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Abstrak :
Latar belakang: Pilot dapat mengalami obes yang berkaitan dengan jam terbang total atau faktor risiko lainnya. Oleh karena itu, perlu diidentifikasi kaitan jam terbang total dan faktor lainnya terhadap risiko obes pada pilot sipil di Indonesia. Metode: Studi ini memakai metode potong lintang dengan sampel purposif pada pilot yang melakukan pemeriksaan kesehatan berkala di Balai Kesehatan Penerbangan tanggal 14-24 Mei 2013. Data yang dikumpulkan yaitu karakteristik demografi, pekerjaan, kebiasaan makan dan olahraga, tinggi dan berat badan serta lingkar pinggang. Pengambilan data dilakukan dengan wawancara dan pemeriksaan fisik. Analisis menggunakan regresi Cox dengan waktu yang konstan. Subjek dikategorikan menjadi obes (indeks massa tubuh (IMT) 25 atau lebih untuk ras Asia, dan 30 atau lebih untuk ras Kaukasia), dan normal (IMT 18.5-22.9) Hasil: Di antara 612 pilot yang berusia 18-61 tahun, diperoleh 133 subjek obes dan 41 subjek normal. Faktor-faktor dominan yang berkaitan dengan obes adalah jam terbang total dan lingkar pinggang. Faktor kebiasaan makan makanan berlemak dan cepat saji tidak terbukti mempertinggi risiko obes. Dibandingkan subjek dengan lingkar pinggang normal, subjek dengan lingkar pinggang besar memiliki kemungkinan 77% lebih tinggi untuk obes [risiko relatif suaian (RRa) = 1,77; 95% interval kepercayaan (CI) =1,41-2,14]. Dibandingkan subjek dengan jam terbang kurang dari sama dengan 1000 jam, subjek dengan jam terbang total lebih dari 1000 jam memiliki risiko obes 33% lebih tinggi (RRa = 1,77; 95% CI = 1,11-1,59) Kesimpulan: Jam terbang total 1001-29831 dan lingkar pinggang besar mempertinggi risiko obes di antara pilot sipil di Indonesia. ......Background: Pilot may obese which is related to total flight hours and other risk factors. This study aimed to identify the relationship between total flight hours and other factors related to obese in civil pilots in Indonesia. Methods: A cross-sectional study with purposive sampling among pilot undergoing periodic medical check up in 14-24 Mei at Aviation Medical Center (Balai Kesehatan Penerbangan). Data collected were demographic and work characteristics, eating habit, exercise habit, height, weight and waist circumference, high fat diet and fast food consumption were not found to increase the risk of obese. Subject were classified into obese (Body Mass Index = BMI) was 25 or more for Asians and 30 or more for Caucasian) and normal (BMI 18.5-22.9). Results: A number of 612 pilots, aged 18-61 years old, 133 available for this study which consisted of 133 obese pilots and 41 normal body weight. Subjects with large waist circumference than normal waist circumference had 77% increased risk of obese [relative risk adjusted (RRa) = 1.77; 95% confidence interval (CI) = 1.41-2.14]. Total flight hours 1001 or more, than less 1000 hours had 33% increased risk to be obese (RRa = 1.33; 95% CI =1.11-1.59). Conclusions: Total flight hours of 1001-29831 hours and large waist circumference increased the risk of obese in civil pilots in Indonesia.

