Phosphoinositides I: enzymes of synthesis and degradation
Tamas Balla, Matthias Wymann, John D.York ([Springer, ], 2012)
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| In two volumes, this book elucidates the crucial mechanisms that control the dynamics of phosphoinositide conversion. Starting out from phosphatidylinositol, a chain of lipid kinases collaborates to generate the oncogenic lipid phosphatidylinositol(3,4,5)-trisphosphate. For every phosphate group added, there are specific lipid kinases – and phosphatases to remove it. Additionally, phospholipases can cleave off the inositol head group and generate poly-phosphoinositols, which act as soluble signals in the cytosol. Volume I untangles the web of these enzymes and their products, and relates them to function in health and disease. Phosphoinositide 3-kinases and 3-phosphatases have received a special focus in volume I, and recent therapeutic developments in human disease are presented along with a historical perspective illustrating the impressive progress in the field. |
 Phosphoinositides I- Enzymes of Synthesis and Degradation.pdf :: Unduh
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| No. Panggil : | e20417501 |
| Entri utama-Nama orang : | |
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| Penerbitan : | Dordrecht: [Springer, ], 2012 |
| Sumber Pengatalogan: | LibUI eng rda |
| Tipe Konten: | text |
| Tipe Media: | computer |
| Tipe Pembawa: | online resource |
| Deskripsi Fisik: | |
| Tautan: | http://link.springer.com/book/10.1007%2F978-94-007-3012-0 |
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| No. Panggil | No. Barkod | Ketersediaan |
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| e20417501 | TERSEDIA |
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