and tympanoplasty. Drilling starting point and the direction in canaloplasty operation are no doubt very important things. Nowadays, guideline for determining the drilling direction has not been yet established. Middle ear volume which is one of important variable in determining operation outcome, has not been associated with α and β angle. This study intended to evaluate α and β angle and its relationship with middle ear volume using (HRCT) temporal bone.
Method: Cross-sectional design were used. Data from previous HRCT examination were used to measured α and β angle and middle ear volume.
Results: From 34 subjects, there were significant differences of α and β angle in microtic ear compared to normal ear, with p < 0.001. Middle ear volume average for microtic ear and normal ear were 0.36 cc and 0.67 cc, respectively. No significant correlation between middle ear volume and α and β angle. Cut-off value for α angle is 15.40 with sensitivity 85.3% and specificity 82.4%. Cut-off value for β angle is 270 with sensitivity 73.5% and specificity 76.5%.
Conclusion: Differences in ossicular position with obtained cut-off value for α and β angle could become a base guidance in canaloplasty operation.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tesis Membership  Universitas Indonesia Library
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Ira Rahma Hidayati
"[ABSTRAK
Latar belakang: Penggunaan media kontras pada pemeriksaan radiologi dengan kondisi pasien mengalami insufisiensi fungsi ginjal dapat menyebabkan resiko terjadinya CIN pada kontras iodine dan NSF pada kontras paramagnetik. Oleh karena itu, penilaian fungsi ginjal penting dilakukan sebelum pemeriksaan radiologi kontras. Permasalahannya untuk menilai fungsi ginjal dengan baku emas sulit dilakukan sehingga digunakan formula MDRD dan CKD-EPI untuk menghitung eGFR. Faktor ras menjadi salah satu variabel dalam formula penghitungan eGFR, belum ada untuk populasi Indonesia yang termasuk ras Melanesia dan Malayan-Mongoloid. Tujuan: Menilai apakah terdapat korelasi antara pengukuran eGFR metode MDRD dan CKD-EPI dengan pengukuran GFR 99mTc-DTPA metode Gates pada pasien CKD. Metode: Penelitian potong lintang menggunakan data sekunder pasien yang menjalani pemeriksaan skintigrafi renal di RSUPN Cipto Mangunkusumo serta pemeriksaan kreatinin serum bulan Februari 2012-Januari 2015. Data kasar dinilai ulang GFR skintigrafi renal menggunakan metode Gates dari pesawat Siemens Symbia T2 dan dihitung nilai eGFR menggunakan formula MDRD dan CKD-EPI. Analisa data dilakukan untuk mendapatkan nilai korelasi eGFR formula MDRD dan CKD-EPI dengan GFR skintigrafi renal sebagai baku emas. Hasil: Jumlah subjek penelitian 47 orang, dengan hasil terdapat korelasi positif, kekuatan korelasi baik antara nilai eGFR MDRD dengan GFR skintigrafi renal dengan persamaan:nilai GFR skintigrafi renal=16,60+0,70xnilai eGFR MDRD. Terdapat korelasi positif, kekuatan korelasi baik antara nilai eGFR CKD-EPI dengan GFR skintigrafi renal dengan persamaan:nilai GFR skintigrafi renal=12,74+0,78xnilai eGFR CKD-EPI; nilai GFR dalam ml/menit/1,73m2. Kesimpulan : Formula persamaan eGFR MDRD dan CKD-EPI dapat digunakan dalam klinis untuk memperkirakan nilai GFR skintigrafi renal.

