Hasil Pencarian  ::  Simpan CSV :: Kembali

Hasil Pencarian

Ditemukan 55 dokumen yang sesuai dengan query
cover
Saragih, Riahdo Juliarman
Abstrak :
Latar Belakang: Ventilator-associated pneumonia (VAP) merupakan infeksi yang sering terjadi di intensive care unit (ICU) dan memiliki angka mortalitas yang tinggi. Pengetahuan tentang prediktor mortalitas dapat membantu pengambilan keputusan klinis untuk tatalaksana pasien. Studi-studi tentang faktor prediktor mortalitas VAP menunjukkan hasil yang berbeda-beda dan tidak ada penelitian yang komprehensif di Indonesia. Tujuan: Mengetahui faktor-faktor prediktor mortalitas pasien VAP di RSCM. Metode: Penelitian ini merupakan studi kohort retrospektif pada pasien ICU RSCM yang didiagnosis VAP selama tahun 2003-2012. Data klinis dan laboratorium beserta status luaran (hidup atau meninggal) selama perawatan diperoleh dari rekam medis. Analisis bivariat dilakukan pada variabel kelompok usia, infeksi kuman risiko tinggi, komorbiditas, renjatan sepsis, kultur darah, prokalsitonin, ketepatan antibiotik empiris, acute lung injury, skor APACHE-II, dan hipoalbuminemia. Variabel yang memenuhi syarat akan disertakan pada analisis multivariat regresi logistik. Hasil: Sebanyak 201 pasien diikutsertakan pada penelitian ini. Didapatkan angka mortalitas selama perawatan sebesar 57,2%. Kelompok usia, komorbiditas, renjatan sepsis, prokalsitonin, ketepatan antibiotik empiris, dan skor APACHE II merupakan variabel yang berpengaruh terhadap mortalitas pada analisis bivariat. Prediktor mortalitas pada analisis multivariat adalah antibiotik empiris yang tidak tepat (OR 4,70; IK 95% 2,25 sampai 9,82; p < 0,001), prokalsitonin > 1,1 ng/mL (OR 4,09; IK 95% 1,45 sampai 11,54; p = 0,01), usia ≥ 60 tahun (OR 3,71; IK 95% 1,35 sampai 10,20; p = 0,011), dan adanya renjatan sepsis (OR 3,53; IK 95% 1,68 sampai 7,38; p = 0,001). Kesimpulan: Pemberian antibiotik empiris yang tidak tepat, prokalsitonin yang tinggi, usia 60 tahun atau lebih, dan adanya renjatan sepsis merupakan pediktor independen mortalitas pada pasien VAP. ......Background: Ventilator-associated pneumonia (VAP) is a frequent infection with high mortality rates in intensive care unit (ICU). The prediction of outcome is important in decision-making process. Studies exploring predictors of mortality in patients with VAP produced conflicting results and there are no comprehensive reports in Indonesia. Objective: To determine predictors of mortality in patients with VAP in Cipto Mangunkusumo Hospital. Methods: We performed a retrospective cohort study on patients admitted to the ICU who developed VAP between 2003?2012. Clinical and laboratory data along with outcome status (survive or non-survive) were obtained for analysis. We compared age, presence of high risk pathogens infection, presence of comorbidity, septic shock status, blood culture result, procalcitonin, appropriateness of initial antibiotics therapy, presence of acute lung injury, APACHE II score, and serum albumin between the two outcome group. Logistic regression analysis performed to identify independent predictors of mortality. Results: A total of 201 patients were evaluated in this study. In-hospital mortality rate was 57.2%. Age, comorbidity, septic shock status, procalcitonin, appropriateness of initial antibiotics therapy, and APACHE II score were significantly different between outcome groups. The independent predictors of mortality in multivariate logistic regression analysis were inappropriate initial antibiotics therapy (OR: 4.70; 95% CI 2.25 to 9.82; p < 0.001), procalcitonin > 1.1 ng/mL (OR: 4.09; 95% CI 1.45 to 11.54; p = 0.01), age ≥ 60 years old (OR: 3.71; 95% CI 1.35 to 10.20; p = 0.011), and presence of septic shock (OR: 3.53; 95% CI 1.68 to 7.38; p = 0.001). Conclusion: Inappropriate initial antibiotic therapy, high serum procalcitonin level, age 60 years or older, and presence of septic shock were independent predictors of mortality in patients with VAP.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2013
T-pdf
UI - Tesis Membership  Universitas Indonesia Library
cover
Niken Churniadita Kusumastuti
Abstrak :
ABSTRAK
Imbang nitrogen pada pasien sakit kritis selalu negatif akibat respon stres. Pada lansia perubahan metabolismenya berisiko memperburuk imbang nitrogen. Tujuan penelitian ini adalah untuk mengetahui imbang nitrogen dan hubungannya dengan asupan energi dan protein pada lansia sakit kritis dalam 48 jam pertama di ICU. Penelitian ini menggunakan metode potong lintang, consecutive sampling. Subyek penelitian adalah 26 lansia sakit kritis. Hasil penelitian pada 24 jam I dan II adalah; imbang nitrogen -5,2 (-31,2 − -4,1) g dan -4,5+4,6; asupan energi 78,8+45,0% dan 91,1+50,2% terhadap target; asupan protein 0,57+0,35 g/kgBB/hari dan 0,71+0,37 g/kgBB/hari serta terdapat korelasi positif bermakna antara imbang nitrogen dengan asupan energi; r=0,6 dan r=0,5 dan korelasi positif bermakna antara imbang nitrogen dengan asupan protein; r=0,5 dan r=0,4. Kesimpulan penelitian ini adalah terdapat hubungan bermakna antara imbang nitrogen dengan asupan energi dan protein pada lansia sakit kritis
