The effects of dietary food fortified with vitamin B4 on lipid profiles in serum and liver tissue / Yohanes Buang
Yohanes Buang;
([Direktorat Riset dan Pengabdian Masyarakat UI;Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik;Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik, Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik], 2010)
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| The effects of dietary food fortified with vitamin B4 on lipid profiles in serum and liver tissue were studied. Rats were paired-fed a 0.25% vitamin B4 diet or a diet without vitamin B4 for 10 days. Serum lipid levels were measured using enzyme assay kits. Lipids of liver tissues were extracted and the lipid contents were determined. A piece of liver was prepared to determine the activities of fatty acid synthase (FAS) and fatty acid β-oxidation. The results showed that animals fed a food fortified with vitamin B4 had higher level of serum TG, PL, total cholesterol, and high density lipoprotein. Their increases were approximately by 74%, 20%, 27%, and 27%, respectively. The significant changes in liver lipid were only found in PL component. This treatment promoted FAS activity, but impaired the fatty acid β-oxidation. In conclusion: Dietary food fortified with vitamin B4 induces hypertriglyceridemia and liver PL level. |
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| Penerbitan : | [Place of publication not identified]: [Direktorat Riset dan Pengabdian Masyarakat UI;Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik;Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik, Universitas Nusa Cendana - Kupang. Fakultas Sains dan Teknik], 2010 |
| Sumber Pengatalogan : | LibUI eng rda |
| ISSN : | 23563656 |
| Majalah/Jurnal : | Makara Journal of Health Research |
| Volume : | Vol. 14, No. 1, Juni 2010: Hal. : 1-4 |
| Tipe Konten : | text |
| Tipe Media : | computer |
| Tipe Carrier : | online resource |
| Akses Elektronik : | http://journal.ui.ac.id/index.php/health/article/view/639/624 |
| Institusi Pemilik : | Universitas Indonesia |
| Lokasi : | Direktorat Riset dan Pengabdian Masyarakat UI |
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