ABSTRACT
Background: The use of contrast media for radiology examination in patients with renal function insufficiency can lead to the risk of CIN (Contrast Induced Nephropathy) on contrast iodine and NSF (Nephrogenic Systemic Fibrosis) on paramagnetic contrast. Therefore, assessment of renal function is important to be done prior to contrast radiology. The problem is assessing renal function with a gold standard, clinically difficult, therefor using MDRD and CKD-EPI formula to calculate eGFR. Factors race became one of the variables in the formula calculating eGFR, yet for Indonesian population included in the Melanesian and Malayan-Mongoloid race.Objective. To evaluate correlation value between eGFR measurement using MDRD and CKD-EPI methods with GFR Gates methods using 99mTc-DTPA in patients with CKD.Method: Cross sectional research using secondary data of patients who underwent renal scintigraphy in Cipto Mangunkusumo and serum creatinine examination in February 2012 to January 2015. The raw data then reassessed GFR renal scintigraphy using the Gates of Siemens Symbia T2 machine and eGFR values calculated using the formula MDRD and CKD-EPI. Data analysis was used to obtain a correlation value formula MDRD eGFR and CKD-EPI with GFR renal scintigraphy as the gold standard. Result: Total subject is 47 people. There is a positive correlation with good correlation value between MDRD eGFR value and renal scintigraphy GFR using this approach:renal scintigraphy GFR value=16,60+0,70xMDRD eGFR value. There is also a positive correlation with good correlation value between MDRD eGFR value and renal scintigraphy GFR value using this approach:renal scintigraphy GFR value=12,74+0,78xCKD=EPI eGFR value. Conclusion : Formula equation MDRD and CKD-EPI eGFR can be used clinically to estimate renal scintigraphy GFR, Background: The use of contrast media for radiology examination in patients with renal function insufficiency can lead to the risk of CIN (Contrast Induced Nephropathy) on contrast iodine and NSF (Nephrogenic Systemic Fibrosis) on paramagnetic contrast. Therefore, assessment of renal function is important to be done prior to contrast radiology. The problem is assessing renal function with a gold standard, clinically difficult, therefor using MDRD and CKD-EPI formula to calculate eGFR. Factors race became one of the variables in the formula calculating eGFR, yet for Indonesian population included in the Melanesian and Malayan-Mongoloid race.Objective. To evaluate correlation value between eGFR measurement using MDRD and CKD-EPI methods with GFR Gates methods using 99mTc-DTPA in patients with CKD.Method: Cross sectional research using secondary data of patients who underwent renal scintigraphy in Cipto Mangunkusumo and serum creatinine examination in February 2012 to January 2015. The raw data then reassessed GFR renal scintigraphy using the Gates of Siemens Symbia T2 machine and eGFR values calculated using the formula MDRD and CKD-EPI. Data analysis was used to obtain a correlation value formula MDRD eGFR and CKD-EPI with GFR renal scintigraphy as the gold standard. Result: Total subject is 47 people. There is a positive correlation with good correlation value between MDRD eGFR value and renal scintigraphy GFR using this approach:renal scintigraphy GFR value=16,60+0,70xMDRD eGFR value. There is also a positive correlation with good correlation value between MDRD eGFR value and renal scintigraphy GFR value using this approach:renal scintigraphy GFR value=12,74+0,78xCKD=EPI eGFR value. Conclusion : Formula equation MDRD and CKD-EPI eGFR can be used clinically to estimate renal scintigraphy GFR]"
Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tugas Akhir  Universitas Indonesia Library
cover
Rommy Zunera
"[ABSTRAK
Latar Belakang : pengukuran VPW dari modalitas foto toraks merupakan
pemeriksaan yang non invasif, cepat dan mudah untuk memprediksi kondisi
hipervolemia. Namun belum terdapat konsensus nilai rerata VPW yang dipakai
secara global, sehingga penggunaan nilai rerata VPW dari penelitian sebelumnya
terhadap populasi diluar populasi penelitian tersebut mungkin tidak relavan. Di
Indonesia khususnya di Rumah Sakit Cipto Mangunkusumo belum terdapat data
dasar nilai rerata VPW.