Abstrak :
Latar Belakang: Obesitas dapat menganggu kesehatan dan mempengaruhi penerbang dalam menjalankan tugasnya. Tujuan penelitian ini untuk mengidentifikasi faktor-faktor yang berhubungan dengan risiko obesitas pada penerbang sipil di Indonesia. Metode: Studi potong lintang dengan sampel purposif pada penerbang sipil yang sedang melakukan pemeriksaan kesehatan berkala di Balai Kesehatan Penerbangan pada tanggal 18-29 Mei 2015. Data yang dikumpulkan meliputi faktor demografi, pekerjaan, sosial, genetik, pengetahuan, sikap dan perilaku. Data dikumpulkan dengan wawancara dan pengukuran antropometri. Analisis menggunakan regresi Cox dengan waktu konstan. Hasil: Dari 690 penerbang, 428 subjek bersedia menjadi responden. Subjek terpilih untuk dianalisis berjumlah 259 penerbang terdiri dari 184 obesitas dan 75 subjek dengan berat badan normal. Dibandingkan subjek dengan kebiasaan hampir tidak pernah makan makanan berlemak, subjek dengan kebiasaan makan makanan berlemak 3-4 kali per minggu berisiko obesitas 6,3 kali lipat [risiko relatif suaian (RRa)=6,28; 95% interval kepercayaan (CI)=1,55-25,46; p=0,010], sedangkan pada subjek dengan kebiasaan makan makanan berlemak hampir setiap hari berisiko obesitas 6 kali lipat (RRa=6,04; CI=1,43-25,54; p=0,014). Selanjutnya, jika dibandingkan dengan subjek yang memiliki 16-1499 jam terbang total, subjek yang memiliki 1500-4999 jam terbang total berisiko 18% lebih tinggi obesitas (RRa=1,18; 95% CI=1,01-1,39; p=0,038) dan subjek yang memiliki 5000-28000 jam terbang total berisiko 39% lebih tinggi obesitas (RRa=1,39; 95% CI=0,99-1,93; p=0,052). Simpulan: Kebiasaan makan makanan berlemak 3 kali atau lebih per minggu dan jam terbang total 1500 jam atau lebih meningkatkan risiko obesitas pada penerbang sipil di Indonesia. ...... Background: Obesity can interfere and affect the health of pilots in performing their duties. The purpose of this study was to identify factors associated with the risk of obesity among civilian pilots in Indonesia. Methods: Cross-sectional study was done with purposive sampling among civilian pilots undergoing periodic medical examinations at Civil Aviation Medical Center on May 18-29th, 2015. Data collected were demographic, occupation, social, genetic, knowledge, attitudes and behavior factors. Data were collected through interviews and anthropometric measurements. Data analysis used Cox regression with constant time. Results: There were 690 pilots eligible for this study, 428 subjects were willing to become respondents. The subject chosen for analysis amounted to 259 pilots, with 184 pilots were obese and 75 had normal BMI. Compared with pilots who rarely consumed fatty foods, pilots who ate fatty foods 3-4 times/week had 6.3-fold risk of obesity [adjusted relative risk (RRa)=6.28; 95% confidence interval (CI)=1.55-25.46; p=0.010], whereas the pilots who ate fatty foods almost everyday had 6-fold risk of obesity (RRa=6.04; CI=1.43-25.54; p=0.014). Furthermore, when compared to pilots with 16-1499 total flight hours, pilots with 1500-4999 total flight hours had 18% higher risk of obesity (RRa=1.18; 95% CI=1.01-1.39; p=0.038) and pilots with 5000-28000 total flight hours had 39% higher risk of obesity (RRa=1.39; 95% CI=0.99-1.93; p=0.052). Conclusions: Eating fatty foods habit 3 times/week or more and 1500 or more of total flight hours increased the risk of obesity among civilian pilots in Indonesia.

Abstrak :
ABSTRAK
Penelitian ini merupakan uji validitas dan reliabilitas kuesioner Morisky Medication Adherence Scale 8 (MMAS-8) versi bahasa Indonesia untuk mengukur kepatuhan konsumsi statin pada 40 penerbang militer di Skadron Udara Halim Perdanakusuma pada tanggal 6 April-15 Mei 2016. Hiperkolesterolemia merupakan penyebab penyakit kardiovaskular yang dapat menyebabkan inkapasitasi dalam penerbangan. Salah satu cara untuk mengontrol hiperkolesterolemia adalah dengan minum obat antikolesterol golongan statin, namun belum ada instrumen yang dapat digunakan untuk mengukur kepatuhan minum obat statin di kalangan penerbang militer di Indonesia. Validitas diuji dengan validitas kriteria. Reliabilitas diuji dengan konsistensi internal dan uji ulang (test-retest). Didapatkan korelasi negatif lemah dan tidak ditemukan hubungan bermakna antara antara kadar kolesterol dan tingkat kepatuhan minum statin (koefisien Spearman -0,199; p=0,218). Konsistensi internal moderat (Cronbach?s α=0,759) dengan reliabilitas tes ulang yang baik (koefisien Spearman=0,860). Hasil uji validitas dan reliabilitas MMAS 8 versi bahasa Indonesia pada penerbang militer belum dapat digunakan untuk mengukur kepatuhan minum statin pada penerbang militer di Indonesia.

