[ABSTRAK
Suplemen besi yang mengandung ferrous sulfat umum digunakan untuk antianemia. Sediaan ini memiliki rasa tidak enak, menyebabkan mual dan jikadigunakan dengan dosis besar dan jangka waktu lama dapat menyebabkan efeksamping. Perlu dicari alternative sumber lain, termasuk dari tanaman. DaunMoringa pterigospera Gaertn dipilih karena mengandung besi dan suplemen lain.Penelitian ini bertujuan untuk membuat formulasi serbuk instan untuk anti anemiasebagai alternatif suplementasi zat besi selain dari ferous sulfat, denganmenggunakan ekstrak dari daun kelor (Moringa pterigosperma Gaertn). Ekstrakdiperoleh dengan metode Microwave Assisted Extraction. Optimasi kondisidibuat dengan memvariasikan pelarut etanol (0-70%), daya listrik microwave(450-900 watt) dan waktu ekstraksi 3-10 menit. Analisa kadar besi dilakukanmenggunakan Spektrofotometer Serapan Atom pada panjang gelombang 248 nm.Formula serbuk instan dibuat dengan 3 konsentrasi natrium CMC sebagai bahanpensuspensi. Penelitian menunjukkan bahwa kondisi optimal ekstraksi yangmenghasilkan kandungan besi paling besar (2,4 mg/g ekstrak) dicapai dengandaya listrik 900 watt, waktu ekstraksi 10 menit dan pelarut air suling. Berdasarkanuji hedonis dengan 30 panelis, formula dengan 5% natrium CMC paling disukai.Bentuk serbuk memiliki kadar air 2,31%, laju alir 7,74 g/detik dan bentukrekonstitusinya memiliki pH 5,78, dan viskositas 15,98 cps.
ABSTRACT
Iron supplement contains ferrous sulfate is commonly used for anemia. Ferroussulfate has bad taste, can cause nausea, and made adverse effects if taken in largedoses for long periods. It is necessary to find an alternative source of rawmaterials, including those from plants. Moringa pterigospera Gaertn leaves wasselected because it contains iron and other nutritions. The purpose of this workwas to make instant powder formula for anti anemia using Moringa leave?s extractas an alternative for ferous suphate iron suplementation. The extraction wasperformed by Microwave Assisted Extraction method. Optimation of extractioncondition was performed by creating some variations in solvent composition (0-70% ethanol), microwave power (450 to 900 watts) and extraction time (3 to 10min). Iron content was determined by Atomic Absorption Spectrophotometer atwavelength of 248 nm. Instant powder formula was made in 3 concentrations ofsodium CMC as suspending agent. Results of the study showed that the mostoptimal extraction condition which resulted the highest iron content (2.4 mgiron/g extracts) achieved with 900 watts microwave power, 10 min extraction timeand aquademineralisata. According to 30 panelists of hedonic test, formula whichused 5% w/w of sodium CMC got the highest scores. Its powder form had 2.31%of loss on drying and 7.74 g/sec of flow rate for powder form and pH of 5.78,viscosity of 15.98 cps for reconstituted form.;Iron supplement contains ferrous sulfate is commonly used for anemia. Ferroussulfate has bad taste, can cause nausea, and made adverse effects if taken in largedoses for long periods. It is necessary to find an alternative source of rawmaterials, including those from plants. Moringa pterigospera Gaertn leaves wasselected because it contains iron and other nutritions. The purpose of this workwas to make instant powder formula for anti anemia using Moringa leave’s extractas an alternative for ferous suphate iron suplementation. The extraction wasperformed by Microwave Assisted Extraction method. Optimation of extractioncondition was performed by creating some variations in solvent composition (0-70% ethanol), microwave power (450 to 900 watts) and extraction time (3 to 10min). Iron content was determined by Atomic Absorption Spectrophotometer atwavelength of 248 nm. Instant powder formula was made in 3 concentrations ofsodium CMC as suspending agent. Results of the study showed that the mostoptimal extraction condition which resulted the highest iron content (2.4 mgiron/g extracts) achieved with 900 watts microwave power, 10 min extraction timeand aquademineralisata. According to 30 panelists of hedonic test, formula whichused 5% w/w of sodium CMC got the highest scores. Its powder form had 2.31%of loss on drying and 7.74 g/sec of flow rate for powder form and pH of 5.78,viscosity of 15.98 cps for reconstituted form., Iron supplement contains ferrous sulfate is commonly used for anemia. Ferroussulfate has bad taste, can cause nausea, and made adverse effects if taken in largedoses for long periods. It is necessary to find an alternative source of rawmaterials, including those from plants. Moringa pterigospera Gaertn leaves wasselected because it contains iron and other nutritions. The purpose of this workwas to make instant powder formula for anti anemia using Moringa leave’s extractas an alternative for ferous suphate iron suplementation. The extraction wasperformed by Microwave Assisted Extraction method. Optimation of extractioncondition was performed by creating some variations in solvent composition (0-70% ethanol), microwave power (450 to 900 watts) and extraction time (3 to 10min). Iron content was determined by Atomic Absorption Spectrophotometer atwavelength of 248 nm. Instant powder formula was made in 3 concentrations ofsodium CMC as suspending agent. Results of the study showed that the mostoptimal extraction condition which resulted the highest iron content (2.4 mgiron/g extracts) achieved with 900 watts microwave power, 10 min extraction timeand aquademineralisata. According to 30 panelists of hedonic test, formula whichused 5% w/w of sodium CMC got the highest scores. Its powder form had 2.31%of loss on drying and 7.74 g/sec of flow rate for powder form and pH of 5.78,viscosity of 15.98 cps for reconstituted form.] |
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