[Tujuan: Menentukan hubungan antara volume lemak perikardial dengan derajatstenosis aterosklerosis arteri koronaria pada pasien yang menjalani pemeriksaandual-source CT jantung di RSCM, sehingga dapat dilakukan penentuan titikpotong volume lemak perikardial yang dapat digunakan untuk mendeteksi derajatstenosis aterosklerosis arteri koronaria hanya dengan menghitung volume lemakperikardial saja.Metode: Analisa retrospektif hasil CT jantung dari 53 pasien yang diambil secaraconsecutive, meliputi penilaian derajat stenosis aterosklerosis arteri koronaria danpenghitungan volume lemak perikardial. Derajat stenosis aterosklerosis arterikoronaria dikelompokkan menjadi tidak ada stenosis, ringan, sedang dan berat,berdasarkan metode indeks prognosis Duke. Volume lemak perikardial dihitungdalam satuan cm3 dengan menggunakan perangkat lunak analisa volume padacardiac workstation (Siemens, Leonardo), lemak perikardial adalah gabunganantara lemak epikardial dengan lemak parakardial. Analisa statistik penelitian inimenggunakan uji Anova.Hasil: Terdapat hubungan positif antara volume lemak perikardial denganstenosis arteri koronaria derajat sedang pada pasien di RSCM yang menjalanipemeriksaan DSCT jantung. Titik potong volume lemak perikardial untukmendeteksi stenosis arteri koronaria derajat sedang adalah 185 cm3 (≥ 185 cm3dan < 185 cm3), dengan nilai sensitifitas 81,8 %, spesifisitas 63,15 %, akurasi 70% dan OR 7,71 pada 95 % interval kepercayaan 1,03 – 72,06.Kesimpulan: Volume lemak perikardial dapat digunakan untuk menentukanstenosis arteri koronaria derajat sedang, sehingga dapat dipakai sebagai suatuacuan deteksi dini stenosis arteri koronaria bagi pasien yang beresiko terhadapkejadian PJK.;Purpose: to determine the correlation between pericardial fat volume and stenosisgrade of atherosclerotic coronary artery in patients who underwent dual-sourcecardiac CT in Cipto Mangunkusumo hospital and cut off point of pericardial fatvolume that can be used to determine stenosis grade of atherosclerotic coronaryartery.Methods : Retrospective analysis of 53 consecutive patients who underwent dualsourcecardiac CT in Cipto Mangunkusumo hospital, the assessment was includestenosis grade of atherosclerotic coronary artery and pericardial fat volume.Stenosis grade were classified as no stenosis, mild, moderate and severe based onprognostic index Duke. Pericardial fat volume was measured in cm3 using theVolume Analysis software tool of our cardiac workstation (Siemens, Leonardo),pericardial fat defined as epicardial fat plus paracardial fat. Statisticall analysiswere performed with Anova test.Results : There was positive correlation between pericardial fat volume andmoderate stenosis of atherosclerotic coronary artery in patients who underwentdual-source cardiac CT in Cipto Mangunkusumo hospital. A cut-off value of 185cm3 (≥ 185 cm3 and <185 cm3) determined a sensitivity and specivicity to detectmoderate stenosis of 81,8% and 63,15%,, with accuracy of 70% and OR 7,71 in95% confident interval 1,03 – 72,06.Conclusions : Pericardial fat volume can be use to determine moderate stenosis ofatherosclerotic coronary artery in patients who underwent dual-source cardiac CTin Cipto Mangunkusumo hospital due to early detection for coronary stenoticcondition in patient who have higher risk for CAD., Purpose: to determine the correlation between pericardial fat volume and stenosisgrade of atherosclerotic coronary artery in patients who underwent dual-sourcecardiac CT in Cipto Mangunkusumo hospital and cut off point of pericardial fatvolume that can be used to determine stenosis grade of atherosclerotic coronaryartery.Methods : Retrospective analysis of 53 consecutive patients who underwent dualsourcecardiac CT in Cipto Mangunkusumo hospital, the assessment was includestenosis grade of atherosclerotic coronary artery and pericardial fat volume.Stenosis grade were classified as no stenosis, mild, moderate and severe based onprognostic index Duke. Pericardial fat volume was measured in cm3 using theVolume Analysis software tool of our cardiac workstation (Siemens, Leonardo),pericardial fat defined as epicardial fat plus paracardial fat. Statisticall analysiswere performed with Anova test.Results : There was positive correlation between pericardial fat volume andmoderate stenosis of atherosclerotic coronary artery in patients who underwentdual-source cardiac CT in Cipto Mangunkusumo hospital. A cut-off value of 185cm3 (≥ 185 cm3 and <185 cm3) determined a sensitivity and specivicity to detectmoderate stenosis of 81,8% and 63,15%,, with accuracy of 70% and OR 7,71 in95% confident interval 1,03 – 72,06.Conclusions : Pericardial fat volume can be use to determine moderate stenosis ofatherosclerotic coronary artery in patients who underwent dual-source cardiac CTin Cipto Mangunkusumo hospital due to early detection for coronary stenoticcondition in patient who have higher risk for CAD.] |