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ABSTRACT
This study analyzed the validity and reliability of Morisky Medication Adherence Scale 8 (MMAS-8) Bahasa version to measure statin adherence among 40 military pilots in Halim Perdanakusuma Air Force Base on April 06th-May 15th 2016. Hypercholesterolemia is the cause of cardiovascular disease which lead to inflight incapacitation. One of the way to control hypercholesterolemia is using statin medication, however there has not been an instrument to measure statin adherence in military pilots in Indonesia. Validity was confirmed using crirerion-related validity. Reliability was tested for internal consistency and test-retest reliability. Negative weak correlation and no significant association between cholesterol and statin adherence level (Spearman coefficient -.199, p=0.218) was found. Moderate internal consistency and excellent test-retest reliability were found (Cronbach?s α=0.759; Spearman correlation=0.860). Validity and reliability of MMAS 8 Bahasa version has not been able to be used to measure statin adherence among military pilots in Indonesia.

Abstrak :
Tujuan penelitian adalah diketahuinya pengaruh pemberian suplementasi makanan cair 500 kalori per hari berturut-turut dari awal radiasi sampai radiasi ke 20 terhadap kadar albumin serum dan berat badan pasien kanker nasofaring yang menjalani kemoradioterapi. Penelitian ini merupakan uji klinis paralel, membandingkan kelompok yang mendapat suplementasi makanan cair disertai penyuluhan gizi dan diet sehari-hari (P) dengan kelompok yang hanya mendapat penyuluhan gizi dan diet sehari-hari saja (K). Sebanyak 18 pasien kanker nasofaring yang menjalani kemoradioterapi yang memenuhi kriteria dibagi dalam dua kelompok secara randomisasi blok. Data yang diambil meliputi usia, jenis kelamin, indeks massa tubuh, stadium penyakit, asupan energi dan protein dengan food recall 1 x 24 jam Serta kebutuhan energi dan protein dengan rumus Harris- Benedict. Pemeriksaan kadar albumin semm Serta berat badan dilalcukan pada awal dan akhir perlakuan. Analisis data menggunakan uji t tidak berpasangan dan berpasangan Serta uji Mann Whitney dengan batas kemaknaan 5%. Diperoleh 8 orang di kelompok P dan 8 orang di kelompok K dengan usia 18-59 tahun yang mengikuti penelitian secara lengkap. Tidak ada perbedaan data awal yang bermakna antara kelompok P dan kelompok K. Pcnurunan ltadar albumin serum pada kelompok P Iebih rendah daripada kelompok K. Diperoleh rerata persentase penurunan berat badan pada kelompok P yang kurang 2,24 % dari kelompok K, namun secara statistik tidak bermakna. Pemberian suplementasi makanan cair 500 kalori per hari berturut-turut dari awal radiasi sampai radiasi ke 20 tidak dapat mempertahankan kadar albumin serum dan mengurangi rerata persentase penurunan berat badan pada kelompok perlakuan. ......The aims of this study were to investigate the influence of 500 calorie per day liquid food supplementation from the first day of chemoradiotherapy until twenty times radiation therapy on serum albumin level and body weight in nasopharynx cancer patients undergoing chemoradiotherapy. The study was a parallel randomized clinical trial.` Eighteen subjects of nasopharynx cancer patients treated with a targeted chemoradiotherapy were selected using certain criteria. The randomly (block randomization) eighteen subject were divided into two group. The treatment group received 500 calorie per day liquid food supplementation from the first day of treatment until twenty times radiation therapy, nutrition counseling and daily diet; the control group received nutrition counseling and daily diet alone. This study was conducted at Dr. Cipto Mangunkusumo Hospital Department of Radiotherapy. Data collected included age, gender, body weight and tall, body mass index, intake of energy and protein, and using l x 24 hours food recall. Laboratory 'findings (serum albumin levels) were done before and after intervention. For statistical analysis, impaired t-test, paired t-test and Mann Whitney were used with the level of significance was 5%. Eight subjects in the treatment group and Eight subjects in the control group completed the study and analyzed. The characteristic data of the two groups at baseline were not significantly different, therefore they were closely matched at baseline. There were decrease of serum albumin in both group, but it was lower in the treatment group than the control group, although it is not statistically significant (p>0,05). There were a 23,24 % relative reduction in weight loss in the treatment group but it is not statistically significant. In conclusions, the influence of 500 calorie per day liquid -food supplementation from the first day of chemo radiotherapy until twenty times radiation' did not preserve serum albumin level and were not reduction in weight loss in the treatment group.

