Caveolins and caveolae: roles in signaling and disease mechanisms
edited by Jean-François Jasmin, Philippe G. Frank, Michael P. Lisanti (Springer, 2012)
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| Caveolae are 50-100 nm flask-shaped invaginations of the plasma membrane that are primarily composed of cholesterol and sphingolipids. Using modern electron microscopy techniques, caveolae can be observed as omega-shaped invaginations of the plasma membrane, fully-invaginated caveolae, grape-like clusters of interconnected caveolae (caveosome), or as transcellular channels as a consequence of the fusion of individual caveolae. The caveolin gene family consists of three distinct members, namely Cav-1, Cav-2 and Cav-3. Cav-1 and Cav-2 proteins are usually co-expressed and particularly abundant in epithelial, endothelial, and smooth muscle cells as well as adipocytes and fibroblasts. On the other hand, the Cav-3 protein appears to be muscle-specific and is therefore only expressed in smooth, skeletal and cardiac muscles. Caveolin proteins form high molecular weight homo- and/or hetero-oligomers and assume an unusual topology with both their N- and C-terminal domains facing the cytoplasm. |
 Caveolins and Caveolae.pdf :: Unduh
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| No. Panggil : | e20401435 |
| Entri tambahan-Nama orang : | |
| Subjek : | |
| Penerbitan : | New York: Springer, 2012 |
| Sumber Pengatalogan: | LibUI eng rda |
| Tipe Konten: | text |
| Tipe Media: | computer |
| Tipe Pembawa: | online resource |
| Deskripsi Fisik: | |
| Tautan: | http://link.springer.com/book/10.1007%2F978-1-4614-1222-9 |
| Lembaga Pemilik: | |
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| No. Panggil | No. Barkod | Ketersediaan |
|---|---|---|
| e20401435 | 20-22-34405233 | TERSEDIA |
| Ulasan: |
| Tidak ada ulasan pada koleksi ini: 20401435 |
