:: UI - Tesis Membership :: Kembali

UI - Tesis Membership :: Kembali

Model prediksi infeksi rotavirus pada anak balita dengan diare akut berdasarkan gejala klinis dan karakteristik lainnya di Rumah Sakit Umum Serang tahun 2012 = Prediction model of rotavirus infection among children under five with acute diarrhea based on clinical symptoms and other characteristic in Serang Hospital 2012

Sinta Purnamawati; Pandu Riono, supervisor; Besral, supervisor; Irawan Mangunatmadja, supervisor; Vivi Setiawaty, examiner (Fakultas Kesehatan Masyarakat Universitas Indonesia, 2014)

 Abstrak

[ABSTRAK
Latar Belakang. Rotavirus merupakan penyebab terbesar dari penyakit diare akut
pada anak balita. Gejala klinis yang ditimbulkan yaitu diare, demam, muntah,
nyeri perut, dan dehidrasi. Berdasarkan hasil penelitian di dua kota tahun 2007,
ditemukan 47% Rotavirus sebagai penyebab diare akut di RS Hasan Sadikin,
Bandung, sedangkan di RS Dr Sardjito, Yogyakarta ditemukan 32%. Biaya
pemeriksaan laboratorium untuk mendeteksi adanya Rotavirus sangat mahal pada
laboratorium tertentu saja. Belum diketahui kemampuan mendeteksi diare yang
disebabkan Rotavirus berdasarkan beberapa gejala klinis dan karakteristik anak
balita dengan diare akut.
Objektif. Mengeksplorasi model prediksi untuk diagnosis diare yang disebabkan
infeksi Rotavirus pada anak balita dengan diare akut dengan berdasarkan
informasi gejala klinis dan karakteristik anak.
Metode. Analisis dilakukan dengan menggunakan subsampel data penelitian
utama Badan Penelitian dan Pengembangan Kesehatan Kementrian Kesehatan RI
yang berjudul ?Identifikasi dan Uji Resistensi Mikroorganisme Penyebab Diare
Pada Anak Balita di Indonesia tahun 2011?. Data anak balita dengan diare yang
dirawat di Rumah Sakit Umum Serang selama tahun 2012 dikumpulkan melalui
kuesioner. Selain gejala klinis dan karakteristik anak, dikumpulkan juga sampel
tinja untuk dilakukan pemeriksaan adanya Rotavirus dengan metode Real-Time
PCR..
Hasil. Hasil penelitian menunjukkan bahwa gejala demam, kondisi tinja cair dan
karakteristik anak (meliputi umur balita dan tidak diberi ASI) dapat digunakan
untuk memprediksi adanya infeksi Rotavirus pada anak balita dengan diare akut.
Model prediksi untuk nilai duga positif terjadinya infeksi Rotavirus pada anak
diare akut sebesar 71,43%, berdasarkan gejala klinis (meliputi demam dan
kondisi tinja cair) dan karakteristik anak (umur balita dan tidak diberi ASI). Pada
anak diare akut yang mengalami gejala demam, kondisi tinja cair, umur 1-12
bulan, dan tidak diberi ASI, dugaan penyebab diare akut adalah rotavirus dengan
peluang sebesar 82,1%.
Simpulan dan Saran. Karakteristik anak dan beberapa gejala klinis dapat
digunakan untuk menduga penyebab diare akut yang disebabkan Rotavirus.
Mendasari hasil penelitian disarankan agar anak diare yang diikuti dengan
demam dan kondisi tinja cair, perlu mendapat penanganan segera dengan diawali
rehidrasi dan dapat dijadikan masukan bagi kebijakan dalam tatalaksana diare
akut yang disebabkan Rotavirus.

