Deskripsi Lengkap
| Bahasa : | ind |
| Sumber Pengatalogan : | LibUI ita rda |
| Tipe Konten : | text (rdacontent) |
| Tipe Media : | unmediated (rdamedia) ; computer (rdamedia) |
| Tipe Carrier : | volume (rdacarrier) ; online resource (rdacarrier) |
| Deskripsi Fisik : | xv, 41 pages : illustration ; 28 cm + appendix |
| Naskah Ringkas : | |
| Lembaga Pemilik : | Universitas Indonesia |
| Lokasi : | Perpustakaan UI, Lantai 3 |
- Ketersediaan
- File Digital: 1
- Ulasan
- Sampul
- Abstrak
| No. Panggil | No. Barkod | Ketersediaan |
|---|---|---|
| S-Pdf | TERSEDIA |
| Tidak ada ulasan pada koleksi ini: 20402129 |
Abstrak
ABSTRAK
Latar Belakang: Rosela mempunyai efek anti-inflamasi yang mempercepat proses penyembuhan. Fibroblas berperan penting dalam proses penyembuhan. Tujuan: Mengevaluasi hasil proses penyembuhan ulser mukosa mulut tikus berdasarkan ekspresi fibroblas secara imunohistokimia pascapaparan ekstrak etanol rosela 15%. Metode: Sampel ulser mukosa mulut tikus pascapaparan kelompok kontrol dan kelompok perlakuan diwarnai dengan antibodi TE-7(immunohistokimia). Parameter yang digunakan sel positif dan intensitas warna (pixel). Hasil: Terdapat peningkatan sel positif pada kelompok rosela 15% dihari ke-3 (skor 2) dengan intensitas warna menunjukan skor kuat (<125 pixel) pada hari ke-1, -3, -7, -14. Kesimpulan: Terdapat peningkatan ekspresi fibroblas pada proses penyembuhan ulser mukosa mulut tikus pascapaparan ekstrak etanol rosella 15%.
ABSTRACT
Backgrounds:Roselle have an anti-inflammatory effect that can accelerate wound healing. Fibroblast play a critical role in wound healing process. Objectives: To evaluate the result of wound healing process towards rat oral mucous ulcer based on fibroblast expression in immunohistochemistry after exposure 15% ethanol roselle extract. Methods: rat oral mucous ulcer samples after exposure the control group and the treatment group that stained by TE-7 antibody (immunohistochemistry). Parameters that used are positive cells and color intensity (pixels). Results: There was an increase of positive cells in group 15% roselle on the 3rd day (score 2) with color intensity indicates high score (<125 pixels) from the 1st, 3rd, 7th and 14th days. Conclusions: Fibroblast expression increased in wound healing process of rat oral mucous ulcer after exposure 15% ethanol roselle extract
Latar Belakang: Rosela mempunyai efek anti-inflamasi yang mempercepat proses penyembuhan. Fibroblas berperan penting dalam proses penyembuhan. Tujuan: Mengevaluasi hasil proses penyembuhan ulser mukosa mulut tikus berdasarkan ekspresi fibroblas secara imunohistokimia pascapaparan ekstrak etanol rosela 15%. Metode: Sampel ulser mukosa mulut tikus pascapaparan kelompok kontrol dan kelompok perlakuan diwarnai dengan antibodi TE-7(immunohistokimia). Parameter yang digunakan sel positif dan intensitas warna (pixel). Hasil: Terdapat peningkatan sel positif pada kelompok rosela 15% dihari ke-3 (skor 2) dengan intensitas warna menunjukan skor kuat (<125 pixel) pada hari ke-1, -3, -7, -14. Kesimpulan: Terdapat peningkatan ekspresi fibroblas pada proses penyembuhan ulser mukosa mulut tikus pascapaparan ekstrak etanol rosella 15%.
ABSTRACT
Backgrounds:Roselle have an anti-inflammatory effect that can accelerate wound healing. Fibroblast play a critical role in wound healing process. Objectives: To evaluate the result of wound healing process towards rat oral mucous ulcer based on fibroblast expression in immunohistochemistry after exposure 15% ethanol roselle extract. Methods: rat oral mucous ulcer samples after exposure the control group and the treatment group that stained by TE-7 antibody (immunohistochemistry). Parameters that used are positive cells and color intensity (pixels). Results: There was an increase of positive cells in group 15% roselle on the 3rd day (score 2) with color intensity indicates high score (<125 pixels) from the 1st, 3rd, 7th and 14th days. Conclusions: Fibroblast expression increased in wound healing process of rat oral mucous ulcer after exposure 15% ethanol roselle extract