Perbedaan kadar c-reactive protein pada demam akut karena infeksi dengue dengan demam tifoid = Differences in the levels of crp in the acute febrile cause of dengue infection or typhoid fever
Adeputri Tanesha Idhayu;
Khie Chen, supervisor
(Fakultas Kedokteran Universitas Indonesia, 2014)
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[ABSTRAK Latar Belakang Infeksi dengue dan demam tifoid merupakan penyakit endemik di Indonesia Namun pada awal awitan demam terdapat kesulitan dalam membedakan keduanya Oleh karena itu dibutuhkan modalitas pemeriksaan penunjang yang sederhana untuk membantu diagnosis infeksi dengue dan demam tifoid C Reactive Protein CRP merupakan alat bantu diagnostik yang terjangkau cepat dan murah untuk diagnosis penyebab demam akut Penelitian ini bertujuan mengetahui perbedaan kadar CRP pada demam akut karena infeksi dengue dengan demam tifoid Metode Penelitian ini merupakan studi potong lintang pada pasien demam akut dengan diagnosis demam dengue demam berdarah dengue atau demam tifoid yang dirawat di IGD atau ruang rawat RSCM RS Pluit dan RS Metropolitan Medical Center Jakarta dalam kurun waktu Januari 2010 sampai dengan Desember 2013 Kadar CRP yg diteliti adalah CRP yang diperiksa 2 5 hari setelah awitan demam Data penyerta yang dikumpulkan adalah data demografis data klinis pemberian antibiotik selama perawatan leukosit trombosit netrofil LED dan lama perawatan Hasil Sebanyak 188 subjek diikutsertakan pada penelitian ini terdiri dari 102 pasien dengue dan 86 pasien demam tifoid Didapatkan median RIK CRP pada infeksi dengue adalah 11 65 16 mg L dan pada demam tifoid adalah 53 75 mg L Terdapat perbedaan median CRP yang bermakna antara infeksi dengue dan demam tifoid p 45 91 mg L merupakan diagnostik CRP untuk demam tifoid kadar CRP ABSTRACT Background Dengue infection and typhoid fever are endemic disease in Indonesia But in the early days of onset sometimes it is difficult to distinguish them A simple modality test is needed to support the diagnosis C Reactive Protein CRP is an affordable fast and relatively less expensive diagnostic tool to diagnose the causes of acute fever This study was aimed to determine the differences of CRP level in the acute febrile caused by dengue infection or typhoid fever Methods A cross sectional study has been conducted among acute febrile patients with diagnosis of dengue fever dengue hemorrhagic fever or typhoid fever who admitted to the emergency room or hospitalized in Cipto Mangunkusumo Hospital Pluit Hospital and Metropolitan Medical Center Hospital Jakarta between January 2010 and December 2013 Data obtained from medical records CRP used in this study was examined at 2 5 days after onset of fever The other collected data were demographic data clinical data use of antibiotics leukocytes platelets neutrophils ESR and length of stay in hospital Results 188 subjects met the inclusion criteria 102 patients with dengue and 86 patients with typhoid fever Median CRP levels in dengue infection was 11 65 16 mg L and in typhoid fever was 53 75 mg L There were significant differences in median CRP levels between dengue infection and typhoid fever p 0 001 At the 99 percentile cut off point CRP levels for dengue infection was 45 91 mg L and CRP levels for typhoid fever at 1 percentile was 8 mg L Conclusion There was significantly different levels of CRP in acute fever due to dengue infection and typhoid fever At the 99 percentile cut off point CRP level 45 91 mg L was diagnostic for typhoid fever CRP level , Background Dengue infection and typhoid fever are endemic disease in Indonesia But in the early days of onset sometimes it is difficult to distinguish them A simple modality test is needed to support the diagnosis C Reactive Protein CRP is an affordable fast and relatively less expensive diagnostic tool to diagnose the causes of acute fever This study was aimed to determine the differences of CRP level in the acute febrile caused by dengue infection or typhoid fever Methods A cross sectional study has been conducted among acute febrile patients with diagnosis of dengue fever dengue hemorrhagic fever or typhoid fever who admitted to the emergency room or hospitalized in Cipto Mangunkusumo Hospital Pluit Hospital and Metropolitan Medical Center Hospital Jakarta between January 2010 and December 2013 Data obtained from medical records CRP used in this study was examined at 2 5 days after onset of fever The other collected data were demographic data clinical data use of antibiotics leukocytes platelets neutrophils ESR and length of stay in hospital Results 188 subjects met the inclusion criteria 102 patients with dengue and 86 patients with typhoid fever Median CRP levels in dengue infection was 11 65 16 mg L and in typhoid fever was 53 75 mg L There were significant differences in median CRP levels between dengue infection and typhoid fever p 0 001 At the 99 percentile cut off point CRP levels for dengue infection was 45 91 mg L and CRP levels for typhoid fever at 1 percentile was 8 mg L Conclusion There was significantly different levels of CRP in acute fever due to dengue infection and typhoid fever At the 99 percentile cut off point CRP level 45 91 mg L was diagnostic for typhoid fever CRP level ] |
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| No. Panggil : | SP-pdf |
| Entri utama-Nama orang : | |
| Entri tambahan-Nama orang : | |
| Entri tambahan-Nama badan : | |
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| Penerbitan : | [Place of publication not identified]: Fakultas Kedokteran Universitas Indonesia, 2014 |
| Program Studi : |
| Bahasa : | 16-17-855727753 |
| Sumber Pengatalogan : | LibUI ind rda |
| Tipe Konten : | text |
| Tipe Media : | computer |
| Tipe Carrier : | online resource |
| Deskripsi Fisik : | xvi, 65 pages + appendix |
| Naskah Ringkas : | |
| Lembaga Pemilik : | Universitas Indonesia |
| Lokasi : | Perpustakaan UI, Lantai 3 |
| No. Panggil | No. Barkod | Ketersediaan |
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| SP-pdf | TERSEDIA |
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