Abstrak :
Infeksi HIV menghasilkan radikal bebas yang merusak sel dan berbagai organ tubuh. Antioksidan berperan penting untuk mengatasi kerusakan akibat radikal bebas. Penelitian dengan desain potong lintang ini merupakan bagian dari penelitian bersama untuk mengetahui korelasi kadar antioksidan (beta karoten, vitamin C, E dan seng) dengan kadar SOD pada penderita HIV/AIDS di Pokdisus AIDS FKUI/RSUPNCM, Jakarta. Pengumpulan data dilakukan sejak akhir bulan Februari 2013 sampai Maret 2013 dengan metode consecutive sampling, didapatkan 52 orang subyek memenuhi kriteria penelitian. Hasil penelitian menunjukkan median usia subyek 33 (24-40) tahun dengan 51,9% laki-laki. Sebanyak 94,2% subyek mendapatkan terapi anti retrovirus. Nilai median jumlah limfosit T CD4+ adalah 245 (50-861) sel/µL dan 63,5% subyek berada pada kelompok CDC II. Status gizi 84,6% subyek normal dan lebih dengan nilai median 21,4 (14,4-32,4) kg/m2. Nilai rerata asupan energi subyek 1850,8±454,6 kkal/hari, 76,9% subyek memiliki asupan energi kurang dari kebutuhan total harian. Nilai Median asupan lemak subyek 51,4 (22-129,4) gram/hari dan 63,5% subyek memiliki asupan lemak kurang dari energi total. Semua subyek memiliki asupan serat yang kurang dari angka kecukupan serat, nilai rerata asupan serat subyek adalah 8,6±3,6 gram. Nilai rerata asupan beta karoten subyek 10,92±4,37 mg/hari, 88,5% memiliki asupan beta karoten cukup. Nilai median kadar beta karoten subyek 0,21 (0,01-0,72) µmol/L dan 76,9% subyek memiliki kadar beta karoten rendah. Rerata kadar SOD subyek sebesar 1542,1±281 U/gHb dan 53,8% subyek memiliki kadar SOD normal. Tidak didapatkan korelasi bermakna antara kadar beta karoten dengan SOD pada penderita HIV/AIDS (r=-0,174, p=0,217). ......Free radicals formed on the course of HIV infection can cause cellular and multiple organ damage. Antioxidants play an important role to minimize damage caused by these free radicals. This research is done using cross sectional design and is part of a joint study to assess the correlation between antioxidants (beta-carotene, vitamin C, E, and zinc) and SOD levels in HIV/AIDS patients at Pokdisus AIDS FKUI/RSUPNCM, Jakarta. The study is done from late February 2013 to March 2013 using consecutive sampling method, 52 subjects matched the study’s criteria. Study shows the age median value is 33 (24-40) years old, with 51.9% male. As much as 94.2% subjects were receiving anti retroviral therapy. Median value of CD4+ T lymphocyte count is 245 (50-861) cell/µL, 63.5% subjects belong in the CDC II category. Nutritional status for 84.6% subjects was normal and overweight with median value of 21.4 (14.4-32.4) kg/m2. Mean score for energy intake is 1850.8±454.6 kcal/day and as much as 76.9% subjects have energy intake less than total daily requirement. Median value of fat intake is 51.4 (22-129.4) grams/day and 63.5% subjects have fat intake less than total energy. All subjects were found to have fiber intake less than individual fiber requirement with mean score of 8.6±3.6 grams. Subjects’ mean score for beta-carotene is 10.92±4.37 mg/day and 88.5% of the subjects have adequate beta-carotene intake. Median value of beta-carotene level is 0.21 (0.01-0.72) µmol/L and 76.9% subjects have low beta-carotene level. SOD level mean score is 1542.1±281 U/gHb, 53.8% subjects had normal SOD level. This study found no significant correlation between beta-carotene and SOD levels in HIV/AIDS patients (r=-0.174, p=0.217).