ABSTRACT
Background. Rotavirus is the common cause of acute diarrheal disease in
children under five years old with the several clinical symptoms such as watery
stool, fever, vomiting, abdominal pain and dehydration. Based on the previous
studies, the prevalence rotavirus among underfive children between 32% and 47%
at two hospital in the two cities in the year 2007. Laboratory cost for examining
Rotavirus is very expensive. Until now, we don?t know how accurate to predict
Rotavirus as a cause of acute diarrhea among underfive children based on the
information of clinical symptoms and children?s characteristics.
Objectives. The aim of this study is to explore the prediction model for
diagnosing Rotavirus diarrhea among underfive children by clinical symptoms
and other characteristics.
Methods. Using data from the main study of ?Identification and resistance
analysis of microorganism causing diarrhea among children under five years old
in Indonesia? was analyzed?. The study collected data from the questionnaire and
also specimens in Serang Hospital in 2012. The analyses were completed by
laboratory data from the specimens by Real-Time PCR.
Results: The results of the study found that fever, watery stools and age under 12
months without having breastfeeding can be used as prediction model of
Rotavirus infections among children with acute diarrhea. The prediction model of
positive predictive value of Rotavirus infection of acute diarrhea is 71,43%. The
positive predictive value is fulfilled from clinical symptoms including fever and
watery stools and toddlers without having breastfeeding. Children presenting
acute diarrhea with fever, watery stools, age under 12 months and no breast
feeding had the prediction value 82,1%.
Conclusion and recommendation. Characteristics and clinical symptoms of
children underfive might be used to predict diarrhea caused by Rotavirus.
Rehydration of acute diarrhea of Rotavirus infection is important step in
management of acute diarrhea among underfive children.;Background. Rotavirus is the common cause of acute diarrheal disease in
children under five years old with the several clinical symptoms such as watery
stool, fever, vomiting, abdominal pain and dehydration. Based on the previous
studies, the prevalence rotavirus among underfive children between 32% and 47%
at two hospital in the two cities in the year 2007. Laboratory cost for examining
Rotavirus is very expensive. Until now, we don’t know how accurate to predict
Rotavirus as a cause of acute diarrhea among underfive children based on the
information of clinical symptoms and children’s characteristics.
Objectives. The aim of this study is to explore the prediction model for
diagnosing Rotavirus diarrhea among underfive children by clinical symptoms
and other characteristics.
Methods. Using data from the main study of “Identification and resistance
analysis of microorganism causing diarrhea among children under five years old
in Indonesia” was analyzed”. The study collected data from the questionnaire and
also specimens in Serang Hospital in 2012. The analyses were completed by
laboratory data from the specimens by Real-Time PCR.
Results: The results of the study found that fever, watery stools and age under 12
months without having breastfeeding can be used as prediction model of
Rotavirus infections among children with acute diarrhea. The prediction model of
positive predictive value of Rotavirus infection of acute diarrhea is 71,43%. The
positive predictive value is fulfilled from clinical symptoms including fever and
watery stools and toddlers without having breastfeeding. Children presenting
acute diarrhea with fever, watery stools, age under 12 months and no breast
feeding had the prediction value 82,1%.
Conclusion and recommendation. Characteristics and clinical symptoms of
children underfive might be used to predict diarrhea caused by Rotavirus.
Rehydration of acute diarrhea of Rotavirus infection is important step in
management of acute diarrhea among underfive children., Background. Rotavirus is the common cause of acute diarrheal disease in
children under five years old with the several clinical symptoms such as watery
stool, fever, vomiting, abdominal pain and dehydration. Based on the previous
studies, the prevalence rotavirus among underfive children between 32% and 47%
at two hospital in the two cities in the year 2007. Laboratory cost for examining
Rotavirus is very expensive. Until now, we don’t know how accurate to predict
Rotavirus as a cause of acute diarrhea among underfive children based on the
information of clinical symptoms and children’s characteristics.
Objectives. The aim of this study is to explore the prediction model for
diagnosing Rotavirus diarrhea among underfive children by clinical symptoms
and other characteristics.
Methods. Using data from the main study of “Identification and resistance
analysis of microorganism causing diarrhea among children under five years old
in Indonesia” was analyzed”. The study collected data from the questionnaire and
also specimens in Serang Hospital in 2012. The analyses were completed by
laboratory data from the specimens by Real-Time PCR.
Results: The results of the study found that fever, watery stools and age under 12
months without having breastfeeding can be used as prediction model of
Rotavirus infections among children with acute diarrhea. The prediction model of
positive predictive value of Rotavirus infection of acute diarrhea is 71,43%. The
positive predictive value is fulfilled from clinical symptoms including fever and
watery stools and toddlers without having breastfeeding. Children presenting
acute diarrhea with fever, watery stools, age under 12 months and no breast
feeding had the prediction value 82,1%.
Conclusion and recommendation. Characteristics and clinical symptoms of
children underfive might be used to predict diarrhea caused by Rotavirus.
Rehydration of acute diarrhea of Rotavirus infection is important step in
management of acute diarrhea among underfive children.]

 File Digital: 1

Shelf
 T42303-Sinta Purnamawati.pdf :: Unduh

LOGIN required

 Metadata

No. Panggil : T42303
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Entri tambahan-Nama badan :
Subjek :
Penerbitan : Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2014
Program Studi :
Bahasa : ind
Sumber Pengatalogan : LibUI ind rda
Tipe Konten : text
Tipe Media : unmediated ; computer
Tipe Carrier : volume ; online resource
Deskripsi Fisik : xii, 71 pages : ill ; 28 cm + appendix
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, lantai 3
  • Ketersediaan
  • Ulasan
No. Panggil No. Barkod Ketersediaan
T42303 15-17-504444416 TERSEDIA
Ulasan:
Tidak ada ulasan pada koleksi ini: 20388999