:: Artikel Jurnal :: Kembali

Artikel Jurnal :: Kembali

Synthesizing derivatives from cyclopentanone analogue curcumin and their toxic, antioxidant and anti-inflammatory activities

Yum Eryanti, Yuana Nurulita, Rudi Hendra, Yuharmen, Jufrizal Syahri, Adel Zamri ([Direktorat Riset dan Pengabdian Masyarakat UI;Universitas Riau. Departemen Kimia;Universitas Riau. Departemen Kimia, Universitas Riau. Departemen Kimia], 2011)

 Abstrak

ABSTRACT
Three types of cyclopentanone derivatives have been synthesized from aromatic aldehyde and ketone derivatives under
a base condition through aldol condensation. These cyclopentanone products were 2,5-dibenzylidene-cyclopentanone (a), 2,5-bis-(4-hydroxy-benzylidene)-cyclopentanone (b),
and 2,5-bis-(4-hydroxy-benzylidene)-cyclopentanone (c)
which has a yield of 63-99%. The chemical structure of these compounds were determined using UV, IR and NMR
spectroscopy. In order to clarify the role of hydroxyl and amine moieties, toxic, antioxidant and anti-inflammatory
activities were carried out. The toxic test indicated that the
compounds showed strong toxicity. In addition, the presence
of hydroxyl and amine groups on both rings of curcumin in
creased the antioxidant and anti-inflammatory activities.

 Metadata

No. Panggil : J-Pdf
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Subjek :
Penerbitan : [Place of publication not identified]: [Direktorat Riset dan Pengabdian Masyarakat UI;Universitas Riau. Departemen Kimia;Universitas Riau. Departemen Kimia, Universitas Riau. Departemen Kimia], 2011
Sumber Pengatalogan : LibUI eng rda
ISSN : 23391995
Majalah/Jurnal : Makara : Sains
Volume : Vol. 15, No. 2, November 2011: 117-123
Tipe Konten : text
Tipe Media : unmediated
Tipe Carrier : volume
Akses Elektronik : http://journal.ui.ac.id/index.php/science/article/view/1060/973
Institusi Pemilik : Universitas Indonesia
Lokasi : Direktorat Riset dan Pengabdian Masyarakat UI
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No. Panggil No. Barkod Ketersediaan
J-Pdf 03-19-936697566 TERSEDIA
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