Abstrak :
Tujuan : Mengetahui korelasi antara asupan besi. hemoglobin dan kadar feritin serum dengan indikator panjang badan untuk usia pada bayi stunring usia 6-I2 bulan. Tempat : Pada 20 desa dan kelurahan di Kota dan Kabupaten Tangerang di wilayah binaan CARE International Indonesia. Bahan dan cara: Pada penelitian dengan disain potong lintang ini didapatkan 3l subyek sesuai kriteria penelitian. Data yang dikumpulkan meliputi pendidikan formal ibu, status gizi berdasarkan HAZ, asupan kalori, protein dan besi dcngan menggunakan FFQ semikuantitati pemeriksaan laboratorium darah yaitu hemoglobin clan feritin serum. Uji statistik yang digunakan adalah Kolmogorov Smirnov, dan korelasi Pearson/spernmn's Rank. Hasil : Pada penelitian ini didapatkan 5I,6% pendidikan formal ibu sekolah dasar/sederajat. Subyek merupakan kelompok stunting yang sebagian besar (80,6%) merupakan stunting sedang. serata asupan energi adalah 767,99_+;275,42 kkal/hari dan protein 2l,80_~§l l,08 g/hari. Asupan energi dan protein subyek yang rendah 74,2% dan 29% dibandingkan RDA. Rcrata asupan besi adalah 6,06 j 4, l 6 mg/hari, sebagaian besar subyek (8l%) dengan asupan besi kurang menurut RNI. Rerata kadar hemoglobin 10,041 1,32 g/dL dan kadar feritin serum didapatkan median 10,93 (l,62; 90,38) pg/L. Subyek yang mengalami anemia 71%, depiesi besi tanpa anemia 9,7% dan anemia defisiensi besi 41.9°/6. Pada analisis tidak didapatkan korelasi yang bermakna antara asupan besi dengan hemoglobin dan feritin scrum. Pada analisis korelasi antara hemoglobin dan feritin serum dengan HAZ skor tidak didapatkan korelasi bermakna. Kesimpulan : Tidak didapatkan korelasi yang bemiakna antara asupan besi dengan hemoglobin dan feritin serum. Tidak didapatkan korelasi yang bcrmakna antara hemoglobin dan feritin serum dengan HAZ skor.

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Objective :To know correlation between dietary iron intake, hemoglobin, serum feritin and height tbr age Z score in shunting infant age 6-I2 month. Location : 20 villages and kelurahan in Tangerang City and District the area under serviced by CARE, international Indonesia (Cll). Material and Method: A cross sectional study had been canied out on 31 subjects selected. Data collected consist of' respondent (mother) tbmial education, subject characteristic i.e HAZ, dietary intake of energy, protein and iron using semi quantitative FFQ, and laboratory examination lbr hemoglobin and serum ferritin. Statistical analysis was using Kolmogorov-Smimov and Pearson/Spearman?s rank correlation tests. Result : Most of mothers? formal education was primary school (5l.6%). Majority ofthe subjects was in moderate stunting (80,6%). Average energy and protein intake were 767.99i275.42 kcal/day and 2 l,80il l,08 g/day. respectively. Subjects with low energy and protein intake as compared to the RDA are 74.2% and 29%, respectively. Average iron intake 6.061 4.l6 mg/day and 8l% of the subject had iron intake less than RNI. Average hemoglobin level was l0.04=t:l.32 g/dl, whereas median serum ferritin was l0.93 (1.62; 9038) ug/L. Subject with anemia, iron depletion without anemia and iron deficiency anemia were 71%,9.7%, and 4l.9%, respectively. There was no significant correlation between iron intake and hemoglobin. There was negative correlation between iron intake and serum ferritin (p>0.05). No significant correlation was found between hemoglobin and serum ferritin with HAZ score. Conclusion: There were no significant correlations between iron intake with hemoglobin, and serum ferritin. There were no significant correlations between hemoglobin and serum ferritin with HAZ score unstinting infant 6-12 month.

