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Nilai diagnostik CA125 asites pada penderita kanker ovarium dengan asites masif = Diagnostic value of CA125 of ascites fluid in ovarium cancer case

Jeri Indrawan; Andrijono, supervisor; Gatot Purwoto, examiner; Surahman Hakim, examiner; Kartiwa Hadi Nuryanto, examiner (Fakultas Kedokteran Universitas Indonesia, 2015)

 Abstrak

[Latar belakang : Angka ketahanan hidup dalam 5 tahun pasien penderita
keganasan kanker ovaeium rendah, karena > 70% kasus terlambat didiagnosis.
CA125 asites merupakan metode untuk memprediksi kanker ovarium pra bedah
sebelum dilakukan tindakan atau tatalaksanha selanjutnya.
Tujuan : Penelitian ini bertujuan untuk menurunkan angka kematian akibat
kanker ovarium stadium lanjut.
Metode : Uji ini adalah uji diagnostik dengan desain potong lintang. Penelitian
berlangsung dari Juli 2014 sampai Juni 2015 di Poli onkologi Departemen
Obstetri dan Ginekologi RSUPN Dr Cipto Mangunkusumo sampel sebanyak 41
kasus. Sampel diambil langsung dari pasien kanker ovarium dengan asites masif.
Selanjutnya sampel di analisa nilai sensitivitas dan spesifitasnya.
Hasil : Dari 41 orang subjek penelitian didapatkan nilai sensitivitas dan spesifitas
yang cukup baik dalam mendiagnosis kanker ovarium, berturut ? turut niali
sensitivitas dan spesifitasnya adalah 96% dan 100%. Pemeriksaan kadar CA125
asites dapat dipertimbangkan untuk digunakan sebagai salah satu tumor marker
untuk mendiagnosis kanker ovarium dengan asites masif.
Kesimpulan : Kadar CA125 asites memiliki nilai sensitivitas dan spesifitas 96% dan 100% untuk mendiagnosa kanker ovarium jenis sel epitel.;Background : Overall five-year survival rate of ovarian cancer is the lowest of
amongst gynecological malignancies, as it diagnosed in late stage diseases.
Preoperative CA125 level in ascites fluid is one of the method to guide the
subsequent management. This research aimed to improve ovarian cancer survival
rate.
Method :This study was a diagnostic study with cross-sectional review of CA125
level in ascites fluid of 41 ovarian malignancy patients in Obstetrics and
Gynecology Department of RSUPN Dr. Cipto Mangunkusumo to analyze its
sensitivity and specificity.
Results :This research showed a good sensitivity and specificity of CA125 level,
96 % and 100 % respectively. CA125 level in ascites fluid may consider as one of
the tumour marker to diagnose ovarian malignancy with massive ascited fluid.
Conclusion: CA125 level in ascites fluid had a good sensitivity and specificity to diagnose epithelial ovarian malignancy., Background : Overall five-year survival rate of ovarian cancer is the lowest of
amongst gynecological malignancies, as it diagnosed in late stage diseases.
Preoperative CA125 level in ascites fluid is one of the method to guide the
subsequent management. This research aimed to improve ovarian cancer survival
rate.
Method :This study was a diagnostic study with cross-sectional review of CA125
level in ascites fluid of 41 ovarian malignancy patients in Obstetrics and
Gynecology Department of RSUPN Dr. Cipto Mangunkusumo to analyze its
sensitivity and specificity.
Results :This research showed a good sensitivity and specificity of CA125 level,
96 % and 100 % respectively. CA125 level in ascites fluid may consider as one of
the tumour marker to diagnose ovarian malignancy with massive ascited fluid.
Conclusion: CA125 level in ascites fluid had a good sensitivity and specificity to diagnose epithelial ovarian malignancy.]

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No. Panggil : SP-PDF
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Entri tambahan-Nama badan :
Subjek :
Penerbitan : [Place of publication not identified]: Fakultas Kedokteran Universitas Indonesia, 2015
Program Studi :
Bahasa : ind
Sumber Pengatalogan : LibUI ind rda
Tipe Konten : text
Tipe Media : computer
Tipe Carrier : online resource
Deskripsi Fisik : xiv, 33 pages : ill. ; 28 cm.
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 3
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No. Panggil No. Barkod Ketersediaan
SP-PDF 16-17-646161912 TERSEDIA
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Tidak ada ulasan pada koleksi ini: 20417233
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