Tujuan Penelitian: Mengetahui rerata nilai VPW dewasa normal Indonesia
Desain Penelitian: Retrospektif potong lintang
Metode: Pengukuran jarak antara tepi terluar arteri subklavia kiri dengan tepi
terluar vena kava superior yang melewati bronkus utama kanan (VPW),
pengukuran rasio VPW terhadap diameter jantung terluas dan rasio VPW terhadap
diameter terluas rongga toraks. Pengukuran dilakukan pada radiografi toraks PA
dari 104 subyek normal yang terdiri dari 52 laki-laki dan 52 perempuan, dihitung
rerata dan standar deviasi. Pengukuran serupa juga dilakukan pada topogram CT
scan toraks (radiografi toraks AP supine) dan CT scan toraks dari 103 subyek
yang terdiri dari 51 laki-laki dan 52 perempuan.
Hasil: Pada pemeriksaan toraks PA didapatkan rerata VPW 48,0 mm ± 5,5 mm,
rerata VPCR 40,3% ± 4,6 %, dan rerata VPTR 17,2% ± 1,7%. Pada pemeriksaan
topogram CT scan didapatkan rerata VPW 50,3 mm ± 6,2 mm, rerata VPTR 45%
± 5,1%, dan rerata VPTR 19,8% ± 2,5%. Rerata VPW pada CT scan toraks 50,4 ±
6,1 mm. Pengukuran pada foto toraks AP sekitar 10 % lebih besar dibandingkan
pada foto toraks PA, dan pengukuranVPW pada foto toraks terbukti memiliki
akurasi yang tinggi.
Kesimpulan: Rerata VPW pada pemeriksaan foto toraks PA tegak dewasa normal
Indonesia adalah 48 ± 5,5 mm, ternyata tidak berbeda bermakna dengan rerata
VPW pada populasi barat ( 48 ± 5mm). Rerata VPCR pada foto toraks PA
adalah 40,3 % ± 4,6 % dan VPTR adalah 17,2 % ± 1,7 %.

ABSTRACT
Background: Vascular pedicle width (VPW) is the distance, from a perpendicular
line at the takeoff point of the left subclavian artery off the aorta to the point at
which the superior vena cava. Measurement of VPW on chest x-ray is relatively
non-invasive, fast and easy technique as hypervolemia predictor, but no
wordwide consensus has been proposed.
Objective: to investigate mean vascular pedicle witdh of Indonesian adult
Study design: Retrospective cross sectional
Methods : VPW is the distance, measure in millimeters, from a perpendicular line
at the takeoff point of the left subclavian artery to the point at which the superior
vena cava crosses the right main bronchus, than calculate VPW ratio to a widest
horizontal diameter of cardiac dan thoracic wall.
Results : Data from 104 PA chest x-ray of normal subjects and 103 thoracic CT
scan of selected subjects. On PA chest x-ray obtained mean VPW 48,0 mm ± 5.5
mm, mean VPCR 40.3% ± 4.6%, and mean VPTR 17.2% ± 1.7%. On CT scan
topogram obtained mean VPW 50,3 mm ± 6.2 mm, mean VPTR 45% ± 5.1%, and
mean VPTR 19.8% ± 2.5%. On thoracic CT scan obtained mean VPW 50.4 ± 6.1
mm. Measurements on the AP chest x-ray about 10% greater than in the PA
chest x-ray, and measurement of VPW on conventional chest x-ray aproved to
have high accuracy.
Conclusions :The mean VPW on erect chest x-ray of Indonesian adult is 48 ± 5,5
mm, no significant different between westerns population ( 48 ± 5mm).;Background: Vascular pedicle width (VPW) is the distance, from a perpendicular
line at the takeoff point of the left subclavian artery off the aorta to the point at
which the superior vena cava. Measurement of VPW on chest x-ray is relatively
non-invasive, fast and easy technique as hypervolemia predictor, but no
wordwide consensus has been proposed.
Objective: to investigate mean vascular pedicle witdh of Indonesian adult
Study design: Retrospective cross sectional
Methods : VPW is the distance, measure in millimeters, from a perpendicular line
at the takeoff point of the left subclavian artery to the point at which the superior
vena cava crosses the right main bronchus, than calculate VPW ratio to a widest
horizontal diameter of cardiac dan thoracic wall.
