[Penduduk di daerah kumuh memiliki kemungkinan terpajan mikroba patogenyang lebih besar daripada penduduk yang tinggal di daerah di daerah non kumuh.Hal ini dapat dipengaruhi oleh gaya hidup mereka. Apabila terpajan mikrobapatogen sistem imun tubuh akan terpicu untuk melawan patogen tersebut. Salahsatu bagian dari sistem imun tubuh manusia adalah imunoglobulin atau antibodi,salah satu jenis globulin. Pembentukan globulin ini akan menekan sintesis jenisjenisprotein lain, salah satunya adalah albumin yang sangat diperlukan tubuh.Oleh karena itu, dilakukan penelitian untuk membandingkan rasio albuminglobulin pada penduduk daerah kumuh dan non kumuh. Penelitian cross sectionaldilakukan pada bulan Desember 2014 yang melibatkan 40 orang sampel daridaerah kumuh dan 40 orang dari daerah non kumuh dengan metode consecutivesampling. Berdasarkan hasil pemeriksaan darah yang diuji dengan metode uji Tindependen, rasio albumin globulin penduduk di daerah non kumuh lebih tinggidibanding rasio albumin globulin penduduk yang tinggal di daerah kumuh denganp = 0,000. Dari uji korelasi, didapatkan bahwa terdapat perbedaan antara rasioalbumin globulin dari sampel yang terinfeksi sejumlah jenis patogen dengan yangtidak terinfeksi namun tidak bermakna secara statistik dengan p = 0,169 dankoefisien korelasi ?0,113. Rasio prevalensi didapatkan 0,63 CI 95% (0,25-1,60).;People living inside of landfill area have a higher chance of being exposed topathogens compared to people living outside of landfill area. This can be affectedby their lifestyle. When exposed to pathogen, human?s immune system will betriggered to combat the pathogens. Immunoglobulin or antibody, a kind ofglobulin, is a part of the immune system. The synthesis of globulin will repress thesynthesis of other kinds of protein, one of them being albumin which is highlyneeded in the human body. Therefore, a research was conducted to compare thealbumin globulin ratio in people living inside and outside of landfill area. Thecross sectional study was conducted on December 2014 and involved 40 subjectsfrom inside landfill area and 40 subjects from outside landfill areas usingconsecutive sampling method. From blood examination result that has been testedusing T-test independent method, the albumin globulin ratio in people livingoutside of landfill area was higher compared to people living inside of landfillarea with p = 0.000. From correlation test, there was a difference of albuminglobulin ratio between people infected with certain pathogens and those who werenot but was not considered statistically significant with p = 0.169 and correlationcoefficient of ?0.113. Prevalence ratio was 0.63 CI 95% (0.25-1.60)., People living inside of landfill area have a higher chance of being exposed topathogens compared to people living outside of landfill area. This can be affectedby their lifestyle. When exposed to pathogen, human’s immune system will betriggered to combat the pathogens. Immunoglobulin or antibody, a kind ofglobulin, is a part of the immune system. The synthesis of globulin will repress thesynthesis of other kinds of protein, one of them being albumin which is highlyneeded in the human body. Therefore, a research was conducted to compare thealbumin globulin ratio in people living inside and outside of landfill area. Thecross sectional study was conducted on December 2014 and involved 40 subjectsfrom inside landfill area and 40 subjects from outside landfill areas usingconsecutive sampling method. From blood examination result that has been testedusing T-test independent method, the albumin globulin ratio in people livingoutside of landfill area was higher compared to people living inside of landfillarea with p = 0.000. From correlation test, there was a difference of albuminglobulin ratio between people infected with certain pathogens and those who werenot but was not considered statistically significant with p = 0.169 and correlationcoefficient of –0.113. Prevalence ratio was 0.63 CI 95% (0.25-1.60).] |