ABSTRAK
Nitrogen balance in criticaly ill patients tend to be negative due to stress response. In the elderly patients, the metabolic changes risk to worsening nitrogen balance.The aim of this study is to determine nitrogen balance and its relation with energy and protein intake in critically ill elderly patients within 48 hours in ICU. The study was cross sectional, consecutive sampling on 26 subjects. The nitrogen balances were -5.2 (-31.2 − -4.1) g and -4.5+4.6 g; energy intakes were 78.8+45.0% and 91.1+50.2% target; protein intakes were; 0.57+0.35 g/kgBW/d and 0.71+0.37 g/kgBW/d. There were positive correlation between nitrogen balance and energy intake; r=0.6 and r=0.5, and between nitrogen balance and protein intake; r=0.5 and r=0.4 in 24 hours I and II respectively. The conclusion is there were positive correlation between nitrogen balance with energy and protein intakes.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
cover
Siti Pratiekauri
Abstrak :
Aspergilosis invasif AI merupakan infeksi jamur invasif disebabkan Aspergillus spp sedangkan aspergilosis paru invasif API merupakan manifestasi AI yang sering ditemukan Gejala klinis laboratorium rutin dan radiologis tidak khas sehingga sering terjadi keterlambatan diagnosis dan tatalaksana Pemeriksaan biopsi tidak selalu dapat dilakukan dan berisiko tinggi sedangkan pemeriksaan biakan memiliki keterbatasan sensitivitas dan waktu Deteksi antigen galaktomanan GM merupakan uji penapis AI yang dinilai baik tetapi di Indonesia kit GM tidak rutin tersedia dan mahal sehingga perlu dicari uji diagnostik alternatif antara lain menggunakan deteksi antibodi anti Aspergillus yang sederhana mudah murah dan terjamin ketersediaannya Tujuan penelitian ini membandingkan hasil pemeriksaan deteksi antibodi anti Aspergillus metode immunodiffusion test IDT menggunakan crude antigen Aspergillus dengan deteksi antigen GM serta mengetahui nilai sensitivitas dan spesifisitasnya Penelitian berdisain potong lintang ini merupakan bagian dari penelitian multisenter sebelumnya mengenai insidens API pada 405 pasien ICU di 6 rumah sakit di Jakarta Selanjutnya ditentukan 125 pasien non neutropenia diduga AI yang bahan klinisnya menjalani pemeriksaan uji diagnostik di atas Biakan Aspergillus sp tumbuh pada bahan klinis ekskreta paru yang dimiliki 26 dari 125 pasien tersebut 20 8 Diagnosis AI putative ditegakkan pada 26 pasien 6 2 dari 405 pasien keseluruhan Dari 125 pasien yang diperiksa uji GM positif ditemukan pada 62 pasien 48 6 sedangkan uji IDT positif pada 74 pasien 59 2 Analisis statistik menunjukkan tidak terdapat perbedaan bermakna antara hasil uji GM dan uji IDT tetapi nilai kesetaraannya sangat lemah nilai kappa 0 169 Uji IDT menggunakan crude antigen Aspergillus mempunyai sensitivitas 67 7 dan spesifisitas 49 1 ......Invasive aspergillosis IA is an invasive fungal infections caused by Aspergillus spp while invasive pulmonary aspergillosis IPA is the most common manifestation of IA Clinical symptoms routine laboratory and radiological features are not typical and could lead to diagnosis and treatment delayed Biopsy is high risk and not always possible to be performed whereas culture examination has limited sensitivity and time consumed Galactomannan GM antigen detection is good for IA screening but the kit is expensive and not routinely available in Indonesia It is necessary to find an alternative tests such as detection of anti Aspergillus antibody which is simple inexpensive and more available This study aims to determine the sensitivity and specificity of immunodiffusion test IDT for detecting anti Aspergillus antibody using crude antigen compare to GM antigen detection on diagnosis of IA This cross sectional study is part of previous multicenter study on incidence of IA in ICU patients at six hospitals in Jakarta 405 patients Then clinical materials of 125 non neutropenic patients suspected IA were determined to undergo both clinical diagnostic tests Aspergillus sp were isolated from clinical materials of lung excreta from 26 out of 125 patients 20 8 Putative IA was diagnosed in 26 patients 6 2 out of 405 patients From 125 patients examined GM positive test was found in 62 patients 48 6 while IDT test positive in 74 patients 59 2 Statistical analysis showed no significant differences between the results of IDT test compared to GM but the equality value is very weak kappa 0 169 IDT test using crude Aspergillus antigen has a sensitivity of 67 7 and