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Total synthesis of bioactive natural products by palladium-catalyzed domino cyclization of allenes and related compounds

Shinsuke Inuki (Springer, 2012)

 Abstrak

The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved.

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 Metadata

No. Panggil : e20406115
Entri utama-Nama orang :
Subjek :
Penerbitan : Tokyo : Springer, 2012
Sumber Pengatalogan: LibUI eng rda
Tipe Konten: text
Tipe Media: computer
Tipe Pembawa: online resource
Deskripsi Fisik:
Tautan: http://link.springer.com/book/10.1007%2F978-4-431-54043-4
Lembaga Pemilik:
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No. Panggil No. Barkod Ketersediaan
e20406115 TERSEDIA
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