Dietary food fortified with orotic acid and liver function
Yohanes Buang ([Direktorat Riset dan Pengabdian Masyarakat UI;Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik;Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik, Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik], 2011)
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ABSTRACT The effects of dietary food fortified with orotic acid (1.0%)on liver function were studied in rats. The rats fed with orotic acid promoted liver triglyceride content markedly, that was 5-fold higher than that of the control. The liver malondialdehyde (MDA) content increased by 10%, but the gluthation peroxidase (GSH-Px) activity decreased by 50%. The serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities increased by 25% and 30%,respectively. Therefore, the decreased GSH-Px activity was associated with the promotions of AST, ALT, and the liver MDA levels. In conclusion: dietary orotic acid promotes lipid peroxidation but reduces the rate of the antioxidant enzyme. Therefore, dietary food fortified with orotic acid attenuates the liver function. |
No. Panggil : | J-Pdf |
Entri utama-Nama orang : | |
Subjek : | |
Penerbitan : | [Place of publication not identified]: [Direktorat Riset dan Pengabdian Masyarakat UI;Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik;Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik, Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik], 2011 |
Sumber Pengatalogan : | LibUI eng rda |
ISSN : | 23391995 |
Majalah/Jurnal : | Makara : Sains |
Volume : | Vol. 15, No. 2, November 2011: 101-105 |
Tipe Konten : | text |
Tipe Media : | unmediated |
Tipe Carrier : | volume |
Akses Elektronik : | http://journal.ui.ac.id/index.php/science/article/view/1057/970 |
Institusi Pemilik : | Universitas Indonesia |
Lokasi : | Direktorat Riset dan Pengabdian Masyarakat UI |
No. Panggil | No. Barkod | Ketersediaan |
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J-Pdf | 03-19-181039563 | TERSEDIA |
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