Influenza virus sialidase: a drug discovery target
Mark von Itzstein ([, Springer], 2012)
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This volume describes all aspects of the virus structure and function relevant to infection. The focus is on drug discovery of inhibitors to the enzyme sialidase, which plays a key role in the infectious lifecycle of the virus. Following an overview of the influenza virus, the haemagglutinin, the interactions with the cell receptors and the enzymology of virus sialidase, recent results in drug design are presented. These include a full coverage of the design, synthesis and evaluation of carbohydrate as well as non-carbohydrate influenza virus sialidase inhibitors. Further reviews of the clinical experience with influenza virus sialidase inhibitors and of the development of resistance to these inhibitor drugs complement the topic. |
Influenza Virus Sialidase - A Drug Discovery Target.pdf :: Unduh
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No. Panggil : | e20417994 |
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Penerbitan : | Netherlands: [, Springer], 2012 |
Sumber Pengatalogan: | LibUI eng rda |
Tipe Konten: | text |
Tipe Media: | computer |
Tipe Pembawa: | volume |
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Tautan: | http://link.springer.com/book/10.1007%2F978-3-7643-8927-7 |
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No. Panggil | No. Barkod | Ketersediaan |
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e20417994 | TERSEDIA |
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