Label-free technologies for drug discovery
Matthew Cooper (John Wiley and Sons, 2011)
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| Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories. Label-free technologies for drug discovery summarises the latest and emerging developments in label-free detection systems, their underlying technology principles and end-user case studies that reveal the power and limitations of label-free in all areas of drug discovery.Label-free technologies discussed include SPR, NMR, high-throughput mass spectrometry, resonant waveguide plate-based screening, transmitted-light imaging, isothermal titration calorimetry, optical and impedance cell-based assays and other biophysical methods. The technologies are discussed in relation to their use as screening technologies, high-content technologies, hit finding and hit validation strategies, mode of action and ADME/T, access to difficult target classes, cell-based receptor/ligand interactions particularly orphan receptors, and antibody and small molecule affinity and kinetic analysis.Label-Free Technologies For Drug Discovery is an essential guide to this emerging class of tools for researchers in drug discovery and development, particularly high-throughput screening and compound profiling teams, medicinal chemists, structural biologists, assay developers, ADME/T specialists, and others interested in biomolecular interaction analysis. |
 Label-Free Technologies For Drug Discovery-Fulltexts.pdf :: Unduh
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| No. Panggil : | e20394205 |
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| Penerbitan : | Chichester: John Wiley and Sons, 2011 |
| Sumber Pengatalogan: | LibUI eng rda |
| Tipe Konten: | text |
| Tipe Media: | computer |
| Tipe Pembawa: | online resource |
| Deskripsi Fisik: | |
| Tautan: | http://onlinelibrary.wiley.com/book/10.1002/9780470979129 |
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| No. Panggil | No. Barkod | Ketersediaan |
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| e20394205 | TERSEDIA |
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| Tidak ada ulasan pada koleksi ini: 20394205 |