Results : Data from 104 PA chest x-ray of normal subjects and 103 thoracic CT
scan of selected subjects. On PA chest x-ray obtained mean VPW 48,0 mm ± 5.5
mm, mean VPCR 40.3% ± 4.6%, and mean VPTR 17.2% ± 1.7%. On CT scan
topogram obtained mean VPW 50,3 mm ± 6.2 mm, mean VPTR 45% ± 5.1%, and
mean VPTR 19.8% ± 2.5%. On thoracic CT scan obtained mean VPW 50.4 ± 6.1
mm. Measurements on the AP chest x-ray about 10% greater than in the PA
chest x-ray, and measurement of VPW on conventional chest x-ray aproved to
have high accuracy.
Conclusions :The mean VPW on erect chest x-ray of Indonesian adult is 48 ± 5,5
mm, no significant different between westerns population ( 48 ± 5mm).;Background: Vascular pedicle width (VPW) is the distance, from a perpendicular
line at the takeoff point of the left subclavian artery off the aorta to the point at
which the superior vena cava. Measurement of VPW on chest x-ray is relatively
non-invasive, fast and easy technique as hypervolemia predictor, but no
wordwide consensus has been proposed.
Objective: to investigate mean vascular pedicle witdh of Indonesian adult
Study design: Retrospective cross sectional
Methods : VPW is the distance, measure in millimeters, from a perpendicular line
at the takeoff point of the left subclavian artery to the point at which the superior
vena cava crosses the right main bronchus, than calculate VPW ratio to a widest
horizontal diameter of cardiac dan thoracic wall.
Results : Data from 104 PA chest x-ray of normal subjects and 103 thoracic CT
scan of selected subjects. On PA chest x-ray obtained mean VPW 48,0 mm ± 5.5
mm, mean VPCR 40.3% ± 4.6%, and mean VPTR 17.2% ± 1.7%. On CT scan
topogram obtained mean VPW 50,3 mm ± 6.2 mm, mean VPTR 45% ± 5.1%, and
mean VPTR 19.8% ± 2.5%. On thoracic CT scan obtained mean VPW 50.4 ± 6.1
mm. Measurements on the AP chest x-ray about 10% greater than in the PA
chest x-ray, and measurement of VPW on conventional chest x-ray aproved to
have high accuracy.
Conclusions :The mean VPW on erect chest x-ray of Indonesian adult is 48 ± 5,5
mm, no significant different between westerns population ( 48 ± 5mm)., Background: Vascular pedicle width (VPW) is the distance, from a perpendicular
line at the takeoff point of the left subclavian artery off the aorta to the point at
which the superior vena cava. Measurement of VPW on chest x-ray is relatively
non-invasive, fast and easy technique as hypervolemia predictor, but no
wordwide consensus has been proposed.
Objective: to investigate mean vascular pedicle witdh of Indonesian adult
Study design: Retrospective cross sectional
Methods : VPW is the distance, measure in millimeters, from a perpendicular line
at the takeoff point of the left subclavian artery to the point at which the superior
vena cava crosses the right main bronchus, than calculate VPW ratio to a widest
horizontal diameter of cardiac dan thoracic wall.
Results : Data from 104 PA chest x-ray of normal subjects and 103 thoracic CT
scan of selected subjects. On PA chest x-ray obtained mean VPW 48,0 mm ± 5.5
mm, mean VPCR 40.3% ± 4.6%, and mean VPTR 17.2% ± 1.7%. On CT scan
topogram obtained mean VPW 50,3 mm ± 6.2 mm, mean VPTR 45% ± 5.1%, and
mean VPTR 19.8% ± 2.5%. On thoracic CT scan obtained mean VPW 50.4 ± 6.1
mm. Measurements on the AP chest x-ray about 10% greater than in the PA
chest x-ray, and measurement of VPW on conventional chest x-ray aproved to
have high accuracy.
Conclusions :The mean VPW on erect chest x-ray of Indonesian adult is 48 ± 5,5
mm, no significant different between westerns population ( 48 ± 5mm).]"
2015
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UI - Tesis Membership  Universitas Indonesia Library
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