specificity of 49 1 ; Invasive aspergillosis IA is an invasive fungal infections caused by Aspergillus spp while invasive pulmonary aspergillosis IPA is the most common manifestation of IA Clinical symptoms routine laboratory and radiological features are not typical and could lead to diagnosis and treatment delayed Biopsy is high risk and not always possible to be performed whereas culture examination has limited sensitivity and time consumed Galactomannan GM antigen detection is good for IA screening but the kit is expensive and not routinely available in Indonesia It is necessary to find an alternative tests such as detection of anti Aspergillus antibody which is simple inexpensive and more available This study aims to determine the sensitivity and specificity of immunodiffusion test IDT for detecting anti Aspergillus antibody using crude antigen compare to GM antigen detection on diagnosis of IA This cross sectional study is part of previous multicenter study on incidence of IA in ICU patients at six hospitals in Jakarta 405 patients Then clinical materials of 125 non neutropenic patients suspected IA were determined to undergo both clinical diagnostic tests Aspergillus sp were isolated from clinical materials of lung excreta from 26 out of 125 patients 20 8 Putative IA was diagnosed in 26 patients 6 2 out of 405 patients From 125 patients examined GM positive test was found in 62 patients 48 6 while IDT test positive in 74 patients 59 2 Statistical analysis showed no significant differences between the results of IDT test compared to GM but the equality value is very weak kappa 0 169 IDT test using crude Aspergillus antigen has a sensitivity of 67 7 and specificity of 49 1 ; Invasive aspergillosis IA is an invasive fungal infections caused by Aspergillus spp while invasive pulmonary aspergillosis IPA is the most common manifestation of IA Clinical symptoms routine laboratory and radiological features are not typical and could lead to diagnosis and treatment delayed Biopsy is high risk and not always possible to be performed whereas culture examination has limited sensitivity and time consumed Galactomannan GM antigen detection is good for IA screening but the kit is expensive and not routinely available in Indonesia It is necessary to find an alternative tests such as detection of anti Aspergillus antibody which is simple inexpensive and more available This study aims to determine the sensitivity and specificity of immunodiffusion test IDT for detecting anti Aspergillus antibody using crude antigen compare to GM antigen detection on diagnosis of IA This cross sectional study is part of previous multicenter study on incidence of IA in ICU patients at six hospitals in Jakarta 405 patients Then clinical materials of 125 non neutropenic patients suspected IA were determined to undergo both clinical diagnostic tests Aspergillus sp were isolated from clinical materials of lung excreta from 26 out of 125 patients 20 8 Putative IA was diagnosed in 26 patients 6 2 out of 405 patients From 125 patients examined GM positive test was found in 62 patients 48 6 while IDT test positive in 74 patients 59 2 Statistical analysis showed no significant differences between the results of IDT test compared to GM but the equality value is very weak kappa 0 169 IDT test using crude Aspergillus antigen has a sensitivity of 67 7 and specificity of 49 1
Jakarta: Fakultas Kedokteran, 2016
SP-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
cover
Hadli Rokyama
Abstrak :
ABSTRAK
Latar belakang: Penggunaan kateter vena sentral yang semakin banyak seiring meningkatnya mutu pelayanan kesehatan di kamar operasi dan ruang rawat intensif membuat risiko komplikasi juga semakin meningkat. Ultrasonografi direkomendasikan untuk menurunkan insiden komplikasi kanulasi vena jugularis interna. Namun, keterbatasan akses dan ketersedian ultrasonografi membuat metode penanda anatomi masih diminati walaupun insiden komplikasi mencapai 19 Merrer, 2011 , sehingga posisi yang tepat diharapkan dapat mengurangi insiden komplikasi. Rotasi kepala pada sudut tertentu mempengaruhi posisi vena jugularis interna dan arteri karotis. Penelitian ini bertujuan ingin mengetahui pengaruh rotasi kepala kontra lateral terhadap jarak dan overlapping vena jugularis interna terhadap arteri karotis setinggi kartilago krikoid dengan bantuan ultrasonografi pada ras Melayu di Indonesia.Metode: Penelitian ini bersifat analitik observasional denga rancangan potong lintang pada pasien yang menjalani operasi bedah terencana di Instalasi Bedah Pusat RSUPN Ciptomangunkusumo Jakarta. Setelah mendapatkan izin komite etik dan informed consent sebanyak 34 subyek diambil dengan metode consecutive sampling pada bulan Oktober 2016. Jarak dan rasio overlapping vena jugularis interna terhadap