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It has been investigated the plant of Cinnamomum burmannii Nees exBlume from the West Sumatera as sources of antioxidant and antibacteriacompounds. Extraction with n-hexane and ethanol showed the activities ofantioxidant as radical scavenger and as the antibacteria againt Escherichiacoli. Fractional from the crude extract on silica gel column with the n-hexaneethylacetate solven gradient system for the n-hexane crude extract and theethyl acetate-methanol solven gradient system for the ethanol crude extractyield three fractions. They are examined with radical scavenger method. Then-hexane crude extract and its fraction showed weak of antioxidant capacitybut the ethanol crude extract and the two its fractions showed very powerfulof antioxidant capacity with IC50 9.0 ppm, 7,8 ppm and 11.2 ppm respectively.A Fraction from the n-hexane crude extract (fraction A) and two fractions fromthe ethanol crude extract ( fraction B and fraction C) were analyzed UV, IRand GC-MS. Fraction A consist of trans–cinnamaldehyde (54, 41 %),cinnamate acid (20,49 %), benzaldehyde (7,95 %) danα-phenylacetaldehyde (4,30 %). Fraction B consist of trans–cinnamaldehyde(68,65 %), methyl cinnamate (9,20 %), methyl hexadecanoic (8,49 %) and methyl-9-Octadecenoic (6,99 %). Fraction C consist of ethyl tetradecanoic(43,56 %), ethyl laurate (39,48 %), ethyl hexadecanoic (12,16 %), dioctylhexenedioic (2,98 %) and diisooctyl 1,2-benzenedicarboxylic (1,83 %).Keywords: Antioxidant , Antibacteria activities, Cinnamomum burmanniiNees ex Blume, Escherichia coli, Radical Scavenger . |
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