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Aging research in yeast

Michael Breitenbach, S. Michal Jazwinski, Peter Laun ([Springer, ], 2012)

 Abstrak

This book discusses, mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses, the role of autophagy and mitophagy, the relationship of apoptosis to aging processe, the role of asymmetric segregation of damage in replicative aging, the role of replication stress, and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senescence (studied in yeast) and of cancer cells, including genome instability, are examined.

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No. Panggil : e20417848
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Subjek :
Penerbitan : Dordrecht: [Springer, ], 2012
Sumber Pengatalogan: LibUI eng rda
Tipe Konten: text
Tipe Media: unmediated
Tipe Pembawa: online resource
Deskripsi Fisik:
Tautan: http://link.springer.com/book/10.1007%2F978-94-007-2561-4
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