arteri karotis setinggi kartilago krikoid diukur dengan menggunakan ultrasonografi dua dimensi pada sudut rotasi kontra lateral 0o, 30o, 45o, 60o. Data diolah menggunakan program SPSS 21. Uji Anova digunakan untuk melihat hubungan jarak vena dan rasio overlapping jugularis interna terhadap arteri karotis dilanjutkan dengan uji post hoc Tukey.Hasil: Terdapat perbedaan yang bermakna jarak dan overlapping vena jugularis interna dan arteri karotis setinggi kartilago krikoid pada ras Melayu di Indonesia pada sudut rotasi kepala kontra lateral 0o, 30o, 45o, 60o p < 0,001 . Terdapat hubungan antara berat badan dan tinggi badan terhadap rasio overlapping vena jugularis interna dan arteri karotis. Tidak Terdapat hubungan antara jenis kelamin, usia dan Indeks Massa Tubuh IMT terhadap rasio overlapping vena jugularis interna dan arteri karotis.Simpulan: Terdapat pengaruh rotasi kepala kontra lateral terhadap jarak dan overlapping vena jugularis interna dan arteri karotis setinggi kartilago krikoid dengan bantuan ultrasonografi pada ras Melayu di Indonesia.Kata kunci: rotasi kepala kontra lateral, jarak dan overlapping vena jugularis interna dan arteri karotis, ras Melayu ABSTRACT Background The use of central venous catheters are widely increasing as well as improvement of health care quality in the operating theather and the intensive care unit. Complication incidences also increasing too. Ultrasound is recommended to decrease complication of internal jugular vein cannulation. However, limited access and availability to ultrasound makes anatomical landmark methods still in demand even though the incidence of complications was 19 Merrer, 2011 , exact position is expected to reduce the incidence of complications. Certain head rotation the position of the internal jugular vein and carotid artery. This study aims the effect of contra lateral head rotation to distance and overlapping of internal jugular vein and carotid artery at cricoid cartilage level by ultrasound guidance on the Malay race in Indonesia. Methods This study was analytical observational with cross sectional design in patients undergone elective surgery at Central Surgery Unit RSUPN Ciptomangunkusumo Jakarta. After getting approval from ethics committee and informed consent, 34 subjects were taken with consecutive sampling method in October 2016. Distance and overlapping ratio the internal jugular vein to carotid artery at cricoid level was measured using two dimensional ultrasound in contra lateral head rotation angle of 0o, 30o, 45o, 60o. The data were processed using SPSS 21. Anova test used to view the relationships within the vein and internal jugular overlapping ratio of the carotid artery followed by post hoc Tukey test. Results There were significant differences on distance and overlapping of the internal jugular vein and carotid artery at cricoid level on the Malay race in Indonesia at contra lateral head rotation angle 0o, 30o, 45o, 60o p
Fakultas Kedokteran Universitas Indonesia, 2017
T55670
UI - Tugas Akhir  Universitas Indonesia Library
cover
Julian Fitra
Abstrak :
ABSTRAK
LatarBelakang: Menentukan prediktor yang paling akurat dalam menilai sulitvisualisasi laring(DVL) dengan menggunakan skor mallampati (MMT) , Jarak sternomental(SMD) dan jarak buka mulut(IIG), baik secara tunggal maupun dalam kombinasi. Metode: Sebanyak 283 pasien ikut serta dalam penelitian dan dievaluasi kemungkinan mereka mengalami sulit visualisasi laring. Kesulitan visualisasi laring dinilai dengan laringoskopi langsung berdasarkan klasifikasi Cormack Lehane (CL). Skor CL derajat III dan IV ditentukan sebagai sulit visualisasi laring. Kondisi ini juga diperkirakan dengan menggunakan prediktor jalan napas, yaitu MMT, SMD dan IIG. Titik potong untuk masing-masing prediktor adalah skor Mallampati III dan IV, ≤ 12,5 cm, dan ≤ 3 cm. Selanjutnya, ditentukan nilai sensitivitas, spesifisitas, nilai prediksi positif dan negatif serta nilai area di bawah kurva (AUC) dari setiap prediktor tersebut, baik secara tunggal maupun dalam kombinasi. Prediktor independen DVL ditentukan dengan melakukan analisis regresi logistik. Hasil: Sulit visualisasi laring ditemukan pada 29 (10,2%) subyek penelitian. Nilai sensitivitas, spesifisitas, prediksi positif dan luas AUC prediktor jalan napas adalah: MMT (20,8%; 99,7%; 71,4%; 68%), SMD (72,4%; 97,2%; 75%; 88%), dan IIG (41,4%; 99,4%; 85,7%; 73%). Penelitian kami menunjukkan bahwa kombinasi prediktor terbaik adalah gabungan prediktor SMD + IIG. Kombinasi tiga prediktor MMT + SMD + IIG ternyata menunjukkan nilai AUC yang sama dengan kombinasi dua prediktor SMD + IIG. Kesimpulan: Penelitian ini menganjurkan gabungan prediktor IIG + SMD sebagai model diagnostik yang optimal untuk memperkirakan sulit visualisasi laring pada populasi ras Melayu di Indonesia.
