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Peranan biakan usap telinga dalam diagnosis sepsis awitan dini pada bayi baru lahir = The role of ear swabs culture in the diagnosis early onset sepsis of the newborn

Arum Gunarsih; Rinawati Rohsiswatmo, supervisor; Mulya Rahma Karyanti, supervisor ([Publisher not identified] , 2015)

 Abstrak

[ABSTRAK
Latar belakang. Sepsis neonatorum awitan dini (SNAD) adalah sindrom klinis
akibat respon sistemik terhadap infeksi pada awal kehidupan. Diagnosis SNAD
seringkali sulit karena gejala klinisnya tidak spesifik.
Tujuan. Mengetahui sensitivitas dan spesifisitas biakan usap telinga dalam
diagnosis SNAD.
Metode. Subjek penelitian adalah neonatus yang lahir di RSCM Jakarta dan RSU
Tangerang Selatan dengan diagnosis SNAD. Dilakukan pengambilan biakan dari
usapan telinga dan darah bayi.
Hasil. Diantara 50 subjek, terdapat 2 neonatus dengan biakan darah positif, dan 32
neonatus dengan biakan usap telinga positif. Hanya 1 subjek yang memiliki
kesesuaian jenis kuman yang tumbuh dari biakan darah dan biakan usap telinga.
Bakteri yang tumbuh pada biakan usap telinga sebagian besar adalah Gram postif
(62%). Biakan usap telinga mempunyai sensitivitas 64,7%, spesifisitas 36,4%,
nilai duga positif 34,3%, nilai duga negatif 66,6%, rasio kemungkinan positif
1,02, rasio kemungkinan negatif 0,97, dan, akurasi 46% untuk mendeteksi SNAD.
Simpulan. Ditemukan hasil biakan darah positif pada 2 subjek. Biakan usap
telinga memiliki sensitivitas 64,7%, spesifisitas 36,4%, nilai duga positif 34,3%,
nilai duga negatif 66,6%, rasio kemungkinan positif 1,02, rasio kemungkinan
negatif 0,97, dan akurasi 46% untuk mendeteksi SNAD.

ABSTRACT
Background. Early-onset neonatal sepsis (EOS) is a clinical syndrome due to
systemic response to infection in early life. EOS is often difficult to diagnosed
because the clinical symptoms are not specific.
Objective. The study aim to determine sensitivity and specificity of ear swabs
culture in the diagnosis of EOS.
Methods. Neonates born in the CMH Jakarta and Tangerang Selatan Hospital
who developed sepsis were studied. Swabs were collected for culture from baby’s
ear. Bacterias isolated from ear swabs cultured were correlated with those from
blood culture.
Results. Among 50 neonates studied, 2 neonates had positive blood cultured and
32 neonates had positive ear swabs cultured. Only one subject had suitability
types of bacterias that grew from blood and ear swabs. Bacteria grew from ear
swab cultured were predominantly Gram-positive (62%). Ear swabs cultured had
sensitivity 64.7%, specificity 36.4%, positive predictive value (PPV) 34.3%,
negative predictive value (NPV) 66.6%, positive likelihood ratio (PLR) 1.02,
negative likelihood ratio (NLR) 0.97, and accuracy 46% to detect EOS.
Conclusions. This study showed positive blood culture results were found in two
subjects. Ear swabs cultured had a sensitivity 64.7%, specificity 36.4%, PPV
34.3%, NPV 66.6%, PLR 1.02, NLR 0.97, and accuracy 46% to detect EOS, Background. Early-onset neonatal sepsis (EOS) is a clinical syndrome due to
systemic response to infection in early life. EOS is often difficult to diagnosed
because the clinical symptoms are not specific.
Objective. The study aim to determine sensitivity and specificity of ear swabs
culture in the diagnosis of EOS.
Methods. Neonates born in the CMH Jakarta and Tangerang Selatan Hospital
who developed sepsis were studied. Swabs were collected for culture from baby’s
ear. Bacterias isolated from ear swabs cultured were correlated with those from
blood culture.
Results. Among 50 neonates studied, 2 neonates had positive blood cultured and
32 neonates had positive ear swabs cultured. Only one subject had suitability
types of bacterias that grew from blood and ear swabs. Bacteria grew from ear
swab cultured were predominantly Gram-positive (62%). Ear swabs cultured had
sensitivity 64.7%, specificity 36.4%, positive predictive value (PPV) 34.3%,
negative predictive value (NPV) 66.6%, positive likelihood ratio (PLR) 1.02,
negative likelihood ratio (NLR) 0.97, and accuracy 46% to detect EOS.
Conclusions. This study showed positive blood culture results were found in two
subjects. Ear swabs cultured had a sensitivity 64.7%, specificity 36.4%, PPV
34.3%, NPV 66.6%, PLR 1.02, NLR 0.97, and accuracy 46% to detect EOS]

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No. Panggil : T-Pdf
Entri utama-Nama orang :
Entri tambahan-Nama orang :
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Subjek :
Penerbitan : [Place of publication not identified]: [Publisher not identified], 2015
Program Studi :
Bahasa : ind
Sumber Pengatalogan : LibUI ind rda
Tipe Konten : text
Tipe Media : computer
Tipe Carrier : online resource
Deskripsi Fisik : xvii, 86 pages : illustration ; 28 cm + appendix
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 3
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