Pharmacophores and pharmacophore searches
edited by Thierry Langer and Remy D. Hoffmann (Wiley-VCH, 2006)
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This handbook is the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research.Starting with an introductory historical overview, the authors move on to discuss ligand-based approaches, including 3D pharmacophores and 4D QSAR, as well as the concept and application of pseudoreceptors. The next section on structure-based approaches includes pharmcophores from ligand-protein complexes, FLIP and 3D protein-ligand binding interactions. The whole is rounded off with a complete section devoted to applications and examples, including modeling of ADME properties. |
Pharmacophores and Pharmacophore Searches-Fulltexts.pdf :: Unduh
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No. Panggil | No. Barkod | Ketersediaan |
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e20395917 | 20-24-30126744 | TERSEDIA |
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