ABSTRAK
Background: To determine the most accurate predictor in evaluating difficult visualization of larynx (DVL) using indicators of modified mallampati test (MMT), sternomental distance (SMD) and inter incisor gap (IIG), either in isolation or in combination. Methods: Two hundred eighty three patients were participated in the study and evaluated for their possibility of having DVL. The difficulty of larynx visualization was evaluated using direct laryngoscopy based on grading of the Cormack and Lehane (CL) classification. The CL grades III and IV were considered as difficult visualization of larynx. DVL was also predicted using the airway predictors of MMT, SMD and IIG. The cut-off points for the airway predictors were Mallampati III and IV; ≤ 12,5 cm, and ≤ 3 cm, respectively. Moreover, sensitivity, specificity, positive and negative predictive value and area under the curve (AUC) of each predictor were determined, either in isolation or in combination. Independent predictors of DVL were determined using logistic regression analysis. Results: Difficulty to visualize the larynx was found in 29 (10.2%) subjects. The sensitivity, specificity, positive predictive value and AUC for the airway predictors were: MMT (20.8%; 99.7%; 71.4%; 68%), SMD (72.4%; 97.2%; 75%; 88%), and IIG (41.4%; 99.4%; 85.7%; 73%). The best combination of predictors was SMD + IIG with an AUC of 90.2%. Triple combination of MMT + SMD + IIG showed the same value of AUC with combination of two predictors, SMD + IIG. Conclusion: This study suggests the combination of IIG + SMD predictors as the optimal diagnostic model to predict DVL in a Malay race population in Indonesia.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
cover
Peni Yulia Nastiti
Abstrak :
ABSTRAK
LATAR BELAKANG: Hipoperfusi perioperatif yang diawali oleh hipoperfusi splanknik meningkatkan morbiditas dan mortalitas pada pasien pascaoperasi risiko tinggi. Parameter kadar laktat, P(cv-a)CO2 dan konsentrasi ScvO2 darah dapat digunakan untuk menilai hipoperfusi global. Peningkatan volume residu lambung dihubungkan dengan terjadinya hipoperfusi regional saluran cerna. Penelitian ini bertujuan mengetahui korelasi parameter hipoperfusi global (laktat, P(cv-a)CO2, ScvO2) dengan volume residu lambung pada pasien pascaoperasi risiko tinggi yang dirawat di ICU RSCM. METODE: Sebanyak 48 subyek penelitian yang dianalisis didapatkan dengan metode consecutive sampling. Subyek penelitian yaitu pasien usia ≥18 tahun yang memenuhi kriteria pascaoperasi risiko tinggi, dapat dipasang pipa oro/nasogastrik, pasien tidak menolak diikutsertakan dalam penelitian, bukan pascaoperasi gastrektomi, tidak ada hematemesis, pasien tidak dengan gastrostomi, tidak diberikan opioid pascabedah, serta dilakukan pemasangan kateter vena sentral pada v. cava superior. Pasien akan dikeluarkan dari penelitian apabila pasien meninggal dan dilakukan resusitasi jantung paru sebelum 24 jam pascaoperasi, diberikan opioid. Pasien dirawat di ICU pascaoperasi dan dicatat volume residu lambung, kadar laktat, P(cv-a)CO2, konsentrasi ScvO2 pada jam ke-0, ke-8 dan 24. HASIL: Terdapat korelasi lemah antara kadar laktat dengan volume residu lambung pada jam ke-0 (r=0,301 p<0,05), jam ke-8 (r=0,374 p<0,01) dan jam ke-24 (r=0,314 p<0,05). Tidak terdapat korelasi antara kadar P(cv-a)CO2 dan ScvO2 dengan volume residu lambung pada jam ke-0,8 dan 24. KESIMPULAN: Tidak terdapat korelasi antara parameter hipoperfusi global (laktat, P(cv-a)CO2, ScvO2) dengan volume residu lambung.