Abstrak :
Abstract The Effect of Vitamin C and E Suplementations on Serum CReaetive Protein Level in Moderate-Severe Bum Patients. To study the effect of vitamin C 1000 mg i.v and E 400 mg oral supplementation on serum c-reactive protein level as parameter of inflammation in bum patients. This study was a one group pre post test that gave i. v 1000 mg vitamin C and ond 400 mg vitamin E supplementations to thirteen moderate-severe bum patients, with percentage of bum less than 60%, in bum unit Cipto Mangunkusumo Hospital. Data were collected using questionnaire, medical record, anthropometric measurement, dietary assessment using fol.lf consecutive days food record. Laboratory test for serum vitamin C, E and serum c-reactivc protein levels were evaluated before and after supplementations. Differences in mean values were assessed by Wilcoxon for the not normal distribution. Results Among thirteen subjects, seven (53.80%) subjects were female, median of age 35 (18-55) years. Body mass index in most subjects (69.2%) were categorized as normal. The median percentages of bum injury 22 (5-57}%, and the frequency of severe bum was 61.50%, while the most cause of bum was flame (76.9%). Level of vitamin C after treatment was increased, but not significant. Level of vitamin E after treatment was significantly increased (!Pi),OI6). Level of CRP after supplementation significantly increased (!Pi).04). Conclusion There was significantly reduced of level serum CRP after four days vitamin CI 000 mg i. v dan E 400 mg ond supplementations.

Abstrak :
Tujuan: Mengetahui efek pemberian nutrisi enteral dua jam pra sectio caesarea terhadap perubahan kadar hsIL-6 pasca sectio caesarea Metode: Penelitian ini merupakan uji klik paralel, yang subyek penelitiannya dipilih secara consecutive sampling, yang dibagi menjadi dua kelompok melalui randomisasi blok masing-masing terdiri dari 10 orang subyek. Data karakteristik awal penelitian meliputi usia, indikasi SC, status gizi berdasarkan KMS ibu hamil dan LiLA, asupan energi dan protein pra SC, lama operasi, jumlah perdarahan, dan hsIL-6 prabedah adalah homogen. Untuk melihat perbedaaan perubahan kadar hsIL-6 dilakukan pemeriksaan hsIL-6 setelah 6 jam pasca insisi. Analisis data dilakukan dengan menggunakan uji t. Batas kemaknaan 5%. Hasil: Peningkatan rerata dan simpang baku kadar hsIL-6 meningkat pada kedua Kelompok. Peningkatan kadar hsIL-6 ( p <0,05) dan perubahan kadar hsIL-6 lebih besar bermakna pada kelompok kontrol dibandingkan kelompok perlakuan (p <0,05). Simpulan: Pemberian nutrisi enteral dua jam pra secfio caesarea dapat menekan peningkatan kadar hsIL-6. ......Objective: To investigate the effect of enteral nutrition that given two hour before caesarean section on changes hsIL-6 levels after caesarean section. Methods: The design study was a parallel clinical trial, in which the subject were selected by consecutive sampling, each proup consisted of ten subjects. The subject were divided into two groups using block randomization. Data collected including age, indication of CS, nutritional status based on MUAC and KMS chart in pregnancy, energy and protein intakes, duration of surgery, amount of blood loss during surgery, and hsIL-6 serum preoperative, were matched at baseline. To investigated the changes of hsIL-6 levels, the concentrations to assessed six hours post CS. Statistical analysis was measured by t-test. The significance levcl was 5%. Results: There was a significant increasc of hsIL-6 levels (p = 0,001) in both groups. The increased and changes of hsIL-6 levels in the control group was significantly higher than in the treatment group. (p<0.05, and p <0,05 respectively). Conclusion: Enteral nutrition that was given two hour before caesarean section can suppress the increased of hsIL-6 levels.

Abstrak :
ABSTRACT Objective : To study the eH`ect of vitamin C 1000 mg i.v and E 400 mg oral supplementation on serum c-reactive protein level as parameter of inflammation in burn patients. Methods: This study was a one group pre post test that gave i.v 1000 mg vitamin C and oral 400 mg vitamin E supplementations to thirteen moderate-severe burn patients, with percentage of burn less than 60%, in burn unit Cipto Mangunkusumo Hospital. Data were collected using questionnaire, medical record, anthropometric measurement, dietary assessment using four consecutive days food record. Laboratory test for serum vitamin C, E and serum c-reactive protein levels- were evaluated before and after supplementations. Differences in mean values were assessed by Wilcoxon for the not normal distribution. Results: Among thirteen subjects, Seven (53.80%) Subjects were female, median of age 35 (18-55) years. Body mass index in most subjects (69.2%) were categorized as normal. The median percentages of burn injury 22 (5~57)%, and the frequency of severe burn was 6l.50%, while the most cause of burn was flame (76.9%). Level of vitamin C after treatment was increased, but not significant. Level of vitamin E after treatment was significantly increased (p=0,016). Level of CRP after supplementation significantly increased (p=0.04). Conclussion: There was significantly reduced of level serum CRP after four days vitamin C1000 mg i.v dan E 400 mg oral supplementations.