ABSTRACT
Perioperative hypoperfusion preceded by splanchnic hypoperfusion increased morbidity and mortality in high risk surgical patients. Parameter levels of blood lactate, P(cv-a)CO2 and concentration ScvO2 can be used to assess global hypoperfusion. Increased gastric residual volume associated with the occurrence of gastrointestinal regional hypoperfusion. This study aims to determine the correlation parameter global hypoperfusion (lactate, P(cv-a)CO2, ScvO2) with gastric residual volume in high risk surgical patients admitted to the ICU RSCM. METHODS: A total of 48 subjects analyzed were obtained by consecutive sampling method. The subjects are patients aged ≥ 18 years who meet the criteria of high risk surgical patients, can be mounted oro/ nasogastric tube, patients did not refuse to be included in this study, not postoperative gastrectomy, no hematemesis, without gastrostomy, not given opioid postoperatively, do the insersion of central venous catheter in v. cava superior. Patient will be excluded from the study if the patient died and performed CPR before 24 hours, administered opioid. Patients admitted to the ICU postoperatively and recorded gastric residual volume, levels of lactate, P(cv-a)CO2 , ScvO2 concentration at 0, 8th and 24th hour. RESULTS: There is a weak correlation between lactate level with gastric residual volume at 0 hour(r=0.301, p<0.05), 8th hour(r=0.374, p<0.01) and 24th hour (r=0.314, p<0.05). There is no correlation between P(cv-a)CO2 level and ScvO2 concentration with gastric residual volume at 0, 8th and 24th hour. CONCLUSION: There was no correlation between the parameters of global hypoperfusion (lactate, P(cv-a)CO2, ScvO2) with gastric residual volume.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
cover
Pittara Pansawira
Abstrak :
ABSTRAK
Hiperglikemia sering terjadi pada pasien sakit kritis dan dapat menimbulkan volume residu lambung tinggi. Penelitian ini bertujuan untuk mengetahui hubungan status hiperglikemia dengan status volume residu lambung tinggi pada pasien dewasa sakit kritis dalam 24 jam I dan II di ICU. Rancangan studi potong lintang, consecutive sampling, pada 96 subjek. Hasil penelitian, terdapat 45,8% subjek mengalami hiperglikemia pada 24 jam I dan 35,4% pada 24 jam II. Terdapat 28,1% subjek mengalami volume residu lambung tinggi pada 24 jam I dan 25% pada 24 jam II. Kesimpulannya, pada penelitian ini tidak didapatkan hubungan yang bermakna antara status hiperglikemia dengan status volume residu lambung tinggi.
ABSTRAK
Hyperglycemia commonly occurs in critically ill patients and can cause high gastric residual volume. The aim of this study is to determine the relationship between hyperglycemia status and high gastric residual volume status in adult critically ill patients within the first and second 24 hours of admission in ICU. The design was cross sectional with consecutive sampling in 96 subjects. There were 45.8% subjects who had hyperglycemia in the first 24 hours and 35.4% in the second. There were 28.1% subjects who had high gastric residual volume in the first 24 hours and 25% in the second. In conclusion, there was no significant relationship between hyperglycemia status and high gastric residual volume status in this study.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
cover
Masry
Abstrak :
[ABSTRAK
Latar Belakang. Manajemen jalan nafas merupakan salah satu tahap yang paling penting dalam bidang anestesiologi. Salah satu jenis Alat bantu jalan nafas yang telah dipergunakan secara luas adalah Laringeal Mask Airway (LMA/Sungkup Laring). Pada pemasangan sungkup laring tanpa menggunakan pelumpuh otot membutuhkan kedalaman anestesi yang cukup, Tes klinis yang mudah, akurat dan aplikatif diperlukan untuk menghindari terjadinya komplikasi. Penelitian ini bertujuan untuk membandingkan trapezius squeezing test dan jaw thrust sebagai indikator kedalaman anestesi pada pemasangan sungkup laring dengan propofol sebagai agen induksi Metode. Sebanyak 128 pasien di randomisasi ke dalam 2 kelompok yaitu jaw thrust dan trapezius squeezing test. Seluruh pasien mendapatkan premedikasi dengan midazolam 0.05 mg/kgBB dan Fentanyl 1 mcg/kgBB. Induksi menggunakan propofol titrasi. Manuver jaw thrust dan trapezius squeezing test dilakukan setiap 15 detik. Saat respon motorik hilang dilakukan pemasangan sungkup laring. Dicatat keberhasilan pemasangan, dosis propofol, tekanan darah, laju jantung, dan insiden apneu. Hasil. Keberhasilan pada kelompok jaw thrust 93.8%, sedangkan trapezius squeezing test yang 90.6%. Penggunaan rerata propofol pada kelompok jaw thrust yaitu sebesar 120.34 mg, sedangkan pada kelompok trapezius squeezing test yaitu sebesar 111,86 mg. Insiden apneu yang pada kelompok jaw thrust terjadi pada 10 (15.6%) pasien, sedangkan pada kelompok trapezius squeezing test sebesar 11 (17.2%) pasien. Tidak terdapat perubahan hemodinamik yang berarti pada kelompok jaw thrust sedangkan sedangkan pada kelompok trapezius squeezing test terdapat perubahan hemodinamik yang berarti di menit ke 3 dan ke 4 Kesimpulan. Trapezius squeezing test tidak lebih baik daripada jaw thrust sebagai indikator klinis dalam menilai kedalaman anestesia pada insersi sungkup laring.
ABSTRACT
Background. Airway management is one of the most important phase in anesthesiology. One of airway device that have been used generally is Laryngeal Mask Airway (LMA). Laryngeal mask insertion without muscle relaxant requires a level of depth anesthesia. An easy, accurate, an applicable clinical indicator were required to avoid complication. This study was determine the comparison trapezius squeezing test and jaw thrust as indicator of depth of anesthesia in laryngeal mask insertion with propofol as induction agent. Methods. 128 patient have been randomize in to 2 group that are jaw thrust and trapezius squeezing test. All patients were received premedication with midazolam 0.05 mg/kg and fentanyl 1 μg/kg. Induction were done by propofol titration. Jaw thrust and trapezius squeezing test maneuver were done in every 15 second. When motoric respond negative the laryngeal mask were inserted. The successful of laryngeal mask insertion was recorded, propofol consumption, blood pressure, heart rate, and incidence of apnea were also documented. Result. Laryngeal mask successfully inserted in 93.8% patients in jaw thrust group, and 90.6% in trapezius squeezing test group. Mean of propofol consumption in jaw thrust group is 120.34 mgs, and in trapezius squeezing test is 11.86 mgs. Incident of apnea in jaw thrust group happened in 10 patients (15.6%), and in trapezius squeezing test group happened in 11 patient (17.2%). Hemodynamic in jaw thrust group relatively stable but in trapezius squeezing test there is significant hemodynamic changing in minute third and fourth. Conclusion. Trapezius squeezing test is not better than jaw thrust as clinical indicators of depth of anesthesia for laryngeal mask insertion.;Background. Airway management is one of the most important phase in anesthesiology. One of airway device that have been used generally is Laryngeal Mask Airway (LMA). Laryngeal mask insertion without muscle relaxant requires a level of depth anesthesia. An easy, accurate, an applicable clinical indicator were required to avoid complication. This study was determine the comparison trapezius squeezing test and jaw thrust as indicator of depth of anesthesia in laryngeal mask insertion with propofol as induction agent. Methods. 128 patient have been randomize in to 2 group that are jaw thrust and trapezius squeezing test. All patients were received premedication with midazolam 0.05 mg/kg and fentanyl 1 μg/kg. Induction were done by propofol titration. Jaw thrust and trapezius squeezing test maneuver were done in every 15 second. When motoric respond negative the laryngeal mask were inserted. The successful of laryngeal mask insertion was recorded, propofol consumption, blood pressure, heart rate, and incidence of apnea were also documented. Result. Laryngeal mask successfully inserted in 93.8% patients in jaw thrust group, and 90.6% in trapezius squeezing test group. Mean of propofol consumption in jaw thrust group is 120.34 mgs, and in trapezius squeezing test is 11.86 mgs. Incident of apnea in jaw thrust group happened in 10 patients (15.6%), and in trapezius squeezing test group happened in 11 patient (17.2%). Hemodynamic in jaw thrust group relatively stable but in trapezius squeezing test there is significant hemodynamic changing in minute third and fourth. Conclusion. Trapezius squeezing test is not better than jaw thrust as clinical indicators of depth of anesthesia for laryngeal mask insertion., Background. Airway management is one of the most important phase in anesthesiology. One of airway device that have been used generally is Laryngeal Mask Airway (LMA). Laryngeal mask insertion without muscle relaxant requires a level of depth anesthesia. An easy, accurate, an applicable clinical indicator were required to avoid complication. This study was determine the comparison trapezius squeezing test and jaw thrust as indicator of depth of anesthesia in laryngeal mask insertion with propofol as induction agent. Methods. 128 patient have been randomize in to 2 group that are jaw thrust and trapezius squeezing test. All patients were received premedication with midazolam 0.05 mg/kg and fentanyl 1 μg/kg. Induction were done by propofol titration. Jaw thrust and trapezius squeezing test maneuver were done in every 15 second. When motoric respond negative the laryngeal mask were inserted. The successful of laryngeal mask insertion was recorded, propofol consumption, blood pressure, heart rate, and incidence of apnea were also documented. Result. Laryngeal mask successfully inserted in 93.8% patients in jaw thrust group, and 90.6% in trapezius squeezing test group. Mean of propofol consumption in jaw thrust group is 120.34 mgs, and in trapezius squeezing test is 11.86 mgs. Incident of apnea in jaw thrust group happened in 10 patients (15.6%), and in trapezius squeezing test group happened in 11 patient (17.2%). Hemodynamic in jaw thrust group relatively stable but in trapezius squeezing test there is significant hemodynamic changing in minute third and fourth. Conclusion. Trapezius squeezing test is not better than jaw thrust as clinical indicators of depth of anesthesia for laryngeal mask insertion.]