Abstrak :
Sekitar 60-70% hipertensi pada orang dewasa berhubungan dengan kelebihan lemak tubuh yang berhubungan peningkatan kadar angiotensinogen (AGT) yang berperan dalam peningkatan tekanan darah. Penelitian ini bertujuan untuk mengetahui korelasi persentase lemak tubuh, indeks massa tubuh (IMT), dan lingkar pinggang (LP) dengan kadar AGT plasma pada penderita hipertensi etnik Minangkabau. Sebanyak 63 orang penderita hipertensi, berusia 35–54 tahun, di Padang diambil secara konsekutif. Pada seluruh subyek dilakukan wawancara untuk mengetahui karakteristik dan aktivitas fisik. Penilaian asupan makanan, pengukuran persentase lemak tubuh, antropometri dan pemeriksaan kadar AGT plasma juga dilakukan. Data dianalisis menggunakan uji t tidak berpasangan dan uji korelasi. Rerata asupan lemak lebih besar dibading yang dianjurkan untuk orang Indonesia. Rerata persentase lemak tubuh subyek penelitian adalah 37,45 ± 5,95% (pada subyek laki-laki 27,70 ± 2,58 dan pada subyek perempuan 38,29 ± 5,38) dan rerata IMT 26,83 ±3,59 kg/m2. Sebanyak 92,1% subyek mepunyai LP yang lebih besar dari nilai normal. Rerata kadar AGT plasma 40.113 ± 8,033 ng/mL. Tidak terdapat hubungan yang bermakna antara jenis kelamin dan usia dengan kadar AGT plasma. Persentase lemak tubuh mempunyai korelasi yang sedang dengan kadar AGT plasma (r=0,426; p<0,001), begitu juga korelasi IMT dengan kadar AGT plasma (r=0,418; p=0,001), sedangkan korelasi LP dengan kadar AGT lemah (r=0,378; p=0,002). Hasil ini menunjukkan bahwa terdapat korelasi derajat sedang antara persentase lemak tubuh dan IMT dengan kadar AGT plasma penderita hipertensi etnik Minangkabau, sedangkan korelasi LP dengan kadar AGT plasma lemah. ......Approximately 60-70% of hypertension in adults associated with obesity that related with increased of pasma angiotensinogen (AGT) levels. This study aimed to determine the correlation of percentage body fat, body mass index (BMI) and wrist circumference (WC) with plasma AGT levels in hypertensive Minangkabau ethnic. Sixty three hypertensive patients, 35–54 years old, in Padang were enrolled consecutively. All subjects were interviewed to determine the characteristics and physical activity. Food intake assessment, body fat percentage measurement, anthropometric and plasma AGT levels examination were done. Data were analyzed using unpaired t-test and correlation test. The mean fat intake is greater than suggested for Indonesian. The mean body fat percentage of subjects is 27.70 ± 2.58 in male subjects and 38.29 ± 5.38 in female subjects, and the mean BMI is 26.83 ± 3.59 kg/m2. A total of 92.1% of subjects have WC larger than normal value. The mean plasma levels of AGT 40.113 ± 8.033 ng/mL. There was no significant relationship between gender and age with plasma AGT levels. Percentage of body fat has moderate correlation with plasma AGT levels (r = 0.426, p <0.001), as well as correlation of IMT with plasma AGT levels (r=0.418, p=0.001), and correlation of WC with plasma AGT level is weak (r=0.378, p=0.002). These result show a moderate correlation between body fat percentage and BMI with plasma AGT levels in hypertensive Minangkabau ethnic group. There is also a weak correlation between WC with plasma AGT levels.