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2015
T58675
UI - Tesis Membership  Universitas Indonesia Library
cover
Meliani Anggreni
Abstrak :
Latar Belakang. Puasa sebelum pembiusan merupakan hal yang lazim dilakukan untuk menghindari aspirasi perioperatif. Lama puasa dapat menentukan volume lambung yang tersisa. Puasa yang terlalu singkat dapat meningkatkan risiko aspirasi, namunpuasa yang berkepanjangan dapat menyebabkan dehidrasi dan hipoglikemia. Penelitian ini bertujuan untuk menganalisa volume lambung setelah puasa 6 jam dan 8 jam setelah makan padat pada pasien yang akan menjalani operasi elektif. Metode. Penelitian ini merupakan studi kohort terhadap 37 subjek penelitian selama Januari hingga Februari 2019. Subjek penelitian adalah pasien yang akan menjalani pembedahan elektif non-disgestif di RSUPN Dr. Cipto Mangunkusumo dengan usia antara 18-60 tahun, tidak mengalami kelainan status gizi, dinilai dengan status fisik ASA 1 atau 2. Kriteria penolakan adalah pasien dengan penyakit diabetes mellitus, kehamilan, distensi abdomen, riwayat dispepsia dan gangguan motilitas usus. Hasil. Pada penelitian ini, didapatkan volume lambung setelah puasa makan padat 6 jam adalah 35,07±39,17 dan setelah puasa 8 jam adalah 14,16±19,24. Selisih antara kedua rerata tersebut adalah 20,91±38,60, p=0,002. Setelah puasa 6 jam, 5.4% subjek memiliki volume lambung di atas 1,5 ml/kg, sedangkan setelah puasa 8 jam, volume lambung seluruh pasien di bawah 1,5 ml/kg. Simpulan. Volume lambung setelah puasa 6 jam lebih kecil secara signifikan dibandingkan dengan puasa 8 jam. ......Background. Preoperative fasting was a common practice to decrease perioperative aspiration risk. Duration of fasting was proportional to gastric volume. Short fasting duration may increase aspiration risk. However, prolonged perioperative fasting duration may lead to dehydration and hypoglycemia. The objective of this study was to analyze gastric volume after 6-hour and 8-hour duration of fasting after consumption of solid meal in patient scheduled for elective surgery. Methods. This was a cohort study for 37 subjects from January to February 2019. Subjects were patient scheduled for elective non-digestive surgery in RSUPN Dr. Cipto Mangunkusumo, with age between 18 to 60 years old, no nutritional status disorder and physical status of ASA 1 or 2. Exclusion criteria were patients with diabetes mellitus, pregnancy, abdominal distention, history of dyspepsia and intestinal motility disturbances. Results. In this study, gastric volume 6-hour after solid intake was 35.07±39.17 and gastric volume 8-hour after solid intake was 14.16±19.24. Difference of gastric volume between 6-hour and 8-hour after solid intake was 20.91±38.60, p=0.002. After 6-hour of fasting, 5.4% of the subjects had gastric volume above 1,5ml/kg, while after 8-hour of fasting, gastric volume of all subjects were below 1,5ml/kg. Conclusion. Gastric volume 8-hour after solid intake was smaller than gastric volume 6-hour after solid intake.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2019
T57633
UI - Tesis Membership  Universitas Indonesia Library
cover
Mochammad Helmi Aziz
Abstrak :
Aerobiologi dari lingkungan rumah sakit merupakan cerminan kebersihan rumah sakit dan berperan dalam penyebaran penyakit infeksi. Berbagai macam kontaminan udara, seperti spora jamur, dapat menyebabkan penyakit pada pasien bila terinhalasi ataupun teringesti, terutama pada populasi pasien imunokompromais. Penelitian ini merupakan penelitian pendahuluan yang bertujuan untuk mengevaluasi jumlah kontaminan jamur udara di dua ruang rawat imunokompromais di Indonesia, RSUPN Dr. Cipto Mangunkusumo. Rerata jumlah koloni di ruang rawat inap hematologi (tanpa filter HEPA) adalah 132 CFU/m3 (76 – 1085 CFU/m3) dan rerata jumlah koloni di ruang rawat intensif dewasa (dengan filter HEPA) adalah 16 CFU/m3 (8 – 42 CFU/m3). Suhu dan kelembapan relatif pernah mencapai ambang batas yang direkomendasikan di kedua ruangan. Ragi, Penicillium spp., dan Aspergillus spp. merupakan tiga kelompok jamur dengan jumlah terbanyak yang berhasil diisolasi dari kedua ruangan. ......Hospital aerobiology is a reflection of hospital cleanliness and has a major role in infectious disease transmission. Several air contaminants, such as fungal spores, can cause disease if inhaled or ingested, especially in immunocompromised patients. This study is a preliminary study that aimed to evaluate the level of fungal airborne contamination in two wards in a referral hospital in Indonesia, RSUPN Dr. Cipto Mangunkusumo. The mean airborne fungal colony count in the hematology ward (without HEPA filter) was 132 CFU/m3 (76 – 1085 CFU/m3) and in the intensive care ward (with HEPA filter) was 16 CFU/m3 (8 – 42 CFU/m3). Temperature and relative humidity were observed above or below the recommended level. Yeast, Penicillium spp., and Aspergillus spp. were three groups of fungi that were mostly isolated from both rooms.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
<<   1 2 3 4 5 6   >>